Published in Nat Rev Microbiol on March 01, 2005
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Real-time attack on single Escherichia coli cells by the human antimicrobial peptide LL-37. Proc Natl Acad Sci U S A (2011) 1.48
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A complete lipopolysaccharide inner core oligosaccharide is required for resistance of Burkholderia cenocepacia to antimicrobial peptides and bacterial survival in vivo. J Bacteriol (2006) 1.46
Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process. Biophys J (2007) 1.44
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Transcriptome analysis of the responses of Staphylococcus aureus to antimicrobial peptides and characterization of the roles of vraDE and vraSR in antimicrobial resistance. BMC Genomics (2009) 1.39
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Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity. Proc Natl Acad Sci U S A (2011) 1.37
Insights into in vivo activities of lantibiotics from gallidermin and epidermin mode-of-action studies. Antimicrob Agents Chemother (2006) 1.36
Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization. PLoS Pathog (2010) 1.34
Inducible innate resistance of lung epithelium to infection. Annu Rev Physiol (2010) 1.34
Virulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression. J Exp Med (2008) 1.33
The role of antimicrobial peptides at the ocular surface. Ophthalmic Res (2008) 1.32
Salivary defense proteins: their network and role in innate and acquired oral immunity. Int J Mol Sci (2012) 1.32
Dual-color fluorescence-burst analysis to probe protein efflux through the mechanosensitive channel MscL. Biophys J (2006) 1.32
Structure, membrane orientation, mechanism, and function of pexiganan--a highly potent antimicrobial peptide designed from magainin. Biochim Biophys Acta (2008) 1.31
Infectious Disease: Connecting Innate Immunity to Biocidal Polymers. Mater Sci Eng R Rep (2007) 1.30
Models of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels. Biophys J (2008) 1.30
Induction of a peptide with activity against a broad spectrum of pathogens in the Aedes aegypti salivary gland, following Infection with Dengue Virus. PLoS Pathog (2011) 1.30
Antimicrobial peptides in 2014. Pharmaceuticals (Basel) (2015) 1.30
De novo designed synthetic mimics of antimicrobial peptides. Curr Opin Biotechnol (2008) 1.30
Will new generations of modified antimicrobial peptides improve their potential as pharmaceuticals? Int J Antimicrob Agents (2011) 1.28
Permeabilization of fungal hyphae by the plant defensin NaD1 occurs through a cell wall-dependent process. J Biol Chem (2010) 1.28
Escherichia coli cell surface perturbation and disruption induced by antimicrobial peptides BP100 and pepR. J Biol Chem (2010) 1.27
Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins. Proc Natl Acad Sci U S A (2007) 1.27
Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II. FEBS Lett (2010) 1.26
Through the looking glass, mechanistic insights from enantiomeric human defensins. J Biol Chem (2009) 1.25
The Staphylococcus aureus two-component regulatory system, GraRS, senses and confers resistance to selected cationic antimicrobial peptides. Infect Immun (2011) 1.25
Synthetic mimic of antimicrobial peptide with nonmembrane-disrupting antibacterial properties. Biomacromolecules (2008) 1.25
DAMPD: a manually curated antimicrobial peptide database. Nucleic Acids Res (2011) 1.24
Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens. Antimicrob Agents Chemother (2007) 1.24
Resistance of Neisseria gonorrhoeae to non-oxidative killing by adherent human polymorphonuclear leucocytes. Cell Microbiol (2009) 1.24
The role of antimicrobial peptides in preventing multidrug-resistant bacterial infections and biofilm formation. Int J Mol Sci (2011) 1.23
Natural and synthetic cathelicidin peptides with anti-microbial and anti-biofilm activity against Staphylococcus aureus. BMC Microbiol (2011) 1.22
LAMP: A Database Linking Antimicrobial Peptides. PLoS One (2013) 1.21
Comparison of biophysical and biologic properties of alpha-helical enantiomeric antimicrobial peptides. Chem Biol Drug Des (2006) 1.20
Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via interaction with negative intrinsic curvature lipids. Proc Natl Acad Sci U S A (2008) 1.20
Insight into invertebrate defensin mechanism of action: oyster defensins inhibit peptidoglycan biosynthesis by binding to lipid II. J Biol Chem (2010) 1.19
Alpha-helical cationic antimicrobial peptides: relationships of structure and function. Protein Cell (2010) 1.19
Marine sponge derived natural products between 2001 and 2010: trends and opportunities for discovery of bioactives. Mar Drugs (2014) 1.19
Host defense peptides in the oral cavity and the lung: similarities and differences. J Dent Res (2008) 1.19
Analysis of the networks controlling the antimicrobial-peptide-dependent induction of Klebsiella pneumoniae virulence factors. Infect Immun (2011) 1.19
Naturally processed dermcidin-derived peptides do not permeabilize bacterial membranes and kill microorganisms irrespective of their charge. Antimicrob Agents Chemother (2006) 1.18
Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels. Biophys J (2009) 1.18
Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics. PLoS One (2008) 1.18
Anti-infective activities of lactobacillus strains in the human intestinal microbiota: from probiotics to gastrointestinal anti-infectious biotherapeutic agents. Clin Microbiol Rev (2014) 1.17
Antibacterial membrane attack by a pore-forming intestinal C-type lectin. Nature (2013) 1.17
Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus. PLoS One (2010) 1.17
Antimicrobial protegrin-1 forms amyloid-like fibrils with rapid kinetics suggesting a functional link. Biophys J (2011) 1.17
Adding selectivity to antimicrobial peptides: rational design of a multidomain peptide against Pseudomonas spp. Antimicrob Agents Chemother (2006) 1.17
An N-terminal domain of adenovirus protein VI fragments membranes by inducing positive membrane curvature. Virology (2010) 1.17
Cationic antimicrobial polymers and their assemblies. Int J Mol Sci (2013) 1.16
Common mechanism unites membrane poration by amyloid and antimicrobial peptides. Proc Natl Acad Sci U S A (2013) 1.16
Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold. Antimicrob Agents Chemother (2010) 1.15
Manipulating Bacterial Communities by in situ Microbiome Engineering. Trends Genet (2016) 1.14
Evidence that cathelicidin peptide LL-37 may act as a functional ligand for CXCR2 on human neutrophils. Eur J Immunol (2009) 1.14
Conformation and membrane orientation of amphiphilic helical peptides by oriented circular dichroism. Biophys J (2008) 1.14
Structure and dynamics of cationic membrane peptides and proteins: insights from solid-state NMR. Protein Sci (2011) 1.13
Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence-determinant stability. Microbiologyopen (2012) 1.13
On the mechanism of pore formation by melittin. J Biol Chem (2008) 1.13
Proteolysis of human thrombin generates novel host defense peptides. PLoS Pathog (2010) 1.12
Antimicrobial peptides with cell-penetrating peptide properties and vice versa. Eur Biophys J (2011) 1.12
Therapeutic antimicrobial peptides may compromise natural immunity. Biol Lett (2012) 1.12
Phosphoinositide-mediated oligomerization of a defensin induces cell lysis. Elife (2014) 1.11
Influence of lipid composition on membrane activity of antimicrobial phenylene ethynylene oligomers. J Phys Chem B (2008) 1.11
Reduced mucosal antimicrobial activity in Crohn's disease of the colon. Gut (2007) 1.11
Host defense peptides in wound healing. Mol Med (2008) 1.10
Peptide-lipid huge toroidal pore, a new antimicrobial mechanism mediated by a lactococcal bacteriocin, lacticin Q. Antimicrob Agents Chemother (2009) 1.10
Concerted evolution of two novel protein families in Caenorhabditis species. Genetics (2006) 1.10
Decreased outer membrane permeability protects mycobacteria from killing by ubiquitin-derived peptides. Mol Microbiol (2009) 1.09
Identification and gene expression analysis of a taxonomically restricted cysteine-rich protein family in reef-building corals. PLoS One (2009) 1.09
A calmodulin-dependent translocation pathway for small secretory proteins. Cell (2011) 1.09
Specific RNA binding to ordered phospholipid bilayers. Nucleic Acids Res (2006) 1.08
Human antimicrobial peptide LL-37 inhibits adhesion of Candida albicans by interacting with yeast cell-wall carbohydrates. PLoS One (2011) 1.08
Structural convergence among diverse, toxic beta-sheet ion channels. J Phys Chem B (2010) 1.08