Published in Nature on November 20, 2013
Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation. Cell Host Microbe (2016) 2.17
Structural basis for the prion-like MAVS filaments in antiviral innate immunity. Elife (2014) 1.56
Antimicrobial peptides in 2014. Pharmaceuticals (Basel) (2015) 1.30
A plug release mechanism for membrane permeation by MLKL. Structure (2014) 1.29
Human antimicrobial peptides and proteins. Pharmaceuticals (Basel) (2014) 1.23
Microbiota-mediated inflammation and antimicrobial defense in the intestine. Annu Rev Immunol (2015) 1.23
Pore-forming toxins: ancient, but never really out of fashion. Nat Rev Microbiol (2015) 1.08
Commensal bacteria mediated defenses against pathogens. Curr Opin Immunol (2014) 0.93
Associations with rhizosphere bacteria can confer an adaptive advantage to plants. Nat Plants (2015) 0.92
Anatomical localization of commensal bacteria in immune cell homeostasis and disease. Immunol Rev (2014) 0.92
Mechanistic links between gut microbial community dynamics, microbial functions and metabolic health. World J Gastroenterol (2014) 0.86
The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity. Curr Opin Rheumatol (2015) 0.86
Signaling in Host-Associated Microbial Communities. Cell (2016) 0.86
Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia. Nature (2016) 0.86
Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein. EMBO Rep (2015) 0.83
Lantibiotic immunity: inhibition of nisin mediated pore formation by NisI. PLoS One (2014) 0.81
Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide. Mucosal Immunol (2014) 0.81
Stress as a Normal Cue in the Symbiotic Environment. Trends Microbiol (2016) 0.80
Antimicrobial effectors in the nematode Caenorhabditis elegans: an outgroup to the Arthropoda. Philos Trans R Soc Lond B Biol Sci (2016) 0.80
The Reg3α (HIP/PAP) Lectin Suppresses Extracellular Oxidative Stress in a Murine Model of Acute Liver Failure. PLoS One (2015) 0.79
Expression and Significance of the HIP/PAP and RegIIIγ Antimicrobial Peptides during Mammalian Urinary Tract Infection. PLoS One (2015) 0.78
Continuum descriptions of membranes and their interaction with proteins: Towards chemically accurate models. Biochim Biophys Acta (2016) 0.78
Antimicrobial Peptides Targeting Gram-Positive Bacteria. Pharmaceuticals (Basel) (2016) 0.77
Calcium and Magnesium Ions Are Membrane-Active against Stationary-Phase Staphylococcus aureus with High Specificity. Sci Rep (2016) 0.76
Transcriptomic and proteomic insights into innate immunity and adaptations to a symbiotic lifestyle in the gutless marine worm Olavius algarvensis. BMC Genomics (2016) 0.75
Intrinsic Defense Mechanisms of the Intestinal Epithelium. Cell Host Microbe (2016) 0.75
Secretion of biologically active pancreatitis-associated protein I (PAP) by genetically modified dairy Lactococcus lactis NZ9000 in the prevention of intestinal mucositis. Microb Cell Fact (2017) 0.75
Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7. PLoS Genet (2017) 0.75
Interaction between the gut microbiome and mucosal immune system. Mil Med Res (2017) 0.75
Defensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut. Crit Rev Biochem Mol Biol (2016) 0.75
Commensal Microbiome Promotes Resistance to Local and Systemic Infections. Chin Med J (Engl) (2015) 0.75
Interleukin-22-Induced Antimicrobial Phospholipase A2 Group IIA Mediates Protective Innate Immunity of Nonhematopoietic Cells against Listeria monocytogenes. Infect Immun (2015) 0.75
The Gut Epithelial Receptor LRRC19 Promotes the Recruitment of Immune Cells and Gut Inflammation. Cell Rep (2016) 0.75
Maintenance of gut homeostasis by the mucosal immune system. Proc Jpn Acad Ser B Phys Biol Sci (2016) 0.75
γδ T cells in homeostasis and host defence of epithelial barrier tissues. Nat Rev Immunol (2017) 0.75
Citrobacter rodentium: a model enteropathogen for understanding the interplay of innate and adaptive components of type 3 immunity. Mucosal Immunol (2017) 0.75
Human Gut Microbiota: Toward an Ecology of Disease. Front Microbiol (2017) 0.75
Antimicrobial peptides of multicellular organisms. Nature (2002) 23.50
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol (2005) 13.69
Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science (2006) 9.95
The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. Science (2011) 7.07
Environment and exposure to solvent of protein atoms. Lysozyme and insulin. J Mol Biol (1973) 6.76
Reconstitution of cell membrane structure in vitro and its transformation into an excitable system. Nature (1962) 5.33
Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes. Proc Natl Acad Sci U S A (1990) 3.90
Formation of "solvent-free" black lipid bilayer membranes from glyceryl monooleate dispersed in squalene. Biophys J (1978) 3.26
Energetics of inclusion-induced bilayer deformations. Biophys J (1998) 3.19
Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat Struct Mol Biol (2006) 3.14
Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine. Neuron (2001) 3.10
Human α-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets. Science (2012) 2.44
Mannose-binding lectin and innate immunity. Immunol Rev (2009) 2.08
Structure and fluctuations of charged phosphatidylserine bilayers in the absence of salt. Biophys J (2004) 2.08
Refolding, purification, and characterization of human and murine RegIII proteins expressed in Escherichia coli. Protein Expr Purif (2006) 1.83
Closer look at structure of fully hydrated fluid phase DPPC bilayers. Biophys J (2006) 1.82
Immortalization of mouse intestinal epithelial cells by the SV40-large T gene. Phenotypic and immune characterization of the MODE-K cell line. J Immunol Methods (1993) 1.72
Electron microscopic analysis of KvAP voltage-dependent K+ channels in an open conformation. Nature (2004) 1.61
Universal behavior of membranes with sterols. Biophys J (2005) 1.57
Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment. J Biol Chem (2008) 1.35
Molecular basis for peptidoglycan recognition by a bactericidal lectin. Proc Natl Acad Sci U S A (2010) 1.34
Curvature and bending constants for phosphatidylserine-containing membranes. Biophys J (2003) 1.24
Antimicrobial properties of amyloid peptides. Mol Pharm (2011) 1.02
The membrane-bound structure and topology of a human α-defensin indicate a dimer pore mechanism for membrane disruption. Biochemistry (2010) 1.01
Membrane bending is critical for the stability of voltage sensor segments in the membrane. J Gen Physiol (2012) 0.97
Human pancreatitis-associated protein forms fibrillar aggregates with a native-like conformation. J Biol Chem (2006) 0.91
Membrane-binding properties of the Factor VIII C2 domain. Biochem J (2011) 0.90
Quantitative analysis of protein-lipid interactions using tryptophan fluorescence. Sci Signal (2009) 0.86