PubRank

Donalyn Scheuner

Author PubWeight™ 70.31‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J Cell Biol 2005 9.25
2 A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 2005 7.98
3 Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway. Proc Natl Acad Sci U S A 2001 5.59
4 Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. J Clin Invest 2008 4.30
5 ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth. EMBO J 2005 3.79
6 Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2. EMBO J 2004 3.77
7 The unfolded protein response in nutrient sensing and differentiation. Nat Rev Mol Cell Biol 2002 3.56
8 Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells. Cell Metab 2009 3.28
9 The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. J Clin Invest 2005 3.16
10 Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses. Mol Cell Biol 2003 3.01
11 Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol Cell Biol 2004 3.00
12 Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure. J Biol Chem 2005 2.85
13 The zipper model of translational control: a small upstream ORF is the switch that controls structural remodeling of an mRNA leader. Cell 2003 2.50
14 Activation of GCN2 in UV-irradiated cells inhibits translation. Curr Biol 2002 2.02
15 Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development. Proc Natl Acad Sci U S A 2009 1.68
16 Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity. Cell Host Microbe 2010 1.56
17 Ultraviolet light activates NFkappaB through translational inhibition of IkappaBalpha synthesis. J Biol Chem 2004 1.36
18 eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress. J Biol Chem 2010 1.28
19 Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency. Mol Biol Cell 2010 1.25
20 Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression. Cell Metab 2005 1.23
21 Tumor suppression by PTEN requires the activation of the PKR-eIF2alpha phosphorylation pathway. Sci Signal 2009 1.11
22 Phosphorylation of eukaryotic translation initiation factor 2alpha coordinates rRNA transcription and translation inhibition during endoplasmic reticulum stress. Mol Cell Biol 2009 1.10
23 Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells. Endocrinology 2006 1.07
24 In vivo replication of an ICP34.5 second-site suppressor mutant following corneal infection correlates with in vitro regulation of eIF2 alpha phosphorylation. J Virol 2003 0.89
25 Novel function of PERK as a mediator of force-induced apoptosis. J Biol Chem 2008 0.88