Published in J Biol Chem on January 31, 2005
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J Cell Biol (2005) 9.25
RNA granules. J Cell Biol (2006) 7.79
Angiogenin cleaves tRNA and promotes stress-induced translational repression. J Cell Biol (2009) 4.07
Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2alpha phosphorylation. Mol Biol Cell (2006) 2.84
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. J Biol Chem (2010) 2.61
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Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. J Clin Invest (2010) 2.18
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Reprogramming mRNA translation during stress. Curr Opin Cell Biol (2008) 1.92
LINE-1 ORF1 protein localizes in stress granules with other RNA-binding proteins, including components of RNA interference RNA-induced silencing complex. Mol Cell Biol (2007) 1.79
Reovirus induces and benefits from an integrated cellular stress response. J Virol (2006) 1.74
Hypoxic inhibition of nonsense-mediated RNA decay regulates gene expression and the integrated stress response. Mol Cell Biol (2008) 1.68
Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival. Mol Cell (2008) 1.67
Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2(alpha) phosphorylation at Thr169. J Cell Sci (2008) 1.64
Rotavirus infection induces the phosphorylation of eIF2alpha but prevents the formation of stress granules. J Virol (2007) 1.49
Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress. J Biol Chem (2012) 1.47
Regulation of stress granules in virus systems. Trends Microbiol (2012) 1.46
Anti-inflammatory lipid mediator 15d-PGJ2 inhibits translation through inactivation of eIF4A. EMBO J (2007) 1.42
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Emerging role of angiogenin in stress response and cell survival under adverse conditions. J Cell Physiol (2012) 1.38
Stable formation of compositionally unique stress granules in virus-infected cells. J Virol (2010) 1.34
RNA under attack: cellular handling of RNA damage. Crit Rev Biochem Mol Biol (2009) 1.32
Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis. Haematologica (2009) 1.32
Hypoxia potentiates microRNA-mediated gene silencing through posttranslational modification of Argonaute2. Mol Cell Biol (2011) 1.32
ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases. Sci Signal (2016) 1.29
OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress. Mol Cell Biol (2010) 1.28
Metazoan stress granule assembly is mediated by P-eIF2alpha-dependent and -independent mechanisms. RNA (2009) 1.23
Formation of antiviral cytoplasmic granules during orthopoxvirus infection. J Virol (2010) 1.18
Stress granules, P-bodies and cancer. Biochim Biophys Acta (2014) 1.17
Irreversible translation arrest in the reperfused brain. J Cereb Blood Flow Metab (2006) 1.15
Influenza a virus host shutoff disables antiviral stress-induced translation arrest. PLoS Pathog (2014) 1.14
Translation suppression promotes stress granule formation and cell survival in response to cold shock. Mol Biol Cell (2012) 1.13
Large G3BP-induced granules trigger eIF2α phosphorylation. Mol Biol Cell (2012) 1.10
Mammalian orthoreovirus particles induce and are recruited into stress granules at early times postinfection. J Virol (2009) 1.08
Angiogenin-mediated rRNA transcription in cancer and neurodegeneration. Int J Biochem Mol Biol (2010) 1.06
The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle. J Virol (2010) 1.04
The chemotherapeutic agent bortezomib induces the formation of stress granules. Cancer Cell Int (2010) 1.02
Translation of cIAP2 mRNA is mediated exclusively by a stress-modulated ribosome shunt. Mol Cell Biol (2008) 1.00
Stress puts TIA on TOP. Genes Dev (2011) 1.00
Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation. Cell Metab (2013) 1.00
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Eukaryotic initiation factor 2 (eIF2) signaling regulates proinflammatory cytokine expression and bacterial invasion. J Biol Chem (2012) 0.97
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Human Cytomegalovirus pTRS1 and pIRS1 Antagonize Protein Kinase R To Facilitate Virus Replication. J Virol (2016) 0.92
Mechanistic insights into mammalian stress granule dynamics. J Cell Biol (2016) 0.91
Inactivation of the mTORC1-eukaryotic translation initiation factor 4E pathway alters stress granule formation. Mol Cell Biol (2013) 0.91
Sam68 relocalization into stress granules in response to oxidative stress through complexing with TIA-1. Exp Cell Res (2009) 0.91
Surviving hypoxia by modulation of mRNA translation rate. J Cell Mol Med (2009) 0.91
How do trypanosomes change gene expression in response to the environment? Protoplasma (2011) 0.90
SMN deficiency reduces cellular ability to form stress granules, sensitizing cells to stress. Cell Mol Neurobiol (2011) 0.90
Macromolecular crowding regulates assembly of mRNA stress granules after osmotic stress: new role for compatible osmolytes. J Biol Chem (2011) 0.89
Translational attenuation differentially alters the fate of disease-associated fibulin proteins. FASEB J (2012) 0.88
Herpes simplex virus 2 infection impacts stress granule accumulation. J Virol (2012) 0.86
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SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation. PLoS Genet (2015) 0.85
Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease. EBioMedicine (2015) 0.85
Sorafenib, a multikinase inhibitor, induces formation of stress granules in hepatocarcinoma cells. Oncotarget (2015) 0.85
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The eIF4E-binding proteins are modifiers of cytoplasmic eIF4E relocalization during the heat shock response. Am J Physiol Cell Physiol (2009) 0.82
mRNA decapping enzyme 1a (Dcp1a)-induced translational arrest through protein kinase R (PKR) activation requires the N-terminal enabled vasodilator-stimulated protein homology 1 (EVH1) domain. J Biol Chem (2013) 0.82
The herpes simplex virus 2 virion-associated ribonuclease vhs interferes with stress granule formation. J Virol (2014) 0.81
RNA granule assembly and disassembly modulated by nuclear factor associated with double-stranded RNA 2 and nuclear factor 45. J Biol Chem (2014) 0.81
TORC2 mediates the heat stress response in Drosophila by promoting the formation of stress granules. J Cell Sci (2015) 0.81
Activation of stress response pathways promotes formation of antiviral granules and restricts virus replication. Mol Cell Biol (2014) 0.81
The role of molecular microtubule motors and the microtubule cytoskeleton in stress granule dynamics. Int J Cell Biol (2011) 0.81
The activities of the Yersinia protein kinase A (YpkA) and outer protein J (YopJ) virulence factors converge on an eIF2alpha kinase. J Biol Chem (2009) 0.81
Arsenite-induced stress granule formation is inhibited by elevated levels of reduced glutathione in West Nile virus-infected cells. PLoS Pathog (2017) 0.80
Hepatic heme-regulated inhibitor (HRI) eukaryotic initiation factor 2alpha kinase: a protagonist of heme-mediated translational control of CYP2B enzymes and a modulator of basal endoplasmic reticulum stress tone. Mol Pharmacol (2010) 0.80
Amino acids 78 and 79 of Mammalian Orthoreovirus protein µNS are necessary for stress granule localization, core protein λ2 interaction, and de novo virus replication. Virology (2013) 0.80
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Stress response pathways in ameloblasts: implications for amelogenesis and dental fluorosis. Cells (2012) 0.80
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BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism. Autophagy (2016) 0.78
Stress-induced start codon fidelity regulates arsenite-inducible regulatory particle-associated protein (AIRAP) translation. J Biol Chem (2014) 0.78
Stress granules contribute to α-globin homeostasis in differentiating erythroid cells. Biochem Biophys Res Commun (2012) 0.77
Characterization of Fragile X Mental Retardation Protein granules formation and dynamics in Drosophila. Biol Open (2012) 0.77
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The host-encoded Heme Regulated Inhibitor (HRI) facilitates virulence-associated activities of bacterial pathogens. PLoS One (2013) 0.77
A map of the arenavirus nucleoprotein-host protein interactome reveals that Junín virus selectively impairs the antiviral activity of PKR. J Virol (2017) 0.76
Spatio-temporal Dynamics and Mechanisms of Stress Granule Assembly. PLoS Comput Biol (2015) 0.76
Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress. Oncotarget (2016) 0.76
N-terminal hydrophobic amino acids of activating transcription factor 5 (ATF5) protein confer interleukin 1β (IL-1β)-induced stabilization. J Biol Chem (2013) 0.76
DDX3 Interacts with Influenza A Virus NS1 and NP Proteins and Exerts Antiviral Function through Regulation of Stress Granule Formation. J Virol (2016) 0.76
Molecular mechanisms of mTOR regulation by stress. Mol Cell Oncol (2014) 0.76
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15-deoxyspergualin inhibits eukaryotic protein synthesis through eIF2alpha phosphorylation. Biochem J (2007) 0.76
Diverse Strategies Used by Picornaviruses to Escape Host RNA Decay Pathways. Viruses (2016) 0.75
Casein Kinase 2 is linked to stress granule dynamics through phosphorylation of the stress granule nucleating protein G3BP1. Mol Cell Biol (2016) 0.75
Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses. PLoS Pathog (2016) 0.75
Upstream Open Reading Frames Located in the Leader of Protein Kinase Mζ mRNA Regulate Its Translation. Front Mol Neurosci (2016) 0.75
The mammalian unfolded protein response. Annu Rev Biochem (2005) 16.31
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J Cell Biol (2005) 9.25
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science (2005) 7.98
RNA granules. J Cell Biol (2006) 7.79
A trip to the ER: coping with stress. Trends Cell Biol (2004) 7.67
From endoplasmic-reticulum stress to the inflammatory response. Nature (2008) 7.17
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol (2006) 6.45
ER stress and the unfolded protein response. Mutat Res (2005) 6.43
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Stress granules: the Tao of RNA triage. Trends Biochem Sci (2008) 6.27
Stress granule assembly is mediated by prion-like aggregation of TIA-1. Mol Biol Cell (2004) 6.04
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Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway. Proc Natl Acad Sci U S A (2001) 5.59
Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell (2002) 5.20
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Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell (2006) 5.10
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Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol (2003) 4.77
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Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. J Clin Invest (2008) 4.30
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. Dev Cell (2008) 4.26
MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. EMBO J (2004) 4.08
Angiogenin cleaves tRNA and promotes stress-induced translational repression. J Cell Biol (2009) 4.07
Endoplasmic reticulum stress in liver disease. J Hepatol (2010) 3.90
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ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth. EMBO J (2005) 3.79
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Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol Cell Biol (2006) 3.31
Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells. Cell Metab (2009) 3.28
Angiogenin-induced tRNA fragments inhibit translation initiation. Mol Cell (2011) 3.23
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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4. Nature (2004) 3.18
The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. J Clin Invest (2005) 3.16
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ARE-mRNA degradation requires the 5'-3' decay pathway. EMBO Rep (2006) 3.01
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Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol Cell Biol (2004) 3.00
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Signaling the unfolded protein response from the endoplasmic reticulum. J Biol Chem (2004) 2.87
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A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly. Nat Cell Biol (2008) 2.76
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The subaxial cervical spine injury classification system: a novel approach to recognize the importance of morphology, neurology, and integrity of the disco-ligamentous complex. Spine (Phila Pa 1976) (2007) 2.37
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Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response. J Biol Chem (2004) 2.29
HuR as a negative posttranscriptional modulator in inflammation. Mol Cell (2005) 2.27
Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation. Mol Biol Cell (2005) 2.27
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The role of p58IPK in protecting the stressed endoplasmic reticulum. Mol Biol Cell (2007) 2.20
PKR protects colonic epithelium against colitis through the unfolded protein response and prosurvival signaling. Inflamm Bowel Dis (2012) 2.20
Knockout mice lacking steroidogenic factor 1 are a novel genetic model of hypothalamic obesity. Endocrinology (2002) 2.19
ER stress controls iron metabolism through induction of hepcidin. Science (2009) 2.18
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The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis. EMBO J (2011) 2.08