Published in Circ Res on February 10, 2005
A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates. Biophys J (2008) 4.22
Orphaned ryanodine receptors in the failing heart. Proc Natl Acad Sci U S A (2006) 3.99
T-tubule remodeling during transition from hypertrophy to heart failure. Circ Res (2010) 3.57
T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction. J Physiol (2006) 2.50
Repair of the injured adult heart involves new myocytes potentially derived from resident cardiac stem cells. Circ Res (2011) 2.02
The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle. J Mol Med (Berl) (2009) 1.94
Excitation-contraction coupling and mitochondrial energetics. Basic Res Cardiol (2007) 1.74
Intermolecular failure of L-type Ca2+ channel and ryanodine receptor signaling in hypertrophy. PLoS Biol (2007) 1.70
Ultrastructural remodelling of Ca(2+) signalling apparatus in failing heart cells. Cardiovasc Res (2012) 1.65
Enhanced ryanodine receptor-mediated calcium leak determines reduced sarcoplasmic reticulum calcium content in chronic canine heart failure. Biophys J (2007) 1.48
Emerging mechanisms of T-tubule remodelling in heart failure. Cardiovasc Res (2013) 1.35
CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes. Circ Res (2009) 1.33
Cardiac alternans induced by fibroblast-myocyte coupling: mechanistic insights from computational models. Am J Physiol Heart Circ Physiol (2009) 1.33
Late sodium current in failing heart: friend or foe? Prog Biophys Mol Biol (2007) 1.23
Angiotensin II and stretch activate NADPH oxidase to destabilize cardiac Kv4.3 channel mRNA. Circ Res (2006) 1.20
Late sodium current contributes to diastolic cell Ca2+ accumulation in chronic heart failure. J Physiol Sci (2010) 1.18
There goes the neighborhood: pathological alterations in T-tubule morphology and consequences for cardiomyocyte Ca2+ handling. J Biomed Biotechnol (2010) 1.17
T-wave alternans and arrhythmogenesis in cardiac diseases. Front Physiol (2010) 1.09
Control of Ca2+ release by action potential configuration in normal and failing murine cardiomyocytes. Biophys J (2010) 0.96
Late sodium current is a new therapeutic target to improve contractility and rhythm in failing heart. Cardiovasc Hematol Agents Med Chem (2008) 0.96
The transverse-axial tubular system of cardiomyocytes. Cell Mol Life Sci (2013) 0.93
Dilated cardiomyopathy with increased SR Ca2+ loading preceded by a hypercontractile state and diastolic failure in the alpha(1C)TG mouse. PLoS One (2009) 0.91
AUF1 is upregulated by angiotensin II to destabilize cardiac Kv4.3 channel mRNA. J Mol Cell Cardiol (2008) 0.90
Targeting cardiomyocyte Ca2+ homeostasis in heart failure. Curr Pharm Des (2015) 0.87
NFAT-dependent excitation-transcription coupling in heart. Circ Res (2008) 0.85
Ca2+ cycling in heart cells from ground squirrels: adaptive strategies for intracellular Ca2+ homeostasis. PLoS One (2011) 0.84
Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity. Biophys J (2013) 0.83
Effect of fosinopril on the transient outward potassium current of hypertrophied left ventricular myocardium in the spontaneously hypertensive rat. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.82
Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure. Front Physiol (2012) 0.82
Delayed endosome-dependent CamKII and p38 kinase signaling in cardiomyocytes destabilizes Kv4.3 mRNA. J Mol Cell Cardiol (2012) 0.80
Simvastatin modulates remodeling of Kv4.3 expression in rat hypertrophied cardiomyocytes. Int J Biol Sci (2012) 0.78
How does the shape of the cardiac action potential control calcium signaling and contraction in the heart? J Mol Cell Cardiol (2010) 0.76
Regulation of Cardiomyocyte T-Tubular Structure: Opportunities for Therapy. Curr Heart Fail Rep (2017) 0.75
Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure. J Clin Invest (2007) 3.13
Bone marrow cells adopt the cardiomyogenic fate in vivo. Proc Natl Acad Sci U S A (2007) 3.06
Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circ Res (2011) 2.99
Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging. Circulation (2009) 2.96
Cellular basis of abnormal calcium transients of failing human ventricular myocytes. Circ Res (2003) 2.86
Adrenergic regulation of cardiac contractility does not involve phosphorylation of the cardiac ryanodine receptor at serine 2808. Circ Res (2008) 2.73
L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices. Circ Res (2002) 2.62
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. J Gen Physiol (2006) 2.58
Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy. J Am Coll Cardiol (2011) 2.40
Are resident c-Kit+ cardiac stem cells really all that are needed to mend a broken heart? Circ Res (2013) 2.40
Pim-1 regulates cardiomyocyte survival downstream of Akt. Nat Med (2007) 2.39
Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties. Circ Res (2007) 2.38
Animal models of heart failure: a scientific statement from the American Heart Association. Circ Res (2012) 2.31
Constitutively active L-type Ca2+ channels. Proc Natl Acad Sci U S A (2005) 2.24
G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure. Circ Res (2008) 2.22
Na(+)-Ca(2+) exchange current and submembrane [Ca(2+)] during the cardiac action potential. Circ Res (2002) 2.21
Hyperphosphorylation of the cardiac ryanodine receptor at serine 2808 is not involved in cardiac dysfunction after myocardial infarction. Circ Res (2012) 2.16
Repair of the injured adult heart involves new myocytes potentially derived from resident cardiac stem cells. Circ Res (2011) 2.02
Ca2+ influx-induced sarcoplasmic reticulum Ca2+ overload causes mitochondrial-dependent apoptosis in ventricular myocytes. Circ Res (2005) 2.02
Still making the case against prehospital intubation: a rat hemorrhagic shock model. J Trauma Acute Care Surg (2012) 1.97
Elevated Ca2+ sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells. Am J Physiol Cell Physiol (2009) 1.93
Mechanisms underlying heterogeneous Ca2+ sparklet activity in arterial smooth muscle. J Gen Physiol (2006) 1.86
VEGF-C gene therapy augments postnatal lymphangiogenesis and ameliorates secondary lymphedema. J Clin Invest (2003) 1.84
Abnormal frequency-dependent responses represent the pathophysiologic signature of contractile failure in human myocardium. J Mol Cell Cardiol (2004) 1.81
Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension. J Clin Invest (2003) 1.79
Comparative evaluation of FGF-2-, VEGF-A-, and VEGF-C-induced angiogenesis, lymphangiogenesis, vascular fenestrations, and permeability. Circ Res (2004) 1.74
AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension. Circ Res (2008) 1.72
Increased cardiac myocyte progenitors in failing human hearts. Circulation (2008) 1.68
Lymphangiogenesis-mediated shedding of LAM cell clusters as a mechanism for dissemination in lymphangioleiomyomatosis. Am J Surg Pathol (2005) 1.66
Differential calcineurin/NFATc3 activity contributes to the Ito transmural gradient in the mouse heart. Circ Res (2006) 1.64
Nuclear targeting of Akt enhances ventricular function and myocyte contractility. Circ Res (2005) 1.62
Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels. Circ Res (2010) 1.59
AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus. Circ Res (2013) 1.59
Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach. Circ Res (2009) 1.58
Activation of NFATc3 down-regulates the beta1 subunit of large conductance, calcium-activated K+ channels in arterial smooth muscle and contributes to hypertension. J Biol Chem (2006) 1.58
Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury. Circ Res (2011) 1.55
Increased coupled gating of L-type Ca2+ channels during hypertension and Timothy syndrome. Circ Res (2010) 1.55
Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction. Circulation (2012) 1.52
[Na+]i handling in the failing human heart. Cardiovasc Res (2003) 1.51
alpha1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice. J Clin Invest (2009) 1.51
Vascular endothelial growth factor D is dispensable for development of the lymphatic system. Mol Cell Biol (2005) 1.47
How to obtain a National Heart, Lung, and Blood Institute-sponsored K08 and K99/R00 grant in the current funding climate. Circ Res (2012) 1.47
Phosphorylation of phospholamban at threonine-17 reduces cardiac adrenergic contractile responsiveness in chronic pressure overload-induced hypertrophy. Am J Physiol Heart Circ Physiol (2006) 1.46
Modulation of contractility by myocyte-derived arginase in normal and hypertrophied feline myocardium. Am J Physiol Heart Circ Physiol (2005) 1.46
Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades. Mol Biol Cell (2007) 1.44
Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis. Ann Surg Oncol (2009) 1.43
Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice. J Clin Invest (2011) 1.41
Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation. J Clin Invest (2013) 1.40
NFATc3 regulates Kv2.1 expression in arterial smooth muscle. J Biol Chem (2004) 1.39
Calcium sparklets regulate local and global calcium in murine arterial smooth muscle. J Physiol (2006) 1.39
The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension. Proc Natl Acad Sci U S A (2008) 1.38
Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes. PLoS One (2009) 1.36
CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes. Circ Res (2009) 1.33
Bone-derived stem cells repair the heart after myocardial infarction through transdifferentiation and paracrine signaling mechanisms. Circ Res (2013) 1.33
Kv2 channels oppose myogenic constriction of rat cerebral arteries. Am J Physiol Cell Physiol (2006) 1.32
Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy. J Mol Cell Cardiol (2010) 1.31
Regulated overexpression of the A1-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function. Circulation (2006) 1.30
Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle. Am J Physiol Heart Circ Physiol (2007) 1.28
A homeobox protein, prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma. Clin Cancer Res (2006) 1.28
An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria. Proc Natl Acad Sci U S A (2011) 1.27
A caveolae-targeted L-type Ca²+ channel antagonist inhibits hypertrophic signaling without reducing cardiac contractility. Circ Res (2012) 1.26
Dynamic regulation of sodium/calcium exchange function in human heart failure. Circulation (2003) 1.24
Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis. Mol Cell Biol (2011) 1.24
Phenotypic differences in transient outward K+ current of human and canine ventricular myocytes: insights into molecular composition of ventricular Ito. Am J Physiol Heart Circ Physiol (2003) 1.22
Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling. Circ Res (2012) 1.20
Myostatin represses physiological hypertrophy of the heart and excitation-contraction coupling. J Physiol (2009) 1.19
Calcium entry via Na/Ca exchange during the action potential directly contributes to contraction of failing human ventricular myocytes. Cardiovasc Res (2003) 1.18