Published in Exp Cell Res on November 26, 2004
Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy. Curr Cancer Drug Targets (2008) 1.40
Analysis of CaM-kinase signaling in cells. Cell Calcium (2011) 1.30
Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy. Cancers (Basel) (2011) 1.25
c-FLIP, a master anti-apoptotic regulator. Exp Oncol (2012) 1.24
Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt. Pigment Cell Melanoma Res (2009) 1.19
Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression. Exp Cell Res (2007) 1.14
mTOR-independent translational control of the extrinsic cell death pathway by RalA. Mol Cell Biol (2006) 1.01
Expression of tumor necrosis factor--related apoptosis-inducing ligand receptors 1 and 2 in melanoma. Clin Cancer Res (2006) 1.01
Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma. Clin Cancer Res (2009) 1.01
alpha-CaMKII controls the growth of human osteosarcoma by regulating cell cycle progression. Lab Invest (2007) 0.95
Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression. Exp Cell Res (2006) 0.94
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. Mol Cancer Ther (2008) 0.94
Persistent reversal of enhanced amphetamine intake by transient CaMKII inhibition. J Neurosci (2013) 0.92
Sequential treatment by ionizing radiation and sodium arsenite dramatically accelerates TRAIL-mediated apoptosis of human melanoma cells. Cancer Res (2007) 0.91
The emerging role of CaMKII in cancer. Oncotarget (2015) 0.90
Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein. J Biol Chem (2013) 0.85
Doxorubicin and etoposide sensitize small cell lung carcinoma cells expressing caspase-8 to TRAIL. Mol Cancer (2010) 0.84
Fas Signaling Promotes Gastric Cancer Metastasis through STAT3-Dependent Upregulation of Fascin. PLoS One (2015) 0.78
Reticulon Protein-1C: A New Hope in the Treatment of Different Neuronal Diseases. Int J Cell Biol (2012) 0.75
POPX2 phosphatase regulates apoptosis through the TAK1-IKK-NF-κB pathway. Cell Death Dis (2017) 0.75
Memory Erasure Experiments Indicate a Critical Role of CaMKII in Memory Storage. Neuron (2017) 0.75
HMDB: the Human Metabolome Database. Nucleic Acids Res (2007) 13.38
HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res (2008) 11.23
Duration of red-cell storage and complications after cardiac surgery. N Engl J Med (2008) 10.04
Factors other than glomerular filtration rate affect serum cystatin C levels. Kidney Int (2008) 5.90
Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting. Crit Care Med (2006) 4.59
FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt. Cancer Cell (2009) 4.48
Global changes to the ubiquitin system in Huntington's disease. Nature (2007) 3.91
Neuronal CA2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function. Annu Rev Biochem (2001) 3.64
Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II. Biochem J (2002) 3.29
Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib. Cancer Cell (2012) 2.96
Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Autophagy (2011) 2.47
CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation. J Cell Biol (2005) 2.47
Transfusion in coronary artery bypass grafting is associated with reduced long-term survival. Ann Thorac Surg (2006) 2.42
Real-time magnetic resonance-guided stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy. Neurosurgery (2014) 2.41
CXCR4 is a major chemokine receptor on glioma cells and mediates their survival. J Biol Chem (2002) 2.37
Selective regulation of neurite extension and synapse formation by the beta but not the alpha isoform of CaMKII. Neuron (2003) 2.36
Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics. Lab Chip (2008) 2.11
Protein biomarker identification in the CSF of patients with CNS lymphoma. J Clin Oncol (2007) 2.07
Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B. J Neurosci (2006) 2.05
The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma. Mayo Clin Proc (2005) 2.00
The cardiac-specific nuclear delta(B) isoform of Ca2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. J Biol Chem (2001) 1.99
Perioperative management and treatment for complications during and after peroral endoscopic myotomy (POEM) for esophageal achalasia (EA) (data from 119 cases). Surg Endosc (2012) 1.98
The human cerebrospinal fluid metabolome. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 1.96
Identification of bacteria using tandem mass spectrometry combined with a proteome database and statistical scoring. Anal Chem (2004) 1.89
The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma. J Hepatol (2008) 1.88
SlipChip. Lab Chip (2009) 1.84
Persistent effect of red cell transfusion on health-related quality of life after cardiac surgery. Ann Thorac Surg (2006) 1.80
A mechanism for Ca2+/calmodulin-dependent protein kinase II clustering at synaptic and nonsynaptic sites based on self-association. J Neurosci (2005) 1.78
Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products. Cell Res (2010) 1.77
A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma. Cancer Discov (2012) 1.77
TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges. Rev Recent Clin Trials (2009) 1.73
Red cell transfusion is associated with an increased risk for postoperative atrial fibrillation. Ann Thorac Surg (2006) 1.71
Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation. PLoS One (2010) 1.70
Core/Shell semiconductor nanocrystals. Small (2009) 1.68
Protein standard absolute quantification (PSAQ) method for the measurement of cellular ubiquitin pools. Nat Methods (2011) 1.60
Risk of bone fractures associated with glucagon-like peptide-1 receptor agonists' treatment: a meta-analysis of randomized controlled trials. Endocrine (2014) 1.58
An ultrasensitive Ca2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling. Proc Natl Acad Sci U S A (2003) 1.57
Protein sequencing by mass analysis of polypeptide ladders after controlled protein hydrolysis. Nat Biotechnol (2004) 1.56
A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin- dependent kinase II holoenzyme. Cell (2011) 1.56
Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells. J Biol Chem (2002) 1.54
One-Step UV-Induced Synthesis of Polypyrrole/Ag Nanocomposites at the Water/Ionic Liquid Interface. Nanoscale Res Lett (2009) 1.50
Tactile, acoustic and vestibular systems sum to elicit the startle reflex. Neurosci Biobehav Rev (2002) 1.47
Deferasirox exposure induces reactive oxygen species and reduces growth and viability of myelodysplastic hematopoietic progenitors. Leuk Res (2012) 1.46
Three-layer reconstruction of large urethrocutaneous fistulas using scrotal-septal flaps. Can Urol Assoc J (2014) 1.45
Differential 12C-/13C-isotope dansylation labeling and fast liquid chromatography/mass spectrometry for absolute and relative quantification of the metabolome. Anal Chem (2009) 1.44
Regulation of calcium/calmodulin-dependent protein kinase II docking to N-methyl-D-aspartate receptors by calcium/calmodulin and alpha-actinin. J Biol Chem (2002) 1.44
Retrospective study of the incidence of HFMD and seroepidemiology of antibodies against EV71 and CoxA16 in prenatal women and their infants. PLoS One (2012) 1.44
Non-atherosclerotic fusiform cerebral aneurysms. Can J Neurol Sci (2002) 1.42
Validation of VKORC1 and CYP2C9 genotypes on interindividual warfarin maintenance dose: a prospective study in Chinese patients. Pharmacogenet Genomics (2009) 1.41
Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells. Blood (2005) 1.41
A few-view reweighted sparsity hunting (FRESH) method for CT image reconstruction. J Xray Sci Technol (2013) 1.40
Synthesis and cytotoxic activities of novel phenacylimidazolium bromides. Bioorg Med Chem Lett (2009) 1.36
Structural insights into the assembly and activation of IL-1β with its receptors. Nat Immunol (2010) 1.32
Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis. Ann Neurol (2012) 1.32
Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy. Clin Cancer Res (2011) 1.32
Lipid rafts and nonrafts mediate tumor necrosis factor related apoptosis-inducing ligand induced apoptotic and nonapoptotic signals in non small cell lung carcinoma cells. Cancer Res (2007) 1.31
Fabrication of high-quality In2Se3 nanowire arrays toward high-performance visible-light photodetectors. ACS Nano (2010) 1.31
Transfusion and pulmonary morbidity after cardiac surgery. Ann Thorac Surg (2009) 1.30
Chemical quenched flow kinetic studies indicate an intraholoenzyme autophosphorylation mechanism for Ca2+/calmodulin-dependent protein kinase II. J Biol Chem (2002) 1.30
Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation for lymphoma. J Clin Oncol (2009) 1.29
Performance of detecting IgM antibodies against enterovirus 71 for early diagnosis. PLoS One (2010) 1.28
A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma. Blood (2009) 1.28
Screening patients with diabetes mellitus for tuberculosis in China. Trop Med Int Health (2012) 1.27
A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Clin Cancer Res (2011) 1.26
Alternative splicing modulates the frequency-dependent response of CaMKII to Ca(2+) oscillations. EMBO J (2002) 1.23
China's first rare-disease registry is under development. Lancet (2011) 1.23
ERp19 and ERp46, new members of the thioredoxin family of endoplasmic reticulum proteins. Mol Cell Proteomics (2003) 1.22
Promiscuous protein biotinylation by Escherichia coli biotin protein ligase. Protein Sci (2004) 1.22
MiR-20a triggers metastasis of gallbladder carcinoma. J Hepatol (2013) 1.22
Interferon gamma induces neurite outgrowth by up-regulation of p35 neuron-specific cyclin-dependent kinase 5 activator via activation of ERK1/2 pathway. J Biol Chem (2005) 1.22
Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Nat Struct Mol Biol (2010) 1.21
Monocyte lipid rafts contain proteins implicated in vesicular trafficking and phagosome formation. Proteomics (2003) 1.21
Stable-isotope dimethylation labeling combined with LC-ESI MS for quantification of amine-containing metabolites in biological samples. Anal Chem (2007) 1.19
Differential dimethyl labeling of N-termini of peptides after guanidination for proteome analysis. J Proteome Res (2005) 1.19
Identification of mammalian proteins cross-linked to DNA by ionizing radiation. J Biol Chem (2005) 1.18
The protective role of hydrogen-rich saline in experimental liver injury in mice. J Hepatol (2010) 1.17
Chromatographic fingerprint analysis of Cephalotaxus sinensis from various sources by high-performance liquid chromatography-diodearray detection-electrospray ionization-tandem mass spectrometry. J Pharm Biomed Anal (2007) 1.17
Th1 and Th2 immune response in chronic hepatitis B patients during a long-term treatment with adefovir dipivoxil. Mediators Inflamm (2010) 1.17
Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis. J Biol Chem (2001) 1.16
Characteristics of embB mutations in multidrug-resistant Mycobacterium tuberculosis isolates in Henan, China. J Antimicrob Chemother (2011) 1.15
TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res (2004) 1.15
Local control of brain metastases by stereotactic radiosurgery in relation to dose to the tumor margin. J Neurosurg (2006) 1.15
Seroprevalence of avian influenza A (H5N1) virus among poultry workers in Jiangsu Province, China: an observational study. BMC Infect Dis (2012) 1.14
Palladium-catalyzed sequential arylation and allylic alkylation of highly functionalized ketones: a concise synthesis of mesembrine. Org Lett (2009) 1.14
Mitogen-activated protein kinase-dependent activation of the Na+/H+ exchanger is mediated through phosphorylation of amino acids Ser770 and Ser771. J Biol Chem (2007) 1.13
Embryonic stem cell markers. Molecules (2012) 1.13
Effect of functional health-related quality of life on long-term survival after cardiac surgery. Circulation (2007) 1.13
Gametophytic and zygotic selection leads to segregation distortion through in vivo induction of a maternal haploid in maize. J Exp Bot (2013) 1.12
Characterization of human tear proteome using multiple proteomic analysis techniques. J Proteome Res (2005) 1.11
Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. J Neurosci (2006) 1.11
Effects of common surfactants on protein digestion and matrix-assisted laser desorption/ionization mass spectrometric analysis of the digested peptides using two-layer sample preparation. Rapid Commun Mass Spectrom (2004) 1.11
TRAIL-induced apoptosis in human vascular endothelium is regulated by phosphatidylinositol 3-kinase/Akt through the short form of cellular FLIP and Bcl-2. J Vasc Res (2005) 1.10
The dentate gyrus neurogenesis: a therapeutic target for Alzheimer's disease. Acta Neuropathol (2002) 1.10
Single-crystalline Sb₂Se₃ nanowires for high-performance field emitters and photodetectors. Adv Mater (2010) 1.10
Size-tailored ZnO submicrometer spheres: bottom-up construction, size-related optical extinction, and selective aniline trapping. Adv Mater (2011) 1.10
Keratinocyte-releasable stratifin functions as a potent collagenase-stimulating factor in fibroblasts. J Invest Dermatol (2004) 1.10
Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment. Mol Cancer Ther (2011) 1.09