Published in Trends Endocrinol Metab on March 01, 2005
Small molecule mesengenic induction of human induced pluripotent stem cells to generate mesenchymal stem/stromal cells. Stem Cells Transl Med (2012) 1.41
FoxL2 and Smad3 coordinately regulate follistatin gene transcription. J Biol Chem (2008) 1.32
Paracrinicity: the story of 30 years of cellular pituitary crosstalk. J Neuroendocrinol (2008) 1.24
Activator protein-1 and smad proteins synergistically regulate human follicle-stimulating hormone beta-promoter activity. Endocrinology (2008) 1.19
ALK7 expression is specific for adipose tissue, reduced in obesity and correlates to factors implicated in metabolic disease. Biochem Biophys Res Commun (2009) 1.19
Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb. J Biol Chem (2010) 1.16
Activin signaling as an emerging target for therapeutic interventions. Cell Commun Signal (2009) 1.16
Cripto binds transforming growth factor beta (TGF-beta) and inhibits TGF-beta signaling. Mol Cell Biol (2006) 1.15
Growth factors and myometrium: biological effects in uterine fibroid and possible clinical implications. Hum Reprod Update (2011) 1.10
A novel role for the forkhead transcription factor FOXL2 in activin A-regulated follicle-stimulating hormone beta subunit transcription. Mol Endocrinol (2009) 1.08
Activin A circulating levels in patients with bone metastasis from breast or prostate cancer. Clin Exp Metastasis (2006) 1.06
Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease. J Exp Med (2009) 1.06
FoxL2 Is required for activin induction of the mouse and human follicle-stimulating hormone beta-subunit genes. Mol Endocrinol (2010) 1.03
Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction. J Cell Biol (2008) 1.01
Toxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signaling. J Biol Chem (2010) 0.98
GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cells. J Biol Chem (2008) 0.97
Caveolin-2 is a negative regulator of anti-proliferative function and signaling of transforming growth factor-β in endothelial cells. Am J Physiol Cell Physiol (2011) 0.92
Inhibin at 90: from discovery to clinical application, a historical review. Endocr Rev (2014) 0.91
Cripto/GRP78 modulation of the TGF-β pathway in development and oncogenesis. FEBS Lett (2012) 0.91
Hypoxia enhances the expression of follistatin-like 3 in term human trophoblasts. Placenta (2007) 0.88
Differential expression of follistatin and FLRG in human breast proliferative disorders. BMC Cancer (2009) 0.87
Identification of proteins involved in neural progenitor cell targeting of gliomas. BMC Cancer (2009) 0.87
Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells. Int J Cancer (2014) 0.87
Differential regulation of follicle stimulating hormone by activin A and TGFB1 in murine gonadotropes. Reprod Biol Endocrinol (2005) 0.87
PACAP, an autocrine/paracrine regulator of gonadotrophs. Biol Reprod (2010) 0.86
Bone morphogenetic protein 2 signals via BMPR1A to regulate murine follicle-stimulating hormone beta subunit transcription. Biol Reprod (2009) 0.85
Unique mutation portraits and frequent COL2A1 gene alteration in chondrosarcoma. Genome Res (2014) 0.85
Activin, neutrophils, and inflammation: just coincidence? Semin Immunopathol (2013) 0.85
Combinatory microarray and SuperSAGE analyses identify pairing-dependently transcribed genes in Schistosoma mansoni males, including follistatin. PLoS Negl Trop Dis (2013) 0.84
Peroxisome proliferator-activated receptor gamma down-regulates follistatin in intestinal epithelial cells through SP1. J Biol Chem (2008) 0.84
A high concentration of genistein down-regulates activin A, Smad3 and other TGF-β pathway genes in human uterine leiomyoma cells. Exp Mol Med (2012) 0.83
Methamphetamine-induced dopamine-independent alterations in striatal gene expression in the 6-hydroxydopamine hemiparkinsonian rats. PLoS One (2010) 0.83
Activins and follistatins: Emerging roles in liver physiology and cancer. World J Hepatol (2009) 0.82
Cell-type specific modulation of pituitary cells by activin, inhibin and follistatin. Mol Cell Endocrinol (2012) 0.81
Activin potentiates proliferation in mature avian auditory sensory epithelium. J Neurosci (2010) 0.81
Activin a inhibits antigen-induced allergy in murine epicutaneous sensitization. Front Immunol (2013) 0.80
Activin-A and myostatin response and steroid regulation in human myometrium: disruption of their signalling in uterine fibroid. J Clin Endocrinol Metab (2010) 0.80
The immunoregulatory and fibrotic roles of activin A in allergic asthma. Clin Exp Allergy (2015) 0.80
Expression of Nodal, Cripto, SMAD3, phosphorylated SMAD3, and SMAD4 in the proliferative endometrium of women with endometriosis. Reprod Sci (2014) 0.79
Serum from exercising humans suppresses t-cell cytokine production. Cytokine (2007) 0.79
Age and diet affect gene expression profiles in canine liver tissue. PLoS One (2010) 0.78
When the Smad signaling pathway is impaired, fibroblasts advance open wound contraction. Exp Mol Pathol (2010) 0.78
R7 photoreceptor axon growth is temporally controlled by the transcription factor Ttk69, which inhibits growth in part by promoting transforming growth factor-β/activin signaling. J Neurosci (2013) 0.77
Activin A prevents neuron-like PC12 cell apoptosis after oxygen-glucose deprivation. Neural Regen Res (2013) 0.76
N-terminal tyrosine phosphorylation of caveolin-2 negates anti-proliferative effect of transforming growth factor beta in endothelial cells. FEBS Lett (2012) 0.76
Activin A Stimulates Migration of the Fallopian Tube Epithelium, an Origin of High-Grade Serous Ovarian Cancer, through Non-Canonical Signaling. Cancer Lett (2017) 0.75
Prognostic value of follistatin-like 3 in human invasive breast cancer. Oncotarget (2017) 0.75
CRF and CRF receptors: role in stress responsivity and other behaviors. Annu Rev Pharmacol Toxicol (2004) 5.21
Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. Nature (2002) 3.67
The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. Dialogues Clin Neurosci (2006) 1.96
Structure of the ternary signaling complex of a TGF-beta superfamily member. Proc Natl Acad Sci U S A (2006) 1.88
The neurobiology of depression: inroads to treatment and new drug discovery. J Clin Psychiatry (2005) 1.81
NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor. Proc Natl Acad Sci U S A (2004) 1.80
International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands. Pharmacol Rev (2003) 1.79
Hormonal regulation of spermatogenesis in primates and man: insights for development of the male hormonal contraceptive. J Androl (2002) 1.76
GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth. Mol Cell Biol (2007) 1.64
Hormonal changes in the menopause transition. Recent Prog Horm Res (2002) 1.62
Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand. Proc Natl Acad Sci U S A (2007) 1.50
The relationship between the endocrine characteristics and the regularity of menstrual cycles in the approach to menopause. Menopause (2005) 1.47
Endocrine features of menstrual cycles in middle and late reproductive age and the menopausal transition classified according to the Staging of Reproductive Aging Workshop (STRAW) staging system. J Clin Endocrinol Metab (2007) 1.44
Ovarian status in healthy postmenopausal women: follow-up 12 months after transvaginal ultrasound. Menopause (2009) 1.42
Urocortin III-immunoreactive projections in rat brain: partial overlap with sites of type 2 corticotrophin-releasing factor receptor expression. J Neurosci (2002) 1.42
Selective activation of corticotropin-releasing factor-2 receptors on neurochemically identified neurons in the rat dorsal raphe nucleus reveals dual actions. J Neurosci (2004) 1.40
Increased depression-like behaviors in corticotropin-releasing factor receptor-2-deficient mice: sexually dichotomous responses. J Neurosci (2003) 1.39
Expression of urocortin peptides in canine myocardium and plasma. Vet J (2010) 1.37
Corticotropin-releasing factor receptor-2-deficient mice display abnormal homeostatic responses to challenges of increased dietary fat and cold. Endocrinology (2003) 1.34
FoxL2 and Smad3 coordinately regulate follistatin gene transcription. J Biol Chem (2008) 1.32
Menopause transition: Annual changes in serum hormonal patterns over the menstrual cycle in women during a nine-year period prior to menopause. J Clin Endocrinol Metab (2004) 1.29
Delayed satiety-like actions and altered feeding microstructure by a selective type 2 corticotropin-releasing factor agonist in rats: intra-hypothalamic urocortin 3 administration reduces food intake by prolonging the post-meal interval. Neuropsychopharmacology (2006) 1.27
Corticotropin-releasing factor receptors CRF1 and CRF2 exert both additive and opposing influences on defensive startle behavior. J Neurosci (2004) 1.26
Corticotropin-releasing factor and Urocortin I modulate excitatory glutamatergic synaptic transmission. J Neurosci (2004) 1.23
The cardiovascular physiologic actions of urocortin II: acute effects in murine heart failure. Proc Natl Acad Sci U S A (2004) 1.22
Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior. J Neurosci (2002) 1.19
Expression of nodal signalling components in cycling human endometrium and in endometrial cancer. Reprod Biol Endocrinol (2009) 1.18
Pituitary actions of ligands of the TGF-beta family: activins and inhibins. Reproduction (2006) 1.18
Chronic cocaine administration switches corticotropin-releasing factor2 receptor-mediated depression to facilitation of glutamatergic transmission in the lateral septum. J Neurosci (2005) 1.16
A complex containing alpha6beta1-integrin and phosphorylated focal adhesion kinase between Sertoli cells and elongated spermatids during spermatid release from the seminiferous epithelium. J Endocrinol (2006) 1.16
Effects of testosterone plus medroxyprogesterone acetate on semen quality, reproductive hormones, and germ cell populations in normal young men. J Clin Endocrinol Metab (2002) 1.15
Cycle and hormone changes during perimenopause: the key role of ovarian function. Menopause (2008) 1.14
Identification of distinct inhibin and transforming growth factor beta-binding sites on betaglycan: functional separation of betaglycan co-receptor actions. J Biol Chem (2006) 1.13
Locomotor suppressive and anxiolytic-like effects of urocortin 3, a highly selective type 2 corticotropin-releasing factor agonist. Brain Res (2003) 1.12
Atypical estradiol secretion and ovulation patterns caused by luteal out-of-phase (LOOP) events underlying irregular ovulatory menstrual cycles in the menopausal transition. Menopause (2009) 1.10
Growth factors and myometrium: biological effects in uterine fibroid and possible clinical implications. Hum Reprod Update (2011) 1.10
Cocaine withdrawal enhances long-term potentiation induced by corticotropin-releasing factor at central amygdala glutamatergic synapses via CRF, NMDA receptors and PKA. Eur J Neurosci (2006) 1.09
Autocrine/paracrine regulation of pituitary function by activin, inhibin and follistatin. Mol Cell Endocrinol (2004) 1.09
A soluble mouse brain splice variant of type 2alpha corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity. Proc Natl Acad Sci U S A (2005) 1.08
A soluble form of the first extracellular domain of mouse type 2beta corticotropin-releasing factor receptor reveals differential ligand specificity. J Biol Chem (2003) 1.06
Post-translational modifications and protein-specific isoforms in endometriosis revealed by 2D DIGE. J Proteome Res (2010) 1.05
Cripto is a noncompetitive activin antagonist that forms analogous signaling complexes with activin and nodal. J Biol Chem (2007) 1.05
Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation. Proc Natl Acad Sci U S A (2008) 1.05
CRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent manner. Proc Natl Acad Sci U S A (2009) 1.04
Ligand affinity for amino-terminal and juxtamembrane domains of the corticotropin releasing factor type I receptor: regulation by G-protein and nonpeptide antagonists. Biochemistry (2004) 1.04
An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors. J Biol Chem (2004) 1.04
Corticotropin-releasing factor receptor 2 is a tonic suppressor of vascularization. Proc Natl Acad Sci U S A (2002) 1.03
Common and divergent structural features of a series of corticotropin releasing factor-related peptides. J Am Chem Soc (2007) 1.02
Human urocortin II, a selective agonist for the type 2 corticotropin-releasing factor receptor, decreases feeding and drinking in the rat. J Pharmacol Exp Ther (2003) 1.01
Proteomic characterization of midproliferative and midsecretory human endometrium. J Proteome Res (2009) 1.01
Generation of a specific activin antagonist by modification of the activin A propeptide. Endocrinology (2011) 1.00
Two distinct regions of latency-associated peptide coordinate stability of the latent transforming growth factor-beta1 complex. J Biol Chem (2010) 0.99
Activin A and inhibin A differentially regulate human uterine matrix metalloproteinases: potential interactions during decidualization and trophoblast invasion. Endocrinology (2005) 0.98
Vital functions of corticotropin-releasing factor (CRF) pathways in maintenance and regulation of energy homeostasis. Proc Natl Acad Sci U S A (2006) 0.98
Human urocortin 2, a corticotropin-releasing factor (CRF)2 agonist, and ovine CRF, a CRF1 agonist, differentially alter feeding and motor activity. J Pharmacol Exp Ther (2004) 0.97
Photo-cross-linkers incorporated into G-protein-coupled receptors in mammalian cells: a ligand comparison. Angew Chem Int Ed Engl (2011) 0.97
NMR structure of the first extracellular domain of corticotropin-releasing factor receptor 1 (ECD1-CRF-R1) complexed with a high affinity agonist. J Biol Chem (2010) 0.97
Beneficial hemodynamic, endocrine, and renal effects of urocortin in experimental heart failure: comparison with normal sheep. J Am Coll Cardiol (2002) 0.96
A Smad-binding element in intron 1 participates in activin-dependent regulation of the follistatin gene. J Biol Chem (2008) 0.94
Proteomics of the human endometrium and uterine fluid: a pathway to biomarker discovery. Fertil Steril (2012) 0.94
Corticotropin-releasing factor receptor type 2 messenger ribonucleic acid in rat pituitary: localization and regulation by immune challenge, restraint stress, and glucocorticoids. Endocrinology (2003) 0.93
Cocaine- and amphetamine-regulated transcript activates the hypothalamic-pituitary-adrenal axis through a corticotropin-releasing factor receptor-dependent mechanism. Endocrinology (2004) 0.92
A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery. Proc Natl Acad Sci U S A (2010) 0.92
Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells. PLoS One (2012) 0.91
Structural basis of BMP signaling inhibition by Noggin, a novel twelve-membered cystine knot protein. J Bone Joint Surg Am (2003) 0.90
Modulation of activin and BMP signaling. Mol Cell Endocrinol (2004) 0.90
Suppression of inhibin A biological activity by alterations in the binding site for betaglycan. J Biol Chem (2008) 0.89
Activin-A binds follistatin and type II receptors through overlapping binding sites: generation of mutants with isolated binding activities. Endocrinology (2006) 0.89
Gonadotropins regulate rat testicular tight junctions in vivo. Endocrinology (2010) 0.88
The relative roles of follicle-stimulating hormone and luteinizing hormone in maintaining spermatogonial maturation and spermiation in normal men. J Clin Endocrinol Metab (2006) 0.87
A common biosynthetic pathway governs the dimerization and secretion of inhibin and related transforming growth factor beta (TGFbeta) ligands. J Biol Chem (2009) 0.87
Rat anterior pituitary folliculostellate cells are targets of interleukin-1beta and a major source of intrapituitary follistatin. Endocrinology (2003) 0.86
Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion. J Biol Chem (2013) 0.86
Cocaine- and amphetamine-regulated transcript is localized in pituitary lactotropes and is regulated during lactation. Endocrinology (2005) 0.86
Variability in sperm suppression during testosterone administration to adult monkeys is related to follicle stimulating hormone suppression and not to intratesticular androgens. J Clin Endocrinol Metab (2002) 0.85
The three-dimensional structure of the N-terminal domain of corticotropin-releasing factor receptors: sushi domains and the B1 family of G protein-coupled receptors. Ann N Y Acad Sci (2006) 0.85
A new role for corticotropin-releasing factor receptor-2: suppression of vascularization. Trends Cardiovasc Med (2003) 0.84
Glucocorticoids regulate the expression of the mouse urocortin II gene: a putative connection between the corticotropin-releasing factor receptor pathways. Mol Endocrinol (2003) 0.84
Regulation of corticotropin-releasing factor receptor type 2beta mRNA via cyclic AMP pathway in A7r5 aortic smooth muscle cells. Cell Signal (2003) 0.84
Distinct structural and functional roles of conserved residues in the first extracellular domain of receptors for corticotropin-releasing factor and related G-protein-coupled receptors. J Biol Chem (2007) 0.84
Immediate and sustained blood pressure lowering by urocortin 2: a novel approach to antihypertensive therapy? Hypertension (2009) 0.84
Relationship between serum gonadotropins and spermatogenic suppression in men undergoing steroidal contraceptive treatment. J Clin Endocrinol Metab (2004) 0.84
Inhibin A and B in vitro bioactivities are modified by their degree of glycosylation and their affinities to betaglycan. Endocrinology (2007) 0.84
Regulation of follicle-stimulating hormone secretion by the interactions of activin-A, dexamethasone and testosterone in anterior pituitary cell cultures of male rats. Neuroendocrinology (2003) 0.84
Identification of a functional binding site for activin on the type I receptor ALK4. J Biol Chem (2003) 0.83
The distribution of betaglycan protein and mRNA in rat brain, pituitary, and gonads: implications for a role for betaglycan in inhibin-mediated reproductive functions. Endocrinology (2002) 0.83
Designer nodal/BMP2 chimeras mimic nodal signaling, promote chondrogenesis, and reveal a BMP2-like structure. J Biol Chem (2013) 0.83
The role of corticotropin-releasing factor receptors in stress and anxiety. Integr Comp Biol (2002) 0.83
Chronic activation of corticotropin-releasing factor type 2 receptors reveals a key role for 5-HT1A receptor responsiveness in mediating behavioral and serotonergic responses to stressful challenge. Biol Psychiatry (2012) 0.83
An optimized procedure for the capture, fractionation and proteomic analysis of proteins using hydrogel nanoparticles. Proteomics (2010) 0.82
Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant. J Clin Endocrinol Metab (2002) 0.82
Acute effects of urocortin 2 on cardiac function and propensity for arrhythmias in an animal model of hypertension-induced left ventricular hypertrophy and heart failure. Eur J Heart Fail (2010) 0.82
Inhibin B is a more potent suppressor of rat follicle-stimulating hormone release than inhibin a in vitro and in vivo. Endocrinology (2009) 0.82
Cell-type specific modulation of pituitary cells by activin, inhibin and follistatin. Mol Cell Endocrinol (2012) 0.81
Activin-A and myostatin response and steroid regulation in human myometrium: disruption of their signalling in uterine fibroid. J Clin Endocrinol Metab (2010) 0.80
Feedback regulation by inhibins A and B of the pituitary secretion of follicle-stimulating hormone. Vitam Horm (2011) 0.79
Proteomic analysis of the intestinal adaptation response reveals altered expression of fatty acid binding proteins following massive small bowel resection. J Proteome Res (2010) 0.79
Rodent adrenocortical cells display high affinity binding sites and proteins for inhibin A, and express components required for autocrine signalling by activins and bone morphogenetic proteins. J Endocrinol (2006) 0.79