Published in Oncogene on May 05, 2005
MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition. J Exp Med (2012) 1.85
A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells. Nucleic Acids Res (2010) 1.13
Squelching glioblastoma stem cells by targeting REST for proteasomal degradation. Trends Neurosci (2009) 0.95
The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. PLoS One (2010) 0.92
The dark side of ZNF217, a key regulator of tumorigenesis with powerful biomarker value. Oncotarget (2015) 0.90
Elevated TRF2 in advanced breast cancers with short telomeres. Breast Cancer Res Treat (2010) 0.86
Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions. Nat Commun (2015) 0.83
DNA damage accumulation and TRF2 degradation in atypical Werner syndrome fibroblasts with LMNA mutations. Front Genet (2013) 0.81
Heregulin, a new regulator of telomere length in human cells. Oncotarget (2015) 0.77
Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeres. Cancer Cell Int (2011) 0.76
ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2. Oncotarget (2016) 0.75
Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood (2004) 7.21
Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J (2003) 5.61
In situ analyses of genome instability in breast cancer. Nat Genet (2004) 4.32
A versatile viral system for expression and depletion of proteins in mammalian cells. PLoS One (2009) 3.83
Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci U S A (2008) 2.99
Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells. PLoS One (2010) 2.55
Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells. Cancer Res (2009) 2.28
ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium. Proc Natl Acad Sci U S A (2012) 2.20
Recognition and processing of cisplatin- and oxaliplatin-DNA adducts. Crit Rev Oncol Hematol (2005) 2.16
Identification of genes directly regulated by the oncogene ZNF217 using chromatin immunoprecipitation (ChIP)-chip assays. J Biol Chem (2007) 1.88
MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition. J Exp Med (2012) 1.85
Exon-level microarray analyses identify alternative splicing programs in breast cancer. Mol Cancer Res (2010) 1.84
Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments. Integr Biol (Camb) (2008) 1.82
Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer. Cancer Res (2006) 1.69
Stepwise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization. Cancer Res (2009) 1.65
Cancer and aging: the importance of telomeres in genome maintenance. Int J Biochem Cell Biol (2005) 1.64
Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes. Cell Cycle (2009) 1.52
Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter. Mol Cell Biol (2005) 1.45
Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53. EMBO Mol Med (2012) 1.44
Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis. Cell Cycle (2007) 1.40
Human epithelial cell immortalization as a step in carcinogenesis. Cancer Lett (2003) 1.38
Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins. Mol Cell Biol (2006) 1.36
Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion. Oncogene (2002) 1.32
Molecular changes accompanying senescence and immortalization of cultured human mammary epithelial cells. Int J Biochem Cell Biol (2002) 1.32
Epigenetic regulation of normal human mammary cell type-specific miRNAs. Genome Res (2011) 1.27
Amplification of zinc finger gene 217 (ZNF217) and cancer: when good fingers go bad. Biochim Biophys Acta (2007) 1.27
ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction. Hum Mol Genet (2005) 1.25
Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized. Mol Cancer (2007) 1.24
DNA damage-induced phosphorylation of the human telomere-associated protein TRF2. Proc Natl Acad Sci U S A (2005) 1.24
The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines. Cancer Res (2010) 1.23
Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia. Cancer Res (2012) 1.20
Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanisms. PLoS One (2010) 1.19
p53-dependent integration of telomere and growth factor deprivation signals. Proc Natl Acad Sci U S A (2007) 1.18
miRNA gene promoters are frequent targets of aberrant DNA methylation in human breast cancer. PLoS One (2013) 1.17
Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo. Genes Dev (2010) 1.14
Shared environmental factors associated with telomere length maintenance in elderly male twins. Aging Cell (2007) 1.14
Loss of p53 function accelerates acquisition of telomerase activity in indefinite lifespan human mammary epithelial cell lines. Oncogene (2003) 1.13
Multidimensional profiling of cell surface proteins and nuclear markers. IEEE/ACM Trans Comput Biol Bioinform (2010) 1.13
Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cells. Proc Natl Acad Sci U S A (2011) 1.11
The specific role of pRb in p16 (INK4A) -mediated arrest of normal and malignant human breast cells. Cell Cycle (2012) 1.10
Primary cilium-dependent and -independent Hedgehog signaling inhibits p16(INK4A). Mol Cell (2010) 1.08
Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells. Cancer Res (2009) 1.08
The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression. Cancer Discov (2012) 1.06
Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. Cell Cycle (2014) 1.05
Aging and cancer cell biology, 2009. Aging Cell (2009) 1.04
Age-associated gene expression in normal breast tissue mirrors qualitative age-at-incidence patterns for breast cancer. Cancer Epidemiol Biomarkers Prev (2012) 1.03
Protein interactions with platinum-DNA adducts: from structure to function. J Inorg Biochem (2004) 1.00
The regulation of SOX7 and its tumor suppressive role in breast cancer. Am J Pathol (2013) 0.99
The luminal progenitor compartment of the normal human mammary gland constitutes a unique site of telomere dysfunction. Stem Cell Reports (2013) 0.99
DNA damage-induced phosphorylation of TRF2 is required for the fast pathway of DNA double-strand break repair. Mol Cell Biol (2009) 0.98
Telomere fusions in early human breast carcinoma. Proc Natl Acad Sci U S A (2012) 0.97
ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription. Mol Cancer Res (2006) 0.95
Processing of human reduction mammoplasty and mastectomy tissues for cell culture. J Vis Exp (2013) 0.92
Common chromosome fragile sites in human and murine epithelial cells and FHIT/FRA3B loss-induced global genome instability. Genes Chromosomes Cancer (2013) 0.92
Reconstructive surgery for lower pole ureteropelvic junction obstruction associated with incomplete ureteral duplication. J Pediatr Urol (2009) 0.91
Cellular senescence mediated by p16INK4A-coupled miRNA pathways. Nucleic Acids Res (2013) 0.90
Recruitment of TRF2 to laser-induced DNA damage sites. Free Radic Biol Med (2012) 0.89
Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies. Breast Cancer Res (2010) 0.88
p16(INK4a) -mediated suppression of telomerase in normal and malignant human breast cells. Aging Cell (2010) 0.88
Translesion synthesis past platinum DNA adducts by human DNA polymerase mu. Biochemistry (2003) 0.88
BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas. PLoS One (2010) 0.88
A novel yellowish-green fluorescent protein from the marine copepod, Chiridius poppei, and its use as a reporter protein in HeLa cells. Gene (2006) 0.88
Molecular cloning and expression of the hyu genes from Microbacterium liquefaciens AJ 3912, responsible for the conversion of 5-substituted hydantoins to alpha-amino acids, in Escherichia coli. Biosci Biotechnol Biochem (2005) 0.87
A hierarchy of endothelial colony-forming cell activity displayed by bovine corneal endothelial cells. Invest Ophthalmol Vis Sci (2010) 0.86
Effect of amplification of desensitized purF and prs on inosine accumulation in Escherichia coli. J Biosci Bioeng (2007) 0.86
Crystal structure of human calmodulin-like protein: insights into its functional role. FEBS Lett (2002) 0.85
Caspase-independent cytochrome c release is a sensitive measure of low-level apoptosis in cell culture models. Aging Cell (2005) 0.84
Who is in the driver's seat in 8p12 amplifications? ZNF703 in luminal B breast tumors. Breast Cancer Res (2011) 0.84
Soothing the watchman: telomerase reduces the p53-dependent cellular stress response. Cell Cycle (2007) 0.83
Karyotypic instability and centrosome aberrations in the progeny of finite life-span human mammary epithelial cells exposed to sparsely or densely ionizing radiation. Radiat Res (2008) 0.82
Cell-type specific DNA methylation patterns define human breast cellular identity. PLoS One (2012) 0.82
Inhibition of NF-κB and DNA double-strand break repair by DMAPT sensitizes non-small-cell lung cancers to X-rays. Free Radic Biol Med (2011) 0.81
Structural basis for red-shifted emission of a GFP-like protein from the marine copepod Chiridius poppei. Genes Cells (2009) 0.81
Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering. Genome Integr (2010) 0.80
A bioluminescent probe for salivary cortisol. Bioconjug Chem (2011) 0.78
Effects of edd and pgi disruptions on inosine accumulation in Escherichia coli. Biosci Biotechnol Biochem (2005) 0.78
An active C-terminally truncated form of Ca (2+) /calmodulin-dependent protein kinase phosphatase-N (CaMKP-N/PPM1E). Biomed Res Int (2013) 0.78
Effects of xapA and guaA disruption on inosine accumulation in Escherichia coli. Biosci Biotechnol Biochem (2006) 0.77
Improving protein secretion of a transglutaminase-secreting Corynebacterium glutamicum recombinant strain on the basis of 13C metabolic flux analysis. J Biosci Bioeng (2011) 0.76
Feminizing Adrenocortical Carcinoma with Distinct Histopathological Findings. Intern Med (2016) 0.75
Parabens and Human Epidermal Growth Factor Receptor Ligand Cross-Talk in Breast Cancer Cells. Environ Health Perspect (2015) 0.75
[Structure, application, and evolution of copepod luciferases]. Seikagaku (2015) 0.75
Chromatography of isoforms of recombinant apoaequorin and method for the preparation of aequorin. Protein Expr Purif (2003) 0.75