Published in IEEE/ACM Trans Comput Biol Bioinform on February 12, 2010
Morphometic analysis of TCGA glioblastoma multiforme. BMC Bioinformatics (2011) 1.26
Breast fibroblasts modulate early dissemination, tumorigenesis, and metastasis through alteration of extracellular matrix characteristics. Neoplasia (2013) 1.11
Iterative tensor voting for perceptual grouping of ill-defined curvilinear structures. IEEE Trans Med Imaging (2011) 0.97
Sparse multitask regression for identifying common mechanism of response to therapeutic targets. Bioinformatics (2010) 0.89
Effects of tissue decalcification on the quantification of breast cancer biomarkers by digital image analysis. Diagn Pathol (2014) 0.86
Molecular deconstruction, detection, and computational prediction of microenvironment-modulated cellular responses to cancer therapeutics. Adv Drug Deliv Rev (2014) 0.79
MORPHOMETRIC SUBTYPING FOR A PANEL OF BREAST CANCER CELL LINES. Proc IEEE Int Symp Biomed Imaging (2009) 0.78
Coupled Segmentation of Nuclear and Membrane-bound Macromolecules through Voting and Multiphase Level Set. Pattern Recognit (2015) 0.75
The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression. Mol Oncol (2007) 5.81
Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J (2003) 5.61
In situ analyses of genome instability in breast cancer. Nat Genet (2004) 4.32
A versatile viral system for expression and depletion of proteins in mammalian cells. PLoS One (2009) 3.83
Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts. J Natl Cancer Inst (2002) 3.39
Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition. Cancer Res (2009) 3.14
CD36 repression activates a multicellular stromal program shared by high mammographic density and tumor tissues. Cancer Discov (2012) 2.51
Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res (2004) 2.33
ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium. Proc Natl Acad Sci U S A (2012) 2.20
Iterative voting for inference of structural saliency and characterization of subcellular events. IEEE Trans Image Process (2007) 2.17
Identification of genes directly regulated by the oncogene ZNF217 using chromatin immunoprecipitation (ChIP)-chip assays. J Biol Chem (2007) 1.88
Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation. Am J Pathol (2002) 1.88
MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition. J Exp Med (2012) 1.85
Exon-level microarray analyses identify alternative splicing programs in breast cancer. Mol Cancer Res (2010) 1.84
Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors. Cancer Res (2004) 1.84
Establishing a nationwide emergency department-based syndromic surveillance system for better public health responses in Taiwan. BMC Public Health (2008) 1.81
TGF-beta biology in mammary development and breast cancer. Cold Spring Harb Perspect Biol (2011) 1.75
Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer. Cancer Res (2006) 1.69
Harmonic cut and regularized centroid transform for localization of subcellular structures. IEEE Trans Biomed Eng (2003) 1.69
Cancer and aging: the importance of telomeres in genome maintenance. Int J Biochem Cell Biol (2005) 1.64
Establishing a clinical decision rule of severe acute respiratory syndrome at the emergency department. Ann Emerg Med (2004) 1.61
Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition. Cancer Res (2007) 1.60
Intramuscular vascular endothelial growth factor gene therapy in patients with chronic critical leg ischemia. Am J Med (2003) 1.58
The molecular regulation of resistin expression in cultured vascular smooth muscle cells under hypoxia. J Hypertens (2008) 1.55
Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association. IEEE Trans Med Imaging (2012) 1.53
Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes. Cell Cycle (2009) 1.52
Isoform-specific activation of latent transforming growth factor beta (LTGF-beta) by reactive oxygen species. Radiat Res (2006) 1.47
Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture. PLoS Comput Biol (2010) 1.46
Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress. Cancer Res (2006) 1.42
Two Perspectives. Radiat Res (2015) 1.39
Human epithelial cell immortalization as a step in carcinogenesis. Cancer Lett (2003) 1.38
Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins. Mol Cell Biol (2006) 1.36
Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor-beta1 in adult mice. Am J Pathol (2005) 1.35
Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β. Cancer Res (2012) 1.34
Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion. Oncogene (2002) 1.32
TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo. Clin Cancer Res (2011) 1.30
Amplification of zinc finger gene 217 (ZNF217) and cancer: when good fingers go bad. Biochim Biophys Acta (2007) 1.27
Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains. PLoS Comput Biol (2007) 1.26
Morphometic analysis of TCGA glioblastoma multiforme. BMC Bioinformatics (2011) 1.26
ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction. Hum Mol Genet (2005) 1.25
Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type. Cancer Cell (2011) 1.25
COMPARISON OF SPARSE CODING AND KERNEL METHODS FOR HISTOPATHOLOGICAL CLASSIFICATION OF GLIOBASTOMA MULTIFORME. Proc IEEE Int Symp Biomed Imaging (2011) 1.24
Transforming growth factor-beta1 mediates cellular response to DNA damage in situ. Cancer Res (2002) 1.23
Carvedilol prevents cardiac hypertrophy and overexpression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in pressure-overloaded rat heart. J Biomed Sci (2005) 1.22
Intramyocardial injection of naked DNA encoding HIF-1alpha/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat. Cardiovasc Res (2002) 1.20
p53-dependent integration of telomere and growth factor deprivation signals. Proc Natl Acad Sci U S A (2007) 1.18
Imaging features that discriminate between foci induced by high- and low-LET radiation in human fibroblasts. Radiat Res (2006) 1.16
Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo. Genes Dev (2010) 1.14
Loss of p53 function accelerates acquisition of telomerase activity in indefinite lifespan human mammary epithelial cell lines. Oncogene (2003) 1.13
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. PLoS Biol (2011) 1.12
Breast fibroblasts modulate early dissemination, tumorigenesis, and metastasis through alteration of extracellular matrix characteristics. Neoplasia (2013) 1.11
The specific role of pRb in p16 (INK4A) -mediated arrest of normal and malignant human breast cells. Cell Cycle (2012) 1.10
Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells. Cancer Res (2009) 1.08
New rationales for using TGFbeta inhibitors in radiotherapy. Int J Radiat Biol (2007) 1.07
Classification of Tumor Histology via Morphometric Context. Proc IEEE Comput Soc Conf Comput Vis Pattern Recognit (2013) 1.07
The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression. Cancer Discov (2012) 1.06
Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors. Stem Cells (2014) 1.05
Multireference level set for the characterization of nuclear morphology in glioblastoma multiforme. IEEE Trans Biomed Eng (2012) 1.05
Mechanical stretch enhances the expression of resistin gene in cultured cardiomyocytes via tumor necrosis factor-alpha. Am J Physiol Heart Circ Physiol (2007) 1.04
Aging and cancer cell biology, 2009. Aging Cell (2009) 1.04
Age-associated gene expression in normal breast tissue mirrors qualitative age-at-incidence patterns for breast cancer. Cancer Epidemiol Biomarkers Prev (2012) 1.03
Classification of Histology Sections via Multispectral Convolutional Sparse Coding. Conf Comput Vis Pattern Recognit Workshops (2014) 1.02
Graphical methods for quantifying macromolecules through bright field imaging. Bioinformatics (2008) 1.02
Angiotensin II signals mechanical stretch-induced cardiac matrix metalloproteinase expression via JAK-STAT pathway. J Mol Cell Cardiol (2004) 1.01
Mapping mammary gland architecture using multi-scale in situ analysis. Integr Biol (Camb) (2008) 1.00
Ionizing radiation induces heritable disruption of epithelial cell interactions. Proc Natl Acad Sci U S A (2003) 0.99
Surgical adverse outcomes in patients with schizophrenia: a population-based study. Ann Surg (2013) 0.98
Iterative tensor voting for perceptual grouping of ill-defined curvilinear structures. IEEE Trans Med Imaging (2011) 0.97
Synergistic effect of angiopoietin-1 and vascular endothelial growth factor on neoangiogenesis in hypercholesterolemic rabbit model with acute hindlimb ischemia. Life Sci (2003) 0.96
Targeted and nontargeted effects of ionizing radiation that impact genomic instability. Cancer Res (2008) 0.96
Linking changes in epithelial morphogenesis to cancer mutations using computational modeling. PLoS Comput Biol (2010) 0.96
The not-so innocent bystander: the microenvironment as a therapeutic target in cancer. Expert Opin Ther Targets (2003) 0.96
Prediction of epigenetically regulated genes in breast cancer cell lines. BMC Bioinformatics (2010) 0.95
CLASSIFICATION OF TUMOR HISTOPATHOLOGY VIA SPARSE FEATURE LEARNING. Proc IEEE Int Symp Biomed Imaging (2013) 0.95
Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-alpha in cultured human umbilical vein endothelial cells. Cardiovasc Res (2003) 0.95
Segmentation of heterogeneous blob objects through voting and level set formulation. Pattern Recognit Lett (2007) 0.95
Mechanical stretch induces the apoptosis regulator PUMA in vascular smooth muscle cells. Cardiovasc Res (2011) 0.94
Integrated profiling of three dimensional cell culture models and 3D microscopy. Bioinformatics (2013) 0.93
Angiotensin II activates myostatin expression in cultured rat neonatal cardiomyocytes via p38 MAP kinase and myocyte enhance factor 2 pathway. J Endocrinol (2008) 0.93
Carvedilol modulates the expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in a rat model of volume-overload heart failure. J Card Fail (2005) 0.90
Mechanical stretch via transforming growth factor-β1 activates microRNA208a to regulate endoglin expression in cultured rat cardiac myoblasts. Eur J Heart Fail (2012) 0.90
Quantitative in vivo microscopy: the return from the 'omics'. Curr Opin Biotechnol (2006) 0.90
Accumulation and altered localization of telomere-associated protein TRF2 in immortally transformed and tumor-derived human breast cells. Oncogene (2005) 0.89
Sparse multitask regression for identifying common mechanism of response to therapeutic targets. Bioinformatics (2010) 0.89
System for combined three-dimensional morphological and molecular analysis of thick tissue specimens. Microsc Res Tech (2002) 0.89
Increased expression of angiopoietin-2 and Tie2 receptor in a rat model of myocardial ischaemia/reperfusion. Clin Sci (Lond) (2003) 0.88
Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ions. Int J Radiat Biol (2011) 0.88
p16(INK4a) -mediated suppression of telomerase in normal and malignant human breast cells. Aging Cell (2010) 0.88
Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies. Breast Cancer Res (2010) 0.88