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1
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A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells.
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Nat Cell Biol
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2004
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6.61
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2
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From promiscuity to precision: protein phosphatases get a makeover.
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Mol Cell
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2009
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4.17
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3
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Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia.
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Nat Struct Mol Biol
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2007
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2.76
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4
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Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2.
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Mol Cell Biol
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2003
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2.70
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5
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Induction of spine growth and synapse formation by regulation of the spine actin cytoskeleton.
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Neuron
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2004
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2.68
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6
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The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases.
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Annu Rev Physiol
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2006
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2.18
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7
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Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis.
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Cell
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2006
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2.15
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8
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Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets.
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J Biol Chem
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2007
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1.59
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9
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Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1.
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J Clin Invest
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2007
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1.57
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10
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PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation.
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EMBO J
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2003
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1.50
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11
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Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases.
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J Biol Chem
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2003
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1.50
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12
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Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
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Am J Physiol Cell Physiol
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2003
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1.35
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13
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Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation.
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Mol Biol Cell
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2005
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1.34
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14
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Defective parathyroid hormone regulation of NHE3 activity and phosphate adaptation in cultured NHERF-1-/- renal proximal tubule cells.
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J Biol Chem
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2004
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1.29
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15
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Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology.
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Mol Cell Biol
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2002
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1.29
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16
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Adenoviral expression of NHERF-1 in NHERF-1 null mouse renal proximal tubule cells restores Npt2a regulation by low phosphate media and parathyroid hormone.
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Am J Physiol Renal Physiol
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2006
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1.18
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17
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Defective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media.
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Am J Physiol Renal Physiol
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2005
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1.18
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18
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Protein serine/threonine phosphatases in neuronal plasticity and disorders of learning and memory.
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Trends Neurosci
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2006
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1.17
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19
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NHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranes.
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FEBS Lett
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2003
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1.16
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20
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Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton.
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J Biol Chem
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2002
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1.14
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21
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Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice.
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J Biol Chem
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2007
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1.11
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22
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NHERF-1 is required for renal adaptation to a low-phosphate diet.
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Am J Physiol Renal Physiol
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2003
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1.10
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23
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Signaling pathways utilized by PTH and dopamine to inhibit phosphate transport in mouse renal proximal tubule cells.
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Am J Physiol Renal Physiol
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2008
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1.10
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24
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Control of cellular GADD34 levels by the 26S proteasome.
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Mol Cell Biol
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2008
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1.09
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25
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The role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a.
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J Physiol
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2005
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1.08
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26
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The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits.
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J Biol Chem
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2002
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1.07
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27
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A C-terminal PDZ motif in NHE3 binds NHERF-1 and enhances cAMP inhibition of sodium-hydrogen exchange.
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Biochemistry
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2003
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1.04
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28
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Sodium-hydrogen exchanger regulatory factor 1 (NHERF-1) transduces signals that mediate dopamine inhibition of sodium-phosphate co-transport in mouse kidney.
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J Biol Chem
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2010
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1.01
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29
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Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice.
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Am J Physiol Cell Physiol
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2006
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1.01
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30
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Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport.
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J Biol Chem
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2010
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0.99
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31
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Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport.
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J Am Soc Nephrol
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2007
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0.98
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32
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NHERF and regulation of the renal sodium-hydrogen exchanger NHE3.
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Pflugers Arch
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2005
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0.97
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33
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PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP.
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Am J Physiol Renal Physiol
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2009
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0.97
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34
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Phosphorylation of phosphatase inhibitor-2 at centrosomes during mitosis.
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J Biol Chem
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2003
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0.97
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35
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Longitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null mice.
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Am J Physiol Renal Physiol
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2005
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0.96
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36
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Increased renal dopamine and acute renal adaptation to a high-phosphate diet.
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Am J Physiol Renal Physiol
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2011
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0.94
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37
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Targeting phosphorylation of eukaryotic initiation factor-2α to treat human disease.
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Prog Mol Biol Transl Sci
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2012
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0.91
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Fibroblast growth factor-23-mediated inhibition of renal phosphate transport in mice requires sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) and synergizes with parathyroid hormone.
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J Biol Chem
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2011
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0.90
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39
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Protein phosphatases mediate depotentiation induced by high-intensity theta-burst stimulation.
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J Neurophysiol
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2003
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0.89
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40
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Association with endoplasmic reticulum promotes proteasomal degradation of GADD34 protein.
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J Biol Chem
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2011
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0.89
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41
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Dynamics of PTH-induced disassembly of Npt2a/NHERF-1 complexes in living OK cells.
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Am J Physiol Renal Physiol
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2010
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0.87
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42
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Expression of human protein phosphatase-1 in Saccharomyces cerevisiae highlights the role of phosphatase isoforms in regulating eukaryotic functions.
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J Biol Chem
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2007
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The inhibitor-1 C terminus facilitates hormonal regulation of cellular protein phosphatase-1: functional implications for inhibitor-1 isoforms.
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J Biol Chem
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2004
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Role of NHERF and scaffolding proteins in proximal tubule transport.
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Urol Res
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2010
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Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice.
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Am J Physiol Renal Physiol
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2008
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Use of protein phosphatase inhibitors.
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Curr Protoc Protein Sci
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2003
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Use of protein phosphatase inhibitors.
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Curr Protoc Mol Biol
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2003
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0.81
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Importance of a surface hydrophobic pocket on protein phosphatase-1 catalytic subunit in recognizing cellular regulators.
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J Biol Chem
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2005
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0.80
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Phosphorylation at tyrosine 262 promotes GADD34 protein turnover.
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J Biol Chem
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2013
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Identification of cellular protein phosphatase-1 regulators.
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Methods Mol Biol
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Next-generation sequencing of apoptotic DNA breakpoints reveals association with actively transcribed genes and gene translocations.
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PLoS One
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2011
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Dangerous liaisons: flirtations between oncogenic BRAF and GRP78 in drug-resistant melanomas.
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J Clin Invest
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Reversible protein phosphorylation. Preface.
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Prog Mol Biol Transl Sci
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2012
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