Published in J Clin Invest on November 01, 2007
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NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains. Mol Biol Cell (2012) 0.84
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PTH-mediated inhibition of the renal transport of phosphate. Exp Cell Res (2012) 0.77
Roles for NHERF1 and NHERF2 on the regulation of C3a receptor signaling in human mast cells. PLoS One (2012) 0.77
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NaPi-IIa interacting proteins and regulation of renal reabsorption of phosphate. Urol Res (2010) 0.77
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The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells. Mol Biol Cell (2007) 1.53
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The NHE3 juxtamembrane cytoplasmic domain directly binds ezrin: dual role in NHE3 trafficking and mobility in the brush border. Mol Biol Cell (2006) 1.34
A kinase-regulated mechanism controls CFTR channel gating by disrupting bivalent PDZ domain interactions. Proc Natl Acad Sci U S A (2003) 1.31
Defective parathyroid hormone regulation of NHE3 activity and phosphate adaptation in cultured NHERF-1-/- renal proximal tubule cells. J Biol Chem (2004) 1.29
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Adenoviral expression of NHERF-1 in NHERF-1 null mouse renal proximal tubule cells restores Npt2a regulation by low phosphate media and parathyroid hormone. Am J Physiol Renal Physiol (2006) 1.18
Defective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media. Am J Physiol Renal Physiol (2005) 1.18
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Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport. J Am Soc Nephrol (2007) 0.98
The opossum kidney cell type IIa Na/P(i) cotransporter is a phosphoprotein. Kidney Blood Press Res (2001) 0.87
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From promiscuity to precision: protein phosphatases get a makeover. Mol Cell (2009) 4.17
Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia. Nat Struct Mol Biol (2007) 2.76
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol Cell Biol (2003) 2.70
Induction of spine growth and synapse formation by regulation of the spine actin cytoskeleton. Neuron (2004) 2.68
The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases. Annu Rev Physiol (2006) 2.18
Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis. Cell (2006) 2.15
Structural and biochemical bases for the inhibition of autophagy and apoptosis by viral BCL-2 of murine gamma-herpesvirus 68. PLoS Pathog (2008) 2.09
A ketogenic diet rescues the murine succinic semialdehyde dehydrogenase deficient phenotype. Exp Neurol (2007) 1.82
Regulation of ion transport by the NHERF family of PDZ proteins. Physiology (Bethesda) (2004) 1.74
Arthritis suppressor genes TIA-1 and TTP dampen the expression of tumor necrosis factor alpha, cyclooxygenase 2, and inflammatory arthritis. Proc Natl Acad Sci U S A (2004) 1.71
The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover. Mol Biol Cell (2010) 1.65
Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets. J Biol Chem (2007) 1.59
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Mechanistic coupling of bacteriophage T4 DNA packaging to components of the replication-dependent late transcription machinery. J Biol Chem (2006) 1.41
Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse. Am J Physiol Cell Physiol (2003) 1.35
Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation. Mol Biol Cell (2005) 1.34
Defective parathyroid hormone regulation of NHE3 activity and phosphate adaptation in cultured NHERF-1-/- renal proximal tubule cells. J Biol Chem (2004) 1.29
Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology. Mol Cell Biol (2002) 1.29
Adenoviral expression of NHERF-1 in NHERF-1 null mouse renal proximal tubule cells restores Npt2a regulation by low phosphate media and parathyroid hormone. Am J Physiol Renal Physiol (2006) 1.18
Defective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media. Am J Physiol Renal Physiol (2005) 1.18
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NHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranes. FEBS Lett (2003) 1.16
Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton. J Biol Chem (2002) 1.14
Downregulation of autophagy by herpesvirus Bcl-2 homologs. Autophagy (2007) 1.12
Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice. J Biol Chem (2007) 1.11
NHERF-1 is required for renal adaptation to a low-phosphate diet. Am J Physiol Renal Physiol (2003) 1.10
Signaling pathways utilized by PTH and dopamine to inhibit phosphate transport in mouse renal proximal tubule cells. Am J Physiol Renal Physiol (2008) 1.10
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The role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a. J Physiol (2005) 1.08
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A C-terminal PDZ motif in NHE3 binds NHERF-1 and enhances cAMP inhibition of sodium-hydrogen exchange. Biochemistry (2003) 1.04
Sodium-hydrogen exchanger regulatory factor 1 (NHERF-1) transduces signals that mediate dopamine inhibition of sodium-phosphate co-transport in mouse kidney. J Biol Chem (2010) 1.01
Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice. Am J Physiol Cell Physiol (2006) 1.01
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Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport. J Biol Chem (2010) 0.99
Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport. J Am Soc Nephrol (2007) 0.98
NHERF and regulation of the renal sodium-hydrogen exchanger NHE3. Pflugers Arch (2005) 0.97
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PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP. Am J Physiol Renal Physiol (2009) 0.97
Parathyroid hormone regulation of NA+,K+-ATPase requires the PDZ 1 domain of sodium hydrogen exchanger regulatory factor-1 in opossum kidney cells. J Am Soc Nephrol (2005) 0.96
Longitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null mice. Am J Physiol Renal Physiol (2005) 0.96
Increased renal dopamine and acute renal adaptation to a high-phosphate diet. Am J Physiol Renal Physiol (2011) 0.94
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Fibroblast growth factor-23-mediated inhibition of renal phosphate transport in mice requires sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) and synergizes with parathyroid hormone. J Biol Chem (2011) 0.90
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Role of NHERF and scaffolding proteins in proximal tubule transport. Urol Res (2010) 0.83
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Phosphorylation at tyrosine 262 promotes GADD34 protein turnover. J Biol Chem (2013) 0.79
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