Published in J Exp Med on March 14, 2005
Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns. Nat Rev Immunol (2010) 4.06
B-cell responses to vaccination at the extremes of age. Nat Rev Immunol (2009) 2.50
A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells. Immunity (2016) 1.79
Strategies for selective priming of memory B cells. Immunol Lett (2007) 1.47
Evolution of the immune system in humans from infancy to old age. Proc Biol Sci (2015) 1.31
Affinity of antigen encounter and other early B-cell signals determine B-cell fate. Curr Opin Immunol (2007) 1.11
Defective B-cell response to T-dependent immunization in lupus-prone mice. Eur J Immunol (2008) 0.88
Increased IL-12 inhibits B cells' differentiation to germinal center cells and promotes differentiation to short-lived plasmablasts. J Exp Med (2008) 0.88
Plasma cell homeostasis: the effects of chronic antigen stimulation and inflammation. J Immunol (2013) 0.87
Role of complement receptor type 2 and endogenous complement in the humoral immune response to conjugates of complement C3d and pneumococcal serotype 14 capsular polysaccharide. Infect Immun (2005) 0.83
Uncoupling CD21 and CD19 of the B-cell coreceptor. Proc Natl Acad Sci U S A (2009) 0.82
Low-affinity B cells transport viral particles from the lung to the spleen to initiate antibody responses. Proc Natl Acad Sci U S A (2012) 0.81
B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-alphaGAL-producing B-1 cells. Blood (2006) 0.79
Mesenchymal stem cells infected with Mycoplasma arginini secrete complement C3 to regulate immunoglobulin production in B lymphocytes. Cell Death Dis (2014) 0.77
Distinct T helper cell dependence of memory B cell proliferation versus plasma cell differentiation. Immunology (2016) 0.75
Antigen-induced B cell apoptosis is independent of complement C4. Clin Exp Immunol (2007) 0.75
Germinal centers. Annu Rev Immunol (1994) 10.85
Immunological memory and protective immunity: understanding their relation. Science (1996) 10.02
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell (1993) 9.84
Plasma cell differentiation requires the transcription factor XBP-1. Nature (2001) 9.72
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol (2003) 7.06
Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. Immunity (2003) 5.95
A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells. J Immunol Methods (1983) 4.39
The follicular dendritic cell: its role in antigen presentation in the generation of immunological memory. Immunol Rev (1980) 3.53
Generation of memory B cells and plasma cells in vitro. Science (1995) 3.45
Bone marrow is a major site of long-term antibody production after acute viral infection. J Virol (1995) 3.32
The influence of antigen organization on B cell responsiveness. Science (1993) 3.32
Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers. Science (1996) 3.24
On immunological memory. Annu Rev Immunol (1996) 3.21
A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells. Blood (2000) 3.13
The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response. EMBO J (1997) 3.09
Neutralizing antiviral B cell responses. Annu Rev Immunol (1997) 2.86
Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2. Proc Natl Acad Sci U S A (1996) 2.71
Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo. J Immunol (2000) 2.67
The CD19/CR2/TAPA-1 complex of B lymphocytes: linking natural to acquired immunity. Annu Rev Immunol (1995) 2.64
Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection. Nat Med (2002) 2.54
Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen. Immunity (1996) 2.29
Long-lived plasma cells: a mechanism for maintaining persistent antibody production. Curr Opin Immunol (1998) 2.10
Expression of complement receptors 1 and 2 on follicular dendritic cells is necessary for the generation of a strong antigen-specific IgG response. J Immunol (1998) 1.96
Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex. Annu Rev Immunol (2000) 1.95
Protective T cell-independent antiviral antibody responses are dependent on complement. J Exp Med (1999) 1.79
bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells. J Exp Med (2000) 1.76
Short-lived and long-lived bone marrow plasma cells are derived from a novel precursor population. J Exp Med (2002) 1.63
Suppression of the immune response by a soluble complement receptor of B lymphocytes. Science (1991) 1.63
Dual antigen recognition by B cells. Immunol Today (1993) 1.60
Dependence of germinal center B cells on expression of CD21/CD35 for survival. Science (1998) 1.59
Antigen-specific B cell memory: expression and replenishment of a novel b220(-) memory b cell compartment. J Exp Med (2000) 1.58
Antibody response to a T-dependent antigen requires B cell expression of complement receptors. J Exp Med (1996) 1.52
Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses. Immunity (2002) 1.50
Regulation of IgG antibody responses by epitope density and CD21-mediated costimulation. Eur J Immunol (2002) 1.39
Differentiation of early plasma cells on bone marrow stromal cells requires interleukin-6 for escaping from apoptosis. Blood (1995) 1.36
B lymphocyte memory: role of stromal cell complement and FcgammaRIIB receptors. J Exp Med (2002) 1.32
IL-10 interrupts memory B cell expansion in the germinal center by inducing differentiation into plasma cells. Eur J Immunol (1998) 1.24
T cell-independent type I antibody response against B cell epitopes expressed repetitively on recombinant virus particles. Proc Natl Acad Sci U S A (1998) 1.24
Immune responses in the absence of costimulation: viruses know the trick. J Immunol (1998) 1.23
Transcriptional regulatory cascades controlling plasma cell differentiation. Immunol Rev (2003) 1.19
How many specific B cells are needed to protect against a virus? J Immunol (1994) 1.15
Humoral immune responses in Cr2-/- mice: enhanced affinity maturation but impaired antibody persistence. J Immunol (2000) 1.14
Rapid response of marginal zone B cells to viral particles. J Immunol (2004) 1.13
The rise and fall of long-lived humoral immunity: terminal differentiation of plasma cells in health and disease. Immunol Rev (2003) 1.13
Recombinant RNA phage Q beta capsid particles synthesized and self-assembled in Escherichia coli. Gene (1993) 1.13
Impaired affinity maturation in Cr2-/- mice is rescued by adjuvants without improvement in germinal center development. J Immunol (2000) 1.07
Development and maintenance of a B220- memory B cell compartment. J Immunol (2001) 1.06
Nucleotide sequence of a ssRNA phage from Acinetobacter: kinship to coliphages. J Gen Virol (2002) 1.05
Antiviral B cell memory in the absence of mature follicular dendritic cell networks and classical germinal centers in TNFR1-/- mice. J Immunol (2000) 1.03
The distinct roles of T cell-derived cytokines and a novel follicular dendritic cell-signaling molecule 8D6 in germinal center-B cell differentiation. J Immunol (2001) 1.00
Mutilation of RNA phage Qbeta virus-like particles: from icosahedrons to rods. FEBS Lett (2000) 0.93
Cutting edge: recruitment of the CD19/CD21 coreceptor to B cell antigen receptor is required for antigen-mediated expression of Bcl-2 by resting and cycling hen egg lysozyme transgenic B cells. J Immunol (1999) 0.90
Ligation of CD27 on B cells in vivo during primary immunization enhances commitment to memory B cell responses. J Immunol (2003) 0.85
Regulation of humoral immune responses by CD21/CD35. Immunol Rev (2000) 0.81
mTOR regulates memory CD8 T-cell differentiation. Nature (2009) 10.07
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell (2008) 6.37
IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur J Immunol (2007) 4.54
IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science (2009) 3.90
Interleukin-1 is responsible for acute lung immunopathology but increases survival of respiratory influenza virus infection. J Virol (2005) 3.14
Nanoparticles target distinct dendritic cell populations according to their size. Eur J Immunol (2008) 2.97
Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens. Proc Natl Acad Sci U S A (2002) 2.95
Malarial hemozoin is a Nalp3 inflammasome activating danger signal. PLoS One (2009) 2.93
Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity. Immunity (2011) 2.87
Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study. Lancet (2008) 2.77
Regulation of homeostatic chemokine expression and cell trafficking during immune responses. Science (2007) 2.67
A lymphotoxin-driven pathway to hepatocellular carcinoma. Cancer Cell (2009) 2.64
Influenza A vaccine based on the extracellular domain of M2: weak protection mediated via antibody-dependent NK cell activity. J Immunol (2004) 2.59
IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo. Eur J Immunol (2008) 2.58
Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection. Nat Med (2002) 2.54
The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3. J Virol (2004) 2.11
TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses. J Immunol (2007) 2.11
A vaccine against nicotine for smoking cessation: a randomized controlled trial. PLoS One (2008) 2.07
Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity. Nat Med (2003) 2.04
Estimating animal population density using passive acoustics. Biol Rev Camb Philos Soc (2012) 2.02
GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survival. J Exp Med (2008) 1.99
TLR9 signaling in B cells determines class switch recombination to IgG2a. J Immunol (2007) 1.95
Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: antibodies provide the key. Eur J Immunol (2004) 1.94
Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses. J Exp Med (2004) 1.88
The coming of age of virus-like particle vaccines. Biol Chem (2008) 1.85
Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis. Eur J Immunol (2006) 1.84
A therapeutic vaccine for nicotine dependence: preclinical efficacy, and Phase I safety and immunogenicity. Eur J Immunol (2005) 1.84
Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors. J Exp Med (2007) 1.82
IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo. Blood (2006) 1.79
Neutralization of IL-17 by active vaccination inhibits IL-23-dependent autoimmune myocarditis. Eur J Immunol (2006) 1.75
IL-6 is required for glioma development in a mouse model. Oncogene (2004) 1.74
Nonmethylated CG motifs packaged into virus-like particles induce protective cytotoxic T cell responses in the absence of systemic side effects. J Immunol (2004) 1.74
CD80+Gr-1+ myeloid cells inhibit development of antifungal Th1 immunity in mice with candidiasis. J Immunol (2002) 1.73
Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response. Immunity (2011) 1.70
A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity. J Hypertens (2007) 1.68
CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells. Immunity (2005) 1.63
Cutting edge: identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1. J Immunol (2006) 1.59
Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk. J Clin Invest (2012) 1.58
CD40-CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells. Proc Natl Acad Sci U S A (2009) 1.56
VSIG4, a B7 family-related protein, is a negative regulator of T cell activation. J Clin Invest (2006) 1.51
Bacterial-induced protection against allergic inflammation through a multicomponent immunoregulatory mechanism. Thorax (2011) 1.49
IL-17-producing T cells in lung immunity and inflammation. J Allergy Clin Immunol (2009) 1.48
A molecular assembly system that renders antigens of choice highly repetitive for induction of protective B cell responses. Vaccine (2002) 1.48
Activation of dendritic cells through the interleukin 1 receptor 1 is critical for the induction of autoimmune myocarditis. J Exp Med (2003) 1.46
SCART scavenger receptors identify a novel subset of adult gammadelta T cells. J Immunol (2008) 1.45
Distinct roles for IL-6 and IL-12p40 in mediating protection against Leishmania donovani and the expansion of IL-10+ CD4+ T cells. Eur J Immunol (2006) 1.44
Regulation of IgG antibody responses by epitope density and CD21-mediated costimulation. Eur J Immunol (2002) 1.39
Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6. Proc Natl Acad Sci U S A (2006) 1.39
Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis. Eur J Immunol (2011) 1.37
Averting inflammation by targeting the cytokine environment. Nat Rev Drug Discov (2010) 1.36
Dyslipidemia inhibits Toll-like receptor-induced activation of CD8alpha-negative dendritic cells and protective Th1 type immunity. J Exp Med (2007) 1.36
Fatty acid-induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis. Nat Immunol (2013) 1.36
Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo. Immunity (2008) 1.34
Lymph node resident rather than skin-derived dendritic cells initiate specific T cell responses after Leishmania major infection. J Immunol (2006) 1.34
Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression. Proc Natl Acad Sci U S A (2011) 1.33
The IL-1 receptor 1 is critical for Th2 cell type airway immune responses in a mild but not in a more severe asthma model. Eur J Immunol (2003) 1.33
Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner. J Immunol (2010) 1.32
Efficient induction of mucosal and systemic immune responses by virus-like particles administered intranasally: implications for vaccine design. Eur J Immunol (2008) 1.30
Interleukin-6-deficient mice resist development of autoimmune myocarditis associated with impaired upregulation of complement C3. Circulation (2003) 1.29
Role of Toll-like receptors in costimulating cytotoxic T cell responses. Eur J Immunol (2003) 1.26
Chemokines: more than just road signs. Nat Rev Immunol (2006) 1.24
Cutting edge: LPS-induced emergency myelopoiesis depends on TLR4-expressing nonhematopoietic cells. J Immunol (2012) 1.23
Nippostrongylus brasiliensis infection leads to the development of emphysema associated with the induction of alternatively activated macrophages. Eur J Immunol (2008) 1.22
Innate signals compensate for the absence of PKC-{theta} during in vivo CD8(+) T cell effector and memory responses. Proc Natl Acad Sci U S A (2005) 1.21
T-cell fate and function: PKC-theta and beyond. Trends Immunol (2008) 1.17
Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis. J Cell Biol (2010) 1.14
Isolation of human monoclonal antibodies by mammalian cell display. Proc Natl Acad Sci U S A (2008) 1.14
A virus-like particle-based vaccine selectively targeting soluble TNF-alpha protects from arthritis without inducing reactivation of latent tuberculosis. J Immunol (2007) 1.13
Rapid response of marginal zone B cells to viral particles. J Immunol (2004) 1.13
Role of interleukin-1 in prion disease-associated astrocyte activation. Am J Pathol (2004) 1.13
Regulation of memory antibody levels: the role of persisting antigen versus plasma cell life span. J Immunol (2007) 1.12
Lack of IL-6 augments inflammatory response but decreases vascular permeability in bacterial meningitis. Brain (2003) 1.12
Versatile virus-like particle carrier for epitope based vaccines. PLoS One (2010) 1.12
Der p 1 peptide on virus-like particles is safe and highly immunogenic in healthy adults. J Allergy Clin Immunol (2006) 1.11
Mechanisms of allergen-specific desensitization. J Allergy Clin Immunol (2010) 1.11
Vaccination against nicotine: an emerging therapy for tobacco dependence. Expert Opin Investig Drugs (2007) 1.11
Aberrant acute-phase response in aged interleukin-6 knockout mice. Shock (2006) 1.11
A method for detecting whistles, moans, and other frequency contour sounds. J Acoust Soc Am (2011) 1.11
IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis. Blood (2012) 1.10
Critical role for activation of antigen-presenting cells in priming of cytotoxic T cell responses after vaccination with virus-like particles. J Immunol (2002) 1.10
TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signaling and promote autoimmune myocarditis. J Immunol (2007) 1.10
Universal vaccine against influenza virus: linking TLR signaling to anti-viral protection. Eur J Immunol (2012) 1.09
Innate immunity together with duration of antigen persistence regulate effector T cell induction. J Immunol (2003) 1.09
Innate immunity mediates follicular transport of particulate but not soluble protein antigen. J Immunol (2012) 1.09