Published in Genes Cells on April 01, 2005
Endoplasmic reticulum architecture: structures in flux. Curr Opin Cell Biol (2006) 1.75
VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death. J Biol Chem (2009) 1.31
GNOM-LIKE1/ERMO1 and SEC24a/ERMO2 are required for maintenance of endoplasmic reticulum morphology in Arabidopsis thaliana. Plant Cell (2009) 1.02
Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exit. J Cell Biol (2008) 0.97
Topology of molecular machines of the endoplasmic reticulum: a compilation of proteomics and cytological data. Histochem Cell Biol (2008) 0.84
From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation. J Biomed Sci (2012) 0.80
A resealed-cell system for analyzing pathogenic intracellular events: perturbation of endocytic pathways under diabetic conditions. PLoS One (2012) 0.77
VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation. Nat Commun (2016) 0.76
Asymmetrical diacylglycerol dynamics on the cytosolic and lumenal sides of a single endomembrane in living cells. Sci Rep (2015) 0.75
Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα. PLoS Pathog (2017) 0.75
A Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase. Front Mol Biosci (2017) 0.75
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature (2006) 24.39
The role of autophagy during the early neonatal starvation period. Nature (2004) 22.40
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell (2003) 17.55
Autophagy defends cells against invading group A Streptococcus. Science (2004) 9.53
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev (2004) 9.24
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J Cell Sci (2004) 9.20
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation. Nat Cell Biol (2009) 7.84
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci (2003) 6.50
A time-dependent phase shift in the mammalian unfolded protein response. Dev Cell (2003) 4.99
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure. Nature (2012) 4.46
Autophagosomes form at ER-mitochondria contact sites. Nature (2013) 4.32
Subcellular localization of Toll-like receptor 3 in human dendritic cells. J Immunol (2003) 4.22
An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure. Mol Biol Cell (2008) 4.00
Autophagy is essential for preimplantation development of mouse embryos. Science (2008) 3.55
EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin. Science (2003) 3.28
ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER. Science (2008) 3.18
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J Cell Biol (2009) 2.83
Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells. Cancer Res (2004) 2.78
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. J Cell Biol (2006) 2.76
Identification of a vesicular nucleotide transporter. Proc Natl Acad Sci U S A (2008) 2.53
Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state. Nat Cell Biol (2006) 2.37
Preoperative gemcitabine-based chemoradiation therapy for resectable and borderline resectable pancreatic cancer. Ann Surg (2013) 2.17
Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRDeltaF508. Mol Biol Cell (2008) 2.14
Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. Mol Biol Cell (2008) 2.08
VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo. J Cell Biol (2002) 2.06
Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development. PLoS One (2011) 2.01
The crystal structure of murine p97/VCP at 3.6A. J Struct Biol (2003) 1.98
Novel regulation of MHC class II function in B cells. EMBO J (2007) 1.98
GFP-like proteins stably accumulate in lysosomes. Cell Struct Funct (2008) 1.97
p37 is a p97 adaptor required for Golgi and ER biogenesis in interphase and at the end of mitosis. Dev Cell (2006) 1.95
EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming. J Biol Chem (2006) 1.91
From lysosomes to the plasma membrane: localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiation. J Biol Chem (2003) 1.91
Enhancement of endoplasmic reticulum (ER) degradation of misfolded Null Hong Kong alpha1-antitrypsin by human ER mannosidase I. J Biol Chem (2003) 1.86
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells. J Cell Biol (2008) 1.85
Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi. EMBO J (2004) 1.82
Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP. J Biol Chem (2008) 1.77
Type I collagen in Hsp47-null cells is aggregated in endoplasmic reticulum and deficient in N-propeptide processing and fibrillogenesis. Mol Biol Cell (2006) 1.77
Biochemical characterization of the prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B complex. J Biol Chem (2009) 1.74
Organelle degradation during the lens and erythroid differentiation is independent of autophagy. Biochem Biophys Res Commun (2005) 1.73
Myotubularin regulates the function of the late endosome through the gram domain-phosphatidylinositol 3,5-bisphosphate interaction. J Biol Chem (2004) 1.73
Helicobacter pylori infection increases the risk of colorectal adenoma and adenocarcinoma, especially in women. J Gastroenterol (2005) 1.71
The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells. J Cell Sci (2006) 1.68
Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47. EMBO J (2004) 1.68
Bap31 is an itinerant protein that moves between the peripheral endoplasmic reticulum (ER) and a juxtanuclear compartment related to ER-associated Degradation. Mol Biol Cell (2008) 1.66
Raloxifene hydrochloride is an adjuvant antiviral treatment of postmenopausal women with chronic hepatitis C: a randomized trial. J Hepatol (2012) 1.62
SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation. Cell Struct Funct (2002) 1.58
The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens. J Biol Chem (2008) 1.57
The phospholipase D1 pathway modulates macroautophagy. Nat Commun (2010) 1.56
Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection. Mol Biol Cell (2009) 1.55
Mouse Tudor Repeat-1 (MTR-1) is a novel component of chromatoid bodies/nuages in male germ cells and forms a complex with snRNPs. Mech Dev (2003) 1.54
Live cell imaging and electron microscopy reveal dynamic processes of BAF-directed nuclear envelope assembly. J Cell Sci (2008) 1.53
Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes. BMC Biol (2009) 1.51
Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice. J Biol Chem (2003) 1.51
Conformational changes in the AAA ATPase p97-p47 adaptor complex. EMBO J (2006) 1.48
Mechanism and components of endoplasmic reticulum-associated degradation. J Biochem (2009) 1.48
Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans. J Biol Chem (2009) 1.47
An initial step of GAS-containing autophagosome-like vacuoles formation requires Rab7. PLoS Pathog (2009) 1.43
EGF signalling amplification induced by dynamic clustering of EGFR. Biochem Biophys Res Commun (2004) 1.39
A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes. Traffic (2006) 1.38
Analysis of knock-out mice to determine the role of HPC-1/syntaxin 1A in expressing synaptic plasticity. J Neurosci (2006) 1.37
ARMET is a soluble ER protein induced by the unfolded protein response via ERSE-II element. Cell Struct Funct (2007) 1.37
Motions and negative cooperativity between p97 domains revealed by cryo-electron microscopy and quantised elastic deformational model. J Mol Biol (2003) 1.36
Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase. J Biol Chem (2008) 1.36
Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy. Cancer Res (2005) 1.35
Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5. Mol Cell (2011) 1.33
Identification of PCBP2, a facilitator of IRES-mediated translation, as a novel constituent of stress granules and processing bodies. RNA (2008) 1.33
Protein folding and quality control in the ER. Cold Spring Harb Perspect Biol (2011) 1.33
The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells. Genes Cells (2004) 1.32
Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain. Eur J Neurosci (2005) 1.32
Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury. EMBO J (2013) 1.31
Phosphorylation of nephrin triggers its internalization by raft-mediated endocytosis. J Am Soc Nephrol (2009) 1.30
The localization and phosphorylation of p47 are important for Golgi disassembly-assembly during the cell cycle. J Cell Biol (2003) 1.29
Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum. Mol Biol Cell (2004) 1.29
Synaptotagmin VII is targeted to dense-core vesicles and regulates their Ca2+ -dependent exocytosis in PC12 cells. J Biol Chem (2004) 1.29
Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection. Proc Natl Acad Sci U S A (2012) 1.28
Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion. EMBO J (2004) 1.28
Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis. PLoS One (2013) 1.28
The cytoplasmic 'linker region' in Toll-like receptor 3 controls receptor localization and signaling. Int Immunol (2004) 1.28
Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3. Autophagy (2008) 1.27
Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis. J Biol Chem (2002) 1.25
EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded alpha1-antitrypsin. Genes Cells (2006) 1.25
Crucial role for autophagy in degranulation of mast cells. J Allergy Clin Immunol (2011) 1.23
p125 is localized in endoplasmic reticulum exit sites and involved in their organization. J Biol Chem (2004) 1.22
p97/p47-Mediated biogenesis of Golgi and ER. J Biochem (2005) 1.21
Characterization of multiple members of the HSP70 family in platyfish culture cells: molecular evolution of stress protein HSP70 in vertebrates. Gene (2004) 1.21
Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers glutamatergic signal transmission in islets of Langerhans. J Biol Chem (2002) 1.20
Cytosolic chaperonin protects folding intermediates of Gbeta from aggregation by recognizing hydrophobic beta-strands. Proc Natl Acad Sci U S A (2006) 1.20
Pivotal role of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and autophagy. J Biol Chem (2007) 1.20
Human ABCA3, a product of a responsible gene for abca3 for fatal surfactant deficiency in newborns, exhibits unique ATP hydrolysis activity and generates intracellular multilamellar vesicles. Biochem Biophys Res Commun (2004) 1.20