Published in Development on March 30, 2005
Preparing for the first breath: genetic and cellular mechanisms in lung development. Dev Cell (2010) 4.78
Lung organogenesis. Curr Top Dev Biol (2010) 2.30
Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci (2010) 2.07
An FGF-WNT gene regulatory network controls lung mesenchyme development. Dev Biol (2008) 1.78
Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development. Dev Biol (2007) 1.74
Mesenchymal cells. Defining a mesenchymal progenitor niche at single-cell resolution. Science (2014) 1.73
FGF9 and SHH regulate mesenchymal Vegfa expression and development of the pulmonary capillary network. Development (2007) 1.67
Mammary gland development. Wiley Interdiscip Rev Dev Biol (2013) 1.64
Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling. PLoS One (2008) 1.63
Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol (2010) 1.59
Stem/progenitor cells in lung development, injury repair, and regeneration. Proc Am Thorac Soc (2008) 1.45
Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury. J Clin Invest (2011) 1.38
Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease. Proc Am Thorac Soc (2009) 1.38
FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis. BMC Dev Biol (2005) 1.27
FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia. BMC Dev Biol (2008) 1.26
Wnt2 signaling is necessary and sufficient to activate the airway smooth muscle program in the lung by regulating myocardin/Mrtf-B and Fgf10 expression. Dev Biol (2011) 1.19
Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors. Development (2013) 1.17
Fgf10-expressing tanycytes add new neurons to the appetite/energy-balance regulating centers of the postnatal and adult hypothalamus. J Neurosci (2013) 1.17
Tracheal occlusion increases the rate of epithelial branching of embryonic mouse lung via the FGF10-FGFR2b-Sprouty2 pathway. Mech Dev (2007) 1.13
Impact of the loss of Hoxa5 function on lung alveogenesis. Am J Pathol (2006) 1.12
Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung. Dev Dyn (2009) 1.11
Endogenous and exogenous stem cells: a role in lung repair and use in airway tissue engineering and transplantation. J Biomed Sci (2010) 1.11
Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling. Pulm Circ (2013) 1.09
Wnt signaling in lung organogenesis. Organogenesis (2008) 1.06
Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors. Development (2010) 1.06
Mesodermal deletion of transforming growth factor-beta receptor II disrupts lung epithelial morphogenesis: cross-talk between TGF-beta and Sonic hedgehog pathways. J Biol Chem (2008) 1.03
Fgf10-positive cells represent a progenitor cell population during lung development and postnatally. Development (2013) 1.02
miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development. Development (2014) 1.01
FGF10/FGFR2b signaling is essential for cardiac fibroblast development and growth of the myocardium. Development (2011) 1.00
The control of branching morphogenesis. Open Biol (2013) 1.00
Fibroblast growth factor 9 signaling inhibits airway smooth muscle differentiation in mouse lung. Dev Dyn (2009) 0.97
Signaling networks regulating development of the lower respiratory tract. Cold Spring Harb Perspect Biol (2012) 0.97
A role for mesenchyme dynamics in mouse lung branching morphogenesis. PLoS One (2012) 0.93
Activation of the canonical bone morphogenetic protein (BMP) pathway during lung morphogenesis and adult lung tissue repair. PLoS One (2012) 0.93
Characterization of a novel fibroblast growth factor 10 (Fgf10) knock-in mouse line to target mesenchymal progenitors during embryonic development. PLoS One (2012) 0.92
Progenitors of secondary crest myofibroblasts are developmentally committed in early lung mesoderm. Stem Cells (2015) 0.90
The pulmonary mesenchyme directs lung development. Curr Opin Genet Dev (2015) 0.90
Prenatal retinoid deficiency leads to airway hyperresponsiveness in adult mice. J Clin Invest (2014) 0.89
Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol (2011) 0.89
Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways. Proc Natl Acad Sci U S A (2013) 0.88
Lung stem and progenitor cells in tissue homeostasis and disease. Curr Top Dev Biol (2014) 0.87
Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype. J Clin Invest (2012) 0.87
ABCG2pos lung mesenchymal stem cells are a novel pericyte subpopulation that contributes to fibrotic remodeling. Am J Physiol Cell Physiol (2014) 0.87
A breath of fresh air on the mesenchyme: impact of impaired mesenchymal development on the pathogenesis of bronchopulmonary dysplasia. Front Med (Lausanne) (2015) 0.85
Identification and characterization of mouse otic sensory lineage genes. Front Cell Neurosci (2015) 0.84
Lung epithelial stem cells and their niches: Fgf10 takes center stage. Fibrogenesis Tissue Repair (2014) 0.84
Embryological origin of airway smooth muscle. Proc Am Thorac Soc (2008) 0.84
Stem cells in airway smooth muscle: state of the art. Proc Am Thorac Soc (2008) 0.83
Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation? BMC Dev Biol (2011) 0.82
Localized Smooth Muscle Differentiation Is Essential for Epithelial Bifurcation during Branching Morphogenesis of the Mammalian Lung. Dev Cell (2015) 0.82
Wnt and FGF mediated epithelial-mesenchymal crosstalk during lung development. Dev Dyn (2014) 0.82
FGF-Regulated ETV Transcription Factors Control FGF-SHH Feedback Loop in Lung Branching. Dev Cell (2015) 0.81
Fibroblast growth factor 10 alters the balance between goblet and Paneth cells in the adult mouse small intestine. Am J Physiol Gastrointest Liver Physiol (2015) 0.81
Walking along the Fibroblast Growth Factor 10 Route: A Key Pathway to Understand the Control and Regulation of Epithelial and Mesenchymal Cell-Lineage Formation during Lung Development and Repair after Injury. Scientifica (Cairo) (2014) 0.81
Simulations demonstrate a simple network to be sufficient to control branch point selection, smooth muscle and vasculature formation during lung branching morphogenesis. Biol Open (2012) 0.81
Neuron-derived FGF10 ameliorates cerebral ischemia injury via inhibiting NF-κB-dependent neuroinflammation and activating PI3K/Akt survival signaling pathway in mice. Sci Rep (2016) 0.80
Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis. PLoS One (2012) 0.80
Cell-based therapy in lung regenerative medicine. Regen Med Res (2014) 0.80
Comparative molecular developmental aspects of the mammalian- and the avian lungs, and the insectan tracheal system by branching morphogenesis: recent advances and future directions. Front Zool (2012) 0.79
c-Myc regulates proliferation and Fgf10 expression in airway smooth muscle after airway epithelial injury in mouse. PLoS One (2013) 0.79
Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development. Development (2015) 0.78
Centrifugal migration of mesenchymal cells in embryonic lung. Dev Dyn (2008) 0.78
Uterine epithelial cell proliferation and endometrial hyperplasia: evidence from a mouse model. Mol Hum Reprod (2014) 0.78
Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol (2016) 0.77
Exploiting mechanical stimuli to rescue growth of the hypoplastic lung. Pediatr Surg Int (2007) 0.77
Fluid mechanics as a driver of tissue-scale mechanical signaling in organogenesis. Curr Pathobiol Rep (2016) 0.75
Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6. Cell (2017) 0.75
Follistatin like-1 (Fstl1) is required for the normal formation of lung airway and vascular smooth muscle at birth. PLoS One (2017) 0.75
Protein interaction mapping: a Drosophila case study. Genome Res (2005) 4.15
Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42. J Cell Biol (2004) 3.06
Epithelial-mesenchymal transitions: insights from development. Development (2012) 2.58
Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells. Nat Cell Biol (2008) 2.46
Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clin Exp Metastasis (2007) 2.41
Regional copy number-independent deregulation of transcription in cancer. Nat Genet (2006) 2.33
Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin. J Cell Biol (2006) 2.32
Lung organogenesis. Curr Top Dev Biol (2010) 2.30
Host microenvironment in breast cancer development: epithelial-mesenchymal transition in breast cancer development. Breast Cancer Res (2003) 2.30
Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung. Dev Biol (2005) 2.23
Johnson-Kendall-Roberts theory applied to living cells. Phys Rev Lett (2005) 2.13
Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates. Dev Cell (2009) 2.10
Epithelial to mesenchymal transition and breast cancer. Breast Cancer Res (2009) 2.05
Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo. Development (2002) 1.99
Molecular mechanisms of early lung specification and branching morphogenesis. Pediatr Res (2005) 1.97
Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease. Thorax (2012) 1.88
Mouse embryonic mammogenesis as a model for the molecular regulation of pattern formation. Differentiation (2003) 1.85
Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development. Dev Biol (2007) 1.74
Activating mutations of the tyrosine kinase receptor FGFR3 are associated with benign skin tumors in mice and humans. Hum Mol Genet (2005) 1.74
Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice. Cardiovasc Res (2006) 1.73
Wnt5a regulates Shh and Fgf10 signaling during lung development. Dev Biol (2005) 1.66
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol (2009) 1.65
Differential role of FGF9 on epithelium and mesenchyme in mouse embryonic lung. Dev Biol (2006) 1.64
Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol (2010) 1.59
Isolation of mouse mammary epithelial progenitor cells with basal characteristics from the Comma-Dbeta cell line. Dev Biol (2006) 1.59
Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia. Development (2004) 1.58
The human tissue plasminogen activator-Cre mouse: a new tool for targeting specifically neural crest cells and their derivatives in vivo. Dev Biol (2003) 1.56
miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol (2009) 1.56
Oncogenic properties of the mutated forms of fibroblast growth factor receptor 3b. Carcinogenesis (2005) 1.54
Identification of a proliferation gene cluster associated with HPV E6/E7 expression level and viral DNA load in invasive cervical carcinoma. Oncogene (2005) 1.50
Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes. Development (2006) 1.49
Insights into plant biomass conversion from the genome of the anaerobic thermophilic bacterium Caldicellulosiruptor bescii DSM 6725. Nucleic Acids Res (2011) 1.48
Lung development and adult lung diseases. Chest (2007) 1.47
Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages. Stem Cells (2008) 1.46
Stem/progenitor cells in lung development, injury repair, and regeneration. Proc Am Thorac Soc (2008) 1.45
Identification of the mammary line in mouse by Wnt10b expression. Dev Dyn (2004) 1.40
Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype. Mol Cell Biol (2004) 1.39
Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury. J Clin Invest (2011) 1.38
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer. EMBO Mol Med (2013) 1.38
The physiology and pathology of the EMT. Meeting on the epithelial-mesenchymal transition. EMBO Rep (2008) 1.36
Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis. Cancer Res (2013) 1.36
Integrins in mammary gland development and differentiation of mammary epithelium. J Mammary Gland Biol Neoplasia (2003) 1.30
Disseminated tumor cells of breast cancer patients: a strong prognostic factor for distant and local relapse. Clin Cancer Res (2008) 1.30
Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via beta-catenin activation. Hepatology (2007) 1.30
SnapShot: The epithelial-mesenchymal transition. Cell (2011) 1.28
Colonic atresia without mesenteric vascular occlusion. The role of the fibroblast growth factor 10 signaling pathway. J Pediatr Surg (2005) 1.28
Early events in cell adhesion and polarity during epithelial-mesenchymal transition. J Cell Sci (2012) 1.27
FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis. BMC Dev Biol (2005) 1.27
Atrial myocardium derives from the posterior region of the second heart field, which acquires left-right identity as Pitx2c is expressed. Development (2008) 1.26
Next stop, the twilight zone: hedgehog network regulation of mammary gland development. J Mammary Gland Biol Neoplasia (2004) 1.20
Growth factor signaling in lung morphogenetic centers: automaticity, stereotypy and symmetry. Respir Res (2003) 1.20
Prototypical type I E-cadherin and type II cadherin-7 mediate very distinct adhesiveness through their extracellular domains. J Biol Chem (2005) 1.20
Contrasting expression of canonical Wnt signaling reporters TOPGAL, BATGAL and Axin2(LacZ) during murine lung development and repair. PLoS One (2011) 1.20
The importance of being a myoepithelial cell. Breast Cancer Res (2002) 1.20
Screening therapeutic EMT blocking agents in a three-dimensional microenvironment. Integr Biol (Camb) (2013) 1.17
Fgf10-expressing tanycytes add new neurons to the appetite/energy-balance regulating centers of the postnatal and adult hypothalamus. J Neurosci (2013) 1.17
Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. Dev Biol (2006) 1.15
Lung development and susceptibility to chronic obstructive pulmonary disease. Proc Am Thorac Soc (2006) 1.15
Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury. Am J Respir Crit Care Med (2009) 1.15
α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength. J Biol Chem (2012) 1.14
Tracheal occlusion increases the rate of epithelial branching of embryonic mouse lung via the FGF10-FGFR2b-Sprouty2 pathway. Mech Dev (2007) 1.13
Fibroblast growth factor receptor 2 IIIb invalidation--a potential cause of familial duodenal atresia. J Pediatr Surg (2004) 1.11
Dermal fin rays and scales derive from mesoderm, not neural crest. Curr Biol (2013) 1.11
Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia. Am J Respir Crit Care Med (2010) 1.10
Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling. Gastroenterology (2006) 1.08
The anti-scar effects of basic fibroblast growth factor on the wound repair in vitro and in vivo. PLoS One (2013) 1.08
Signaling via Alk5 controls the ontogeny of lung Clara cells. Development (2010) 1.07
Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors. Development (2010) 1.06
Mammary glands and feathers: comparing two skin appendages which help define novel classes during vertebrate evolution. Semin Cell Dev Biol (2007) 1.06
A cell-based small molecule screening method for identifying inhibitors of epithelial-mesenchymal transition in carcinoma. PLoS One (2012) 1.06
Visualizing chromosomes as transcriptome correlation maps: evidence of chromosomal domains containing co-expressed genes--a study of 130 invasive ductal breast carcinomas. Cancer Res (2005) 1.05
Separation force measurements reveal different types of modulation of E-cadherin-based adhesion by nectin-1 and -3. J Biol Chem (2004) 1.05
Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development (2011) 1.04
FGF10 controls the patterning of the tracheal cartilage rings via Shh. Development (2010) 1.03
Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation. Hum Mol Genet (2010) 1.03
The fibroblast growth factor pathway serves a regulatory role in proliferation and apoptosis in the pathogenesis of intestinal atresia. J Pediatr Surg (2006) 1.03
EGF controls the in vivo developmental potential of a mammary epithelial cell line possessing progenitor properties. J Cell Biol (2002) 1.03
Targeting pathways contributing to epithelial-mesenchymal transition (EMT) in epithelial ovarian cancer. Curr Drug Targets (2012) 1.03
Fgf10-positive cells represent a progenitor cell population during lung development and postnatally. Development (2013) 1.02
Clinical and biological characteristics of cervical neoplasias with FGFR3 mutation. Mol Cancer (2005) 1.02
SMAD3 prevents binding of NKX2.1 and FOXA1 to the SpB promoter through its MH1 and MH2 domains. Nucleic Acids Res (2007) 1.02
Target cell movement in tumor and cardiovascular diseases based on the epithelial-mesenchymal transition concept. Adv Drug Deliv Rev (2011) 1.01
miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development. Development (2014) 1.01
Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Respir Crit Care Med (2009) 1.01
The secretion and uptake of lysosomal phospholipase A2 by alveolar macrophages. J Immunol (2008) 1.00
YY1 regulates the neural crest-associated slug gene in Xenopus laevis. J Biol Chem (2004) 1.00