Published in Cancer Res on April 15, 2005
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer (2006) 8.50
Mitochondrial DNA repair in aging and disease. Mech Ageing Dev (2008) 1.43
Mitochondria as a target of environmental toxicants. Toxicol Sci (2013) 1.24
The maintenance of mitochondrial DNA integrity--critical analysis and update. Cold Spring Harb Perspect Biol (2013) 1.23
Impact of temozolomide on immune response during malignant glioma chemotherapy. Clin Dev Immunol (2012) 1.05
O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas. Cell Death Dis (2013) 0.98
XPC silencing in normal human keratinocytes triggers metabolic alterations that drive the formation of squamous cell carcinomas. J Clin Invest (2010) 0.92
TRAIL and paclitaxel synergize to kill U87 cells and U87-derived stem-like cells in vitro. Int J Mol Sci (2012) 0.91
Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells. Mol Cancer Ther (2008) 0.88
Mitochondrial DNA ligase is dispensable for the viability of cultured cells but essential for mtDNA maintenance. J Biol Chem (2013) 0.88
Requirement of the Saccharomyces cerevisiae APN1 gene for the repair of mitochondrial DNA alkylation damage. Environ Mol Mutagen (2009) 0.86
Temozolomide-mediated DNA methylation in human myeloid precursor cells: differential involvement of intrinsic and extrinsic apoptotic pathways. Clin Cancer Res (2013) 0.81
The L84F polymorphic variant of human O6-methylguanine-DNA methyltransferase alters stability in U87MG glioma cells but not temozolomide sensitivity. Neuro Oncol (2008) 0.78
NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells. Oncotarget (2016) 0.77
The approaches for manipulating mitochondrial proteome. Environ Mol Mutagen (2010) 0.76
Quantitative PCR analysis of diepoxybutane and epihalohydrin damage to nuclear versus mitochondrial DNA. Mutat Res (2009) 0.75
Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med (2010) 29.75
Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood (2004) 7.21
Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat Med (2009) 3.17
Precise segmental renal artery clamping under the guidance of dual-source computed tomography angiography during laparoscopic partial nephrectomy. Eur Urol (2012) 2.95
The intracellular localization of APE1/Ref-1: more than a passive phenomenon? Antioxid Redox Signal (2005) 2.75
Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice. Neuron (2010) 2.69
A complete sequence of the T. tengcongensis genome. Genome Res (2002) 2.60
The many functions of APE1/Ref-1: not only a DNA repair enzyme. Antioxid Redox Signal (2009) 2.43
Novel as1 and as2 defects in leaf adaxial-abaxial polarity reveal the requirement for ASYMMETRIC LEAVES1 and 2 and ERECTA functions in specifying leaf adaxial identity. Development (2003) 2.17
A "dock, lock, and latch" structural model for a staphylococcal adhesin binding to fibrinogen. Cell (2003) 2.06
Low-calcium serum-free defined medium selects for growth of normal prostatic epithelial stem cells. Cancer Res (2006) 2.02
Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability. Clin Cancer Res (2006) 2.02
The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target. Mol Aspects Med (2007) 2.01
Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition. Mol Cancer Ther (2004) 1.99
Safety and long-term efficacy of endovascular treatment of small posterior communicating artery aneurysms by coiling with or without stent: a single center retrospective study. Clin Neurol Neurosurg (2013) 1.97
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming. J Cell Biol (2009) 1.80
A 'Collagen Hug' model for Staphylococcus aureus CNA binding to collagen. EMBO J (2005) 1.78
Chronic tumor necrosis factor-alpha inhibition enhances NO modulation of vascular function in estrogen-deficient rats. Hypertension (2005) 1.75
Autophagy regulates phagocytosis by modulating the expression of scavenger receptors. Immunity (2013) 1.73
Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes. Nat Neurosci (2005) 1.73
Update on late relapse of germ cell tumor: a clinical and molecular analysis. J Clin Oncol (2003) 1.70
US-guided percutaneous microwave coagulation of small breast cancers: a clinical study. Radiology (2012) 1.66
The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress. DNA Repair (Amst) (2005) 1.64
A family of putative MSCRAMMs from Enterococcus faecalis. Microbiology (2004) 1.63
DNA repair in neurons: so if they don't divide what's to repair? Mutat Res (2006) 1.61
Manipulation of base excision repair to sensitize ovarian cancer cells to alkylating agent temozolomide. Clin Cancer Res (2007) 1.60
APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. Mol Cell Biol (2009) 1.58
Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1. Antioxid Redox Signal (2008) 1.58
Voice F0 responses to pitch-shifted voice feedback during English speech. J Acoust Soc Am (2007) 1.58
Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells. Hum Gene Ther (2003) 1.58
Tumor necrosis factor-alpha and vascular angiotensin II in estrogen-deficient rats. Hypertension (2006) 1.57
In vitro culturing and characteristics of transit amplifying epithelial cells from human prostate tissue. J Cell Biochem (2004) 1.57
A self-assembled DNA nanostructure-amplified quartz crystal microbalance with dissipation biosensing platform for nucleic acids. Chem Commun (Camb) (2012) 1.56
Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential. Proc Natl Acad Sci U S A (2011) 1.55
PTEN and p53 are required for hypoxia induced expression of maspin in glioblastoma cells. Cell Cycle (2009) 1.54
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. J Clin Invest (2009) 1.50
PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors. Blood (2004) 1.47
Selenomethionine regulation of p53 by a ref1-dependent redox mechanism. Proc Natl Acad Sci U S A (2002) 1.45
Cardiac effects of amiloride and of enalapril in the spontaneously hypertensive rat. J Hypertens (2003) 1.41
Decreased levels and function of circulating endothelial progenitor cells in unruptured intracranial saccular aneurysm patients. Neurol Sci (2013) 1.40
Identification and preliminary characterization of cell-wall-anchored proteins of Staphylococcus epidermidis. Microbiology (2005) 1.37
Stimulated innate resistance of lung epithelium protects mice broadly against bacteria and fungi. Am J Respir Cell Mol Biol (2009) 1.36
Endothelial cells in the early murine yolk sac give rise to CD41-expressing hematopoietic cells. Stem Cells Dev (2005) 1.35
Inducible innate resistance of lung epithelium to infection. Annu Rev Physiol (2010) 1.34
Conditional targeting of the DNA repair enzyme hOGG1 into mitochondria. J Biol Chem (2002) 1.34
Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP. Nucleic Acids Res (2005) 1.33
Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells. Mol Cancer Ther (2004) 1.33
Enhanced mtDNA repair capacity protects pulmonary artery endothelial cells from oxidant-mediated death. Am J Physiol Lung Cell Mol Physiol (2002) 1.32
Phenotypic correction of primary Fanconi anemia T cells with retroviral vectors as a diagnostic tool. Exp Hematol (2002) 1.31
Phase I safety, pharmacokinetic, and pharmacodynamic study of SAR245408 (XL147), an oral pan-class I PI3K inhibitor, in patients with advanced solid tumors. Clin Cancer Res (2013) 1.31
Redox regulation of DNA repair: implications for human health and cancer therapeutic development. Antioxid Redox Signal (2010) 1.31
Randomized trial of autologous cellular immunotherapy with sipuleucel-T in androgen-dependent prostate cancer. Clin Cancer Res (2011) 1.29
Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress. J Biol Chem (2012) 1.29
Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress. Glia (2003) 1.27
Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells. J Pharmacol Exp Ther (2010) 1.27
A streptococcal collagen-like protein interacts with the alpha2beta1 integrin and induces intracellular signaling. J Biol Chem (2005) 1.27
Assessment of prokaryotic collagen-like sequences derived from streptococcal Scl1 and Scl2 proteins as a source of recombinant GXY polymers. Appl Microbiol Biotechnol (2006) 1.26
Going ape as an approach to cancer therapeutics. Antioxid Redox Signal (2009) 1.25
Implications of apurinic/apyrimidinic endonuclease in reactive oxygen signaling response after cisplatin treatment of dorsal root ganglion neurons. Cancer Res (2008) 1.25
Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy. Cancers (Basel) (2011) 1.25
Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells. Proteomics (2009) 1.23
Role of notch-1 and E-cadherin in the differential response to calcium in culturing normal versus malignant prostate cells. Cancer Res (2005) 1.23
Angiotensin II-induced MMP-2 release from endothelial cells is mediated by TNF-alpha. Am J Physiol Cell Physiol (2003) 1.23
Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain. Blood (2006) 1.22
Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential. Cytometry A (2010) 1.22
Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone. Anticancer Res (2004) 1.22
Pretreatment of epithelial cells with rifaximin alters bacterial attachment and internalization profiles. Antimicrob Agents Chemother (2009) 1.20
Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth. DNA Repair (Amst) (2007) 1.18
Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing. Cancer Res (2003) 1.17
A novel binding site in collagen type III for integrins alpha1beta1 and alpha2beta1. J Biol Chem (2005) 1.15
Certification assays for HIV-1-based vectors: frequent passage of gag sequences without evidence of replication-competent viruses. Mol Ther (2003) 1.15
Implication of p53 in base excision DNA repair: in vivo evidence. Oncogene (2002) 1.14
Bacillus anthracis internalization by human fibroblasts and epithelial cells. Cell Microbiol (2007) 1.14
Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation. Exp Hematol (2008) 1.13
The Enterococcus faecalis MSCRAMM ACE binds its ligand by the Collagen Hug model. J Biol Chem (2007) 1.13
Damage-associated molecular patterns (DAMPs) in preterm labor with intact membranes and preterm PROM: a study of the alarmin HMGB1. J Matern Fetal Neonatal Med (2011) 1.13
Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice. Transplantation (2009) 1.12
Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment. Hum Gene Ther (2004) 1.12
UVB radiation-mediated inhibition of contact hypersensitivity reactions is dependent on the platelet-activating factor system. J Invest Dermatol (2008) 1.11
Interactions of apurinic/apyrimidinic endonuclease with a redox inhibitor: evidence for an alternate conformation of the enzyme. Biochemistry (2010) 1.10
Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells. Blood (2007) 1.10
Protein phosphatase PP4 is overexpressed in human breast and lung tumors. Cell Res (2008) 1.10
A signature of maternal anti-fetal rejection in spontaneous preterm birth: chronic chorioamnionitis, anti-human leukocyte antigen antibodies, and C4d. PLoS One (2011) 1.10
Prognostic role of Ape/Ref-1 subcellular expression in stage I-III breast carcinomas. Oncol Rep (2001) 1.08
Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population. Carcinogenesis (2013) 1.08
Potential dissemination of Bacillus anthracis utilizing human lung epithelial cells. Cell Microbiol (2007) 1.08
Interaction between Rice stripe virus disease-specific protein and host PsbP enhances virus symptoms. Mol Plant (2013) 1.07
Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions. DNA Repair (Amst) (2009) 1.07
Design and synthesis of novel quinone inhibitors targeted to the redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (Ape1/ref-1). J Med Chem (2010) 1.07
Enhancement of cisplatin [cis-diammine dichloroplatinum (II)] cytotoxicity by O6-benzylguanine involves endoplasmic reticulum stress. J Pharmacol Exp Ther (2008) 1.06
[Epidemiological survey of mental illnesses in the people aged 15 and older in Zhejiang Province, China]. Zhonghua Yu Fang Yi Xue Za Zhi (2005) 1.04
A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death. Proc Natl Acad Sci U S A (2009) 1.04
Downregulation of ABCG2 expression in glioblastoma cancer stem cells with miRNA-328 may decrease their chemoresistance. Med Sci Monit (2010) 1.02
Chemotherapeutic selectivity conferred by selenium: a role for p53-dependent DNA repair. Mol Cancer Ther (2007) 1.02
Decorin-binding sites in the adhesin DbpA from Borrelia burgdorferi: a synthetic peptide approach. J Biol Chem (2003) 1.02
A Dynamic Blood Information Management System Based on RFID. Conf Proc IEEE Eng Med Biol Soc (2005) 1.02
Age-associated impairment in vasorelaxation to fluid shear stress in the female vasculature is improved by TNF-alpha antagonism. Am J Physiol Heart Circ Physiol (2005) 1.01