James C Eisenach

Author PubWeight™ 123.37‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Animal models and the prediction of efficacy in clinical trials of analgesic drugs: a critical appraisal and call for uniform reporting standards. Pain 2008 3.08
2 Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics. Anesthesiology 2007 1.96
3 Individual differences in acute pain-induced endogenous analgesia predict time to resolution of postoperative pain in the rat. Anesthesiology 2015 1.52
4 Neostigmine decreases bupivacaine use by patient-controlled epidural analgesia during labor: a randomized controlled study. Anesth Analg 2009 1.50
5 Multifactorial preoperative predictors for postcesarean section pain and analgesic requirement. Anesthesiology 2006 1.50
6 Gabapentin acts within the locus coeruleus to alleviate neuropathic pain. Anesthesiology 2008 1.48
7 Data fabrication and article retraction: how not to get lost in the woods. Anesthesiology 2009 1.47
8 Effects of laparotomy on spontaneous exploratory activity and conditioned operant responding in the rat: a model for postoperative pain. Anesthesiology 2004 1.43
9 Peripheral nerve injury sensitizes the response to visceral distension but not its inhibition by the antidepressant milnacipran. Anesthesiology 2004 1.43
10 Intrathecal ketorolac does not improve acute or chronic pain after hip arthroplasty: a randomized controlled trial. J Anesth 2014 1.38
11 Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision. Anesthesiology 2007 1.30
12 Gabapentin activates spinal noradrenergic activity in rats and humans and reduces hypersensitivity after surgery. Anesthesiology 2007 1.27
13 Reversal of peripheral nerve injury-induced hypersensitivity in the postpartum period: role of spinal oxytocin. Anesthesiology 2013 1.27
14 Perineural clonidine reduces mechanical hypersensitivity and cytokine production in established nerve injury. Anesthesiology 2006 1.25
15 Intravenous remifentanil produces withdrawal hyperalgesia in volunteers with capsaicin-induced hyperalgesia. Anesth Analg 2003 1.24
16 Cyclooxygenase-1 in the spinal cord is altered after peripheral nerve injury. Anesthesiology 2003 1.23
17 Brain derived nerve growth factor induces spinal noradrenergic fiber sprouting and enhances clonidine analgesia following nerve injury in rats. Pain 2007 1.19
18 Pain intensity and duration can be enhanced by prior challenge: initial evidence suggestive of a role of microglial priming. J Pain 2010 1.19
19 Spinal glial activation contributes to postoperative mechanical hypersensitivity in the rat. J Pain 2006 1.18
20 Cyclooxygenase-1 in the spinal cord plays an important role in postoperative pain. Pain 2003 1.17
21 Morphological and pharmacological evidence for the role of peripheral prostaglandins in the pathogenesis of neuropathic pain. Eur J Neurosci 2002 1.16
22 Chronic constriction injury of sciatic nerve induces the up-regulation of descending inhibitory noradrenergic innervation to the lumbar dorsal horn of mice. Brain Res 2003 1.07
23 Alpha2-adrenoceptor stimulation transforms immune responses in neuritis and blocks neuritis-induced pain. J Neurosci 2005 1.06
24 Spinal alpha 2-adrenoceptor-mediated analgesia in neuropathic pain reflects brain-derived nerve growth factor and changes in spinal cholinergic neuronal function. Anesthesiology 2010 1.04
25 Medium and large injured dorsal root ganglion cells increase TRPV-1, accompanied by increased alpha2C-adrenoceptor co-expression and functional inhibition by clonidine. Pain 2005 1.03
26 Preoperative inhibition of cyclooxygenase-1 in the spinal cord reduces postoperative pain. Anesth Analg 2005 1.03
27 Role for both spinal cord COX-1 and COX-2 in maintenance of mechanical hypersensitivity following peripheral nerve injury. Brain Res 2002 1.01
28 Spinal nerve ligation increases alpha2-adrenergic receptor G-protein coupling in the spinal cord. Brain Res 2005 0.99
29 Age-dependent responses to thermal hyperalgesia and mechanical allodynia in a rat model of acute postoperative pain. Anesthesiology 2003 0.99
30 Age-dependent responses to nerve injury-induced mechanical allodynia. Anesthesiology 2006 0.98
31 Estrogen amplifies pain responses to uterine cervical distension in rats by altering transient receptor potential-1 function. Anesth Analg 2007 0.98
32 Abdominal surgery decreases food-reinforced operant responding in rats: relevance of incisional pain. Anesthesiology 2005 0.98
33 Riluzole and gabapentinoids activate glutamate transporters to facilitate glutamate-induced glutamate release from cultured astrocytes. Eur J Pharmacol 2011 0.96
34 Epidural neostigmine produces analgesia but also sedation in women after cesarean delivery. Anesthesiology 2004 0.96
35 Plasticity in action of intrathecal clonidine to mechanical but not thermal nociception after peripheral nerve injury. Anesthesiology 2003 0.95
36 Oral gabapentin activates spinal cholinergic circuits to reduce hypersensitivity after peripheral nerve injury and interacts synergistically with oral donepezil. Anesthesiology 2007 0.95
37 Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury. Neurosci Lett 2011 0.94
38 Intrathecal morphine and ketorolac analgesia after surgery: comparison of spontaneous and elicited responses in rats. Pain 2005 0.94
39 Intrathecal injection of cAMP response element binding protein (CREB) antisense oligonucleotide attenuates tactile allodynia caused by partial sciatic nerve ligation. Brain Res 2003 0.94
40 Preventing chronic pain after surgery: who, how, and when? Reg Anesth Pain Med 2006 0.93
41 Spinal noradrenergic activation mediates allodynia reduction from an allosteric adenosine modulator in a rat model of neuropathic pain. Pain 2002 0.93
42 Perineural alpha(2A)-adrenoceptor activation inhibits spinal cord neuroplasticity and tactile allodynia after nerve injury. Anesthesiology 2002 0.93
43 Depletion of endogenous noradrenaline does not prevent spinal cord plasticity following peripheral nerve injury. J Pain 2011 0.92
44 Clonidine reduces hypersensitivity and alters the balance of pro- and anti-inflammatory leukocytes after local injection at the site of inflammatory neuritis. Brain Behav Immun 2006 0.92
45 Effect of kappa opioid agonists on visceral nociception induced by uterine cervical distension in rats. Pain 2002 0.92
46 Allosteric adenosine receptor modulation reduces hypersensitivity following peripheral inflammation by a central mechanism. J Pharmacol Exp Ther 2003 0.92
47 Chronic estrogen sensitizes a subset of mechanosensitive afferents innervating the uterine cervix. J Neurophysiol 2005 0.92
48 Differing neurophysiologic mechanosensory input from glabrous and hairy skin in juvenile rats. J Neurophysiol 2010 0.91
49 alpha2-Adrenoceptor activation by clonidine enhances stimulation-evoked acetylcholine release from spinal cord tissue after nerve ligation in rats. Anesthesiology 2005 0.90
50 Knock down of the alpha 5 nicotinic acetylcholine receptor in spinal nerve-ligated rats alleviates mechanical allodynia. Pharmacol Biochem Behav 2004 0.90
51 Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat. Brain Res 2010 0.90
52 Clonidine maintains intrathecal self-administration in rats following spinal nerve ligation. Pain 2006 0.90
53 Predicting acute pain after cesarean delivery using three simple questions. Anesthesiology 2013 0.89
54 Safety in numbers: how do we study toxicity of spinal analgesics? Anesthesiology 2002 0.89
55 Intrathecal clonidine for postoperative analgesia in elderly patients: the influence of baricity on hemodynamic and analgesic effects. Anesth Analg 2004 0.89
56 Spinal cord dynorphin expression increases, but does not drive microglial prostaglandin production or mechanical hypersensitivity after incisional surgery in rats. Pain 2006 0.89
57 The effect of peripherally administered CDP-choline in an acute inflammatory pain model: the role of alpha7 nicotinic acetylcholine receptor. Anesth Analg 2009 0.89
58 Plasticity of spinal nicotinic acetylcholine receptors following spinal nerve ligation. Neurosci Res 2004 0.89
59 Immunocytochemical localization of the alpha3, alpha4, alpha5, alpha7, beta2, beta3 and beta4 nicotinic acetylcholine receptor subunits in the locus coeruleus of the rat. Brain Res 2003 0.88
60 Contribution of the chemokine (C-C motif) ligand 2 (CCL2) to mechanical hypersensitivity after surgical incision in rats. Anesthesiology 2010 0.88
61 Note of editorial concern. Anesthesiology 2011 0.87
62 Hyperexcitability of axotomized and neighboring unaxotomized sensory neurons is reduced days after perineural clonidine at the site of injury. J Neurophysiol 2005 0.87
63 Preoperative sciatic nerve block decreases mechanical allodynia more in young rats: is preemptive analgesia developmentally modulated? Anesth Analg 2004 0.87
64 Four PGE2 EP receptors are up-regulated in injured nerve following partial sciatic nerve ligation. Exp Neurol 2003 0.86
65 Intravenous butorphanol, meperidine, and their combination relieve pain and distress in women in labor. Anesthesiology 2005 0.86
66 Peripheral nerve injury alters the alpha2 adrenoceptor subtype activated by clonidine for analgesia. Anesthesiology 2002 0.86
67 Activation of glutamate transporters in the locus coeruleus paradoxically activates descending inhibition in rats. Brain Res 2010 0.85
68 Spinal noradrenaline transporter inhibition by reboxetine and Xen2174 reduces tactile hypersensitivity after surgery in rats. Pain 2005 0.85
69 Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors. J Neuroimmunol 2011 0.85
70 Epidural neostigmine: will it replace lipid soluble opioids for postoperative and labor analgesia? Anesth Analg 2009 0.85
71 Impaired Pain-evoked Analgesia after Nerve Injury in Rats Reflects Altered Glutamate Regulation in the Locus Coeruleus. Anesthesiology 2015 0.84
72 Peripheral block of the hyperpolarization-activated cation current (Ih) reduces mechanical allodynia in animal models of postoperative and neuropathic pain. Reg Anesth Pain Med 2005 0.84
73 Uterine cervical distension induces cFos expression in deep dorsal horn neurons of the rat spinal cord. Anesthesiology 2003 0.84
74 ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A- or alpha-2C-adrenergic receptors. J Pharmacol Exp Ther 2007 0.84
75 Gabapentin inhibits γ-amino butyric acid release in the locus coeruleus but not in the spinal dorsal horn after peripheral nerve injury in rats. Anesthesiology 2012 0.84
76 Electrical field stimulation to study inhibitory mechanisms in individual sensory neurons in culture. Anesthesiology 2004 0.84
77 Nicotinic acetylcholine receptor regulation of spinal norepinephrine release. Anesthesiology 2002 0.83
78 Pregnancy increases excitability of mechanosensitive afferents innervating the uterine cervix. Anesthesiology 2008 0.83
79 Intrathecal administration of a cylcooxygenase-1, but not a cyclooxygenase-2 inhibitor, reverses the effects of laparotomy on exploratory activity in rats. Anesth Analg 2006 0.83
80 Intrathecal lidocaine reverses tactile allodynia caused by nerve injuries and potentiates the antiallodynic effect of the COX inhibitor ketorolac. Anesthesiology 2003 0.83
81 Skin incision-induced receptive field responses of mechanosensitive peripheral neurons are developmentally regulated in the rat. J Neurophysiol 2012 0.83
82 Predictors of headache before, during, and after pregnancy: a cohort study. Headache 2012 0.83
83 A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury. J Pain 2011 0.82
84 Nociceptor-selective peripheral nerve block induces delayed mechanical hypersensitivity and neurotoxicity in rats. Anesthesiology 2014 0.82
85 Uterine cervical afferents in thoracolumbar dorsal root ganglia express transient receptor potential vanilloid type 1 channel and calcitonin gene-related peptide, but not P2X3 receptor and somatostatin. Anesthesiology 2006 0.82
86 Intrathecal morphine reduces allodynia after peripheral nerve injury in rats via activation of a spinal A1 adenosine receptor. Anesthesiology 2005 0.82
87 Did experimenter bias conceal the efficacy of spinal opioids in previous studies with the spinal nerve ligation model of neuropathic pain? Anesthesiology 2004 0.82
88 Developmental differences in spinal cyclooxygenase 1 expression after surgical incision. Anesthesiology 2006 0.82
89 Developmental differences in peripheral glabrous skin mechanosensory nerve receptive field and intracellular electrophysiologic properties: phenotypic characterization in infant and juvenile rats. Int J Dev Neurosci 2011 0.81
90 Repeated dosing with oral allosteric modulator of adenosine A1 receptor produces tolerance in rats with neuropathic pain. Anesthesiology 2004 0.81
91 Oral donepezil reduces hypersensitivity after nerve injury by a spinal muscarinic receptor mechanism. Anesthesiology 2007 0.81
92 Oxytocin inhibits the membrane depolarization-induced increase in intracellular calcium in capsaicin sensitive sensory neurons: a peripheral mechanism of analgesic action. Anesth Analg 2011 0.80
93 Spinal adrenergic and cholinergic receptor interactions activated by clonidine in postincisional pain. Anesthesiology 2003 0.80
94 Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations. Pain 2016 0.80
95 Neuronal nitric oxide synthase is upregulated in a subset of primary sensory afferents after nerve injury which are necessary for analgesia from alpha2-adrenoceptor stimulation. Brain Res 2006 0.80
96 Allosteric modulation of adenosine A1 receptor coupling to G-proteins in brain. J Neurochem 2005 0.80
97 Ondansetron reverses antihypersensitivity from clonidine in rats after peripheral nerve injury: role of γ-aminobutyric acid in α2-adrenoceptor and 5-HT3 serotonin receptor analgesia. Anesthesiology 2012 0.80
98 Electrophysiologic characteristics of large neurons in dorsal root ganglia during development and after hind paw incision in the rat. Anesthesiology 2008 0.80
99 Intrathecal clonidine reduces hypersensitivity after nerve injury by a mechanism involving spinal m4 muscarinic receptors. Anesth Analg 2003 0.80
100 Intrathecal adenosine following spinal nerve ligation in rat: short residence time in cerebrospinal fluid and no change in A(1) receptor binding. Anesthesiology 2002 0.80
101 Valproate prevents dysregulation of spinal glutamate and reduces the development of hypersensitivity in rats after peripheral nerve injury. J Pain 2013 0.80
102 Intrathecal clonidine and adenosine: effects on pain and sensory processing in patients with chronic regional pain syndrome. Pain 2015 0.79
103 Spinal adenosine receptor activation reduces hypersensitivity after surgery by a different mechanism than after nerve injury. Anesthesiology 2004 0.79
104 Preclinical toxicity screening of intrathecal oxytocin in rats and dogs. Anesthesiology 2014 0.79
105 A pain model after gynecologic surgery: the effect of intrathecal and systemic morphine. Anesth Analg 2006 0.79
106 Perineural clonidine reduces p38 mitogen-activated protein kinase activation in sensory neurons. Neuroreport 2006 0.79
107 Analgesia induced by perineural clonidine is enhanced in persistent neuritis. Neuroreport 2007 0.79
108 Effect of cyclooxygenase-1 inhibition in postoperative pain is developmentally regulated. Anesthesiology 2004 0.79
109 Spinal norepinephrine release from nitric oxide species is not increased following peripheral nerve injury in rats. Brain Res 2002 0.78
110 Intrathecal morphine reduces the visceromotor response to acute uterine cervical distension in an estrogen-independent manner. Anesthesiology 2003 0.78
111 Estrogen reduces efficacy of mu- but Not kappa-opioid agonist inhibition in response to uterine cervical distension. Anesthesiology 2002 0.78
112 Epidural ketamine in healthy children--what's the point? Anesth Analg 2003 0.78
113 Systemic, but not intrathecal ketorolac is antinociceptive to uterine cervical distension in rats. Pain 2003 0.78
114 Washington University and the why of anesthesiology. Anesthesiology 2011 0.78
115 Assessment of behavior during labor in rats and effect of intrathecal morphine. Anesthesiology 2008 0.78
116 Multiplicative interactions to enhance gabapentin to treat neuropathic pain. Eur J Pharmacol 2008 0.77
117 Adenosine reduces glutamate release in rat spinal synaptosomes. Anesthesiology 2005 0.77
118 Fishing for genes: practical ways to study genetic polymorphisms for pain. Anesthesiology 2004 0.77
119 Modeling individual recovery after peripheral nerve injury in rats and the effects of parturition. Anesthesiology 2014 0.77
120 Role of adenosine receptors in spinal G-protein activation after peripheral nerve injury. Anesthesiology 2002 0.77
121 Chronic activation of spinal adenosine A1 receptors results in hypersensitivity. Neuroreport 2006 0.77
122 Clonidine-induced neuronal activation in the spinal cord is altered after peripheral nerve injury. Anesthesiology 2003 0.77
123 Science marches forward: a new tool to study the progress of labor. Anesthesiology 2009 0.77
124 Intraspinal adenosine induces spinal cord norepinephrine release in spinal nerve-ligated rats but not in normal or sham controls. Anesthesiology 2003 0.77
125 Relief of hypersensitivity after nerve injury from systemic donepezil involves spinal cholinergic and γ-aminobutyric acid mechanisms. Anesthesiology 2013 0.76
126 Gabapentin loses efficacy over time after nerve injury in rats: role of glutamate transporter-1 in the locus coeruleus. Pain 2016 0.76
127 Wherefore Gabapentinoids?: Was There Rush Too Soon to Judgment? Anesthesiology 2016 0.75
128 Consent contraindicated? Science 2010 0.75
129 Pharmacology of opioid inhibition to noxious uterine cervical distension. Anesthesiology 2002 0.75
130 A Randomized Controlled Trial Comparing Two Multimodal Analgesic Techniques in Patients Predicted to Have Severe Pain After Cesarean Delivery. Anesth Analg 2016 0.75
131 Curiosity, discipline, and joy; and the greatest of these is joy. Anesthesiology 2009 0.75
132 Day-to-day experience in resolution of pain after surgery. Pain 2017 0.75
133 Case reports are leaving Anesthesiology, but not the specialty. Anesthesiology 2013 0.75
134 Assessment of Behavioral Disruption in Rats with Abdominal Inflammation Using Visual Cue Titration and the Five-choice Serial-reaction Time Task. Anesthesiology 2017 0.75
135 Anesthesiology and the press. Anesthesiology 2007 0.75
136 Intrathecal ketorolac enhances antinociception from clonidine. Anesth Analg 2003 0.75
137 Science and the mission of anesthesiology. Anesthesiology 2008 0.75
138 To our readers: an experiment in education. Anesthesiology 2010 0.75
139 Epidural Neostigmine versus Fentanyl to Decrease Bupivacaine Use in Patient-controlled Epidural Analgesia during Labor: A Randomized, Double-blind, Controlled Study. Anesthesiology 2017 0.75
140 Intrathecal ketorolac reverses hypersensitivity following acute fentanyl exposure. Anesthesiology 2002 0.75
141 Why is Karolinska on the cover of an American journal? Anesthesiology 2010 0.75
142 Finding and getting what you want when you want it just got easier at ANESTHESIOLOGY. Anesthesiology 2015 0.75
143 It's a bright and sunny day: Anesthesiology in 2011. Anesthesiology 2011 0.75
144 Anesthesiology and the Japanese Society of Anesthesiologists: the science is amazing. Anesthesiology 2010 0.75
145 The monoamine reuptake inhibitor milnacipran does not affect nociception to acute visceral distension in rats. Anesth Analg 2004 0.75
146 Blood pressure, but not cerebrospinal fluid fentanyl concentration, predicts duration of labor analgesia from spinal fentanyl. Anesthesiology 2010 0.75
147 Journal-related and other special activities at the 2008 American Society of Anesthesiologists Annual Meeting. Anesthesiology 2008 0.75
148 The antinociceptive effects of spinal cyclooxygenase inhibitors on uterine cervical distension. Brain Res 2004 0.75
149 To our authors. Anesthesiology 2009 0.75