Published in FEBS Lett on August 28, 2003
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TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice. J Mol Med (Berl) (2012) 1.52
Signaling components of redox active endosomes: the redoxosomes. Antioxid Redox Signal (2009) 1.50
Regulation of NADPH oxidase in vascular endothelium: the role of phospholipases, protein kinases, and cytoskeletal proteins. Antioxid Redox Signal (2009) 1.36
The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly. EMBO J (2004) 1.34
Critical role of lipid raft redox signaling platforms in endostatin-induced coronary endothelial dysfunction. Arterioscler Thromb Vasc Biol (2007) 1.29
Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease. Hum Mol Genet (2012) 1.25
Lipid rafts and caveolin-1 coordinate interleukin-1beta (IL-1beta)-dependent activation of NFkappaB by controlling endocytosis of Nox2 and IL-1beta receptor 1 from the plasma membrane. J Biol Chem (2009) 1.21
Priming of neutrophil oxidative burst in diabetes requires preassembly of the NADPH oxidase. J Leukoc Biol (2008) 1.19
Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways. Proc Natl Acad Sci U S A (2008) 1.13
The Leishmania donovani lipophosphoglycan excludes the vesicular proton-ATPase from phagosomes by impairing the recruitment of synaptotagmin V. PLoS Pathog (2009) 1.11
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Endothelium-neutrophil interactions in ANCA-associated diseases. J Am Soc Nephrol (2012) 1.02
Formation and function of ceramide-enriched membrane platforms with CD38 during M1-receptor stimulation in bovine coronary arterial myocytes. Am J Physiol Heart Circ Physiol (2008) 0.98
NADPH oxidase and lipid raft-associated redox signaling are required for PCB153-induced upregulation of cell adhesion molecules in human brain endothelial cells. Toxicol Appl Pharmacol (2009) 0.97
Lysosome fusion to the cell membrane is mediated by the dysferlin C2A domain in coronary arterial endothelial cells. J Cell Sci (2012) 0.95
Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts. Dev Neurosci (2009) 0.93
Polyunsaturated fatty acids modulate NOX 4 anion superoxide production in human fibroblasts. Biochem J (2007) 0.93
D1-like receptors regulate NADPH oxidase activity and subunit expression in lipid raft microdomains of renal proximal tubule cells. Hypertension (2009) 0.91
Leishmania promastigotes: building a safe niche within macrophages. Front Cell Infect Microbiol (2012) 0.90
Requirement of translocated lysosomal V1 H(+)-ATPase for activation of membrane acid sphingomyelinase and raft clustering in coronary endothelial cells. Mol Biol Cell (2012) 0.90
7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: roles of NADPH oxidase, mitochondria, and lipid rafts. Free Radic Biol Med (2006) 0.88
Recruitment of the cross-linked opsonic receptor CD32A (FcgammaRIIA) to high-density detergent-resistant membrane domains in human neutrophils. Biochem J (2004) 0.88
Fc gammaRIIIb triggers raft-dependent calcium influx in IgG-mediated responses in human neutrophils. J Biol Chem (2010) 0.87
Sulforaphane restores cellular glutathione levels and reduces chronic periodontitis neutrophil hyperactivity in vitro. PLoS One (2013) 0.86
New insights into the regulation of neutrophil NADPH oxidase activity in the phagosome: a focus on the role of lipid and Ca(2+) signaling. Antioxid Redox Signal (2012) 0.85
CIN85 modulates the down-regulation of Fc gammaRIIa expression and function by c-Cbl in a PKC-dependent manner in human neutrophils. J Biol Chem (2011) 0.84
SNARE-mediated rapid lysosome fusion in membrane raft clustering and dysfunction of bovine coronary arterial endothelium. Am J Physiol Heart Circ Physiol (2011) 0.81
The basic biology of redoxosomes in cytokine-mediated signal transduction and implications for disease-specific therapies. Biochemistry (2014) 0.81
MT6-MMP is present in lipid rafts and faces inward in living human PMNs but translocates to the cell surface during neutrophil apoptosis. Int Immunol (2010) 0.80
A nonpolar blueberry fraction blunts NADPH oxidase activation in neuronal cells exposed to tumor necrosis factor-α. Oxid Med Cell Longev (2012) 0.79
TSPO Finds NOX2 in Microglia for Redox Homeostasis. Trends Pharmacol Sci (2016) 0.78
Cholesterol: A modulator of the phagocyte NADPH oxidase activity - A cell-free study. Redox Biol (2014) 0.78
Docosahexaenoic acid and eicosapentaenoic acid antagonize the proinflammatory interactions of pneumolysin with human neutrophils. Infect Immun (2004) 0.77
NDS27 combines the effect of curcumin lysinate and hydroxypropyl-β-cyclodextrin to inhibit equine PKCδ and NADPH oxidase involved in the oxidative burst of neutrophils. FEBS Open Bio (2014) 0.75
Ca(2+)-regulated lysosome fusion mediates angiotensin II-induced lipid raft clustering in mesenteric endothelial cells. Hypertens Res (2016) 0.75
LysoPCs induce Hck- and PKCδ-mediated activation of PKCγ causing p47phox phosphorylation and membrane translocation in neutrophils. J Leukoc Biol (2016) 0.75
Killing activity of neutrophils is mediated through activation of proteases by K+ flux. Nature (2002) 7.53
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor. N Engl J Med (2009) 7.53
Defective acute inflammation in Crohn's disease: a clinical investigation. Lancet (2006) 5.83
Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. J Exp Med (2009) 3.58
The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems. Biochim Biophys Acta (2004) 2.39
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Res (2013) 1.92
Retracted The large-conductance Ca2+-activated K+ channel is essential for innate immunity. Nature (2004) 1.85
Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. Am J Gastroenterol (2009) 1.62
PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells. Am J Physiol Cell Physiol (2005) 1.56
The neutrophil respiratory burst and bacterial digestion in Crohn's disease. Dig Dis Sci (2010) 1.43
The immunopathogenesis of Crohn's disease: a three-stage model. Curr Opin Immunol (2009) 1.33
Phagocyte dysfunction and inflammatory bowel disease. Inflamm Bowel Dis (2008) 1.29
Ym1 is a neutrophil granule protein that crystallizes in p47phox-deficient mice. J Biol Chem (2001) 1.28
Reassessment of the microbicidal activity of reactive oxygen species and hypochlorous acid with reference to the phagocytic vacuole of the neutrophil granulocyte. J Med Microbiol (2003) 1.15
Catalase negative Staphylococcus aureus retain virulence in mouse model of chronic granulomatous disease. FEBS Lett (2002) 1.13
Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis. Am J Pathol (2007) 1.13
Crohn's disease: an immune deficiency state. Clin Rev Allergy Immunol (2010) 1.10
G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction. Glycobiology (2011) 1.08
UTP induces osteopontin expression through a coordinate action of NFkappaB, activator protein-1, and upstream stimulatory factor in arterial smooth muscle cells. J Biol Chem (2004) 1.00
Defective tumor necrosis factor release from Crohn's disease macrophages in response to Toll-like receptor activation: relationship to phenotype and genome-wide association susceptibility loci. Inflamm Bowel Dis (2012) 0.98
Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2-S100A10 protein interaction. J Med Chem (2011) 0.92
Impaired macrophage function following bacterial stimulation in chronic granulomatous disease. Immunology (2009) 0.91
PX domain takes shape. Curr Opin Hematol (2003) 0.91
Protein interactions between surface annexin A2 and S100A10 mediate adhesion of breast cancer cells to microvascular endothelial cells. FEBS Lett (2013) 0.90
Crohn's disease as an immunodeficiency. Expert Rev Clin Immunol (2010) 0.89
Phenotypic heterogeneity and evidence of a founder effect associated with G6PC3 mutations in patients with severe congenital neutropenia. Br J Haematol (2012) 0.89
Lipidomic profiling in Crohn's disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition. Int J Biochem Cell Biol (2012) 0.88
Granulocyte function in grancalcin-deficient mice. Mol Cell Biol (2003) 0.88
Subproteome analysis of the neutrophil cytoskeleton. Proteomics (2009) 0.87
Annexin A2 complexes with S100 proteins: structure, function and pharmacological manipulation. Br J Pharmacol (2014) 0.87
Diminished macrophage apoptosis and reactive oxygen species generation after phorbol ester stimulation in Crohn's disease. PLoS One (2009) 0.85
N-Formyl peptide receptor subtypes in human neutrophils activate L-plastin phosphorylation through different signal transduction intermediates. Biochem J (2004) 0.85
A Cy5-labeled S100A10 tracer used to identify inhibitors of the protein interaction with annexin A2. Assay Drug Dev Technol (2010) 0.84
Strategies to identify ion channel modulators: current and novel approaches to target neuropathic pain. Drug Discov Today (2004) 0.84
Disruption of macrophage pro-inflammatory cytokine release in Crohn's disease is associated with reduced optineurin expression in a subset of patients. Immunology (2015) 0.84
Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction. ChemMedChem (2012) 0.83
Delayed resolution of acute inflammation in ulcerative colitis is associated with elevated cytokine release downstream of TLR4. PLoS One (2010) 0.83
Involvement of protein kinase D in Fc gamma-receptor activation of the NADPH oxidase in neutrophils. Biochem J (2002) 0.82
CO binding and ligand discrimination in human myeloperoxidase. Biochemistry (2010) 0.80
Subcellular localisation of the p40phox component of NADPH oxidase involves direct interactions between the Phox homology domain and F-actin. Int J Biochem Cell Biol (2010) 0.80
Characterization of expression quantitative trait loci in the human colon. Inflamm Bowel Dis (2015) 0.78
The NADPH Oxidase and Microbial Killing by Neutrophils, With a Particular Emphasis on the Proposed Antimicrobial Role of Myeloperoxidase within the Phagocytic Vacuole. Microbiol Spectr (2016) 0.77
The role of grancalcin in adhesion of neutrophils. Cell Immunol (2006) 0.77
What is wrong with granulocytes in inflammatory bowel diseases? Dig Dis (2013) 0.77
Protein kinase C as an effector of lipid-derived second messengers. Methods Mol Biol (2009) 0.77
Mucosal transcriptomics implicates under expression of BRINP3 in the pathogenesis of ulcerative colitis. Inflamm Bowel Dis (2014) 0.77
A phagocyte dilemma... Nat Immunol (2011) 0.77
Shotgun cholanomics of ileal fluid. Biochimie (2012) 0.75