Published in J Biol Chem on May 06, 2005
Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab (2007) 5.04
GPIHBP1: an endothelial cell molecule important for the lipolytic processing of chylomicrons. Curr Opin Lipidol (2007) 2.01
The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons. J Biol Chem (2008) 1.91
Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment. J Clin Invest (2005) 1.37
Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families. J Biol Chem (2008) 1.26
Heparan sulfate 2-O-sulfotransferase is required for triglyceride-rich lipoprotein clearance. J Biol Chem (2009) 1.13
The metabolism of triglyceride-rich lipoproteins revisited: new players, new insight. Atherosclerosis (2009) 1.12
GPIHBP1, an endothelial cell transporter for lipoprotein lipase. J Lipid Res (2011) 1.08
Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells. Arterioscler Thromb Vasc Biol (2010) 1.08
Give me A5 for lipoprotein hydrolysis! J Clin Invest (2005) 1.07
The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries. Cell Metab (2014) 1.04
An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients. J Lipid Res (2008) 1.02
Effects of apoA-V on HDL and VLDL metabolism in APOC3 transgenic mice. J Lipid Res (2007) 0.98
APOA5 gene variation interacts with dietary fat intake to modulate obesity and circulating triglycerides in a Mediterranean population. J Nutr (2011) 0.96
Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans. J Clin Invest (2013) 0.95
The ins (cell) and outs (plasma) of apolipoprotein A-V. J Lipid Res (2008) 0.95
Apolipoprotein A-V associates with intrahepatic lipid droplets and influences triglyceride accumulation. Biochim Biophys Acta (2010) 0.93
Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1. Arterioscler Thromb Vasc Biol (2010) 0.93
Lipoprotein size and susceptibility to atherosclerosis--insights from genetically modified mouse models. Curr Drug Targets (2008) 0.92
Biogenesis of apolipoprotein A-V and its impact on VLDL triglyceride secretion. J Lipid Res (2010) 0.92
Apoprotein A-V: an important regulator of triglyceride metabolism. J Inherit Metab Dis (2008) 0.87
Apolipoprotein A-V dependent modulation of plasma triacylglycerol: a puzzlement. Biochim Biophys Acta (2011) 0.86
Influence of apolipoprotein A-V on the metabolic fate of triacylglycerol. Curr Opin Lipidol (2013) 0.84
Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels. J Lipid Res (2009) 0.83
The N-terminus of apolipoprotein A-V adopts a helix bundle molecular architecture. Biochemistry (2008) 0.83
Association of two common polymorphisms of apolipoprotein A5 gene with metabolic syndrome indicators in a North Iranian population, a cross-sectional study. J Diabetes Metab Disord (2014) 0.81
Apolipoprotein A-V gene therapy for disease prevention / treatment: a critical analysis. J Biomed Res (2015) 0.80
Effect of fenofibrate and atorvastatin on VLDL apoE metabolism in men with the metabolic syndrome. J Lipid Res (2012) 0.79
Apolipoprotein A-V N-terminal domain lipid interaction properties in vitro explain the hypertriglyceridemic phenotype associated with natural truncation mutants. J Biol Chem (2009) 0.79
Structural and functional analysis of APOA5 mutations identified in patients with severe hypertriglyceridemia. J Lipid Res (2013) 0.78
The carboxyl-terminal segment of apolipoprotein A-V undergoes a lipid-induced conformational change. Biochemistry (2010) 0.77
Aberrant hetero-disulfide bond formation by the hypertriglyceridemia-associated p.Gly185Cys APOA5 variant (rs2075291). Arterioscler Thromb Vasc Biol (2014) 0.77
ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency. J Lipid Res (2008) 0.76
Lipoprotein lipase activity and interactions studied in human plasma by isothermal titration calorimetry. J Lipid Res (2016) 0.75
Increased apolipoprotein A5 expression in human and rat non-alcoholic fatty livers. Pathology (2015) 0.75
Apolipoprotein C-II: New findings related to genetics, biochemistry, and role in triglyceride metabolism. Atherosclerosis (2017) 0.75
Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab (2007) 5.04
Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue. Proc Natl Acad Sci U S A (2006) 2.90
GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries. Cell Metab (2010) 2.75
The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons. J Biol Chem (2008) 1.91
Apolipoprotein A-I assumes a "looped belt" conformation on reconstituted high density lipoprotein. J Biol Chem (2006) 1.79
Apolipoprotein E: from lipid transport to neurobiology. Prog Lipid Res (2010) 1.63
The C-terminal domain of apolipoprotein A-I contains a lipid-sensitive conformational trigger. Nat Struct Biol (2003) 1.61
Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis. J Clin Invest (2013) 1.61
Curcumin nanodisk-induced apoptosis in mantle cell lymphoma. Leuk Lymphoma (2011) 1.54
Effects of acupuncture and exercise on insulin sensitivity, adipose tissue characteristics, and markers of coagulation and fibrinolysis in women with polycystic ovary syndrome: secondary analyses of a randomized controlled trial. Fertil Steril (2011) 1.52
Reconstituted high density lipoprotein enriched with the polyene antibiotic amphotericin B. J Lipid Res (2005) 1.52
Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution. Biochim Biophys Acta (2007) 1.39
The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction. J Clin Invest (2011) 1.36
Calcium triggers folding of lipoprotein lipase into active dimers. J Biol Chem (2005) 1.32
Local suppression of T cell responses by arginase-induced L-arginine depletion in nonhealing leishmaniasis. PLoS Negl Trop Dis (2009) 1.29
Structure and interfacial properties of human apolipoprotein A-V. J Biol Chem (2003) 1.27
Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family. Biochemistry (2007) 1.26
Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families. J Biol Chem (2008) 1.26
Structural basis for the conformational adaptability of apolipophorin III, a helix-bundle exchangeable apolipoprotein. Proc Natl Acad Sci U S A (2002) 1.25
Apolipoprotein CIII promotes Ca2+-dependent beta cell death in type 1 diabetes. Proc Natl Acad Sci U S A (2004) 1.23
All-trans-retinoic acid nanodisks. Int J Pharm (2007) 1.23
Structure-function studies of human apolipoprotein A-V: a regulator of plasma lipid homeostasis. Biochemistry (2003) 1.22
Transthyretin constitutes a functional component in pancreatic beta-cell stimulus-secretion coupling. Proc Natl Acad Sci U S A (2005) 1.22
Helix orientation of the functional domains in apolipoprotein e in discoidal high density lipoprotein particles. J Biol Chem (2004) 1.22
Apolipophorin III: role model apolipoprotein. Insect Biochem Mol Biol (2006) 1.21
Adipose tissue has aberrant morphology and function in PCOS: enlarged adipocytes and low serum adiponectin, but not circulating sex steroids, are strongly associated with insulin resistance. J Clin Endocrinol Metab (2010) 1.21
Structure and dynamics of human apolipoprotein CIII. J Biol Chem (2008) 1.18
Characterization of apolipoprotein A-V structure and mode of plasma triacylglycerol regulation. Curr Opin Lipidol (2007) 1.15
Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport. Am J Physiol Endocrinol Metab (2011) 1.14
Nanodisk-associated amphotericin B clears Leishmania major cutaneous infection in susceptible BALB/c mice. Antimicrob Agents Chemother (2006) 1.14
Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea. Eur Heart J (2011) 1.14
Apolipoproteins C-I and C-III inhibit lipoprotein lipase activity by displacement of the enzyme from lipid droplets. J Biol Chem (2013) 1.14
Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase. J Lipid Res (2008) 1.12
Curcumin nanodisks: formulation and characterization. Nanomedicine (2010) 1.12
Retention of low-density lipoprotein in atherosclerotic lesions of the mouse: evidence for a role of lipoprotein lipase. Circ Res (2007) 1.11
A two-step binding model of PCSK9 interaction with the low density lipoprotein receptor. J Biol Chem (2010) 1.10
The distribution of lipoprotein lipase in rat adipose tissue. Changes with nutritional state engage the extracellular enzyme. J Biol Chem (2003) 1.09
Effects of heparin on the uptake of lipoprotein lipase in rat liver. BMC Physiol (2004) 1.09
Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4. Am J Respir Crit Care Med (2013) 1.09
Apolipoprotein A-V association with intracellular lipid droplets. J Lipid Res (2007) 1.09
Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells. Arterioscler Thromb Vasc Biol (2010) 1.08
Apolipoprotein A-V; a potent triglyceride reducer. Atherosclerosis (2011) 1.08
Combined N- and C-terminal truncation of human apolipoprotein A-I yields a folded, functional central domain. Biochemistry (2005) 1.08
Molecular studies of pH-dependent ligand interactions with the low-density lipoprotein receptor. Biochemistry (2008) 1.07
Effect of apolipoprotein A-V on plasma triglyceride, lipoprotein size, and composition in genetically engineered mice. J Lipid Res (2007) 1.05
pH6 antigen of Yersinia pestis interacts with plasma lipoproteins and cell membranes. J Lipid Res (2002) 1.05
Rapid subunit exchange in dimeric lipoprotein lipase and properties of the inactive monomer. J Biol Chem (2004) 1.04
All trans retinoic acid nanodisks enhance retinoic acid receptor mediated apoptosis and cell cycle arrest in mantle cell lymphoma. Br J Haematol (2010) 1.04
Calreticulin promotes folding/dimerization of human lipoprotein lipase expressed in insect cells (sf21). J Biol Chem (2003) 1.03
Intracellular lipid droplet targeting by apolipoprotein A-V requires the carboxyl-terminal segment. J Lipid Res (2008) 0.97
11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues. Am J Physiol Endocrinol Metab (2007) 0.97
Postprandial regulation of blood lipids and adipose tissue lipoprotein lipase in type 2 diabetes patients and healthy control subjects. Atherosclerosis (2003) 0.96
Lipid-induced extension of apolipoprotein E helix 4 correlates with low density lipoprotein receptor binding ability. J Biol Chem (2006) 0.95
TREM2 regulates microglial cell activation in response to demyelination in vivo. Acta Neuropathol (2015) 0.95
Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men. Atherosclerosis (2003) 0.95
The ins (cell) and outs (plasma) of apolipoprotein A-V. J Lipid Res (2008) 0.95
The C terminus of apolipoprotein A-V modulates lipid-binding activity. J Biol Chem (2007) 0.94
Tissue-specific postprandial clearance is the major determinant of PPARgamma-induced triglyceride lowering in the rat. Am J Physiol Regul Integr Comp Physiol (2008) 0.94
Structure-guided protein engineering modulates helix bundle exchangeable apolipoprotein properties. J Biol Chem (2003) 0.94
Amphotericin B induces interdigitation of apolipoprotein stabilized nanodisk bilayers. Biochim Biophys Acta (2007) 0.94
Targeting nanodisks via a single chain variable antibody--apolipoprotein chimera. Biochem Biophys Res Commun (2008) 0.93
Apolipoprotein A-V associates with intrahepatic lipid droplets and influences triglyceride accumulation. Biochim Biophys Acta (2010) 0.93
Nanodisks derived from amphotericin B lipid complex. J Pharm Sci (2008) 0.93
Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1. Arterioscler Thromb Vasc Biol (2010) 0.93
Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue. BMC Physiol (2012) 0.93
Nutritional regulation of lipoprotein lipase in mice. Int J Biochem Cell Biol (2004) 0.92
Lipoprotein lipase is differentially expressed in prognostic subsets of chronic lymphocytic leukemia but displays invariably low catalytical activity. Leuk Res (2009) 0.92
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking. J Cell Sci (2011) 0.92
A single bolus of a low molecular weight heparin to patients on haemodialysis depletes lipoprotein lipase stores and retards triglyceride clearing. Nephrol Dial Transplant (2005) 0.92
Characterization of low density lipoprotein receptor ligand interactions by fluorescence resonance energy transfer. J Lipid Res (2006) 0.91
Triacylglycerol-rich lipoproteins protect lipoprotein lipase from inactivation by ANGPTL3 and ANGPTL4. Biochim Biophys Acta (2012) 0.91
Lipoprotein lipase in the kidney: activity varies widely among animal species. Am J Physiol Renal Physiol (2004) 0.91
Lipid binding ability of human apolipoprotein E N-terminal domain isoforms: correlation with protein stability? Biophys Chem (2003) 0.91
Endothelial and lipoprotein lipases in human and mouse placenta. J Lipid Res (2005) 0.90
Impact of apolipoprotein E on Alzheimer's disease. Curr Alzheimer Res (2013) 0.90
Differential lipid binding of truncation mutants of Galleria mellonella apolipophorin III. Biochemistry (2002) 0.90
Lowering apolipoprotein CIII delays onset of type 1 diabetes. Proc Natl Acad Sci U S A (2011) 0.90
Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester. J Clin Endocrinol Metab (2013) 0.89
Apolipoprotein E isoform-specific binding to the low-density lipoprotein receptor. Anal Biochem (2007) 0.89
Lipid-triggered conformational switch of apolipophorin III helix bundle to an extended helix organization. J Mol Biol (2002) 0.89
Functional analyses of human apolipoprotein CII by site-directed mutagenesis: identification of residues important for activation of lipoprotein lipase. J Biol Chem (2001) 0.89
Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise. Proc Natl Acad Sci U S A (2014) 0.88
Apolipophorin III: a lipid-triggered molecular switch. Insect Biochem Mol Biol (2003) 0.88
Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4 are formed. Biochem Biophys Res Commun (2012) 0.87
Spectroscopic studies of amphotericin B solubilized in nanoscale bilayer membranes. Biochim Biophys Acta (2006) 0.86
Anionic phospholipids inhibit apolipoprotein E--low-density lipoprotein receptor interactions. Biochem Biophys Res Commun (2007) 0.86
Apolipoprotein A-V dependent modulation of plasma triacylglycerol: a puzzlement. Biochim Biophys Acta (2011) 0.86
A transcription-dependent mechanism, akin to that in adipose tissue, modulates lipoprotein lipase activity in rat heart. Am J Physiol Endocrinol Metab (2007) 0.86