Published in Biochemistry on February 28, 2007
The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons. J Biol Chem (2008) 1.91
Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families. J Biol Chem (2008) 1.26
APOA5 gene variation interacts with dietary fat intake to modulate obesity and circulating triglycerides in a Mediterranean population. J Nutr (2011) 0.96
The ins (cell) and outs (plasma) of apolipoprotein A-V. J Lipid Res (2008) 0.95
Atorvastatin and fenofibrate increase apolipoprotein AV and decrease triglycerides by up-regulating peroxisome proliferator-activated receptor-alpha. Br J Pharmacol (2009) 0.94
Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1. Arterioscler Thromb Vasc Biol (2010) 0.93
Apolipoprotein A-V associates with intrahepatic lipid droplets and influences triglyceride accumulation. Biochim Biophys Acta (2010) 0.93
Biogenesis of apolipoprotein A-V and its impact on VLDL triglyceride secretion. J Lipid Res (2010) 0.92
The paradox of ApoA5 modulation of triglycerides: evidence from clinical and basic research. Clin Biochem (2012) 0.91
Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1. J Biol Chem (2012) 0.90
Apoprotein A-V: an important regulator of triglyceride metabolism. J Inherit Metab Dis (2008) 0.87
Apolipoprotein A-V dependent modulation of plasma triacylglycerol: a puzzlement. Biochim Biophys Acta (2011) 0.86
Determinants of plasma apolipoprotein A-V and APOA5 gene transcripts in humans. J Intern Med (2008) 0.85
Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels. J Lipid Res (2009) 0.83
The N-terminus of apolipoprotein A-V adopts a helix bundle molecular architecture. Biochemistry (2008) 0.83
Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice. PLoS One (2012) 0.81
Apolipoprotein A-V gene therapy for disease prevention / treatment: a critical analysis. J Biomed Res (2015) 0.80
SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity. J Clin Invest (2016) 0.79
Apolipoprotein A-V N-terminal domain lipid interaction properties in vitro explain the hypertriglyceridemic phenotype associated with natural truncation mutants. J Biol Chem (2009) 0.79
Structural and functional analysis of APOA5 mutations identified in patients with severe hypertriglyceridemia. J Lipid Res (2013) 0.78
Apolipoprotein A-V deficiency enhances chylomicron production in lymph fistula mice. Am J Physiol Gastrointest Liver Physiol (2015) 0.77
The carboxyl-terminal segment of apolipoprotein A-V undergoes a lipid-induced conformational change. Biochemistry (2010) 0.77
Sorting receptor SORLA: cellular mechanisms and implications for disease. Cell Mol Life Sci (2016) 0.75
Association of APOA5 Gene Promoter Region -1131T>C Polymorphism (rs662799) to Plasma Triglyceride Level in Patients with Type 2 Diabetic Nephropathy. J Clin Diagn Res (2016) 0.75
Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity. J Biol Chem (2016) 0.75
Increased apolipoprotein A5 expression in human and rat non-alcoholic fatty livers. Pathology (2015) 0.75
Xuezhikang contributes to greater triglyceride reduction than simvastatin in hypertriglyceridemia rats by up-regulating apolipoprotein A5 via the PPARα signaling pathway. PLoS One (2017) 0.75
Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab (2007) 5.04
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein. Proc Natl Acad Sci U S A (2005) 4.34
Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue. Proc Natl Acad Sci U S A (2006) 2.90
GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries. Cell Metab (2010) 2.75
The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons. J Biol Chem (2008) 1.91
Apolipoprotein A-I assumes a "looped belt" conformation on reconstituted high density lipoprotein. J Biol Chem (2006) 1.79
Apolipoprotein E: from lipid transport to neurobiology. Prog Lipid Res (2010) 1.63
The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis. Nat Med (2010) 1.63
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11. Biochemistry (2006) 1.63
The C-terminal domain of apolipoprotein A-I contains a lipid-sensitive conformational trigger. Nat Struct Biol (2003) 1.61
Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis. J Clin Invest (2013) 1.61
Apolipoprotein A-V-heparin interactions: implications for plasma lipoprotein metabolism. J Biol Chem (2005) 1.55
Curcumin nanodisk-induced apoptosis in mantle cell lymphoma. Leuk Lymphoma (2011) 1.54
Reconstituted high density lipoprotein enriched with the polyene antibiotic amphotericin B. J Lipid Res (2005) 1.52
Effects of acupuncture and exercise on insulin sensitivity, adipose tissue characteristics, and markers of coagulation and fibrinolysis in women with polycystic ovary syndrome: secondary analyses of a randomized controlled trial. Fertil Steril (2011) 1.52
The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding. FEBS Lett (2002) 1.48
Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution. Biochim Biophys Acta (2007) 1.39
The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction. J Clin Invest (2011) 1.36
Calcium triggers folding of lipoprotein lipase into active dimers. J Biol Chem (2005) 1.32
Local suppression of T cell responses by arginase-induced L-arginine depletion in nonhealing leishmaniasis. PLoS Negl Trop Dis (2009) 1.29
Structure and interfacial properties of human apolipoprotein A-V. J Biol Chem (2003) 1.27
Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families. J Biol Chem (2008) 1.26
Structural basis for the conformational adaptability of apolipophorin III, a helix-bundle exchangeable apolipoprotein. Proc Natl Acad Sci U S A (2002) 1.25
Apolipoprotein CIII promotes Ca2+-dependent beta cell death in type 1 diabetes. Proc Natl Acad Sci U S A (2004) 1.23
All-trans-retinoic acid nanodisks. Int J Pharm (2007) 1.23
Structure-function studies of human apolipoprotein A-V: a regulator of plasma lipid homeostasis. Biochemistry (2003) 1.22
Transthyretin constitutes a functional component in pancreatic beta-cell stimulus-secretion coupling. Proc Natl Acad Sci U S A (2005) 1.22
Helix orientation of the functional domains in apolipoprotein e in discoidal high density lipoprotein particles. J Biol Chem (2004) 1.22
Apolipophorin III: role model apolipoprotein. Insect Biochem Mol Biol (2006) 1.21
Adipose tissue has aberrant morphology and function in PCOS: enlarged adipocytes and low serum adiponectin, but not circulating sex steroids, are strongly associated with insulin resistance. J Clin Endocrinol Metab (2010) 1.21
Structure and dynamics of human apolipoprotein CIII. J Biol Chem (2008) 1.18
Characterization of apolipoprotein A-V structure and mode of plasma triacylglycerol regulation. Curr Opin Lipidol (2007) 1.15
Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport. Am J Physiol Endocrinol Metab (2011) 1.14
Nanodisk-associated amphotericin B clears Leishmania major cutaneous infection in susceptible BALB/c mice. Antimicrob Agents Chemother (2006) 1.14
Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea. Eur Heart J (2011) 1.14
Apolipoproteins C-I and C-III inhibit lipoprotein lipase activity by displacement of the enzyme from lipid droplets. J Biol Chem (2013) 1.14
Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members. Biochem J (2006) 1.13
Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase. J Lipid Res (2008) 1.12
Curcumin nanodisks: formulation and characterization. Nanomedicine (2010) 1.12
Retention of low-density lipoprotein in atherosclerotic lesions of the mouse: evidence for a role of lipoprotein lipase. Circ Res (2007) 1.11
A two-step binding model of PCSK9 interaction with the low density lipoprotein receptor. J Biol Chem (2010) 1.10
The distribution of lipoprotein lipase in rat adipose tissue. Changes with nutritional state engage the extracellular enzyme. J Biol Chem (2003) 1.09
Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4. Am J Respir Crit Care Med (2013) 1.09
Effects of heparin on the uptake of lipoprotein lipase in rat liver. BMC Physiol (2004) 1.09
Apolipoprotein A-V association with intracellular lipid droplets. J Lipid Res (2007) 1.09
Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells. Arterioscler Thromb Vasc Biol (2010) 1.08
Apolipoprotein A-V; a potent triglyceride reducer. Atherosclerosis (2011) 1.08
Combined N- and C-terminal truncation of human apolipoprotein A-I yields a folded, functional central domain. Biochemistry (2005) 1.08
Molecular studies of pH-dependent ligand interactions with the low-density lipoprotein receptor. Biochemistry (2008) 1.07
Functional organization of the sortilin Vps10p domain. J Biol Chem (2004) 1.05
pH6 antigen of Yersinia pestis interacts with plasma lipoproteins and cell membranes. J Lipid Res (2002) 1.05
Effect of apolipoprotein A-V on plasma triglyceride, lipoprotein size, and composition in genetically engineered mice. J Lipid Res (2007) 1.05
Rapid subunit exchange in dimeric lipoprotein lipase and properties of the inactive monomer. J Biol Chem (2004) 1.04
All trans retinoic acid nanodisks enhance retinoic acid receptor mediated apoptosis and cell cycle arrest in mantle cell lymphoma. Br J Haematol (2010) 1.04
Calreticulin promotes folding/dimerization of human lipoprotein lipase expressed in insect cells (sf21). J Biol Chem (2003) 1.03
Different motifs regulate trafficking of SorCS1 isoforms. Traffic (2008) 0.98
Intracellular lipid droplet targeting by apolipoprotein A-V requires the carboxyl-terminal segment. J Lipid Res (2008) 0.97
11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues. Am J Physiol Endocrinol Metab (2007) 0.97
Postprandial regulation of blood lipids and adipose tissue lipoprotein lipase in type 2 diabetes patients and healthy control subjects. Atherosclerosis (2003) 0.96
Lipid-induced extension of apolipoprotein E helix 4 correlates with low density lipoprotein receptor binding ability. J Biol Chem (2006) 0.95
TREM2 regulates microglial cell activation in response to demyelination in vivo. Acta Neuropathol (2015) 0.95
Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men. Atherosclerosis (2003) 0.95
The ins (cell) and outs (plasma) of apolipoprotein A-V. J Lipid Res (2008) 0.95
The C terminus of apolipoprotein A-V modulates lipid-binding activity. J Biol Chem (2007) 0.94
Tissue-specific postprandial clearance is the major determinant of PPARgamma-induced triglyceride lowering in the rat. Am J Physiol Regul Integr Comp Physiol (2008) 0.94
Structure-guided protein engineering modulates helix bundle exchangeable apolipoprotein properties. J Biol Chem (2003) 0.94
Amphotericin B induces interdigitation of apolipoprotein stabilized nanodisk bilayers. Biochim Biophys Acta (2007) 0.94
Targeting nanodisks via a single chain variable antibody--apolipoprotein chimera. Biochem Biophys Res Commun (2008) 0.93
Apolipoprotein A-V associates with intrahepatic lipid droplets and influences triglyceride accumulation. Biochim Biophys Acta (2010) 0.93
Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1. Arterioscler Thromb Vasc Biol (2010) 0.93
Nanodisks derived from amphotericin B lipid complex. J Pharm Sci (2008) 0.93
Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue. BMC Physiol (2012) 0.93
Nutritional regulation of lipoprotein lipase in mice. Int J Biochem Cell Biol (2004) 0.92
Lipoprotein lipase is differentially expressed in prognostic subsets of chronic lymphocytic leukemia but displays invariably low catalytical activity. Leuk Res (2009) 0.92
A single bolus of a low molecular weight heparin to patients on haemodialysis depletes lipoprotein lipase stores and retards triglyceride clearing. Nephrol Dial Transplant (2005) 0.92
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking. J Cell Sci (2011) 0.92
Triacylglycerol-rich lipoproteins protect lipoprotein lipase from inactivation by ANGPTL3 and ANGPTL4. Biochim Biophys Acta (2012) 0.91
Characterization of low density lipoprotein receptor ligand interactions by fluorescence resonance energy transfer. J Lipid Res (2006) 0.91
Lipoprotein lipase in the kidney: activity varies widely among animal species. Am J Physiol Renal Physiol (2004) 0.91
Lipid binding ability of human apolipoprotein E N-terminal domain isoforms: correlation with protein stability? Biophys Chem (2003) 0.91
Endothelial and lipoprotein lipases in human and mouse placenta. J Lipid Res (2005) 0.90
Impact of apolipoprotein E on Alzheimer's disease. Curr Alzheimer Res (2013) 0.90
Differential lipid binding of truncation mutants of Galleria mellonella apolipophorin III. Biochemistry (2002) 0.90
Lowering apolipoprotein CIII delays onset of type 1 diabetes. Proc Natl Acad Sci U S A (2011) 0.90
Functional analyses of human apolipoprotein CII by site-directed mutagenesis: identification of residues important for activation of lipoprotein lipase. J Biol Chem (2001) 0.89