Published in Circulation on February 11, 2003
Adipokines in inflammation and metabolic disease. Nat Rev Immunol (2011) 8.92
Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat Med (2005) 6.04
Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study. Eur Heart J (2009) 3.54
Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease. Cardiovasc Diabetol (2006) 3.31
Mesenteric fat as a source of C reactive protein and as a target for bacterial translocation in Crohn's disease. Gut (2011) 2.87
Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. J Biol Chem (2009) 2.69
Adiponectin as an anti-inflammatory factor. Clin Chim Acta (2007) 2.56
Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies. J Clin Invest (2007) 2.37
Adiponectin decreases C-reactive protein synthesis and secretion from endothelial cells: evidence for an adipose tissue-vascular loop. Arterioscler Thromb Vasc Biol (2008) 2.29
Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysis. Fertil Steril (2010) 2.25
Resistin, adiponectin, and risk of heart failure the Framingham offspring study. J Am Coll Cardiol (2008) 2.18
Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease. Gut (2005) 2.03
Adiponectin actions in the cardiovascular system. Cardiovasc Res (2006) 1.92
Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training. CMAJ (2005) 1.90
Inflammation, a link between obesity and cardiovascular disease. Mediators Inflamm (2010) 1.80
Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality. Am J Physiol Endocrinol Metab (2008) 1.79
Association of visceral fat accumulation and adiponectin levels with colorectal neoplasia. Dig Dis Sci (2008) 1.76
C-reactive protein as a predictor of disease in smokers and former smokers: a review. Int J Clin Pract (2009) 1.66
Joint association of glycemic load and alcohol intake with type 2 diabetes incidence in women. Am J Clin Nutr (2011) 1.63
Adiponectin protects against the development of systolic dysfunction following myocardial infarction. J Mol Cell Cardiol (2007) 1.55
Emerging markers of atherosclerosis before and after bariatric surgery. Obes Surg (2015) 1.55
Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Int J Med Sci (2006) 1.52
Adipocytokines in obesity and metabolic disease. J Endocrinol (2014) 1.49
The evolving role of C-reactive protein in atherothrombosis. Clin Chem (2008) 1.48
Circulating adiponectin concentrations in patients with congestive heart failure. Heart (2006) 1.47
Human C-reactive protein and the metabolic syndrome. Curr Opin Lipidol (2009) 1.40
Mesenteric fat in Crohn's disease: a pathogenetic hallmark or an innocent bystander? Gut (2006) 1.34
Adipokines: a link between obesity and cardiovascular disease. J Cardiol (2013) 1.29
Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients. Atherosclerosis (2008) 1.28
Adipose tissue dysfunction in nascent metabolic syndrome. J Obes (2013) 1.26
Adipocytokines and liver disease. J Gastroenterol (2008) 1.25
Adipose tissue dysregulation in patients with metabolic syndrome. J Clin Endocrinol Metab (2011) 1.25
Clinical review: adiponectin biology and its role in inflammation and critical illness. Crit Care (2011) 1.19
Pathophysiological significance of adiponectin. Med Mol Morphol (2007) 1.18
The peroxisome proliferator-activated receptor gamma agonist rosiglitazone ameliorates murine lupus by induction of adiponectin. J Immunol (2009) 1.17
Changes in serum adiponectin concentrations in critical illness: a preliminary investigation. Crit Care (2009) 1.16
Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation. J Immunol (2011) 1.16
Obesity and inflammation: epidemiology, risk factors, and markers of inflammation. Int J Endocrinol (2013) 1.12
Aberrant activation profile of cytokines and mitogen-activated protein kinases in type 2 diabetic patients with nephropathy. Clin Exp Immunol (2007) 1.12
Mechanisms of chronic state of inflammation as mediators that link obese adipose tissue and metabolic syndrome. Mediators Inflamm (2013) 1.11
CRP and adiponectin and its oligomers in the metabolic syndrome: evaluation of new laboratory-based biomarkers. Am J Clin Pathol (2008) 1.10
Role of adiponectin in metabolic and cardiovascular disease. J Exerc Rehabil (2014) 1.07
Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice. Genetics (2006) 1.07
CRP and the risk of atherosclerotic events. Semin Immunopathol (2009) 1.06
Lifestyle intervention and/or statins for the reduction of C-reactive protein in type 2 diabetes: from the look AHEAD study. Obesity (Silver Spring) (2013) 1.04
The long-term impact of intrauterine growth restriction in a diverse U.S. cohort of children: the EPOCH study. Obesity (Silver Spring) (2013) 1.02
Adiponectin in cardiovascular inflammation and obesity. Int J Inflam (2011) 1.01
Prospective randomized study for optimal insulin therapy in type 2 diabetic patients with secondary failure. Cardiovasc Diabetol (2008) 1.00
Obesity and dementia: adipokines interact with the brain. Eur Neuropsychopharmacol (2014) 1.00
The usefulness of circulating adipokine levels for the assessment of obesity-related health problems. Int J Med Sci (2008) 0.99
Inflammation in Polycystic Ovary Syndrome: underpinning of insulin resistance and ovarian dysfunction. Steroids (2011) 0.97
Adiponectin, resistin and IL-6 plasma levels in subjects with diabetic foot and possible correlations with clinical variables and cardiovascular co-morbidity. Cardiovasc Diabetol (2010) 0.97
Association of adiponectin levels and insulin demand in critically ill patients. Diabetes Metab Syndr Obes (2011) 0.95
Adiponectin action: a combination of endocrine and autocrine/paracrine effects. Front Endocrinol (Lausanne) (2011) 0.95
Abdominal obesity exhibits distinct effect on inflammatory and anti-inflammatory proteins in apparently healthy Japanese men. Cardiovasc Diabetol (2007) 0.94
Plasma resistin, adiponectin, and risk of incident atrial fibrillation: the Framingham Offspring Study. Am Heart J (2011) 0.94
Obese reproductive-age women exhibit a proatherogenic inflammatory response during hyperglycemia. Obesity (Silver Spring) (2007) 0.93
Metabolic factors, adipose tissue, and plasminogen activator inhibitor-1 levels in type 2 diabetes: findings from the look AHEAD study. Arterioscler Thromb Vasc Biol (2011) 0.93
High-sensitivity C-reactive protein to detect metabolic syndrome in a centrally obese population: a cross-sectional analysis. Cardiovasc Diabetol (2012) 0.92
Tumoral CRP expression in thoracic esophageal squamous cell cancers is associated with poor outcomes. Surg Today (2012) 0.92
Plasma adiponectin concentrations in non-pregnant, normal and overweight pregnant women. J Perinat Med (2007) 0.92
Hypoadiponectinemia in obese subjects with type II diabetes: A close association with central obesity indices. J Res Med Sci (2011) 0.92
Obesity, inflammation, and lung injury (OILI): the good. Mediators Inflamm (2014) 0.91
Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease. Circ Res (2016) 0.91
Resistin: a hormone which induces insulin resistance is increased in normal pregnancy. J Perinat Med (2007) 0.90
Resistin-induced stromal cell-derived factor-1 expression through Toll-like receptor 4 and activation of p38 MAPK/ NFκB signaling pathway in gastric cancer cells. J Biomed Sci (2014) 0.90
Inflammatory markers and bariatric surgery: a meta-analysis. Inflamm Res (2012) 0.90
Increased myocardial prevalence of C-reactive protein in human coronary heart disease: direct effects on microvessel density and endothelial cell survival. Cardiovasc Pathol (2012) 0.89
Association between lifestyle factors and plasma adiponectin levels in Japanese men. Lipids Health Dis (2005) 0.89
Plasma adiponectin concentration and its association with metabolic syndrome in patients with heart failure. Yonsei Med J (2012) 0.88
IGFBP-3 inhibits cytokine-induced insulin resistance and early manifestations of atherosclerosis. PLoS One (2013) 0.88
Determinants of adiponectin levels in patients with chronic systolic heart failure. Am J Cardiol (2010) 0.87
Eggs modulate the inflammatory response to carbohydrate restricted diets in overweight men. Nutr Metab (Lond) (2008) 0.87
Impact of physical inactivity on adipose tissue low-grade inflammation in first-degree relatives of type 2 diabetic patients. Diabetes Care (2011) 0.87
Adiponectin: an adipokine with protective features against metabolic syndrome. Iran J Basic Med Sci (2015) 0.87
Juvenile obesity aggravates disease severity in a rat model of atopic dermatitis. Allergy Asthma Immunol Res (2014) 0.86
Maternal visfatin concentration in normal pregnancy. J Perinat Med (2009) 0.86
Circulating levels of inflammatory markers in intrauterine growth restriction. Mediators Inflamm (2010) 0.86
C-reactive protein and cardiovascular disease in East asians: a systematic review. Clin Med Insights Cardiol (2015) 0.86
Inflammation and oxidative stress in obesity-related glomerulopathy. Int J Nephrol (2012) 0.85
Urinary proteins in children with urinary tract infection. Pediatr Nephrol (2009) 0.84
C-reactive protein in vulnerable coronary plaques. J Clin Pathol (2006) 0.84
Reductions in C-reactive protein in older adults with type 2 diabetes are related to improvements in body composition following a randomized controlled trial of resistance training. J Cachexia Sarcopenia Muscle (2014) 0.84
Adipose tissue and vascular inflammation in coronary artery disease. World J Cardiol (2014) 0.84
The role of novel biomarkers of cardiovascular disease in chronic kidney disease: focus on adiponectin and leptin. Curr Cardiol Rev (2008) 0.83
Adiponectin is associated with cardiovascular disease in male renal transplant recipients: baseline results from the LANDMARK 2 study. BMC Nephrol (2009) 0.82
Synergistic anti-inflammatory effect: simvastatin and pioglitazone reduce inflammatory markers of plasma and epicardial adipose tissue of coronary patients with metabolic syndrome. Diabetol Metab Syndr (2014) 0.82
Maternal serum adiponectin multimers in patients with a small-for-gestational-age newborn. J Perinat Med (2009) 0.82
Metabolic syndrome in peritoneal dialysis patients. NDT Plus (2008) 0.82
Roles of Reactive Oxygen Species on Insulin Resistance in Adipose Tissue. Diabetes Metab J (2016) 0.81
Glucose ingestion stimulates atherothrombotic inflammation in polycystic ovary syndrome. Am J Physiol Endocrinol Metab (2012) 0.81
High-intensity endurance training improves adiponectin mRNA and plasma concentrations. Eur J Appl Physiol (2011) 0.81
Serum total adiponectin is associated with impaired glucose tolerance in Asian Indian females but not in males. J Diabetes Sci Technol (2010) 0.81
Modulation of lupus phenotype by adiponectin deficiency in autoimmune mouse models. J Clin Immunol (2010) 0.80
A lower serum level of middle-molecular-weight adiponectin is a risk factor for endometrial cancer. Int J Clin Oncol (2013) 0.80
Hyperthyroidism-associated insulin resistance is not mediated by adiponectin levels. J Thyroid Res (2011) 0.79
Sources of CRP in atherosclerotic lesions. Am J Pathol (2006) 0.79
Association between markers of systemic inflammation, oxidative stress, lipid profiles, and insulin resistance in pregnant women. ARYA Atheroscler (2013) 0.79
Adiponectin levels are associated with the number and activity of circulating endothelial progenitor cells in patients with coronary artery disease. J Zhejiang Univ Sci B (2009) 0.79
Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet (2007) 9.56
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med (2002) 8.95
Retracted Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science (2004) 7.21
Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat Med (2005) 6.04
Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol (2003) 4.86
Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration. Nature (2010) 4.78
Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells. J Biol Chem (2003) 4.38
Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. Cell Stem Cell (2010) 4.21
Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity. Science (2010) 4.15
Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat Med (2004) 4.05
Obesity, adiponectin and vascular inflammatory disease. Curr Opin Lipidol (2003) 3.89
Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem (2003) 3.86
Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation (2002) 3.81
Adiponectin and metabolic syndrome. Arterioscler Thromb Vasc Biol (2003) 3.78
Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet (2002) 3.68
Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors. Nat Rev Cancer (2010) 3.48
Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes (2003) 3.28
Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin. Circ Res (2004) 3.16
Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem (2002) 3.05
Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of amp-activated protein kinase signaling. J Biol Chem (2004) 3.01
Inflammation in atherosclerosis: transition from theory to practice. Circ J (2010) 2.98
Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci U S A (2004) 2.85
The metabolic syndrome: a global public health problem and a new definition. J Atheroscler Thromb (2005) 2.77
Adiponectin inhibits the production of CXC receptor 3 chemokine ligands in macrophages and reduces T-lymphocyte recruitment in atherogenesis. Circ Res (2007) 2.66
Hypoadiponectinemia is an independent risk factor for hypertension. Hypertension (2004) 2.65
Budding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasome. Proc Natl Acad Sci U S A (2002) 2.63
Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages. Circulation (2004) 2.58
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology (2003) 2.53
Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein. Diabetes (2002) 2.49