Published in J Neuroinflammation on May 19, 2011
Consensus paper: pathological role of the cerebellum in autism. Cerebellum (2012) 2.32
Interleukin-6, a major cytokine in the central nervous system. Int J Biol Sci (2012) 2.01
Elevated maternal C-reactive protein and autism in a national birth cohort. Mol Psychiatry (2013) 1.38
Microglial activation - tuning and pruning adult neurogenesis. Front Pharmacol (2012) 1.29
Cytokine dysregulation in autism spectrum disorders (ASD): possible role of the environment. Neurotoxicol Teratol (2012) 1.21
Cytokine aberrations in autism spectrum disorder: a systematic review and meta-analysis. Mol Psychiatry (2014) 1.17
Immune mediators in the brain and peripheral tissues in autism spectrum disorder. Nat Rev Neurosci (2015) 1.13
Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism. Front Physiol (2014) 1.04
Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses. Front Mol Neurosci (2013) 1.04
Celecoxib as adjunctive treatment to risperidone in children with autistic disorder: a randomized, double-blind, placebo-controlled trial. Psychopharmacology (Berl) (2012) 1.03
Obesity and dementia: adipokines interact with the brain. Eur Neuropsychopharmacol (2014) 1.00
Microglia in the cerebral cortex in autism. J Autism Dev Disord (2012) 0.95
The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders. BMC Med (2015) 0.94
Inflammatory cytokines: potential biomarkers of immunologic dysfunction in autism spectrum disorders. Mediators Inflamm (2015) 0.91
Glia and neurodevelopment: focus on fetal alcohol spectrum disorders. Front Pediatr (2014) 0.91
IL-6 regulation of synaptic function in the CNS. Neuropharmacology (2014) 0.91
Therapeutic role of hematopoietic stem cells in autism spectrum disorder-related inflammation. Front Immunol (2013) 0.90
The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome. PLoS One (2012) 0.89
Cerebellum: links between development, developmental disorders and motor learning. Front Neuroanat (2012) 0.87
GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders. J Neuroinflammation (2014) 0.87
Lipid mediators in plasma of autism spectrum disorders. Lipids Health Dis (2012) 0.86
The Impact of Neuroimmune Alterations in Autism Spectrum Disorder. Front Psychiatry (2015) 0.86
Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6. Brain Behav Immun (2012) 0.84
Fetal programming of brain development: intrauterine stress and susceptibility to psychopathology. Sci Signal (2012) 0.84
Unraveling the mechanisms responsible for the comorbidity between metabolic syndrome and mental health disorders. Neuroendocrinology (2013) 0.83
Altered expression of Alzheimer's disease-related genes in the cerebellum of autistic patients: a model for disrupted brain connectome and therapy. Cell Death Dis (2014) 0.83
ZNF804A Transcriptional Networks in Differentiating Neurons Derived from Induced Pluripotent Stem Cells of Human Origin. PLoS One (2015) 0.83
Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation. Mol Psychiatry (2016) 0.82
Developmental neurotoxicity of inhaled ambient ultrafine particle air pollution: Parallels with neuropathological and behavioral features of autism and other neurodevelopmental disorders. Neurotoxicology (2015) 0.82
Identification and Treatment of Pathophysiological Comorbidities of Autism Spectrum Disorder to Achieve Optimal Outcomes. Clin Med Insights Pediatr (2016) 0.82
miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic Dysfunction. J Neurosci (2015) 0.81
Effect of topiramate on interleukin 6 expression in the hippocampus of amygdala-kindled epileptic rats. Exp Ther Med (2013) 0.80
Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder. J Neuroinflammation (2013) 0.80
Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders. Brain Behav Immun (2015) 0.79
Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota. Neural Plast (2016) 0.77
Relevance of Neuroinflammation and Encephalitis in Autism. Front Cell Neurosci (2016) 0.76
Astrocytes and Microglia and Their Potential Link with Autism Spectrum Disorders. Front Cell Neurosci (2016) 0.76
Increased astrocyte expression of IL-6 or CCL2 in transgenic mice alters levels of hippocampal and cerebellar proteins. Front Cell Neurosci (2014) 0.76
Beneficial Effects of a Protein Rich Diet on Coping Neurotrans-mitter Levels During Ampicillin-Induced Neurotoxicity Compared to Propionic-Acid Induced Autistic Biochemical Features. Int J Mol Cell Med (2016) 0.75
Evidence of Mitochondrial Dysfunction in Autism: Biochemical Links, Genetic-Based Associations, and Non-Energy-Related Mechanisms. Oxid Med Cell Longev (2017) 0.75
Neuroimaging endophenotypes in animal models of autism spectrum disorders: lost or found in translation? Psychopharmacology (Berl) (2013) 0.75
Maternal Immune Activation Causes Behavioral Impairments and Altered Cerebellar Cytokine and Synaptic Protein Expression. Neuropsychopharmacology (2017) 0.75
Association between Asthma and Autism Spectrum Disorder: A Meta-Analysis. PLoS One (2016) 0.75
Neuroimmune regulation of neurophysiology in the cerebellum. Cerebellum (2013) 0.75
The Immune System, Cytokines, and Biomarkers in Autism Spectrum Disorder. Neurosci Bull (2017) 0.75
Longitudinal association between early atopic dermatitis and subsequent attention-deficit or autistic disorder: A population-based case-control study. Medicine (Baltimore) (2016) 0.75
The placental interleukin-6 signaling controls fetal brain development and behavior. Brain Behav Immun (2016) 0.75
Additive effect of congenital heart disease and early developmental disorders on attention-deficit/hyperactivity disorder and autism spectrum disorder: a nationwide population-based longitudinal study. Eur Child Adolesc Psychiatry (2017) 0.75
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol (2007) 17.69
Advances in autism genetics: on the threshold of a new neurobiology. Nat Rev Genet (2008) 12.18
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nat Genet (2006) 11.14
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell (1991) 10.96
Neuroligins and neurexins link synaptic function to cognitive disease. Nature (2008) 9.23
Model of autism: increased ratio of excitation/inhibition in key neural systems. Genes Brain Behav (2003) 8.48
Interleukin-6: an overview. Annu Rev Immunol (1990) 7.48
Neuroglial activation and neuroinflammation in the brain of patients with autism. Ann Neurol (2005) 5.95
Disruption of neurexin 1 associated with autism spectrum disorder. Am J Hum Genet (2008) 5.04
Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer. J Leukoc Biol (2006) 3.45
Central nervous system neuronal migration. Annu Rev Neurosci (1999) 3.39
Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med (1994) 3.11
Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. J Neurosci (2003) 2.80
Immune proteins in brain development and synaptic plasticity. Neuron (2009) 2.72
Dynamic aspects of CNS synapse formation. Annu Rev Neurosci (2007) 2.47
Elevated immune response in the brain of autistic patients. J Neuroimmunol (2009) 2.46
Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6. J Neurosci (2002) 2.45
Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha. EMBO J (1996) 2.36
Elevated cytokine levels in children with autism spectrum disorder. J Neuroimmunol (2005) 1.85
Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism spectrum disorders and developmental regression. J Neuroimmunol (2001) 1.85
Interleukin-6 (IL-6)--a molecule with both beneficial and destructive potentials. Prog Neurobiol (1997) 1.83
Interleukin-6 expression and regulation in astrocytes. J Neuroimmunol (1999) 1.67
Physiological and pathological roles of interleukin-6 in the central nervous system. Mol Neurobiol (1997) 1.65
Neuronal migration mechanisms in development and disease. Curr Opin Neurobiol (2010) 1.64
Activation of the inflammatory response system in autism. Neuropsychobiology (2002) 1.56
Dendritic spine abnormalities in the occipital cortex of C57BL/6 Fmr1 knockout mice. Am J Med Genet B Neuropsychiatr Genet (2005) 1.55
Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms. J Neuroimmunol (2006) 1.53
Elevation of tumor necrosis factor-alpha in cerebrospinal fluid of autistic children. Pediatr Neurol (2007) 1.53
Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells. Eur J Neurosci (2007) 1.51
Do common variants play a role in risk for autism? Evidence and theoretical musings. Brain Res (2010) 1.44
Rac1 induces the clustering of AMPA receptors during spinogenesis. J Neurosci (2005) 1.43
DNA staining for fluorescence and laser confocal microscopy. J Histochem Cytochem (1997) 1.41
Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorder. Neuropsychobiology (2002) 1.40
Plasma increase of interleukin-12 and interferon-gamma. Pathological significance in autism. J Neuroimmunol (1996) 1.37
In vitro apoptosis in the human hepatoma cell line induced by transforming growth factor beta 1. Cancer Res (1992) 1.35
alpha3beta1 integrin modulates neuronal migration and placement during early stages of cerebral cortical development. Development (2004) 1.28
Netrin-1-alpha3beta1 integrin interactions regulate the migration of interneurons through the cortical marginal zone. Proc Natl Acad Sci U S A (2009) 1.26
Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells. Int J Cancer (1998) 1.26
Autism genetics: emerging data from genome-wide copy-number and single nucleotide polymorphism scans. Expert Rev Mol Diagn (2009) 1.22
Kinetics of plasma membrane and mitochondrial alterations in cells undergoing apoptosis. Cytometry (1995) 1.13
Growth factors and taurine protect against excitotoxicity by stabilizing calcium homeostasis and energy metabolism. J Neurosci (1999) 1.10
BDNF-Akt-Bcl2 antiapoptotic signaling pathway is compromised in the brain of autistic subjects. J Neurosci Res (2010) 1.07
Environmental signals influencing expression of the IFN-gamma receptor on human T cells control whether IFN-gamma promotes proliferation or apoptosis. J Immunol (1994) 1.06
Expression of inflammatory cytokines, Bcl2 and cathepsin D are altered in lymphoblasts of autistic subjects. Immunobiology (2010) 1.06
Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent. J Neurochem (1995) 1.05
Levels of Bcl-2 and P53 are altered in superior frontal and cerebellar cortices of autistic subjects. Cell Mol Neurobiol (2003) 1.03
TO-PRO-3 is an optimal fluorescent dye for nuclear counterstaining in dual-colour FISH on paraffin sections. Histochem Cell Biol (2001) 1.02
Mechanisms of ethanol-induced death of cerebellar granule cells. Cerebellum (2012) 0.95
Astrocyte-derived interleukin-6 promotes specific neuronal differentiation of neural progenitor cells from adult hippocampus. J Neurosci Res (2010) 0.91
Cathepsin D and apoptosis related proteins are elevated in the brain of autistic subjects. Neuroscience (2010) 0.89
Diacylglycerol kinase beta promotes dendritic outgrowth and spine maturation in developing hippocampal neurons. BMC Neurosci (2009) 0.86
Characterization of developing rat cortical neurons after epileptiform discharges. Int J Dev Neurosci (2010) 0.77
Abnormal cell properties and down-regulated FAK-Src complex signaling in B lymphoblasts of autistic subjects. Am J Pathol (2011) 0.77
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature (2003) 12.10
Genetic clonal diversity predicts progression to esophageal adenocarcinoma. Nat Genet (2006) 6.71
Fragile X premutation tremor/ataxia syndrome: molecular, clinical, and neuroimaging correlates. Am J Hum Genet (2003) 5.51
High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases. Proc Natl Acad Sci U S A (2010) 4.78
Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase. J Biol Chem (2004) 3.79
Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis. Nat Rev Cancer (2010) 3.27
Extent of low-grade dysplasia is a risk factor for the development of esophageal adenocarcinoma in Barrett's esophagus. Am J Gastroenterol (2007) 3.00
Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell (2008) 2.84
An IAP-IAP complex inhibits apoptosis. J Biol Chem (2004) 2.82
Maternal malaria and gravidity interact to modify infant susceptibility to malaria. PLoS Med (2005) 2.72
Expansion of the fragile X CGG repeat in females with premutation or intermediate alleles. Am J Hum Genet (2003) 2.71
Fragile X premutation carriers: characteristic MR imaging findings of adult male patients with progressive cerebellar and cognitive dysfunction. AJNR Am J Neuroradiol (2002) 2.58
HBXIP functions as a cofactor of survivin in apoptosis suppression. EMBO J (2003) 2.47
Elevated immune response in the brain of autistic patients. J Neuroimmunol (2009) 2.46
The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes. Acta Neuropathol (2010) 2.42
Leukocyte telomere length predicts cancer risk in Barrett's esophagus. Cancer Epidemiol Biomarkers Prev (2007) 2.39
Transcription activator-like effector nucleases enable efficient plant genome engineering. Plant Physiol (2012) 2.36
NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma. PLoS Med (2007) 2.23
Gene expression analyzed by high-resolution state array analysis and quantitative proteomics: response of yeast to mating pheromone. Mol Cell Proteomics (2004) 2.22
Selectively advantageous mutations and hitchhikers in neoplasms: p16 lesions are selected in Barrett's esophagus. Cancer Res (2004) 2.15
Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer. J Med Chem (2004) 2.05
Analysis of inflammatory cytokines in the tears of dry eye patients. Cornea (2009) 1.96
Structure of a c-kit product complex reveals the basis for kinase transactivation. J Biol Chem (2003) 1.95
A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma. Cancer Prev Res (Phila) (2010) 1.89
Long non-coding RNA HOTAIR is an independent prognostic marker for nasopharyngeal carcinoma progression and survival. Cancer Sci (2013) 1.88
The combination of genetic instability and clonal expansion predicts progression to esophageal adenocarcinoma. Cancer Res (2004) 1.76
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands. Proc Natl Acad Sci U S A (2010) 1.73
A likelihood-based approach to mixed modeling with ambiguity in cluster identifiers. Biostatistics (2008) 1.72
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response. Proc Natl Acad Sci U S A (2009) 1.69
Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 protein. J Biol Chem (2011) 1.61
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proc Natl Acad Sci U S A (2011) 1.59
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells. Proc Natl Acad Sci U S A (2010) 1.55
Decreased GABA(A) receptor expression in the seizure-prone fragile X mouse. Neurosci Lett (2004) 1.55
Retracted Alteration of astrocytes and Wnt/β-catenin signaling in the frontal cortex of autistic subjects. J Neuroinflammation (2012) 1.51
Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling. Hum Mol Genet (2006) 1.48
Fragile X prenatal analyses show full mutation females at high risk for mosaic Turner syndrome: fragile X leads to chromosome loss. Am J Med Genet A (2009) 1.48
Oxidative stress in autism: increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferrin--the antioxidant proteins. Life Sci (2004) 1.44
Alginate production by Pseudomonas putida creates a hydrated microenvironment and contributes to biofilm architecture and stress tolerance under water-limiting conditions. J Bacteriol (2007) 1.41
An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence. Nat Immunol (2010) 1.39
Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity. Cancer Res (2008) 1.36
Electrospun fibrous mats with high porosity as potential scaffolds for skin tissue engineering. Biomacromolecules (2008) 1.31
Synthesis and characterization of biocompatible Fe3O4 nanoparticles. J Biomed Mater Res A (2007) 1.28
ENU-induced phenovariance in mice: inferences from 587 mutations. BMC Res Notes (2012) 1.28
Preventable maternal mortality: geographic/rural-urban differences and associated factors from the population-based Maternal Mortality Surveillance System in China. BMC Public Health (2011) 1.27
Autism spectrum disorder in children and adolescents with fragile X syndrome: within-syndrome differences and age-related changes. Am J Intellect Dev Disabil (2010) 1.27
Increasing genomic instability during premalignant neoplastic progression revealed through high resolution array-CGH. Genes Chromosomes Cancer (2007) 1.26
Mutations in the gene DNAJC5 cause autosomal dominant Kufs disease in a proportion of cases: study of the Parry family and 8 other families. PLoS One (2012) 1.25
Fragile X analysis of 1112 prenatal samples from 1991 to 2010. Prenat Diagn (2011) 1.23
Geographical detector-based risk assessment of the under-five mortality in the 2008 Wenchuan earthquake, China. PLoS One (2011) 1.22
Prediction of conformational B-cell epitopes from 3D structures by random forests with a distance-based feature. BMC Bioinformatics (2011) 1.20
Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions. J Clin Invest (2006) 1.20
Erk1 positively regulates osteoclast differentiation and bone resorptive activity. PLoS One (2011) 1.19
Fragile X AGG analysis provides new risk predictions for 45-69 repeat alleles. Am J Med Genet A (2013) 1.19
Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure. Int J Cardiol (2008) 1.19
A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity. Proc Natl Acad Sci U S A (2012) 1.19
Multiple increased osteoclast functions in individuals with neurofibromatosis type 1. Am J Med Genet A (2011) 1.18
Role for stromal heterogeneity in prostate tumorigenesis. Cancer Res (2011) 1.18
Maternal mortality in China, 1996-2005. Int J Gynaecol Obstet (2010) 1.18
Chromosomal instability and copy number alterations in Barrett's esophagus and esophageal adenocarcinoma. Clin Cancer Res (2009) 1.17
Neuropsychiatric symptoms of fragile X syndrome: pathophysiology and pharmacotherapy. CNS Drugs (2004) 1.14
Chromosomal instability in Barrett's esophagus is related to telomere shortening. Cancer Epidemiol Biomarkers Prev (2006) 1.12
Effects of sampling context on spontaneous expressive language in males with fragile X syndrome or Down syndrome. J Speech Lang Hear Res (2012) 1.11
The changes in maternal mortality in 1000 counties in mid-Western China by a government-initiated intervention. PLoS One (2012) 1.09
iRhom2 is required for the secretion of mouse TNFα. Blood (2012) 1.08
Mental retardation linked to mutations in the HSD17B10 gene interfering with neurosteroid and isoleucine metabolism. Proc Natl Acad Sci U S A (2009) 1.08
Knockdown of Oct4 and Nanog expression inhibits the stemness of pancreatic cancer cells. Cancer Lett (2013) 1.08
Bone marrow derived mesenchymal stem cells incorporate into the prostate during regrowth. PLoS One (2010) 1.07
Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells. Hum Mol Genet (2006) 1.07
BDNF-Akt-Bcl2 antiapoptotic signaling pathway is compromised in the brain of autistic subjects. J Neurosci Res (2010) 1.07
Investigation of drug release and matrix degradation of electrospun poly(DL-lactide) fibers with paracetanol inoculation. Biomacromolecules (2006) 1.07
Hydroxyapatite nucleation and growth mechanism on electrospun fibers functionalized with different chemical groups and their combinations. Biomaterials (2010) 1.06
Expression of inflammatory cytokines, Bcl2 and cathepsin D are altered in lymphoblasts of autistic subjects. Immunobiology (2010) 1.06
Twenty-five cases of adult prostate sarcoma treated at a high-volume institution from 1989 to 2009. Urology (2013) 1.05
Geographical disparities of infant mortality in rural China. Arch Dis Child Fetal Neonatal Ed (2012) 1.05
Household catastrophic medical expenses in eastern China: determinants and policy implications. BMC Health Serv Res (2013) 1.05
Preparation and characterization of a novel electrospun spider silk fibroin/poly(D,L-lactide) composite fiber. J Phys Chem B (2008) 1.04
Stable knockdown of polycystin-1 confers integrin-alpha2beta1-mediated anoikis resistance. J Am Soc Nephrol (2006) 1.03
Inhibition of HER-2(neu/ErbB2) restores normal function and structure to polycystic kidney disease (PKD) epithelia. Biochim Biophys Acta (2006) 1.03
Genes associated with autism spectrum disorder. Brain Res Bull (2012) 1.03
Promotion of skin regeneration in diabetic rats by electrospun core-sheath fibers loaded with basic fibroblast growth factor. Biomaterials (2011) 1.02
Neonatal mortality due to preterm birth at 28-36 weeks' gestation in China, 2003-2008. Paediatr Perinat Epidemiol (2011) 1.01
MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell. BMC Cancer (2014) 0.99
Yes-associated protein expression in head and neck squamous cell carcinoma nodal metastasis. PLoS One (2011) 0.99
Osteoblast function on electrically conductive electrospun PLA/MWCNTs nanofibers. Biomaterials (2011) 0.99
Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors. Biochim Biophys Acta (2012) 0.98
Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1. Hum Mol Genet (2007) 0.98
NSAIDs modulate clonal evolution in Barrett's esophagus. PLoS Genet (2013) 0.98