Matthew K Topham

Author PubWeight™ 53.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Disruption of diacylglycerol metabolism impairs the induction of T cell anergy. Nat Immunol 2006 2.43
2 Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins. Science 2007 2.25
3 Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance. Cell 2008 1.97
4 DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN. J Am Soc Nephrol 2012 1.93
5 Regulation and functions of diacylglycerol kinases. Chem Rev 2011 1.48
6 Differential trafficking of the vesicular monoamine transporter-2 by methamphetamine and cocaine. Eur J Pharmacol 2002 1.30
7 Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI. Mol Biol Cell 2009 1.28
8 Diacylglycerol kinases. Cell Signal 2004 1.25
9 Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling. Proc Natl Acad Sci U S A 2005 1.21
10 Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling. Proc Natl Acad Sci U S A 2006 1.20
11 Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta. J Biol Chem 2002 1.20
12 Association of diacylglycerol kinase zeta with protein kinase C alpha: spatial regulation of diacylglycerol signaling. J Cell Biol 2003 1.11
13 Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol. J Biol Chem 2009 1.10
14 Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein. J Biol Chem 2008 1.08
15 Dramatic differences in the roles in lipid metabolism of two isoforms of diacylglycerol kinase. Biochemistry 2008 1.08
16 Expression of Long-chain Fatty Acyl-CoA Synthetase 4 in Breast and Prostate Cancers Is Associated with Sex Steroid Hormone Receptor Negativity. Transl Oncol 2010 1.08
17 Diacylglycerol kinase zeta regulates phosphatidylinositol 4-phosphate 5-kinase Ialpha by a novel mechanism. Cell Signal 2004 1.00
18 Protein kinase C alpha phosphorylates and negatively regulates diacylglycerol kinase zeta. J Biol Chem 2003 1.00
19 Diacylglycerol kinases as sources of phosphatidic acid. Biochim Biophys Acta 2009 0.99
20 Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance. EMBO J 2009 0.98
21 Diacylglycerol kinase-zeta localization in skeletal muscle is regulated by phosphorylation and interaction with syntrophins. Mol Biol Cell 2003 0.98
22 Transgenic expression of cyclooxygenase-2 in mouse intestine epithelium is insufficient to initiate tumorigenesis but promotes tumor progression. Cancer Lett 2008 0.97
23 Regulation of neurite outgrowth in N1E-115 cells through PDZ-mediated recruitment of diacylglycerol kinase zeta. Mol Cell Biol 2005 0.95
24 Role of the hydrophobic segment of diacylglycerol kinase epsilon. Biochemistry 2007 0.95
25 DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J 2010 0.94
26 Determination of the topology of the hydrophobic segment of mammalian diacylglycerol kinase epsilon in a cell membrane and its relationship to predictions from modeling. J Mol Biol 2008 0.94
27 The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta. J Biol Chem 2005 0.91
28 Cyclooxygenase-2 transactivates the epidermal growth factor receptor through specific E-prostanoid receptors and tumor necrosis factor-alpha converting enzyme. Cell Signal 2007 0.91
29 Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase. Biochemistry 2007 0.91
30 Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8. J Biol Chem 2010 0.87
31 Measurement of mammalian diacylglycerol kinase activity in vitro and in cells. Methods Enzymol 2007 0.86
32 Study of arachidonoyl specificity in two enzymes of the PI cycle. J Mol Biol 2011 0.86
33 Lipid modulation of the activity of diacylglycerol kinase alpha- and zeta-isoforms: activation by phosphatidylethanolamine and cholesterol. Biochemistry 2004 0.85
34 The levels of retinoic acid-inducible gene I are regulated by heat shock protein 90-alpha. J Immunol 2009 0.85
35 Deficiency of phospholipase A2 group 7 decreases intestinal polyposis and colon tumorigenesis in Apc(Min/+) mice. Cancer Res 2013 0.84
36 Diacylglycerol kinase delta promotes lipogenesis. Biochemistry 2013 0.84
37 Molecular species of phosphatidylinositol-cycle intermediates in the endoplasmic reticulum and plasma membrane. Biochemistry 2010 0.83
38 Phosphatidylinositol-4-phosphate 5-kinase isoforms exhibit acyl chain selectivity for both substrate and lipid activator. J Biol Chem 2012 0.83
39 Substrate specificity of diacylglycerol kinase-epsilon and the phosphatidylinositol cycle. FEBS Lett 2011 0.83
40 DGKζ is involved in LPS-activated phagocytosis through IQGAP1/Rac1 pathway. Biochem Biophys Res Commun 2012 0.82
41 Membrane interactions of the hydrophobic segment of diacylglycerol kinase epsilon. Biochim Biophys Acta 2007 0.82
42 Ceramide-induced alterations in dopamine transporter function. Eur J Pharmacol 2003 0.82
43 Cytoplasmic localization of DGKζ exerts a protective effect against p53-mediated cytotoxicity. J Cell Sci 2013 0.81
44 The alpha isoform of diacylglycerol kinase exhibits arachidonoyl specificity with alkylacylglycerol. Biochemistry 2004 0.81
45 Diacylglycerol kinase δ modulates Akt phosphorylation through pleckstrin homology domain leucine-rich repeat protein phosphatase 2 (PHLPP2). J Biol Chem 2012 0.80
46 Regulation of sonic hedgehog expression by integrin β1 and epidermal growth factor receptor in intestinal epithelium. IUBMB Life 2014 0.79
47 Protein kinase C inhibits binding of diacylglycerol kinase-zeta to the retinoblastoma protein. Biochim Biophys Acta 2006 0.78
48 Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-ε expression. J Immunol 2013 0.77
49 Endocannabinoids and diacylglycerol kinase activity. Biochim Biophys Acta 2010 0.77
50 DGKζ is degraded through the cytoplasmic ubiquitin-proteasome system under excitotoxic conditions, which causes neuronal apoptosis because of aberrant cell cycle reentry. Cell Signal 2012 0.76
51 DGKζ under stress conditions: “to be nuclear or cytoplasmic, that is the question”. Adv Biol Regul 2014 0.76
52 The basis of the substrate specificity of the epsilon isoform of human diacylglycerol kinase is not a consequence of competing hydrolysis of ATP. Chem Phys Lipids 2012 0.76
53 Novel mechanism for regulation of plasma platelet-activating factor acetylhydrolase expression in mammalian cells. Biochem J 2010 0.76