Published in RNA on June 01, 2005
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res (2010) 3.21
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther (2009) 2.92
Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer. Autophagy (2010) 2.62
Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines. Immunity (2013) 2.08
A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome. EMBO J (2010) 1.74
Optimizing electroporation conditions in primary and other difficult-to-transfect cells. J Biomol Tech (2008) 1.24
Human ERAL1 is a mitochondrial RNA chaperone involved in the assembly of the 28S small mitochondrial ribosomal subunit. Biochem J (2010) 1.18
Mechanisms for the intracellular manipulation of organelles by conventional electroporation. Biophys J (2010) 1.06
GLO1-A novel amplified gene in human cancer. Genes Chromosomes Cancer (2010) 0.99
REXO2 is an oligoribonuclease active in human mitochondria. PLoS One (2013) 0.88
Efficient, high-throughput transfection of human embryonic stem cells. Stem Cell Res Ther (2010) 0.87
Lipid droplet-associated proteins protect renal tubular cells from fatty acid-induced apoptosis. Am J Pathol (2008) 0.86
The EGFR/ErbB3 Pathway Acts as a Compensatory Survival Mechanism upon c-Met Inhibition in Human c-Met+ Hepatocellular Carcinoma. PLoS One (2015) 0.84
Electroporation Knows No Boundaries: The Use of Electrostimulation for siRNA Delivery in Cells and Tissues. J Biomol Screen (2015) 0.84
Genome-wide RNAi high-throughput screen identifies proteins necessary for the AHR-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci (2013) 0.79
Lipid nanoparticles as carriers for RNAi against viral infections: current status and future perspectives. Biomed Res Int (2014) 0.79
Site-specific gene transfer with high efficiency onto a carbon nanotube-loaded electrode. J R Soc Interface (2008) 0.78
Transcriptional network predicts viral set point during acute HIV-1 infection. J Am Med Inform Assoc (2012) 0.77
Target gene abundance contributes to the efficiency of siRNA-mediated gene silencing. Nucleic Acid Ther (2014) 0.76
Miniaturization of gene transfection assays in 384- and 1536-well microplates. Anal Biochem (2014) 0.75
Voltage Preconditioning Allows Modulated Gene Expression in Neurons Using PEI-complexed siRNA. Mol Ther Nucleic Acids (2013) 0.75
A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury. J Biol Chem (2016) 0.75
Optimal Electroporation Condition for Small Interfering RNA Transfection into MDA-MB-468 Cell Line. Iran J Med Sci (2012) 0.75
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 72.56
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 57.23
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature (2000) 23.17
Electroporation for the efficient transfection of mammalian cells with DNA. Nucleic Acids Res (1987) 12.80
A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature (2004) 8.67
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc Natl Acad Sci U S A (2001) 7.12
Identification of essential genes in cultured mammalian cells using small interfering RNAs. J Cell Sci (2001) 6.66
A functional genomic analysis of cell morphology using RNA interference. J Biol (2003) 5.99
Microarrays of cells expressing defined cDNAs. Nature (2001) 5.05
Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science (2003) 3.63
Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells. Mol Biol Cell (2002) 3.13
Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing. Proc Natl Acad Sci U S A (2003) 3.03
Electroporation: theory and methods, perspectives for drug delivery, gene therapy and research. Acta Physiol Scand (2003) 2.75
Noise amidst the silence: off-target effects of siRNAs? Trends Genet (2004) 2.38
Association of cdk2 kinase with the transcription factor E2F during S phase. Science (1992) 2.37
Progress and prospects: naked DNA gene transfer and therapy. Gene Ther (2003) 2.00
RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells. Proc Natl Acad Sci U S A (2003) 1.84
Targeting the kinesin Eg5 to monitor siRNA transfection in mammalian cells. Biotechniques (2002) 1.52
RNA-interference-based functional genomics in mammalian cells: reverse genetics coming of age. Oncogene (2004) 1.40
Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila. Microbes Infect (2003) 1.32
The p34cdc2-related cyclin-dependent kinase 11 interacts with the p47 subunit of eukaryotic initiation factor 3 during apoptosis. J Biol Chem (2002) 1.29
Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle. Mol Biol Cell (2004) 1.22
The effectiveness of double-stranded short inhibitory RNAs (siRNAs) may depend on the method of transfection. Antisense Nucleic Acid Drug Dev (2002) 1.11
Transient RNA interference in hematopoietic progenitors with functional consequences. Genesis (2003) 1.03
RNA interference shows critical requirement for NF-kappa B p50 in the production of IL-12 by human dendritic cells. J Immunol (2003) 0.97
Surfection: a new platform for transfected cell arrays. Nucleic Acids Res (2004) 0.97
Resveratrol-induced G2 arrest through the inhibition of CDK7 and p34CDC2 kinases in colon carcinoma HT29 cells. Biochem Pharmacol (2003) 0.95
Improved siRNA-mediated silencing in refractory adherent cell lines by detachment and transfection in suspension. Biotechniques (2004) 0.94
Microarray transfection analysis of transcriptional regulation by cAMP-dependent protein kinase. Mol Cell Proteomics (2004) 0.92
Oncology studies using siRNA libraries: the dawn of RNAi-based genomics. Oncogene (2004) 0.90
Identification and characterization of the human Cdc2l2 gene promoter. Gene (2004) 0.90
The apparent uptake of fluorescently labeled siRNAs by electroporated cells depends on the fluorochrome. Oligonucleotides (2003) 0.87
High-voltage and high-salt buffer facilitates electroporation of human aortic smooth-muscle cells. Biotechniques (1998) 0.79
High-throughput siRNA-based functional target validation. J Biomol Screen (2004) 0.79
RAS is regulated by the let-7 microRNA family. Cell (2005) 30.24
The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res (2007) 9.32
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med (2011) 6.85
Dominant and diet-responsive groups of bacteria within the human colonic microbiota. ISME J (2010) 5.43
Increase in viral gastroenteritis outbreaks in Europe and epidemic spread of new norovirus variant. Lancet (2004) 5.25
The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle (2008) 4.95
Recent epidemic of acute hepatitis C virus in HIV-positive men who have sex with men linked to high-risk sexual behaviours. AIDS (2007) 4.40
Surgical treatment of permanent diaphragm paralysis after interscalene nerve block for shoulder surgery. Anesthesiology (2013) 4.25
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J Alzheimers Dis (2008) 3.84
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res (2010) 3.21
An optimized isolation and labeling platform for accurate microRNA expression profiling. RNA (2005) 3.12
Isoniazid's bactericidal activity ceases because of the emergence of resistance, not depletion of Mycobacterium tuberculosis in the log phase of growth. J Infect Dis (2006) 3.04
Herpes simplex virus type 2 infection increases HIV incidence: a prospective study in rural Tanzania. AIDS (2002) 2.93
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther (2009) 2.92
Viral gastroenteritis outbreaks in Europe, 1995-2000. Emerg Infect Dis (2003) 2.79
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice. Mol Ther (2011) 2.75
The promise of microRNA replacement therapy. Cancer Res (2010) 2.68
Sufficiently important difference: expanding the framework of clinical significance. Med Decis Making (2005) 2.65
Hunting for consensus: reconciling bushmeat harvest, conservation, and development policy in West and Central Africa. Conserv Biol (2007) 2.50
Validity of the alcohol use disorders identification test in college students. Alcohol Clin Exp Res (2004) 2.30
Longitudinal analysis of CD8+ T cells specific for structural and nonstructural hepatitis B virus proteins in patients with chronic hepatitis B: implications for immunotherapy. J Virol (2004) 2.28
Molecular epidemiology of human enterovirus 71 in the United Kingdom from 1998 to 2006. J Clin Microbiol (2008) 2.24
International collaborative study to compare reverse transcriptase PCR assays for detection and genotyping of noroviruses. J Clin Microbiol (2003) 2.23
Diagnostic reverse-transcription polymerase chain reaction kit for filoviruses based on the strain collections of all European biosafety level 4 laboratories. J Infect Dis (2007) 2.22
A randomized, controlled trial of an aerosolized vaccine against measles. N Engl J Med (2015) 2.16
Evidence of a large, international network of HCV transmission in HIV-positive men who have sex with men. Gastroenterology (2009) 2.10
Diagnosing norovirus-associated infectious intestinal disease using viral load. BMC Infect Dis (2009) 2.09
Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity. Inhal Toxicol (2007) 2.06
Global distribution of measles genotypes and measles molecular epidemiology. J Infect Dis (2011) 2.03
Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations. Antimicrob Agents Chemother (2007) 2.02
The pulmonary toxicology of ultrafine particles. J Aerosol Med (2002) 2.02
Temporal analysis of early immune responses in patients with acute hepatitis B virus infection. Gastroenterology (2009) 1.88
Mumps outbreaks across England and Wales in 2004: observational study. BMJ (2005) 1.87
Community incidence of norovirus-associated infectious intestinal disease in England: improved estimates using viral load for norovirus diagnosis. Am J Epidemiol (2010) 1.86
Genome-scale microRNA and small interfering RNA screens identify small RNA modulators of TRAIL-induced apoptosis pathway. Cancer Res (2007) 1.83
Personalized exposure assessment: promising approaches for human environmental health research. Environ Health Perspect (2005) 1.83
Vaccine effectiveness estimates, 2004-2005 mumps outbreak, England. Emerg Infect Dis (2007) 1.79
Early identification of common-source foodborne virus outbreaks in Europe. Emerg Infect Dis (2003) 1.75
Dendrodendritic inhibition and simulated odor responses in a detailed olfactory bulb network model. J Neurophysiol (2003) 1.72
Human papillomavirus cofactors by disease progression and human papillomavirus types in the study to understand cervical cancer early endpoints and determinants. Cancer Epidemiol Biomarkers Prev (2009) 1.70
A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine. Crit Care Med (2012) 1.69
Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection. J Exp Med (2002) 1.66
Phenoxodiol--an isoflavone analog--induces apoptosis in chemoresistant ovarian cancer cells. Oncogene (2003) 1.65
Improving the care of patients with regard to chemotherapy-induced nausea and emesis: the effect of feedback to clinicians on adherence to antiemetic prescribing guidelines. J Clin Oncol (2003) 1.64
Diagnosing rotavirus A associated IID: Using ELISA to identify a cut-off for real time RT-PCR. J Clin Virol (2009) 1.59
Apoptosis in Parkinson's disease: signals for neuronal degradation. Ann Neurol (2003) 1.55
Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7. Cancer Res (2012) 1.55
Oxymetazoline adds to the effectiveness of fluticasone furoate in the treatment of perennial allergic rhinitis. J Allergy Clin Immunol (2011) 1.49
United States feasibility study of transcatheter insertion of a stented aortic valve by the left ventricular apex. Ann Thorac Surg (2008) 1.47
Pharmacodynamics of β-lactamase inhibition by NXL104 in combination with ceftaroline: examining organisms with multiple types of β-lactamases. Antimicrob Agents Chemother (2011) 1.46
Learning to work together: developing academic and community research partnerships. WMJ (2004) 1.45
Randomized trial of surgical cutdown versus percutaneous access in transfemoral TAVR. Catheter Cardiovasc Interv (2013) 1.45
Toric Implantable Collamer Lens for moderate to high myopic astigmatism. Ophthalmology (2007) 1.45
Indigenous hepatitis E virus infection in England: more common than it seems. J Clin Virol (2009) 1.44
Serum microRNA biomarkers for detection of non-small cell lung cancer. PLoS One (2012) 1.43
Monte Carlo simulation of an x-ray volume imaging cone beam CT unit. Med Phys (2009) 1.42
The elimination of indigenous measles transmission in England and Wales. J Infect Dis (2003) 1.42
Incidence and risk factors of paediatric rotavirus diarrhoea in northern Ghana. Trop Med Int Health (2003) 1.42
Survey of select practice behaviors by primary care physicians on the use of opioids for chronic pain. Curr Med Res Opin (2006) 1.41
Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation. Mol Cancer Ther (2003) 1.41
Characterization of G10P[11] rotaviruses causing acute gastroenteritis in neonates and infants in Vellore, India. J Clin Microbiol (2004) 1.41
Reliability of risk algorithms in predicting early and late operative outcomes in high-risk patients undergoing aortic valve replacement. J Thorac Cardiovasc Surg (2007) 1.40
Tracheary element differentiation. Annu Rev Plant Biol (2007) 1.39
H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa. Genome Res (2015) 1.39
Early qualitative risk assessment of the emerging zoonotic potential of animal diseases. BMJ (2005) 1.38
Olden times: looking back on a career at the NIEHS. Environ Health Perspect (2004) 1.38
Ranibizumab for choroidal neovascularization secondary to causes other than age-related macular degeneration: a phase I clinical trial. Ophthalmology (2010) 1.32
Brief physician advice for heavy drinking college students: a randomized controlled trial in college health clinics. J Stud Alcohol Drugs (2010) 1.30
Thermostable group II intron reverse transcriptase fusion proteins and their use in cDNA synthesis and next-generation RNA sequencing. RNA (2013) 1.29
Targeting the mitochondria activates two independent cell death pathways in ovarian cancer stem cells. Mol Cancer Ther (2011) 1.28
miR-10a overexpression is associated with NPM1 mutations and MDM4 downregulation in intermediate-risk acute myeloid leukemia. Exp Hematol (2011) 1.27
Molecular mechanism of phenoxodiol-induced apoptosis in ovarian carcinoma cells. Cancer (2006) 1.27
Cigarette smoking and associated health risks among students at five universities. Nicotine Tob Res (2009) 1.26
Risk factors associated with human infection during the 2006 West Nile virus outbreak in Davis, a residential community in northern California. Am J Trop Med Hyg (2008) 1.24
Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS. Oncogene (2005) 1.23
Changing patterns of rotavirus genotypes in ghana: emergence of human rotavirus G9 as a major cause of diarrhea in children. J Clin Microbiol (2003) 1.23
Development of the Global Measles Laboratory Network. J Infect Dis (2003) 1.20
Strategies for setting a national research agenda that is responsive to community needs. Environ Health Perspect (2003) 1.19
Constructs of health and environment inform child obesity prevention in American Indian communities. Obesity (Silver Spring) (2008) 1.19
Community prevalence of antibodies to human immunodeficiency virus in rural and urban Vellore, Tamil Nadu. Natl Med J India (2005) 1.18
Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. Bioorg Med Chem Lett (2008) 1.16
The astrocyte/meningeal cell interface is a barrier to neurite outgrowth which can be overcome by manipulation of inhibitory molecules or axonal signalling pathways. Mol Cell Neurosci (2003) 1.16
Hormone receptors and proliferation in breast carcinomas of equivalent histologic grades in pre- and postmenopausal women. Int J Cancer (2002) 1.14
Creating an antibacterial with in vivo efficacy: synthesis and characterization of potent inhibitors of the bacterial cell division protein FtsZ with improved pharmaceutical properties. J Med Chem (2010) 1.13
Reproductive tract infections: prevalence and risk factors in rural Bangladesh. Bull World Health Organ (2002) 1.13
Depression and suicide ideation among students accessing campus health care. Am J Orthopsychiatry (2011) 1.11
A cross-sectional survey of herbal remedy taking by United Arab Emirate (UAE) citizens in Abu Dhabi. Pharmacoepidemiol Drug Saf (2008) 1.11
Impact of aerial spraying of pyrethrin insecticide on Culex pipiens and Culex tarsalis (Diptera: Culicidae) abundance and West Nile virus infection rates in an urban/suburban area of Sacramento County, California. J Med Entomol (2008) 1.10
Participatory photo mapping (PPM): exploring an integrated method for health and place research with young people. Health Place (2008) 1.10
Cost-minimization analysis of the direct costs of TPE and IVIg in the treatment of Guillain-Barré syndrome. BMC Health Serv Res (2011) 1.09
Resistance emergence mechanism and mechanism of resistance suppression by tobramycin for cefepime for Pseudomonas aeruginosa. Antimicrob Agents Chemother (2011) 1.09