Published in Oncogene on March 17, 2005
Neutrophil gelatinase-associated lipocalin as a survival factor. Biochem J (2005) 1.80
FoxO1 is a positive regulator of bone formation by favoring protein synthesis and resistance to oxidative stress in osteoblasts. Cell Metab (2010) 1.72
Mutual dependence of Foxo3a and PGC-1alpha in the induction of oxidative stress genes. J Biol Chem (2009) 1.40
FOXO3a promotes tumor cell invasion through the induction of matrix metalloproteinases. Mol Cell Biol (2009) 1.35
Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival. PLoS One (2007) 1.32
Fenofibrate-induced nuclear translocation of FoxO3A triggers Bim-mediated apoptosis in glioblastoma cells in vitro. Cell Cycle (2012) 1.23
FoxO3a and disease progression. World J Biol Chem (2014) 1.05
Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway. Carcinogenesis (2013) 1.01
Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim. Infect Immun (2008) 0.99
Maintenance of manganese superoxide dismutase (SOD2)-mediated delayed radioprotection induced by repeated administration of the free thiol form of amifostine. Radiat Res (2008) 0.98
SOD3 decreases ischemic injury derived apoptosis through phosphorylation of Erk1/2, Akt, and FoxO3a. PLoS One (2011) 0.96
Restoration of mitochondria function as a target for cancer therapy. Drug Discov Today (2015) 0.93
Manganese superoxide dismutase interacts with a large scale of cellular and mitochondrial proteins in low-dose radiation-induced adaptive radioprotection. Free Radic Biol Med (2012) 0.92
Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker. J Clin Invest (2012) 0.92
Bim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer. J Biol Chem (2012) 0.91
FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas. PLoS One (2013) 0.90
Mitochondrial and postmitochondrial survival signaling in cancer. Mitochondrion (2013) 0.90
High glucose induced oxidative stress and apoptosis in cardiac microvascular endothelial cells are regulated by FoxO3a. PLoS One (2013) 0.85
Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation. Oncogene (2010) 0.85
Insulin-like growth factor-I-forkhead box O transcription factor 3a counteracts high glucose/tumor necrosis factor-α-mediated neuronal damage: implications for human immunodeficiency virus encephalitis. J Neurosci Res (2010) 0.83
Sp1 is involved in H2O2-induced PUMA gene expression and apoptosis in colorectal cancer cells. J Exp Clin Cancer Res (2008) 0.78
Dihydroartemisinin and its derivative induce apoptosis in acute myeloid leukemia through Noxa-mediated pathway requiring iron and endoperoxide moiety. Oncotarget (2015) 0.77
Alteration of Aging-Dependent MicroRNAs in Idiopathic Pulmonary Fibrosis. Drug Dev Res (2015) 0.76
Molecular regulatory mechanisms of osteoclastogenesis through cytoprotective enzymes. Redox Biol (2016) 0.76
NFκB1 (p50) suppresses SOD2 expression by inhibiting FoxO3a transactivation in a miR190/PHLPP1/Akt-dependent axis. Mol Biol Cell (2013) 0.76
Pathways that Regulate ROS Scavenging Enzymes, and Their Role in Defense Against Tissue Destruction in Periodontitis. Front Physiol (2017) 0.75
Functional block of IL-17 cytokine promotes bone healing by augmenting FOXO1 and ATF4 activity in cortical bone defect model. Osteoporos Int (2017) 0.75
RAS is regulated by the let-7 microRNA family. Cell (2005) 30.24
The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res (2007) 9.32
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature (2002) 7.88
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med (2011) 6.85
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic. Cancer Res (2005) 5.87
Dominant and diet-responsive groups of bacteria within the human colonic microbiota. ISME J (2010) 5.43
Increase in viral gastroenteritis outbreaks in Europe and epidemic spread of new norovirus variant. Lancet (2004) 5.25
The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle (2008) 4.95
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. J Immunol (2002) 4.85
Recent epidemic of acute hepatitis C virus in HIV-positive men who have sex with men linked to high-risk sexual behaviours. AIDS (2007) 4.40
FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J Cell Biol (2003) 4.31
Surgical treatment of permanent diaphragm paralysis after interscalene nerve block for shoulder surgery. Anesthesiology (2013) 4.25
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J Alzheimers Dis (2008) 3.84
FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. J Biol Chem (2003) 3.41
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res (2010) 3.21
An optimized isolation and labeling platform for accurate microRNA expression profiling. RNA (2005) 3.12
Isoniazid's bactericidal activity ceases because of the emergence of resistance, not depletion of Mycobacterium tuberculosis in the log phase of growth. J Infect Dis (2006) 3.04
Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+alpha2beta1+ cell population is enriched in tumor-initiating cells. Cancer Res (2007) 3.00
Herpes simplex virus type 2 infection increases HIV incidence: a prospective study in rural Tanzania. AIDS (2002) 2.93
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther (2009) 2.92
FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J Cell Biol (2002) 2.86
Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. Mol Cell Biol (2002) 2.84
Viral gastroenteritis outbreaks in Europe, 1995-2000. Emerg Infect Dis (2003) 2.79
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice. Mol Ther (2011) 2.75
The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. Cell Stem Cell (2012) 2.69
The promise of microRNA replacement therapy. Cancer Res (2010) 2.68
Sufficiently important difference: expanding the framework of clinical significance. Med Decis Making (2005) 2.65
Functional evidence that the self-renewal gene NANOG regulates human tumor development. Stem Cells (2009) 2.59
Hunting for consensus: reconciling bushmeat harvest, conservation, and development policy in West and Central Africa. Conserv Biol (2007) 2.50
Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization. Blood (2009) 2.49
Validity of the alcohol use disorders identification test in college students. Alcohol Clin Exp Res (2004) 2.30
Longitudinal analysis of CD8+ T cells specific for structural and nonstructural hepatitis B virus proteins in patients with chronic hepatitis B: implications for immunotherapy. J Virol (2004) 2.28
Molecular epidemiology of human enterovirus 71 in the United Kingdom from 1998 to 2006. J Clin Microbiol (2008) 2.24
International collaborative study to compare reverse transcriptase PCR assays for detection and genotyping of noroviruses. J Clin Microbiol (2003) 2.23
Diagnostic reverse-transcription polymerase chain reaction kit for filoviruses based on the strain collections of all European biosafety level 4 laboratories. J Infect Dis (2007) 2.22
PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells. Cancer Res (2008) 2.16
A randomized, controlled trial of an aerosolized vaccine against measles. N Engl J Med (2015) 2.16
Evidence of a large, international network of HCV transmission in HIV-positive men who have sex with men. Gastroenterology (2009) 2.10
Diagnosing norovirus-associated infectious intestinal disease using viral load. BMC Infect Dis (2009) 2.09
Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity. Inhal Toxicol (2007) 2.06
Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity. Immunity (2013) 2.05
The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors. J Biol Chem (2009) 2.05
Global distribution of measles genotypes and measles molecular epidemiology. J Infect Dis (2011) 2.03
Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations. Antimicrob Agents Chemother (2007) 2.02
The pulmonary toxicology of ultrafine particles. J Aerosol Med (2002) 2.02
Temporal analysis of early immune responses in patients with acute hepatitis B virus infection. Gastroenterology (2009) 1.88
Mumps outbreaks across England and Wales in 2004: observational study. BMJ (2005) 1.87
Community incidence of norovirus-associated infectious intestinal disease in England: improved estimates using viral load for norovirus diagnosis. Am J Epidemiol (2010) 1.86
MicroRNA regulation of cancer stem cells. Cancer Res (2011) 1.84
Genome-scale microRNA and small interfering RNA screens identify small RNA modulators of TRAIL-induced apoptosis pathway. Cancer Res (2007) 1.83
Personalized exposure assessment: promising approaches for human environmental health research. Environ Health Perspect (2005) 1.83
Vaccine effectiveness estimates, 2004-2005 mumps outbreak, England. Emerg Infect Dis (2007) 1.79
Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor. Immunity (2013) 1.75
Early identification of common-source foodborne virus outbreaks in Europe. Emerg Infect Dis (2003) 1.75
Dendrodendritic inhibition and simulated odor responses in a detailed olfactory bulb network model. J Neurophysiol (2003) 1.72
Human papillomavirus cofactors by disease progression and human papillomavirus types in the study to understand cervical cancer early endpoints and determinants. Cancer Epidemiol Biomarkers Prev (2009) 1.70
A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine. Crit Care Med (2012) 1.69
Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection. J Exp Med (2002) 1.66
Phenoxodiol--an isoflavone analog--induces apoptosis in chemoresistant ovarian cancer cells. Oncogene (2003) 1.65
Improving the care of patients with regard to chemotherapy-induced nausea and emesis: the effect of feedback to clinicians on adherence to antiemetic prescribing guidelines. J Clin Oncol (2003) 1.64
Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy. Nat Cell Biol (2012) 1.63
FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism. Mol Cell Biol (2004) 1.63
Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy. Blood (2012) 1.61
Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome. Cell (2006) 1.61
MAPK signaling pathways in the regulation of hematopoiesis. J Leukoc Biol (2009) 1.60
Diagnosing rotavirus A associated IID: Using ELISA to identify a cut-off for real time RT-PCR. J Clin Virol (2009) 1.59
Early mitochondrial activation and cytochrome c up-regulation during apoptosis. J Biol Chem (2002) 1.57
Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3. J Biol Chem (2007) 1.57
Apoptosis in Parkinson's disease: signals for neuronal degradation. Ann Neurol (2003) 1.55
Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7. Cancer Res (2012) 1.55
The role of the PI3K-PKB signaling module in regulation of hematopoiesis. Cell Cycle (2009) 1.55
HMG-CoA reductase inhibition induces IL-1beta release through Rac1/PI3K/PKB-dependent caspase-1 activation. Blood (2008) 1.54
FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J Cell Biol (2004) 1.51
Oxymetazoline adds to the effectiveness of fluticasone furoate in the treatment of perennial allergic rhinitis. J Allergy Clin Immunol (2011) 1.49
The extending network of FOXO transcriptional target genes. Antioxid Redox Signal (2010) 1.49
United States feasibility study of transcatheter insertion of a stented aortic valve by the left ventricular apex. Ann Thorac Surg (2008) 1.47
Pharmacodynamics of β-lactamase inhibition by NXL104 in combination with ceftaroline: examining organisms with multiple types of β-lactamases. Antimicrob Agents Chemother (2011) 1.46
Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration. Oncogene (2003) 1.46
Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death. Mol Cell Biol (2004) 1.46
Learning to work together: developing academic and community research partnerships. WMJ (2004) 1.45
High-throughput RNAi screening in vitro: from cell lines to primary cells. RNA (2005) 1.45
Randomized trial of surgical cutdown versus percutaneous access in transfemoral TAVR. Catheter Cardiovasc Interv (2013) 1.45
Toric Implantable Collamer Lens for moderate to high myopic astigmatism. Ophthalmology (2007) 1.45
FOXO transcription factors as regulators of immune homeostasis: molecules to die for? J Immunol (2003) 1.44
Indigenous hepatitis E virus infection in England: more common than it seems. J Clin Virol (2009) 1.44
Serum microRNA biomarkers for detection of non-small cell lung cancer. PLoS One (2012) 1.43
The elimination of indigenous measles transmission in England and Wales. J Infect Dis (2003) 1.42
Incidence and risk factors of paediatric rotavirus diarrhoea in northern Ghana. Trop Med Int Health (2003) 1.42
Survey of select practice behaviors by primary care physicians on the use of opioids for chronic pain. Curr Med Res Opin (2006) 1.41
Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation. Mol Cancer Ther (2003) 1.41
Characterization of G10P[11] rotaviruses causing acute gastroenteritis in neonates and infants in Vellore, India. J Clin Microbiol (2004) 1.41
FOXO3a induces differentiation of Bcr-Abl-transformed cells through transcriptional down-regulation of Id1. J Biol Chem (2006) 1.40
Respiratory syncytial virus inhibits granulocyte apoptosis through a phosphatidylinositol 3-kinase and NF-kappaB-dependent mechanism. J Immunol (2006) 1.40
Reliability of risk algorithms in predicting early and late operative outcomes in high-risk patients undergoing aortic valve replacement. J Thorac Cardiovasc Surg (2007) 1.40
Tracheary element differentiation. Annu Rev Plant Biol (2007) 1.39
Phosphatidylinositol 4-kinasebeta is critical for functional association of rab11 with the Golgi complex. Mol Biol Cell (2004) 1.39
H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa. Genome Res (2015) 1.39