Published in Mol Psychiatry on July 01, 2005
Alterations in somatostatin mRNA expression in the dorsolateral prefrontal cortex of subjects with schizophrenia or schizoaffective disorder. Cereb Cortex (2008) 1.61
Markers of inflammation and stress distinguish subsets of individuals with schizophrenia and bipolar disorder. Transl Psychiatry (2014) 1.59
Decreased BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders. J Psychiatry Neurosci (2011) 1.57
Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection. Pharmacol Rev (2008) 1.46
Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction. Proc Natl Acad Sci U S A (2013) 1.31
Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia. Neurosci Biobehav Rev (2010) 1.24
Cannabis and cognitive dysfunction: parallels with endophenotypes of schizophrenia? J Psychiatry Neurosci (2007) 1.18
Epigenetic mechanisms in schizophrenia. Biochim Biophys Acta (2009) 1.17
Decreased neurotrophic response to birth hypoxia in the etiology of schizophrenia. Biol Psychiatry (2008) 1.10
Brain derived neurotropic factor in first-episode psychosis. Schizophr Res (2007) 1.07
Glutamatergic dysfunction in schizophrenia: from basic neuroscience to clinical psychopharmacology. Eur Neuropsychopharmacol (2008) 1.06
Cell and receptor type-specific alterations in markers of GABA neurotransmission in the prefrontal cortex of subjects with schizophrenia. Neurotox Res (2008) 1.03
Decreased BDNF in patients with antipsychotic naïve first episode schizophrenia. Schizophr Res (2010) 1.02
Increases in two truncated TrkB isoforms in the prefrontal cortex of people with schizophrenia. Schizophr Bull (2011) 0.99
Decreased BDNF and TrkB mRNA expression in multiple cortical areas of patients with schizophrenia and mood disorders. Transl Psychiatry (2014) 0.98
Persistent neural activity in the prefrontal cortex: a mechanism by which BDNF regulates working memory? Prog Brain Res (2008) 0.97
BDNF-TrkB signaling and neuroprotection in schizophrenia. Asian J Psychiatr (2012) 0.94
New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brain-related diseases. World J Biol Chem (2014) 0.93
Cysteamine treatment ameliorates alterations in GAD67 expression and spatial memory in heterozygous reeler mice. Int J Neuropsychopharmacol (2011) 0.91
A selective role for ARMS/Kidins220 scaffold protein in spatial memory and trophic support of entorhinal and frontal cortical neurons. Exp Neurol (2011) 0.91
Prenatal stress differentially alters brain-derived neurotrophic factor expression and signaling across rat strains. Neuroscience (2011) 0.90
Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia. Front Behav Neurosci (2013) 0.89
Cysteamine attenuates the decreases in TrkB protein levels and the anxiety/depression-like behaviors in mice induced by corticosterone treatment. PLoS One (2011) 0.89
Novel animal models for studying complex brain disorders: BAC-driven miRNA-mediated in vivo silencing of gene expression. Mol Psychiatry (2010) 0.87
The interaction of BDNF and NTRK2 gene increases the susceptibility of paranoid schizophrenia. PLoS One (2013) 0.85
Brain-derived neurotrophic factor Val⁶⁶Met polymorphism affects resting regional cerebral blood flow and functional connectivity differentially in women versus men. J Neurosci (2012) 0.84
Schizophrenia and vitamin D related genes could have been subject to latitude-driven adaptation. BMC Evol Biol (2010) 0.84
Cholinergic circuits and signaling in the pathophysiology of schizophrenia. Int Rev Neurobiol (2007) 0.82
Decreased expression of Sprouty2 in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder: a correlation with BDNF expression. PLoS One (2008) 0.82
Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid. Acta Neuropathol Commun (2015) 0.82
Cortical Gene Expression After a Conditional Knockout of 67 kDa Glutamic Acid Decarboxylase in Parvalbumin Neurons. Schizophr Bull (2016) 0.81
TrkB interacts with ErbB4 and regulates NRG1-induced NR2B phosphorylation in cortical neurons before synaptogenesis. Cell Commun Signal (2014) 0.80
Neurotrophin receptors expression in mesial temporal lobe epilepsy with and without psychiatric comorbidities and their relation with seizure type and surgical outcome. Acta Neuropathol Commun (2014) 0.80
Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice. Cell Mol Life Sci (2015) 0.80
Vascular endothelial growth factor and brain-derived neurotrophic factor in quetiapine treated first-episode psychosis. Schizophr Res Treatment (2014) 0.79
Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia. J Psychiatry Neurosci (2014) 0.79
Synapsin III: role in neuronal plasticity and disease. Semin Cell Dev Biol (2011) 0.79
Modulation of schizophrenia-related genes in the forebrain of adolescent and adult rats exposed to maternal immune activation. Schizophr Res (2015) 0.78
Peripheral BDNF: a candidate biomarker of healthy neural activity during learning is disrupted in schizophrenia. Psychol Med (2014) 0.76
Consistently altered expression of gene sets in postmortem brains of individuals with major psychiatric disorders. Transl Psychiatry (2016) 0.76
Neurotrophin signalling: novel insights into mechanisms and pathophysiology. Clin Sci (Lond) (2017) 0.76
Analyzing the influence of BDNF heterozygosity on spatial memory response to 17β-estradiol. Transl Psychiatry (2015) 0.75
Nicotine exposure during adolescence: cognitive performance and brain gene expression in adult heterozygous reeler mice. Psychopharmacology (Berl) (2013) 0.75
Integral Characterization of Defective BDNF/TrkB Signalling in Neurological and Psychiatric Disorders Leads the Way to New Therapies. Int J Mol Sci (2017) 0.75
Rethinking the Epigenetic Framework to Unravel the Molecular Pathology of Schizophrenia. Int J Mol Sci (2017) 0.75
BDNF and NGF Signalling in Early Phases of Psychosis: Relationship With Inflammation and Response to Antipsychotics After 1 Year. Schizophr Bull (2015) 0.75
In SilicoModel-driven Assessment of the Effects of Brain-derived Neurotrophic Factor Deficiency on Glutamate and Gamma-Aminobutyric Acid: Implications for Understanding Schizophrenia Pathophysiology. Clin Psychopharmacol Neurosci (2017) 0.75
The Efficacy of Non-Pharmacological Interventions on Brain-Derived Neurotrophic Factor in Schizophrenia: A Systematic Review and Meta-Analysis. Int J Mol Sci (2016) 0.75
The effect of deficient muscarinic signaling on commonly reported biochemical effects in schizophrenia and convergence with genetic susceptibility loci in explaining symptom dimensions of psychosis. Front Pharmacol (2014) 0.75
Glucocorticoid regulates parkin expression in mouse frontal cortex: implications in schizophrenia. Curr Neuropharmacol (2014) 0.75
Modified Mediterranean Diet for Enrichment of Short Chain Fatty Acids: Potential Adjunctive Therapeutic to Target Immune and Metabolic Dysfunction in Schizophrenia? Front Neurosci (2017) 0.75
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci U S A (2001) 9.42
Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry (2005) 9.23
Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry (1987) 8.81
Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Arch Gen Psychiatry (1986) 4.34
Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited. Cereb Cortex (2000) 3.37
Physiological characteristics of capacity constraints in working memory as revealed by functional MRI. Cereb Cortex (1999) 3.31
Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia. N Engl J Med (1990) 3.10
Neuropsychological assessment of monozygotic twins discordant for schizophrenia. Arch Gen Psychiatry (1990) 3.07
Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method. Proc Natl Acad Sci U S A (1997) 3.00
Evidence for abnormal cortical functional connectivity during working memory in schizophrenia. Am J Psychiatry (2001) 2.80
Cognitive impairments in patients with schizophrenia displaying preserved and compromised intellect. Arch Gen Psychiatry (2000) 2.62
Noise reduction in 3D perfusion imaging by attenuating the static signal in arterial spin tagging (ASSIST). Magn Reson Med (2000) 2.58
Neurophysiological correlates of age-related changes in human motor function. Neurology (2002) 2.52
Auditory working memory and Wisconsin Card Sorting Test performance in schizophrenia. Arch Gen Psychiatry (1997) 2.48
Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia. Mol Psychiatry (2002) 2.43
Disseminated necrotizing leukoencephalopathy: a complication of treated central nervous system leukemia and lymphoma. Cancer (1975) 2.32
A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity. Biol Psychiatry (2000) 2.32
Genotype influences in vivo dopamine transporter availability in human striatum. Neuropsychopharmacology (2000) 2.28
Further evidence for dementia of the prefrontal type in schizophrenia? A controlled study of teaching the Wisconsin Card Sorting Test. Arch Gen Psychiatry (1987) 2.24
Impact of complex genetic variation in COMT on human brain function. Mol Psychiatry (2006) 2.22
H(2)(15)O PET validation of steady-state arterial spin tagging cerebral blood flow measurements in humans. Magn Reson Med (2000) 2.20
Modulation of cognition-specific cortical activity by gonadal steroids: a positron-emission tomography study in women. Proc Natl Acad Sci U S A (1997) 2.19
Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia. Mol Psychiatry (2003) 2.18
Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression. Mol Psychiatry (2007) 2.12
Relative risk for cognitive impairments in siblings of patients with schizophrenia. Biol Psychiatry (2001) 2.08
Schizophrenia and temporal lobe epilepsy. A neuropsychological analysis. Arch Gen Psychiatry (1994) 2.07
Treatment of tardive dyskinesia with vitamin E. Am J Psychiatry (1992) 2.07
Relative risk of attention deficits in siblings of patients with schizophrenia. Am J Psychiatry (2000) 2.07
Genetic contributions to regional variability in human brain structure: methods and preliminary results. Neuroimage (2002) 2.01
Postpubertal emergence of hyperresponsiveness to stress and to amphetamine after neonatal excitotoxic hippocampal damage: a potential animal model of schizophrenia. Neuropsychopharmacology (1993) 1.99
Lateral cerebral ventricular enlargement in chronic schizophrenia. Arch Gen Psychiatry (1979) 1.94
Binding of thyroglobulin and thyroglobulin-antithyroglobulin immune complex to extraocular muscle membrane. Endocrinology (1974) 1.92
Genetic variability of human brain size and cortical gyral patterns. Brain (1997) 1.92
Psychiatric disturbances in metachromatic leukodystrophy. Insights into the neurobiology of psychosis. Arch Neurol (1992) 1.91
Cognitive substrates of thought disorder, I: the semantic system. Am J Psychiatry (1998) 1.90
Electron microscopic observations in infantile neuroaxonal dystrophy. Report of a cortical biopsy and review of the recent literature. Arch Neurol (1969) 1.90
To model a psychiatric disorder in animals: schizophrenia as a reality test. Neuropsychopharmacology (2000) 1.89
Serotonergic dysfunction, negative mood states, and response to alcohol. Alcohol Clin Exp Res (2001) 1.85
Contrasts between patients with affective disorders and patients with schizophrenia on a neuropsychological test battery. Am J Psychiatry (1993) 1.78
The effect of clozapine on cognition and psychiatric symptoms in patients with schizophrenia. Br J Psychiatry (1993) 1.75
Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function. Neuroscience (2003) 1.74
A light- and electron-microscopic study of a temporal-lobe ganglioglioma. J Neurol Sci (1972) 1.73
Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Arch Gen Psychiatry (1995) 1.71
Genetic variants in AVPR1A linked to autism predict amygdala activation and personality traits in healthy humans. Mol Psychiatry (2008) 1.70
Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression. Mol Psychiatry (2008) 1.66
Physiological activation of a cortical network during performance of the Wisconsin Card Sorting Test: a positron emission tomography study. Neuropsychologia (1995) 1.65
COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C]NNC112 and PET. Mol Psychiatry (2008) 1.63
Effects of dextroamphetamine on cognitive performance and cortical activation. Neuroimage (2000) 1.63
Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia. Mol Psychiatry (2004) 1.62
Correction for vascular artifacts in cerebral blood flow values measured by using arterial spin tagging techniques. Magn Reson Med (1997) 1.61
The relationship between dorsolateral prefrontal N-acetylaspartate measures and striatal dopamine activity in schizophrenia. Biol Psychiatry (1999) 1.60
Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. IV. Further evidence for regional and behavioral specificity. Arch Gen Psychiatry (1988) 1.58
Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology (1993) 1.58
GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss. Mol Psychiatry (2005) 1.56
Functional magnetic resonance imaging brain mapping in psychiatry: methodological issues illustrated in a study of working memory in schizophrenia. Neuropsychopharmacology (1998) 1.54
The neurodevelopmental hypothesis of schizophrenia: following a trail of evidence from cradle to grave. Dev Psychopathol (2000) 1.54
Genetic variation in MAOA modulates ventromedial prefrontal circuitry mediating individual differences in human personality. Mol Psychiatry (2007) 1.54
Selective abnormalities of prefrontal serotonergic receptors in schizophrenia. A postmortem study. Arch Gen Psychiatry (1993) 1.52
Serious obstetric complications interact with hypoxia-regulated/vascular-expression genes to influence schizophrenia risk. Mol Psychiatry (2008) 1.51
BDNF and trkB mRNA expression in the hippocampus and temporal cortex during the human lifespan. Gene Expr Patterns (2006) 1.48
Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine. Psychopharmacology (Berl) (1995) 1.48
Is the mechanism of prefrontal hypofunction in depression the same as in schizophrenia? Regional cerebral blood flow during cognitive activation. Br J Psychiatry (1993) 1.47
Choline acetyltransferase in schizophrenia. Am J Psychiatry (1993) 1.47
Catechol-o-methyltransferase enzyme activity and protein expression in human prefrontal cortex across the postnatal lifespan. Cereb Cortex (2006) 1.46
A comparison of rCBF patterns during letter and semantic fluency. Neuropsychology (2000) 1.45
Monoclonal antibodies to study the brain in schizophrenia. Brain Res (1989) 1.45
Searching for a consensus five-factor model of the Positive and Negative Syndrome Scale for schizophrenia. Schizophr Res (2012) 1.44
Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. II. Role of neuroleptic treatment, attention, and mental effort. Arch Gen Psychiatry (1986) 1.42
MRI asymmetries of Broca's area: the pars triangularis and pars opercularis. Brain Lang (1998) 1.41
A quantitative analysis of smooth pursuit eye tracking in monozygotic twins discordant for schizophrenia. Arch Gen Psychiatry (1997) 1.41
Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain. Neuroscience (2004) 1.40
Biology of the human malignant lymphomas. III. Intracranial heterotransplantation in the nude, athymic mouse. Cancer (1976) 1.40
Localization of epidermal growth factor receptors and putative neuroblasts in human subependymal zone. J Comp Neurol (2000) 1.40
Basal ganglia iron in tardive dyskinesia: an MRI study. Biol Psychiatry (1994) 1.39
Hemispheric control of motor function: a whole brain echo planar fMRI study. Psychiatry Res (1998) 1.38
Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia. Mol Psychiatry (2007) 1.38
Characteristics of the rat C-6 glioma maintained in organ culture systems. Production of glial fibrillary acidic protein in the absence of gliofibrillogenesis. Brain Res (1974) 1.37
Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice. Mol Psychiatry (2007) 1.32