Published in World J Biol Chem on November 26, 2014
Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons. Acta Neuropathol Commun (2015) 1.45
Host microbiota modulates development of social preference in mice. Microb Ecol Health Dis (2015) 0.85
Effects of cigarette smoking and alcohol use on neurocognition and BDNF levels in a Chinese population. Psychopharmacology (Berl) (2015) 0.80
Brain-derived neurotrophic factor genetic polymorphism (rs6265) is protective against chemotherapy-associated cognitive impairment in patients with early-stage breast cancer. Neuro Oncol (2015) 0.79
Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models. Front Psychiatry (2015) 0.79
Stimulation of synthesis and release of brain-derived neurotropic factor from intestinal smooth muscle cells by substance P and pituitary adenylate cyclase-activating peptide. Neurogastroenterol Motil (2015) 0.78
Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal Neurons. Neural Plast (2016) 0.77
Current Perspective of Stem Cell Therapy in Neurodegenerative and Metabolic Diseases. Mol Neurobiol (2016) 0.76
Protective effect of chronic caffeine intake on gene expression of brain derived neurotrophic factor signaling and the immunoreactivity of glial fibrillary acidic protein and Ki-67 in Alzheimer's disease. Int J Clin Exp Pathol (2015) 0.76
Transcriptional Regulation of Brain-derived Neurotrophic Factor Coding Exon IX: ROLE OF NUCLEAR RESPIRATORY FACTOR 2. J Biol Chem (2016) 0.76
Assessment of glomerular filtration rate based on alterations of serum brain-derived neurotrophic factor in type 2 diabetic subjects treated with amlodipine/benazepril or valsartan/hydrochlorothiazide. Dis Markers (2015) 0.75
Mechanisms and regulation of neurotrophin synthesis and secretion. Neurosciences (Riyadh) (2016) 0.75
TOX and ADIPOQ Gene Polymorphisms Are Associated with Antipsychotic-Induced Weight Gain in Han Chinese. Sci Rep (2017) 0.75
The human BDNF gene: peripheral gene expression and protein levels as biomarkers for psychiatric disorders. Transl Psychiatry (2016) 0.75
Serum brain-derived neurotrophic factor and risk of atrial fibrillation. Am Heart J (2016) 0.75
Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders. Front Aging Neurosci (2016) 0.75
Effects of Fluid Ingestion on Brain-Derived Neurotrophic Factor and Cognition During Exercise in the Heat. J Hum Kinet (2017) 0.75
Amyloid-β Impairs Vesicular Secretion in Neuronal and Astrocyte Peptidergic Transmission. Front Mol Neurosci (2017) 0.75
Phorbol esters dPPA/dPA promote furin expression involving transcription factor CEBPβ in neuronal cells. Oncotarget (2017) 0.75
Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (1991) 49.03
LTP and LTD: an embarrassment of riches. Neuron (2004) 15.48
Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J Physiol (1973) 14.99
Alzheimer's disease is a synaptic failure. Science (2002) 13.82
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell (2003) 12.50
MeCP2, a key contributor to neurological disease, activates and represses transcription. Science (2008) 10.11
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J Neurosci (2000) 9.85
Stress and the brain: from adaptation to disease. Nat Rev Neurosci (2005) 9.48
A neurotrophic model for stress-related mood disorders. Biol Psychiatry (2006) 8.97
Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem (2003) 8.83
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science (2003) 8.48
Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry (1991) 8.10
Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat Rev Neurosci (2003) 7.44
Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch Gen Psychiatry (1995) 7.19
Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch Gen Psychiatry (2000) 6.91
Regulation of cell survival by secreted proneurotrophins. Science (2001) 6.32
Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science (2006) 5.89
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell (2004) 5.67
BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex. Cell (1999) 5.63
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science (2009) 5.24
Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science (1995) 5.19
Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron (1996) 5.19
Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci (1995) 5.10
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat Genet (2003) 4.76
Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science (2004) 4.74
The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression. Neuron (2006) 4.74
The yin and yang of neurotrophin action. Nat Rev Neurosci (2005) 4.45
GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity. Cell (2005) 4.42
Essential role for TrkB receptors in hippocampus-mediated learning. Neuron (1999) 4.20
A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus. Proc Natl Acad Sci U S A (2001) 4.16
Mouse and rat BDNF gene structure and expression revisited. J Neurosci Res (2007) 4.13
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nat Med (2009) 4.11
Activity-dependent regulation of inhibitory synapse development by Npas4. Nature (2008) 4.10
Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biol Psychiatry (2008) 4.06
Anterograde transport of brain-derived neurotrophic factor and its role in the brain. Nature (1997) 4.01
A NERVE GROWTH-STIMULATING FACTOR ISOLATED FROM SARCOM AS 37 AND 180. Proc Natl Acad Sci U S A (1954) 4.00
Purification of a new neurotrophic factor from mammalian brain. EMBO J (1982) 3.68
Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection. Neuron (2008) 3.65
Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons. Cell (2008) 3.63
Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. J Neurosci (1995) 3.56
Neurotrophin regulation of neural circuit development and function. Nat Rev Neurosci (2013) 3.53
The HPA axis in major depression: classical theories and new developments. Trends Neurosci (2008) 3.47
Multiple promoters direct tissue-specific expression of the rat BDNF gene. Neuron (1993) 3.44
Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport. J Neurosci (1997) 3.41
A biological function for the neuronal activity-dependent component of Bdnf transcription in the development of cortical inhibition. Neuron (2008) 3.40
Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Res (2002) 3.31
Activation of p75NTR by proBDNF facilitates hippocampal long-term depression. Nat Neurosci (2005) 3.17
TrkB signalling pathways in LTP and learning. Nat Rev Neurosci (2009) 3.12
Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry (2003) 3.12
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proc Natl Acad Sci U S A (2009) 2.96
BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory? Neurobiol Learn Mem (2007) 2.96
Brain-derived neurotrophic factor in neurodegenerative diseases. Nat Rev Neurol (2009) 2.93
Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry (2001) 2.92
cAMP-induced switching in turning direction of nerve growth cones. Nature (1997) 2.90
Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics (2007) 2.89
Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories. Mol Psychiatry (2007) 2.84
Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry (2003) 2.82
Differential loss of striatal projection neurons in Huntington disease. Proc Natl Acad Sci U S A (1988) 2.78
Polarized secretory trafficking directs cargo for asymmetric dendrite growth and morphogenesis. Neuron (2005) 2.77
Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO J (1990) 2.77
Antidepressant-like effect of brain-derived neurotrophic factor (BDNF). Pharmacol Biochem Behav (1997) 2.67
Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. J Neurosci (2003) 2.66
Potential therapeutic uses of BDNF in neurological and psychiatric disorders. Nat Rev Drug Discov (2011) 2.65
A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF. Neuron (2002) 2.65
Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity. Mol Psychiatry (2008) 2.65
Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons. Nat Neurosci (2005) 2.59
Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors. Proc Natl Acad Sci U S A (1995) 2.58
Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia. Biol Psychiatry (2007) 2.55
Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J (1990) 2.54
BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses. J Neurosci (2001) 2.51
BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease. Neuron (1991) 2.46
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. J Neurosci (2005) 2.44
Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses. EMBO J (2001) 2.38
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF. Nat Neurosci (2008) 2.38
Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine. Brain Res (2005) 2.34
New insights into brain BDNF function in normal aging and Alzheimer disease. Brain Res Rev (2008) 2.28
Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice. J Neurosci (1999) 2.26
Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family. Neuron (1990) 2.22
Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex. Proc Natl Acad Sci U S A (1992) 2.19
BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones. Neuroreport (1994) 2.19
Inhibition of GABAA synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus. J Neurosci (1997) 2.18
Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia. Mol Psychiatry (2003) 2.18
Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. J Neurosci (2005) 2.18
Role of brain-derived neurotrophic factor in Huntington's disease. Prog Neurobiol (2007) 2.17
Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor. J Neurosci (2004) 2.16
Dual modes of endoplasmic reticulum-to-Golgi transport in dendrites revealed by live-cell imaging. J Neurosci (2003) 2.15
Activation of a TRPC3-dependent cation current through the neurotrophin BDNF. Neuron (1999) 2.15
Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. Mol Psychiatry (2004) 2.11
BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF. Neuron (1991) 2.10
Effects of brain-derived neurotrophic factor on optic axon branching and remodelling in vivo. Nature (1995) 2.08
Brain-derived neurotrophic factor is reduced in Alzheimer's disease. Brain Res Mol Brain Res (1997) 2.08
Mechanism of TrkB-mediated hippocampal long-term potentiation. Neuron (2002) 2.03
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons. EMBO J (2008) 2.03
BDNF in schizophrenia, depression and corresponding animal models. Mol Psychiatry (2005) 2.00
Neurotrophic factors and structural plasticity in addiction. Neuropharmacology (2008) 1.99
Pro-region of neurotrophins: role in synaptic modulation. Neuron (2003) 1.98
Low plasma BDNF is associated with suicidal behavior in major depression. Prog Neuropsychopharmacol Biol Psychiatry (2006) 1.98
Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Brain Res Mol Brain Res (2005) 1.96
Neurotrophins induce formation of functional excitatory and inhibitory synapses between cultured hippocampal neurons. J Neurosci (1998) 1.95
Visualizing synapse formation in arborizing optic axons in vivo: dynamics and modulation by BDNF. Nat Neurosci (2001) 1.93