Published in Cells Tissues Organs on January 01, 2005
Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice. Hepatology (2010) 3.10
The lens capsule. Exp Eye Res (2008) 1.32
Ligand-independent regulation of transforming growth factor beta1 expression and cell cycle progression by the aryl hydrocarbon receptor. Mol Cell Biol (2007) 1.30
Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol (2007) 1.17
Pax6 regulates gene expression in the vertebrate lens through miR-204. PLoS Genet (2013) 1.11
The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial-mesenchymal transition of lens epithelial cells. Cell Death Dis (2013) 1.09
Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Dev Dyn (2008) 1.08
Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens. Dev Biol (2010) 1.08
Prevention of posterior capsular opacification through aldose reductase inhibition. Invest Ophthalmol Vis Sci (2008) 1.07
The anaphase-promoting complex coordinates initiation of lens differentiation. Mol Biol Cell (2007) 1.03
Lens-specific expression of TGF-beta induces anterior subcapsular cataract formation in the absence of Smad3. Invest Ophthalmol Vis Sci (2006) 1.03
Focal adhesion kinase (FAK) expression and activation during lens development. Mol Vis (2007) 1.00
The lens as a model for fibrotic disease. Philos Trans R Soc Lond B Biol Sci (2011) 0.97
Wnt3a promotes epithelial-mesenchymal transition, migration, and proliferation of lens epithelial cells. Mol Vis (2012) 0.95
The Roles of Mitogen-Activated Protein Kinase Pathways in TGF-β-Induced Epithelial-Mesenchymal Transition. J Signal Transduct (2012) 0.94
A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol (2009) 0.94
Oxidative damage and TGF-β differentially induce lung epithelial cell sonic hedgehog and tenascin-C expression: implications for the regulation of lung remodelling in idiopathic interstitial lung disease. Int J Exp Pathol (2010) 0.94
Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract. Mol Vis (2007) 0.93
Osmotic stress, not aldose reductase activity, directly induces growth factors and MAPK signaling changes during sugar cataract formation. Exp Eye Res (2012) 0.92
Retinal phototoxicity in a novel murine model of intraocular lens implantation. Mol Vis (2009) 0.92
Lens intermediate filaments. Exp Eye Res (2008) 0.91
Post-operative capsular opacification: a review. Int J Biomed Sci (2007) 0.91
Subepithelial corneal fibrosis partially due to epithelial-mesenchymal transition of ocular surface epithelium. Mol Vis (2010) 0.91
What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease. Exp Eye Res (2013) 0.90
X-ray induced cataract is preceded by LEC loss, and coincident with accumulation of cortical DNA, and ROS; similarities with age-related cataracts. Mol Vis (2010) 0.90
Matrix Metalloproteinases as Mediators of Primary and Secondary Cataracts. Expert Rev Ophthalmol (2007) 0.89
The roles of αV integrins in lens EMT and posterior capsular opacification. J Cell Mol Med (2014) 0.89
Loss of NF-kappaB control and repression of Prdx6 gene transcription by reactive oxygen species-driven SMAD3-mediated transforming growth factor beta signaling. J Biol Chem (2009) 0.86
mTOR regulates TGF-β₂-induced epithelial-mesenchymal transition in cultured human lens epithelial cells. Graefes Arch Clin Exp Ophthalmol (2013) 0.86
Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse. Dev Biol (2013) 0.86
Expression of integrin-linked kinase in the murine lens is consistent with its role in epithelial-mesenchymal transition of lens epithelial cells in vitro. Mol Vis (2007) 0.84
Nuclear translocation of myocardin-related transcription factor-A during transforming growth factor beta-induced epithelial to mesenchymal transition of lens epithelial cells. Mol Vis (2013) 0.84
Early differential expression of oncostatin M in obstructive nephropathy. J Interferon Cytokine Res (2010) 0.84
RNA Interference Targeting Snail Inhibits the Transforming Growth Factor β 2-Induced Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells. J Ophthalmol (2013) 0.83
Suppression of injury-induced epithelial-mesenchymal transition in a mouse lens epithelium lacking tenascin-C. Mol Vis (2010) 0.83
Prevention of posterior capsular opacification through cyclooxygenase-2 inhibition. Mol Vis (2007) 0.83
TGF-β2 induces epithelial-mesenchymal transition in cultured human lens epithelial cells through activation of the PI3K/Akt/mTOR signaling pathway. Mol Med Rep (2015) 0.83
The lens in focus: a comparison of lens development in Drosophila and vertebrates. Mol Genet Genomics (2011) 0.82
Quantitative analysis of injury-induced anterior subcapsular cataract in the mouse: a model of lens epithelial cells proliferation and epithelial-mesenchymal transition. Sci Rep (2015) 0.82
Induction of corneal myofibroblasts by lens-derived transforming growth factor beta1 (TGFbeta1): a transgenic mouse model. Brain Res Bull (2009) 0.82
ERalpha increases expression and interacts with TERT in cataractous canine lens epithelial cells. Mol Vis (2009) 0.82
CD44 expression is developmentally regulated in the mouse lens and increases in the lens epithelium after injury. Differentiation (2009) 0.82
Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. Invest Ophthalmol Vis Sci (2012) 0.81
Phosphatidylinositol synthase is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye. Exp Eye Res (2011) 0.81
Glutathione and catalase suppress TGFbeta-induced cataract-related changes in cultured rat lenses and lens epithelial explants. Mol Vis (2009) 0.81
Aldose Reductase Mediates Transforming Growth Factor β2 (TGF-β2)-Induced Migration and Epithelial-To-Mesenchymal Transition of Lens-Derived Epithelial Cells. Invest Ophthalmol Vis Sci (2015) 0.79
The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model. Mol Vis (2010) 0.79
Myo/Nog cells: targets for preventing the accumulation of skeletal muscle-like cells in the human lens. PLoS One (2014) 0.78
Elevated tropomyosin expression is associated with epithelial-mesenchymal transition of lens epithelial cells. J Cell Mol Med (2012) 0.78
Sustained-release celecoxib from incubated acrylic intraocular lenses suppresses lens epithelial cell growth in an ex vivo model of posterior capsule opacity. J Ocul Pharmacol Ther (2012) 0.78
SiRNA targeting EGFR effectively prevents posterior capsular opacification after cataract surgery. Mol Vis (2011) 0.78
Effect of delivery of MMP inhibitors from PDMS as a model IOL material on PCO markers. Biomaterials (2009) 0.77
Patterns of gene expression in microarrays and expressed sequence tags from normal and cataractous lenses. Hum Genomics (2012) 0.77
Downregulation of transforming growth factor-β type II receptor prohibit epithelial-to-mesenchymal transition in lens epithelium. Mol Vis (2012) 0.77
IGF-1 counteracts TGF-beta-mediated enhancement of fibronectin for in vitro human lens epithelial cells. Yonsei Med J (2007) 0.77
Growth factor restriction impedes progression of wound healing following cataract surgery: identification of VEGF as a putative therapeutic target. Sci Rep (2016) 0.76
The Zeb proteins δEF1 and Sip1 may have distinct functions in lens cells following cataract surgery. Invest Ophthalmol Vis Sci (2014) 0.76
Fibrosis in the lens. Sprouty regulation of TGFβ-signaling prevents lens EMT leading to cataract. Exp Eye Res (2015) 0.76
RhoA/ROCK signaling regulates TGFβ-induced epithelial-mesenchymal transition of lens epithelial cells through MRTF-A. Mol Med (2016) 0.76
Expression of transcription factors Slug in the lens epithelial cells undergoing epithelial-mesenchymal transition induced by connective tissue growth factor. Int J Ophthalmol (2015) 0.76
αB-crystallin is essential for the TGF-β2-mediated epithelial to mesenchymal transition of lens epithelial cells. Biochem J (2016) 0.76
FGF2 antagonizes aberrant TGFβ regulation of tropomyosin: role for posterior capsule opacity. J Cell Mol Med (2016) 0.75
β1-integrin controls cell fate specification in early lens development. Differentiation (2016) 0.75
Echistatin prevents posterior capsule opacification in diabetic rabbit model via integrin linked kinase signaling pathway. Int J Clin Exp Pathol (2015) 0.75
AGE-RAGE interaction in the TGFβ2-mediated epithelial to mesenchymal transition of human lens epithelial cells. Glycoconj J (2016) 0.75
Long noncoding RNA expression profile in HLE B-3 cells during TGF-β2-induced epithelial-mesenchymal transition. BMC Ophthalmol (2017) 0.75
De-ubiquitinating enzyme, USP11, promotes transforming growth factor β-1 signaling through stabilization of transforming growth factor β receptor II. Cell Death Dis (2016) 0.75
Attenuation of human lens epithelial cell spreading, migration and contraction via downregulation of the PI3K/Akt pathway. Graefes Arch Clin Exp Ophthalmol (2013) 0.75
Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract. Mol Biol Cell (2017) 0.75
Bone Morphogenetic Protein-7 Suppresses TGFβ2-Induced Epithelial-Mesenchymal Transition in the Lens: Implications for Cataract Prevention. Invest Ophthalmol Vis Sci (2017) 0.75
β1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci (2017) 0.75
MicroRNA-26a and -26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1/Notch signaling pathway. Cell Death Differ (2017) 0.75
ERK1/2 signaling is required for the initiation but not progression of TGFβ-induced lens epithelial to mesenchymal transition (EMT). Exp Eye Res (2017) 0.75
Roles of TGFβ and FGF signals during growth and differentiation of mouse lens epithelial cell in vitro. Sci Rep (2017) 0.75
Growth factor regulation of lens development. Dev Biol (2005) 2.46
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Cataract induction in lenses cultured with transforming growth factor-beta. Invest Ophthalmol Vis Sci (1995) 1.57
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FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling. Development (2001) 1.49
Lens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts. J Clin Invest (1998) 1.40
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TGF-beta 1 induces lens cells to accumulate alpha-smooth muscle actin, a marker for subcapsular cataracts. Curr Eye Res (1994) 1.34
Cell division, cell elongation and the co-ordination of crystallin gene expression during lens morphogenesis in the rat. J Embryol Exp Morphol (1978) 1.33
Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development. Genes Dev (1997) 1.30
Smad translocation and growth suppression in lens epithelial cells by endogenous TGFbeta2 during wound repair. Exp Eye Res (2001) 1.20
Understanding the role of growth factors in embryonic development: insights from the lens. Philos Trans R Soc Lond B Biol Sci (2011) 1.20
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TGFbeta-Smad signalling in postoperative human lens epithelial cells. Br J Ophthalmol (2002) 1.14
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Requirement for TGFbeta receptor signaling during terminal lens fiber differentiation. Development (2001) 1.11
Patterning the optic neuroepithelium by FGF signaling and Ras activation. Development (2001) 1.09
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Neural retinas promote cell division and fibre differentiation in lens epithelial explants. Curr Eye Res (1984) 1.07
A role for Wnt/planar cell polarity signaling during lens fiber cell differentiation? Semin Cell Dev Biol (2006) 1.06
Spatio-temporal distribution of acidic and basic FGF indicates a role for FGF in rat lens morphogenesis. Dev Dyn (1993) 1.05
Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development. Gene Expr Patterns (2004) 1.04
Differential cataractogenic potency of TGF-beta1, -beta2, and -beta3 and their expression in the postnatal rat eye. Invest Ophthalmol Vis Sci (1998) 1.04
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Inhibition of transforming growth factor-beta-induced cataractous changes in lens explants by ocular media and alpha 2-macroglobulin. Invest Ophthalmol Vis Sci (1996) 1.02
Estrogen protects lenses against cataract induced by transforming growth factor-beta (TGFbeta). J Exp Med (1997) 1.00
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Structural analysis of lens epithelial explants induced to differentiate into fibres by fibroblast growth factor (FGF). Exp Eye Res (1989) 1.00
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Spatial and temporal expression of p57(KIP2) during murine lens development. Mech Dev (1999) 0.99
Intravitreal injection of TGFbeta induces cataract in rats. Invest Ophthalmol Vis Sci (1999) 0.97
Induction and maintenance of differentiation of rat lens epithelium by FGF-2, insulin and IGF-1. Exp Eye Res (1998) 0.95
TGFbeta promotes Wnt expression during cataract development. Exp Eye Res (2008) 0.95
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Lithium stabilizes the polarized lens epithelial phenotype and inhibits proliferation, migration, and epithelial mesenchymal transition. J Pathol (2006) 0.92
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Deregulation of lens epithelial cell proliferation and differentiation during the development of TGFbeta-induced anterior subcapsular cataract. Dev Neurosci (2004) 0.91
Differential effects of aqueous and vitreous on fiber differentiation and extracellular matrix accumulation in lens epithelial explants. Invest Ophthalmol Vis Sci (1995) 0.89
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Ubiquitin-dependent pathway is up-regulated in differentiating lens cells. Exp Eye Res (1999) 0.89
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IGF enhancement of FGF-induced fibre differentiation and DNA synthesis in lens explants. Exp Eye Res (1996) 0.88
IGF-1 enhancement of FGF-induced lens fiber differentiation in rats of different ages. Invest Ophthalmol Vis Sci (1993) 0.88
Expression of FGF-1 and FGF-2 mRNA during lens morphogenesis, differentiation and growth. Curr Eye Res (1997) 0.87
Susceptibility to TGFbeta2-induced cataract increases with aging in the rat. Invest Ophthalmol Vis Sci (2000) 0.87
FGF receptor-1 (flg) expression is correlated with fibre differentiation during rat lens morphogenesis and growth. Dev Dyn (1996) 0.86
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Age of rats affects response of lens epithelial explants to fibroblast growth factor. Exp Eye Res (1992) 0.80
Lens tropomodulin: developmental expression during differentiation. Exp Eye Res (1996) 0.80
The effects of insulin and basic fibroblast growth factor on fibre differentiation in rat lens epithelial explants. Growth Factors (1991) 0.80
The age of rats affects the response of lens epithelial explants to fibroblast growth factor. An ultrastructural analysis. Invest Ophthalmol Vis Sci (1992) 0.79
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Peter Bishop Lecture: growth factors in lens development and cataract: key roles for fibroblast growth factor and TGF-beta. Clin Experiment Ophthalmol (2000) 0.78
Age-related changes in fibre differentiation of rat lens epithelial explants exposed to fibroblast growth factor. Exp Eye Res (1990) 0.78
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A lens fibre differentiation factor from calf neural retina. Exp Cell Res (1986) 0.77
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