Published in Exp Eye Res on October 01, 1998
A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle. Genes Dev (2000) 1.65
An essential role for FGF receptor signaling in lens development. Semin Cell Dev Biol (2006) 1.58
Understanding the role of growth factors in embryonic development: insights from the lens. Philos Trans R Soc Lond B Biol Sci (2011) 1.20
Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease. J Clin Invest (2004) 1.16
MAPK/ERK1/2 and PI3-kinase signalling pathways are required for vitreous-induced lens fibre cell differentiation. Exp Eye Res (2008) 1.00
Elevated insulin signaling disrupts the growth and differentiation pattern of the mouse lens. Mol Vis (2007) 0.95
Growth factor signaling in vitreous humor-induced lens fiber differentiation. Invest Ophthalmol Vis Sci (2010) 0.92
Cellular distribution of lens epithelium-derived growth factor (LEDGF) in the rat eye: loss of LEDGF from nuclei of differentiating cells. Histochem Cell Biol (2003) 0.90
IGF-1 Signaling Plays an Important Role in the Formation of Three-Dimensional Laminated Neural Retina and Other Ocular Structures From Human Embryonic Stem Cells. Stem Cells (2015) 0.85
Intrinsic lens forming potential of mouse lens epithelial versus newt iris pigment epithelial cells in three-dimensional culture. Tissue Eng Part C Methods (2013) 0.82
Sequence and functional conservation of the intergenic region between the head-to-head genes encoding the small heat shock proteins alphaB-crystallin and HspB2 in the mammalian lineage. J Mol Evol (2004) 0.82
IGF-1 counteracts TGF-beta-mediated enhancement of fibronectin for in vitro human lens epithelial cells. Yonsei Med J (2007) 0.77
Effects of long-acting somatostatin analogues on redox systems in rat lens in experimental diabetes. Int J Exp Pathol (2014) 0.75
Growth factor regulation of lens development. Dev Biol (2005) 2.46
Human gamma-crystallin genes. A gene family on its way to extinction. J Mol Biol (1990) 2.08
Chimeric cDNA clones: a novel PCR artifact. Nucleic Acids Res (1991) 2.07
Molecular basis of a progressive juvenile-onset hereditary cataract. Proc Natl Acad Sci U S A (2000) 2.04
Induction of cataract-like changes in rat lens epithelial explants by transforming growth factor beta. Invest Ophthalmol Vis Sci (1994) 1.92
Transforming growth factor-beta-induced epithelial-mesenchymal transition in the lens: a model for cataract formation. Cells Tissues Organs (2005) 1.85
Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration. Development (1989) 1.80
Cataract induction in lenses cultured with transforming growth factor-beta. Invest Ophthalmol Vis Sci (1995) 1.57
Cell division, cell elongation and distribution of alpha-, beta- and gamma-crystallins in the rat lens. J Embryol Exp Morphol (1978) 1.53
FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling. Development (2001) 1.49
Activation of the gamma E-crystallin pseudogene in the human hereditary Coppock-like cataract. Hum Mol Genet (1994) 1.47
The evolution of lenticular proteins: the beta- and gamma-crystallin super gene family. Prog Biophys Mol Biol (1988) 1.45
Lens development. Eye (Lond) (1999) 1.38
TGF-beta 1 induces lens cells to accumulate alpha-smooth muscle actin, a marker for subcapsular cataracts. Curr Eye Res (1994) 1.34
Vascular permeability factor expression influences tumor angiogenesis in human melanoma lines xenografted to nude mice. Am J Pathol (1995) 1.33
The stability of human acidic beta-crystallin oligomers and hetero-oligomers. Exp Eye Res (2003) 1.33
Covalent dimerization of vascular permeability factor/vascular endothelial growth factor is essential for its biological activity. Evidence from Cys to Ser mutations. J Biol Chem (1994) 1.33
Cell division, cell elongation and the co-ordination of crystallin gene expression during lens morphogenesis in the rat. J Embryol Exp Morphol (1978) 1.33
A locus for a human hereditary cataract is closely linked to the gamma-crystallin gene family. Proc Natl Acad Sci U S A (1987) 1.31
Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development. Genes Dev (1997) 1.30
Human alphaB-crystallin. Small heat shock protein and molecular chaperone. J Biol Chem (1997) 1.22
Smad translocation and growth suppression in lens epithelial cells by endogenous TGFbeta2 during wound repair. Exp Eye Res (2001) 1.20
Understanding the role of growth factors in embryonic development: insights from the lens. Philos Trans R Soc Lond B Biol Sci (2011) 1.20
Acidic and basic FGF in ocular media and lens: implications for lens polarity and growth patterns. Development (1993) 1.18
Growth factors in the eye. Prog Growth Factor Res (1990) 1.18
Crystallin gene expression during rat lens development. Eur J Biochem (1989) 1.17
TGFbeta-Smad signalling in postoperative human lens epithelial cells. Br J Ophthalmol (2002) 1.14
New cell line: established cell lines of Drosophila hydei. In Vitro (1980) 1.14
Concerted and divergent evolution within the rat gamma-crystallin gene family. J Mol Biol (1986) 1.13
Rapid and high resolution detection of in situ hybridisation to polytene chromosomes using fluorochrome-labeled RNA. Chromosoma (1981) 1.12
Association behaviour of human betaB1-crystallin and its truncated forms. Exp Eye Res (2001) 1.12
Induction of the eye lens. Differentiation (1980) 1.12
Requirement for TGFbeta receptor signaling during terminal lens fiber differentiation. Development (2001) 1.11
Analysis of the tumor vasculature and metastatic behavior of xenografts of human melanoma cell lines transfected with vascular permeability factor. Am J Pathol (1996) 1.09
Cell specialization in the small intestinal epithelium of adult Xenopus laevis: structural aspects. J Anat (1978) 1.08
In situ hybridization of nuclear and cytoplasmic RNA to locus 2-48BC in Drosophila hydei. Chromosoma (1978) 1.08
Neural retinas promote cell division and fibre differentiation in lens epithelial explants. Curr Eye Res (1984) 1.07
A role for Wnt/planar cell polarity signaling during lens fiber cell differentiation? Semin Cell Dev Biol (2006) 1.06
Different evolution rates within the lens-specific beta-crystallin gene family. J Mol Evol (1989) 1.05
Spatio-temporal distribution of acidic and basic FGF indicates a role for FGF in rat lens morphogenesis. Dev Dyn (1993) 1.05
Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development. Gene Expr Patterns (2004) 1.04
Differential cataractogenic potency of TGF-beta1, -beta2, and -beta3 and their expression in the postnatal rat eye. Invest Ophthalmol Vis Sci (1998) 1.04
Differential expression of crystallin genes during development of the rat eye lens. Dev Biol (1987) 1.03
Evidence that fibroblast growth factor promotes lens fibre differentiation. Curr Eye Res (1987) 1.03
Gamma S-crystallin of bovine and human eye lens: solution structure, stability and folding of the intact two-domain protein and its separate domains. Biophys Chem (2000) 1.03
Chromosomal arrangement of heat shock locus 2-48B in Drosophila hydei. Chromosoma (1982) 1.03
Nucleotide sequence of the rat gamma-crystallin gene region and comparison with an orthologous human region. Gene (1989) 1.03
Inhibition of transforming growth factor-beta-induced cataractous changes in lens explants by ocular media and alpha 2-macroglobulin. Invest Ophthalmol Vis Sci (1996) 1.02
The crystallin gene families. Ciba Found Symp (1984) 1.01
Estrogen protects lenses against cataract induced by transforming growth factor-beta (TGFbeta). J Exp Med (1997) 1.00
Induction of lens fibre differentiation by acidic and basic fibroblast growth factor (FGF). Growth Factors (1989) 1.00
Structural analysis of lens epithelial explants induced to differentiate into fibres by fibroblast growth factor (FGF). Exp Eye Res (1989) 1.00
A ribosome dissociation factor from rabbit reticulocytes (fluoride-E. coli ribosomes-initiation factors). Proc Natl Acad Sci U S A (1972) 0.99
Spatial and temporal expression of p57(KIP2) during murine lens development. Mech Dev (1999) 0.99
Localization of acidic fibroblast growth factor, basic fibroblast growth factor, and heparan sulphate proteoglycan in rat lens: implications for lens polarity and growth patterns. Invest Ophthalmol Vis Sci (1993) 0.99
Developmental expression of crystallin genes: in situ hybridization reveals a differential localization of specific mRNAs. Dev Biol (1987) 0.98
Intravitreal injection of TGFbeta induces cataract in rats. Invest Ophthalmol Vis Sci (1999) 0.97
Tgfbeta receptor expression in lens: implications for differentiation and cataractogenesis. Exp Eye Res (2001) 0.95
TGFbeta promotes Wnt expression during cataract development. Exp Eye Res (2008) 0.95
Heat-shock peptides in Drosophila hydei and their synthesis in vitro. Eur J Biochem (1978) 0.95
The unusual structure of heat shock locus 2-48B in Drosophila hydei. Mol Gen Genet (1984) 0.94
Tissue- and species-specific promoter elements of rat gamma-crystallin genes. Nucleic Acids Res (1990) 0.94
Onset of fibre differentiation in cultured rat lens epithelium under the influence of neural retina-conditioned medium. Exp Eye Res (1984) 0.93
Use of purified polysomes from rabbit reticulocytes in a specific test for initiation factors. Proc Natl Acad Sci U S A (1974) 0.93
Rise and fall of crystallin gene messenger levels during fibroblast growth factor induced terminal differentiation of lens cells. Dev Biol (1992) 0.93
DNA methylation as a regulatory mechanism in rat gamma-crystallin gene expression. Nucleic Acids Res (1991) 0.93
The gamma-crystallin gene families: sequence and evolutionary patterns. J Mol Evol (1988) 0.92
Rapid sequence divergence in a heat shock locus of Drosophila. Chromosoma (1980) 0.92
Lithium stabilizes the polarized lens epithelial phenotype and inhibits proliferation, migration, and epithelial mesenchymal transition. J Pathol (2006) 0.92
Differential expression of fibroblast growth factor receptors during rat lens morphogenesis and growth. Invest Ophthalmol Vis Sci (1997) 0.91
Deregulation of lens epithelial cell proliferation and differentiation during the development of TGFbeta-induced anterior subcapsular cataract. Dev Neurosci (2004) 0.91
Effects of differences in mitotic activity, stage of cell cycle, and degree of specialization of donor cells on nuclear transplantation in Xenopus laevis. Dev Biol (1975) 0.89
The role of fibroblast growth factor in eye lens development. Ann N Y Acad Sci (1991) 0.89
Intron insertions and deletions in the beta/gamma-crystallin gene family: the rat beta B1 gene. Proc Natl Acad Sci U S A (1986) 0.89
Differential effects of aqueous and vitreous on fiber differentiation and extracellular matrix accumulation in lens epithelial explants. Invest Ophthalmol Vis Sci (1995) 0.89
Ubiquitin-dependent pathway is up-regulated in differentiating lens cells. Exp Eye Res (1999) 0.89
IGF-1 enhancement of FGF-induced lens fiber differentiation in rats of different ages. Invest Ophthalmol Vis Sci (1993) 0.88
IGF enhancement of FGF-induced fibre differentiation and DNA synthesis in lens explants. Exp Eye Res (1996) 0.88
The roles of laminin and fibronectin in the development of the lens capsule. Curr Eye Res (1991) 0.88
Linkage between the beta B2 and beta B3 crystallin genes in man and rat: a remnant of an ancient beta-crystallin gene cluster. Gene (1987) 0.87
Regulation of expression within a gene family. The case of the rat gammaB- and gammaD-crystallin promoters. J Biol Chem (1998) 0.87
Expression of FGF-1 and FGF-2 mRNA during lens morphogenesis, differentiation and growth. Curr Eye Res (1997) 0.87
Susceptibility to TGFbeta2-induced cataract increases with aging in the rat. Invest Ophthalmol Vis Sci (2000) 0.87
Characterization of the rat gamma-crystallin gene family and its expression in the eye lens. J Mol Biol (1985) 0.87
Extralenticular expression of the rodent betaB2-crystallin gene. Exp Eye Res (1998) 0.86