Published in Neurotoxicology on June 09, 2005
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Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels. J Neurosci (2008) 1.30
The Kv2.1 K+ channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ. BMC Neurosci (2008) 1.27
Nitric oxide is an activity-dependent regulator of target neuron intrinsic excitability. Neuron (2011) 1.16
Subcellular localization of K+ channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity. Neuron (2015) 1.15
Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability. Proc Natl Acad Sci U S A (2011) 1.15
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Distinct modifications in Kv2.1 channel via chemokine receptor CXCR4 regulate neuronal survival-death dynamics. J Neurosci (2012) 0.99
Kv2 channels regulate firing rate in pyramidal neurons from rat sensorimotor cortex. J Physiol (2013) 0.99
Development of the sigma-1 receptor in C-terminals of motoneurons and colocalization with the N,N'-dimethyltryptamine forming enzyme, indole-N-methyl transferase. Neuroscience (2012) 0.99
Kv2 channel regulation of action potential repolarization and firing patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons. J Neurosci (2014) 0.98
Proteomic and bioinformatic analysis of epithelial tight junction reveals an unexpected cluster of synaptic molecules. Biol Direct (2006) 0.94
De novo KCNB1 mutations in infantile epilepsy inhibit repetitive neuronal firing. Sci Rep (2015) 0.91
Manipulating Kv4.2 identifies a specific component of hippocampal pyramidal neuron A-current that depends upon Kv4.2 expression. J Neurochem (2006) 0.90
Formation of Kv2.1-FAK complex as a mechanism of FAK activation, cell polarization and enhanced motility. J Cell Physiol (2008) 0.90
Mechanisms of Kv2.1 channel inhibition by celecoxib--modification of gating and channel block. Br J Pharmacol (2009) 0.89
The C-terminus of neuronal Kv2.1 channels is required for channel localization and targeting but not for NMDA-receptor-mediated regulation of channel function. Neuroscience (2012) 0.85
Kv2 dysfunction after peripheral axotomy enhances sensory neuron responsiveness to sustained input. Exp Neurol (2013) 0.84
Solution structure of GxTX-1E, a high-affinity tarantula toxin interacting with voltage sensors in Kv2.1 potassium channels . Biochemistry (2010) 0.84
Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2.1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure. PLoS One (2013) 0.84
Cell type-specific spatial and functional coupling between mammalian brain Kv2.1 K+ channels and ryanodine receptors. J Comp Neurol (2014) 0.83
Voltage-gated potassium channels in human immunodeficiency virus type-1 (HIV-1)-associated neurocognitive disorders. J Neuroimmune Pharmacol (2008) 0.83
GDF15 regulates Kv2.1-mediated outward K+ current through the Akt/mTOR signalling pathway in rat cerebellar granule cells. Biochem J (2014) 0.83
Role of the Sigma-1 receptor in Amyotrophic Lateral Sclerosis (ALS). J Pharmacol Sci (2015) 0.82
Developmental expression of Kv potassium channels at the axon initial segment of cultured hippocampal neurons. PLoS One (2012) 0.82
Regulation of neuronal proapoptotic potassium currents by the hepatitis C virus nonstructural protein 5A. J Neurosci (2012) 0.82
Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons. J Neurosci (2015) 0.81
Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels. Sci Rep (2015) 0.80
Major diversification of voltage-gated K+ channels occurred in ancestral parahoxozoans. Proc Natl Acad Sci U S A (2015) 0.78
Multifaceted modulation of K+ channels by protein-tyrosine phosphatase ε tunes neuronal excitability. J Biol Chem (2012) 0.78
Increased Kv1 channel expression may contribute to decreased sIPSC frequency following chronic inhibition of NR2B-containing NMDAR. Neuropsychopharmacology (2012) 0.78
Density of voltage-gated potassium channels is a bifurcation parameter in pyramidal neurons. J Neurophysiol (2014) 0.77
Gender-Specific Hippocampal Dysrhythmia and Aberrant Hippocampal and Cortical Excitability in the APPswePS1dE9 Model of Alzheimer's Disease. Neural Plast (2016) 0.77
Zn(2+) -induced Ca(2+) release via ryanodine receptors triggers calcineurin-dependent redistribution of cortical neuronal Kv2.1 K(+) channels. J Physiol (2016) 0.76
The Inhibitory Effects of Ca2+ Channel Blocker Nifedipine on Rat Kv2.1 Potassium Channels. PLoS One (2015) 0.76
Kv3.4 is modulated by HIF-1α to protect SH-SY5Y cells against oxidative stress-induced neural cell death. Sci Rep (2017) 0.75
The anticonvulsant retigabine suppresses neuronal KV2-mediated currents. Sci Rep (2016) 0.75
The Role of KV7.3 in Regulating Osteoblast Maturation and Mineralization. Int J Mol Sci (2016) 0.75
Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells. J Biol Chem (2015) 0.75
Physiological roles of Kv2 channels in entorhinal cortex layer II stellate cells revealed by Guangxitoxin-1E. J Physiol (2016) 0.75
When Inhibiting Repetitive Firing is Pro-Epileptic. Epilepsy Curr (2016) 0.75
AMIGO-Kv2.1 Potassium Channel Complex Is Associated With Schizophrenia-Related Phenotypes. Schizophr Bull (2015) 0.75
Chronic Ca(2+) influx through voltage-dependent Ca(2+) channels enhance delayed rectifier K(+) currents via activating Src family tyrosine kinase in rat hippocampal neurons. Korean J Physiol Pharmacol (2017) 0.75
Ps in the (channel) pod are not alike... Epilepsy Curr (2008) 0.75
Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma. BMC Neurosci (2017) 0.75
The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms. Front Cell Neurosci (2017) 0.75
Regulation of ion channel localization and phosphorylation by neuronal activity. Nat Neurosci (2004) 4.20
Localization and targeting of voltage-dependent ion channels in mammalian central neurons. Physiol Rev (2008) 2.90
Graded regulation of the Kv2.1 potassium channel by variable phosphorylation. Science (2006) 2.86
KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain. J Neurosci (2004) 2.31
Polarized distribution of ion channels within microdomains of the axon initial segment. J Comp Neurol (2007) 2.26
A fundamental role for KChIPs in determining the molecular properties and trafficking of Kv4.2 potassium channels. J Biol Chem (2003) 2.26
Antibodies as valuable neuroscience research tools versus reagents of mass distraction. J Neurosci (2006) 2.18
Functional specialization of the axon initial segment by isoform-specific sodium channel targeting. J Neurosci (2003) 2.04
Role of heteromultimers in the generation of myocardial transient outward K+ currents. Circ Res (2002) 1.68
Calcium- and metabolic state-dependent modulation of the voltage-dependent Kv2.1 channel regulates neuronal excitability in response to ischemia. J Neurosci (2005) 1.68
Bidirectional activity-dependent regulation of neuronal ion channel phosphorylation. J Neurosci (2006) 1.61
Immunolocalization of the Ca2+-activated K+ channel Slo1 in axons and nerve terminals of mammalian brain and cultured neurons. J Comp Neurol (2006) 1.59
Temporal and regional expression of NMDA receptor subunit NR3A in the mammalian brain. J Comp Neurol (2002) 1.57
The Kv2.1 C terminus can autonomously transfer Kv2.1-like phosphorylation-dependent localization, voltage-dependent gating, and muscarinic modulation to diverse Kv channels. J Neurosci (2006) 1.56
ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons. J Neurosci (2010) 1.47
The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice. Epilepsia (2012) 1.42
Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2. J Neurosci (2008) 1.41
Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment. J Cell Sci (2007) 1.39
Regulation of intrinsic excitability in hippocampal neurons by activity-dependent modulation of the KV2.1 potassium channel. Channels (Austin) (2009) 1.38
SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development. Neuron (2010) 1.35
RGS6, a modulator of parasympathetic activation in heart. Circ Res (2010) 1.32
Unanticipated region- and cell-specific downregulation of individual KChIP auxiliary subunit isotypes in Kv4.2 knock-out mouse brain. J Neurosci (2006) 1.32
Profiling the phospho-status of the BKCa channel alpha subunit in rat brain reveals unexpected patterns and complexity. Mol Cell Proteomics (2008) 1.29
Determinants of voltage-gated potassium channel surface expression and localization in Mammalian neurons. Crit Rev Biochem Mol Biol (2004) 1.28
Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expression. Proc Natl Acad Sci U S A (2007) 1.26
Competition between α-actinin and Ca²⁺-calmodulin controls surface retention of the L-type Ca²⁺ channel Ca(V)1.2. Neuron (2013) 1.23
Interdomain cytoplasmic interactions govern the intracellular trafficking, gating, and modulation of the Kv2.1 channel. J Neurosci (2008) 1.22
Use-dependent block by lidocaine but not amitriptyline is more pronounced in tetrodotoxin (TTX)-Resistant Nav1.8 than in TTX-sensitive Na+ channels. J Pharmacol Exp Ther (2006) 1.21
Extrasynaptic localization of inactivating calcium-activated potassium channels in mouse inner hair cells. J Neurosci (2004) 1.21
Structural consequences of Kcna1 gene deletion and transfer in the mouse hippocampus. Epilepsia (2007) 1.19
Dysregulation of axonal sodium channel isoforms after adult-onset chronic demyelination. J Neurosci Res (2003) 1.15
Light and electron microscopic analysis of KChIP and Kv4 localization in rat cerebellar granule cells. J Comp Neurol (2005) 1.10
Kv beta subunit oxidoreductase activity and Kv1 potassium channel trafficking. J Biol Chem (2001) 1.10
Clustering of neuronal potassium channels is independent of their interaction with PSD-95. J Cell Biol (2002) 1.06
Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting. J Cell Biol (2011) 1.06
Multisite phosphorylation of voltage-gated sodium channel alpha subunits from rat brain. J Proteome Res (2010) 1.04
Potassium channel phosphorylation in excitable cells: providing dynamic functional variability to a diverse family of ion channels. Physiology (Bethesda) (2008) 1.04
Novel clustering of sodium channel Na(v)1.1 with ankyrin-G and neurofascin at discrete sites in the inner plexiform layer of the retina. Mol Cell Neurosci (2005) 1.02
Distinct modifications in Kv2.1 channel via chemokine receptor CXCR4 regulate neuronal survival-death dynamics. J Neurosci (2012) 0.99
Activity-dependent phosphorylation of neuronal Kv2.1 potassium channels by CDK5. J Biol Chem (2011) 0.99
Mass spectrometry-based phosphoproteomics reveals multisite phosphorylation on mammalian brain voltage-gated sodium and potassium channels. Semin Cell Dev Biol (2010) 0.98
Proteomic analyses of K(v)2.1 channel phosphorylation sites determining cell background specific differences in function. Channels (Austin) (2007) 0.98
Convergent modulation of Kv4.2 channel alpha subunits by structurally distinct DPPX and KChIP auxiliary subunits. Biochemistry (2009) 0.97
Regulation of Kv1 channel trafficking by the mamba snake neurotoxin dendrotoxin K. FASEB J (2006) 0.96
Trafficking mechanisms underlying neuronal voltage-gated ion channel localization at the axon initial segment. Epilepsia (2012) 0.96
Diverse roles for auxiliary subunits in phosphorylation-dependent regulation of mammalian brain voltage-gated potassium channels. Pflugers Arch (2011) 0.96
Antibody-based validation of CNS ion channel drug targets. J Gen Physiol (2008) 0.95
A primary culture system for biochemical analyses of neuronal proteins. J Neurosci Methods (2004) 0.93
RNA editing of androgen receptor gene transcripts in prostate cancer cells. J Biol Chem (2008) 0.93
Regulator of G protein signaling 6 (RGS6) protein ensures coordination of motor movement by modulating GABAB receptor signaling. J Biol Chem (2011) 0.93
Analysis and functional implications of phosphorylation of neuronal voltage-gated potassium channels. Neurosci Lett (2010) 0.91
Distinct activation properties of the nuclear factor of activated T-cells (NFAT) isoforms NFATc3 and NFATc4 in neurons. J Biol Chem (2012) 0.91
The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gβγ-dependent modulation of TRPV1 channel. J Neurosci (2012) 0.90
Mossy fibre contact triggers the targeting of Kv4.2 potassium channels to dendrites and synapses in developing cerebellar granule neurons. J Neurochem (2004) 0.90
Mining recent brain proteomic databases for ion channel phosphosite nuggets. J Gen Physiol (2010) 0.89
Antibody-guided photoablation of voltage-gated potassium currents. J Gen Physiol (2013) 0.89
A unique ion channel clustering domain on the axon initial segment of mammalian neurons. J Comp Neurol (2014) 0.88
Complete 3D visualization of primate striosomes by KChIP1 immunostaining. J Comp Neurol (2009) 0.86
Benefits and pitfalls of secondary antibodies: why choosing the right secondary is of primary importance. PLoS One (2012) 0.86
Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2.1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure. PLoS One (2013) 0.84
Tissue preparation and immunostaining of mouse sensory nerve fibers innervating skin and limb bones. J Vis Exp (2012) 0.83
Cell type-specific spatial and functional coupling between mammalian brain Kv2.1 K+ channels and ryanodine receptors. J Comp Neurol (2014) 0.83
Characterization of zebrafish PSD-95 gene family members. J Neurobiol (2005) 0.82
The voltage-gated Na+ channel NaVBP co-localizes with methyl-accepting chemotaxis protein at cell poles of alkaliphilic Bacillus pseudofirmus OF4. Microbiology (2007) 0.82
TRPV1 is important for mechanical and heat sensitivity in uninjured animals and development of heat hypersensitivity after muscle inflammation. Pain (2012) 0.81
Calnexin regulates mammalian Kv1 channel trafficking. Biochem Biophys Res Commun (2004) 0.80
The electrically silent Kv6.4 subunit confers hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels. PLoS One (2012) 0.80
A SUMO-Phospho tag team for wrestling with potassium channel gating. J Gen Physiol (2011) 0.79
Abnormal trigeminal sensory processing in obese mice. Pain (2016) 0.78
Induction of thermal and mechanical hypersensitivity by parathyroid hormone-related peptide through upregulation of TRPV1 function and trafficking. Pain (2015) 0.77
The surprising catch of a voltage-gated potassium channel in a neuronal SNARE. Sci STKE (2007) 0.76
Cell cycle-dependent changes in localization and phosphorylation of the plasma membrane Kv2.1 K+ channel impact endoplasmic reticulum membrane contact sites in COS-1 cells. J Biol Chem (2016) 0.75
Kv1.1 takes a deTOR from the axon to the dendrite. Neuron (2006) 0.75
How native cells regulate their ion channels. Semin Cell Dev Biol (2010) 0.75