Published in Bioinformatics on June 01, 2005
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Resolving deconvolution ambiguity in gene alternative splicing. BMC Bioinformatics (2009) 0.94
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Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays. BMC Bioinformatics (2010) 0.83
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Prediction of alternatively skipped exons and splicing enhancers from exon junction arrays. BMC Genomics (2008) 0.78
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Integrated detection and population-genetic analysis of SNPs and copy number variation. Nat Genet (2008) 19.55
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nat Genet (2008) 15.89
GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat Genet (2002) 14.69
HITS-CLIP yields genome-wide insights into brain alternative RNA processing. Nature (2008) 14.17
Direct detection of DNA methylation during single-molecule, real-time sequencing. Nat Methods (2010) 9.75
Genotyping over 100,000 SNPs on a pair of oligonucleotide arrays. Nat Methods (2004) 9.52
Novel RNAs identified from an in-depth analysis of the transcriptome of human chromosomes 21 and 22. Genome Res (2004) 8.35
The genome of the mesopolyploid crop species Brassica rapa. Nat Genet (2011) 8.23
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet (2011) 6.98
Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases. Lancet Infect Dis (2013) 6.60
Nova regulates brain-specific splicing to shape the synapse. Nat Genet (2005) 6.58
Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res (2006) 6.45
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell (2009) 5.81
Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array. BMC Genomics (2006) 5.59
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Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing. Nature (2003) 5.04
Dynamic model based algorithms for screening and genotyping over 100 K SNPs on oligonucleotide microarrays. Bioinformatics (2005) 5.01
Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay. Genes Dev (2007) 4.75
Unusual intron conservation near tissue-regulated exons found by splicing microarrays. PLoS Comput Biol (2006) 4.63
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature (2012) 4.37
A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity. Proc Natl Acad Sci U S A (2007) 4.35
The Taverna workflow suite: designing and executing workflows of Web Services on the desktop, web or in the cloud. Nucleic Acids Res (2013) 4.32
Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature (2009) 4.21
SLAM: cross-species gene finding and alignment with a generalized pair hidden Markov model. Genome Res (2003) 4.17
Evaluation of genetic variation contributing to differences in gene expression between populations. Am J Hum Genet (2008) 4.01
Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat Rev Cancer (2009) 3.90
A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle. Mol Cell (2003) 3.88
p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. Genes Dev (2005) 3.88
The ecology of seamounts: structure, function, and human impacts. Ann Rev Mar Sci (2010) 3.78
Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity. PLoS Genet (2006) 3.51
Single-layer MoS2 phototransistors. ACS Nano (2011) 3.43
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci (2010) 3.41
Genome-wide mapping of methylated adenine residues in pathogenic Escherichia coli using single-molecule real-time sequencing. Nat Biotechnol (2012) 3.39
Genetic architecture of transcript-level variation in humans. Am J Hum Genet (2008) 3.36
Probe selection for high-density oligonucleotide arrays. Proc Natl Acad Sci U S A (2003) 3.31
Detection and measurement of alternative splicing using splicing-sensitive microarrays. Methods (2005) 3.21
The methylomes of six bacteria. Nucleic Acids Res (2012) 3.19
Human genomic deletions mediated by recombination between Alu elements. Am J Hum Genet (2006) 3.15
Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy. Nat Struct Mol Biol (2010) 3.07
Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach. Am J Hum Genet (2007) 3.05
Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14. BMC Genet (2005) 3.04
Gene structure-based splice variant deconvolution using a microarray platform. Bioinformatics (2003) 2.97
Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Res (2008) 2.97
Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition. Genes Dev (2005) 2.83
A new family of potent AB(5) cytotoxins produced by Shiga toxigenic Escherichia coli. J Exp Med (2004) 2.81
Heritability of alternative splicing in the human genome. Genome Res (2007) 2.76
Changing trends in antimicrobial resistance and serotypes of Streptococcus pneumoniae isolates in Asian countries: an Asian Network for Surveillance of Resistant Pathogens (ANSORP) study. Antimicrob Agents Chemother (2012) 2.65
Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris. Genome Res (2005) 2.65
Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. PLoS One (2009) 2.62
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell (2012) 2.54
A Drosophila resource of transgenic RNAi lines for neurogenetics. Genetics (2009) 2.45
Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J Proteome Res (2008) 2.44
Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate. J Virol (2002) 2.43
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data. Nucleic Acids Res (2010) 2.41
c-Myc is required for maintenance of glioma cancer stem cells. PLoS One (2008) 2.41
In vitro anti-cancer activity and structure-activity relationships of natural products isolated from fruits of Panax ginseng. Cancer Chemother Pharmacol (2006) 2.33
Agricultural origins and the isotopic identity of domestication in northern China. Proc Natl Acad Sci U S A (2009) 2.32
Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics (2011) 2.31
Spread of methicillin-resistant Staphylococcus aureus between the community and the hospitals in Asian countries: an ANSORP study. J Antimicrob Chemother (2011) 2.30
QALY maximisation and people's preferences: a methodological review of the literature. Health Econ (2005) 2.29
Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature (2012) 2.26
The Drosophila melanogaster transcriptome by paired-end RNA sequencing. Genome Res (2010) 2.25
Novel rank-based statistical methods reveal microRNAs with differential expression in multiple cancer types. PLoS One (2009) 2.21
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB. Nat Struct Mol Biol (2010) 2.19
Gaussian Bare-Bones Differential Evolution. IEEE Trans Cybern (2013) 2.08
Identification of pathways for atherosclerosis in mice: integration of quantitative trait locus analysis and global gene expression data. Circ Res (2007) 2.07
Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation. Cancer Res (2004) 2.07
High prevalence of macrolide resistance in Mycoplasma pneumoniae isolates from adult and adolescent patients with respiratory tract infection in China. Clin Infect Dis (2010) 2.02
Solution state characterization of amyloid beta-derived diffusible ligands. Biochemistry (2006) 1.96
Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration. Nat Genet (2012) 1.96
Identification of common genetic variants that account for transcript isoform variation between human populations. Hum Genet (2008) 1.96
COPI activity coupled with fatty acid biosynthesis is required for viral replication. PLoS Pathog (2006) 1.95
Applications of generalized pair hidden Markov models to alignment and gene finding problems. J Comput Biol (2002) 1.94
A correlation with exon expression approach to identify cis-regulatory elements for tissue-specific alternative splicing. Nucleic Acids Res (2007) 1.94
Primate-specific microRNA-637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting signal transducer and activator of transcription 3 signaling. Hepatology (2011) 1.93
Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation. Proc Natl Acad Sci U S A (2010) 1.93
Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment. Anesthesiology (2013) 1.93
MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53. J Biol Chem (2004) 1.93
Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner. J Biol Chem (2005) 1.92
Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. Antimicrob Agents Chemother (2008) 1.91
GO-Elite: a flexible solution for pathway and ontology over-representation. Bioinformatics (2012) 1.91
Meta-analysis of vitamin D, calcium and the prevention of breast cancer. Breast Cancer Res Treat (2009) 1.90
Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine. Nat Methods (2011) 1.90