Extracellular cyclophilins contribute to the regulation of inflammatory responses.

PubWeight™: 1.82‹?› | Rank: Top 3%

🔗 View Article (PMC 2862457)

Published in J Immunol on July 01, 2005

Authors

Kamalpreet Arora1, William M Gwinn, Molly A Bower, Alan Watson, Ifeanyi Okwumabua, H Robson MacDonald, Michael I Bukrinsky, Stephanie L Constant

Author Affiliations

1: Department of Microbiology and Tropical Medicine, George Washington University, Washington, D.C. 20037, USA.

Articles citing this

Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted. Physiol Rev (2007) 2.14

CD147 immunoglobulin superfamily receptor function and role in pathology. Exp Mol Pathol (2007) 1.77

Identity and transfer of male reproductive gland proteins of the dengue vector mosquito, Aedes aegypti: potential tools for control of female feeding and reproduction. Insect Biochem Mol Biol (2007) 1.69

Novel approach to inhibit asthma-mediated lung inflammation using anti-CD147 intervention. J Immunol (2006) 1.56

Liver proteomics for therapeutic drug discovery: inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure. Crit Care Med (2007) 1.54

Dealing with the family: CD147 interactions with cyclophilins. Immunology (2006) 1.46

Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics. Clin Exp Immunol (2010) 1.43

Stress wars: the direct role of host and bacterial molecular chaperones in bacterial infection. Infect Immun (2006) 1.35

Cyclophilin D in mitochondrial pathophysiology. Biochim Biophys Acta (2009) 1.27

Cyclophilin A: a key player for human disease. Cell Death Dis (2013) 1.26

Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A. J Leukoc Biol (2007) 1.23

Solution characterization of the extracellular region of CD147 and its interaction with its enzyme ligand cyclophilin A. J Mol Biol (2009) 1.21

Metabolic reprogramming and metabolic dependency in T cells. Immunol Rev (2012) 1.18

Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice. J Exp Med (2010) 1.18

The mitochondrial permeability transition from yeast to mammals. FEBS Lett (2010) 1.17

The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects in Col6a1-/- myopathic mice. Br J Pharmacol (2009) 1.16

Targeting the chemotactic function of CD147 reduces collagen-induced arthritis. Immunology (2008) 1.12

Cyclophilin A release as a biomarker of necrotic cell death. Cell Death Differ (2010) 1.02

Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion. Arterioscler Thromb Vasc Biol (2011) 1.02

Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB. Neuroscience (2013) 0.97

A cell-impermeable cyclosporine A derivative reduces pathology in a mouse model of allergic lung inflammation. J Immunol (2010) 0.96

Role of cyclophilin A from brains of prion-infected mice in stimulation of cytokine release by microglia and astroglia in vitro. J Biol Chem (2011) 0.95

The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion. J Am Soc Nephrol (2009) 0.95

Hepatitis B virus (HBV) surface antigen interacts with and promotes cyclophilin a secretion: possible link to pathogenesis of HBV infection. J Virol (2010) 0.94

Microbial peptidyl-prolyl cis/trans isomerases (PPIases): virulence factors and potential alternative drug targets. Microbiol Mol Biol Rev (2014) 0.93

Isoform-specific inhibition of cyclophilins. Biochemistry (2009) 0.92

Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB. J Neurooncol (2010) 0.92

Structural, biochemical, and in vivo characterization of the first virally encoded cyclophilin from the Mimivirus. J Mol Biol (2007) 0.91

Protein profiles of peripheral blood mononuclear cells are useful for differential diagnosis of ulcerative colitis and Crohn's disease. J Gastroenterol (2010) 0.90

Cyclophilin A (CyPA) induces chemotaxis independent of its peptidylprolyl cis-trans isomerase activity: direct binding between CyPA and the ectodomain of CD147. J Biol Chem (2011) 0.89

Downregulation of cyclophilin A by siRNA diminishes non-small cell lung cancer cell growth and metastasis via the regulation of matrix metallopeptidase 9. BMC Cancer (2012) 0.88

Cyclophilins as modulators of viral replication. Viruses (2013) 0.88

Contribution of cyclophilin A to the regulation of inflammatory processes in rheumatoid arthritis. J Clin Immunol (2009) 0.88

Cyclophilin A from Schistosoma japonicum promotes a Th2 response in mice. Parasit Vectors (2013) 0.88

Blocking cyclophilins in the chronic phase of asthma reduces the persistence of leukocytes and disease reactivation. Am J Respir Cell Mol Biol (2011) 0.87

Selection of suitable housekeeping genes for real-time quantitative PCR in CD4(+) lymphocytes from asthmatics with or without depression. PLoS One (2012) 0.87

Cyclophilin A cooperates with MIP-2 to augment neutrophil migration. J Inflamm Res (2011) 0.86

Basigin-mediated gene expression changes in mouse uterine stromal cells during implantation. Endocrinology (2008) 0.86

The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis. Stem Cell Res Ther (2012) 0.85

The level of CD147 expression correlates with cyclophilin-induced signalling and chemotaxis. BMC Res Notes (2011) 0.83

Keratinocyte secretion of cyclophilin B via the constitutive pathway is regulated through its cyclosporin-binding site. J Invest Dermatol (2011) 0.82

Involvement of HAb18G/CD147 in T cell activation and immunological synapse formation. J Cell Mol Med (2010) 0.81

Expression of basigin in reproductive tissues of estrogen receptor-{alpha} or -{beta} null mice. Reproduction (2010) 0.80

Extracellular cyclophilin levels associate with parameters of asthma in phenotypic clusters. J Asthma (2011) 0.80

The roles of CD147 and/or cyclophilin A in kidney diseases. Mediators Inflamm (2014) 0.80

Synthesis of heparan sulfate with cyclophilin B-binding properties is determined by cell type-specific expression of sulfotransferases. J Biol Chem (2009) 0.79

Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction. Am J Pathol (2011) 0.79

Roles of Prolyl Isomerases in RNA-Mediated Gene Expression. Biomolecules (2015) 0.78

Functions of cyclophilin A in atherosclerosis. Exp Clin Cardiol (2013) 0.78

Targeting extracellular cyclophilins ameliorates disease progression in experimental biliary atresia. Mol Med (2015) 0.77

Identification of HIV inhibitors guided by free energy perturbation calculations. Curr Pharm Des (2012) 0.77

Functional analysis of Leishmania major cyclophilin. Int J Parasitol (2007) 0.77

Function of CD147 in atherosclerosis and atherothrombosis. J Cardiovasc Transl Res (2015) 0.77

Cyclophilin A is associated with peripheral artery disease and chronic kidney disease in geriatrics: The Tianliao Old People (TOP) study. Sci Rep (2015) 0.77

Lack of evidence for caveolin-1 and CD147 interaction before and after bleomycin-induced lung injury. Histochem Cell Biol (2006) 0.76

Extracellular cyclophilins in health and disease. Biochim Biophys Acta (2014) 0.76

Extracellular cyclophilin A possesses chemotaxic activity in cattle. Vet Res (2015) 0.76

Chemotactic Activity of Cyclophilin A in the Skin Mucus of Yellow Catfish (Pelteobagrus fulvidraco) and Its Active Site for Chemotaxis. Int J Mol Sci (2016) 0.75

Decrease in plasma cyclophilin A concentration at 1 month after myocardial infarction predicts better left ventricular performance and synchronicity at 6 months: a pilot study in patients with ST elevation myocardial infarction. Int J Biol Sci (2015) 0.75

Participation of 3-O-sulfated heparan sulfates in the protection of macrophages by herpes simplex virus-1 glycoprotein D and cyclophilin B against apoptosis. FEBS Open Bio (2016) 0.75

Spongionella Secondary Metabolites, Promising Modulators of Immune Response through CD147 Receptor Modulation. Front Immunol (2016) 0.75

Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus. Cardiovasc Diabetol (2016) 0.75

Cyclophilin A protects mice against infection by influenza A virus. Sci Rep (2016) 0.75

Inhibition of synovitis and joint destruction by a new single domain antibody specific for cyclophilin A in two different mouse models of rheumatoid arthritis. Arthritis Res Ther (2013) 0.75

Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) promotes lung fibroblast proliferation, survival and differentiation to myofibroblasts. Respir Res (2016) 0.75

Functional annotation of proteomic data from chicken heterophils and macrophages induced by carbon nanotube exposure. Int J Mol Sci (2014) 0.75

Proteomic Alterations in B Lymphocytes of Sensitized Mice in a Model of Chemical-Induced Asthma. PLoS One (2015) 0.75

Articles cited by this

Chemokine networks in vivo: involvement of C-X-C and C-C chemokines in neutrophil extravasation in vivo in response to TNF-alpha. J Immunol (1997) 2.51

Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases. Am J Physiol Lung Cell Mol Physiol (2003) 2.20

Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages. Proc Natl Acad Sci U S A (1992) 2.20

Cyclophilin A is a secreted growth factor induced by oxidative stress. Circ Res (2000) 2.09

Host cyclophilin A mediates HIV-1 attachment to target cells via heparans. EMBO J (1999) 1.98

Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus (HIV) type 1: interference with HIV protein-cyclophilin A interactions. J Virol (1995) 1.96

Active site residues of cyclophilin A are crucial for its signaling activity via CD147. J Biol Chem (2002) 1.96

Leukocyte chemotactic activity of cyclophilin. J Biol Chem (1992) 1.63

Cyclophilins: unexpected messengers in intercellular communications. Trends Immunol (2002) 1.43

Inhibition of murine neutrophil recruitment in vivo by CXC chemokine receptor antagonists. J Immunol (1999) 1.43

Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2002) 1.32

Increased expression of extracellular matrix metalloproteinase inducer in rheumatoid synovium. Arthritis Rheum (2000) 1.31

Presence of cyclophilin A in synovial fluids of patients with rheumatoid arthritis. J Exp Med (1997) 1.31

Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrix. Proc Natl Acad Sci U S A (2002) 1.30

Elevated serum cyclophilin levels in patients with severe sepsis. J Clin Immunol (1997) 1.28

Expression of extracellular matrix metalloproteinase inducer and enhancement of the production of matrix metalloproteinases in rheumatoid arthritis. Arthritis Rheum (2002) 1.25

Hypoxia followed by reoxygenation induces secretion of cyclophilin A from cultured rat cardiac myocytes. Biochem Biophys Res Commun (2004) 1.12

A role for CD147 in thymic development. J Immunol (2002) 1.09

Inhibition of inflammatory responses by ambroxol, a mucolytic agent, in a murine model of acute lung injury induced by lipopolysaccharide. Intensive Care Med (2003) 1.05

Involvement of two classes of binding sites in the interactions of cyclophilin B with peripheral blood T-lymphocytes. Biochem J (1998) 0.96

Unavailability of CD147 leads to selective erythrocyte trapping in the spleen. Blood (2001) 0.95

Role and Regulation of Chemokines in Rodent Models of Lung Inflammation. ILAR J (1999) 0.85

Articles by these authors

NKT cells: what's in a name? Nat Rev Immunol (2004) 7.84

Notch regulation of lymphocyte development and function. Nat Immunol (2004) 3.39

Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. J Exp Med (2004) 3.16

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. Immunity (2002) 2.83

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity. Cell Stem Cell (2008) 2.83

Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood (2004) 2.44

Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation. Immunity (2010) 2.29

MyD88-dependent induction of allergic Th2 responses to intranasal antigen. J Clin Invest (2005) 2.20

Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment. Science (2008) 2.10

Precursors of functional MHC class I- or class II-restricted CD8alphaalpha(+) T cells are positively selected in the thymus by agonist self-peptides. Immunity (2002) 1.83

The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells. J Immunol (2002) 1.71

A prospective study of the use of cryosurgery for the treatment of actinic keratoses. Int J Dermatol (2004) 1.66

Regulation of innate and adaptive immunity by Notch. Nat Rev Immunol (2013) 1.58

Novel approach to inhibit asthma-mediated lung inflammation using anti-CD147 intervention. J Immunol (2006) 1.56

Liver proteomics for therapeutic drug discovery: inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure. Crit Care Med (2007) 1.54

In vivo administration of a lentiviral vaccine targets DCs and induces efficient CD8(+) T cell responses. J Clin Invest (2003) 1.54

Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia. Nat Immunol (2010) 1.49

Thymic selection generates a large T cell pool recognizing a self-peptide in humans. J Exp Med (2002) 1.44

Cutting edge: influence of the TCR Vbeta domain on the selection of semi-invariant NKT cells by endogenous ligands. J Immunol (2006) 1.43

Cutting edge: influence of the TCR V beta domain on the avidity of CD1d:alpha-galactosylceramide binding by invariant V alpha 14 NKT cells. J Immunol (2003) 1.41

In vitro and in vivo characterization of anthrax anti-protective antigen and anti-lethal factor monoclonal antibodies after passive transfer in a mouse lethal toxin challenge model to define correlates of immunity. Infect Immun (2007) 1.33

Bronchial and bronchiolar fibrosis in rats exposed to 2,3-pentanedione vapors: implications for bronchiolitis obliterans in humans. Toxicol Pathol (2012) 1.31

Selective requirement for c-Myc at an early stage of V(alpha)14i NKT cell development. J Immunol (2009) 1.29

Mineral metabolism and vascular damage in children on dialysis. J Am Soc Nephrol (2007) 1.27

Efficient transduction of dendritic cells and induction of a T-cell response by third-generation lentivectors. Hum Gene Ther (2002) 1.27

Cutting edge: genetic variation influences Fc epsilonRI-induced mast cell activation and allergic responses. J Immunol (2007) 1.26

Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A. J Leukoc Biol (2007) 1.23

Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes. J Exp Med (2013) 1.21

Severe airway epithelial injury, aberrant repair and bronchiolitis obliterans develops after diacetyl instillation in rats. PLoS One (2011) 1.15

NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells. J Immunol (2012) 1.14

Notch signaling in T- and B-cell development. Curr Opin Immunol (2004) 1.14

Targeting the chemotactic function of CD147 reduces collagen-induced arthritis. Immunology (2008) 1.12

Nrf2/ARE regulated antioxidant gene expression in endothelial and smooth muscle cells in oxidative stress: implications for atherosclerosis and preeclampsia. Sheng Li Xue Bao (2007) 1.11

Dioxin- and POP-contaminated sites--contemporary and future relevance and challenges: overview on background, aims and scope of the series. Environ Sci Pollut Res Int (2008) 1.10

A role for CD147 in thymic development. J Immunol (2002) 1.09

c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis. Blood (2006) 1.06

Hypoxia in the thymus: role of oxygen tension in thymocyte survival. Am J Physiol Heart Circ Physiol (2002) 1.05

A secreted protein from the human hookworm necator americanus binds selectively to NK cells and induces IFN-gamma production. J Immunol (2004) 1.05

Immunobiology of hookworm infection. FEMS Immunol Med Microbiol (2005) 1.04

Human invariant V alpha 24-J alpha Q TCR supports the development of CD1d-dependent NK1.1+ and NK1.1- T cells in transgenic mice. J Immunol (2003) 1.04

Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion. Arterioscler Thromb Vasc Biol (2011) 1.02

Mouse CD11c(+) B220(+) Gr1(+) plasmacytoid dendritic cells develop independently of the T-cell lineage. Blood (2002) 1.00

IgA-producing plasma cells originate from germinal centers that are induced by B-cell receptor engagement in humans. Gastroenterology (2010) 0.98

Leishmania pifanoi pathogenesis: selective lack of a local cutaneous response in the absence of circulating antibody. Infect Immun (2002) 0.97

Redundant Notch1 and Notch2 signaling is necessary for IFNγ secretion by T helper 1 cells during infection with Leishmania major. PLoS Pathog (2012) 0.97

The role of Notch signaling during hematopoietic lineage commitment. Immunol Rev (2002) 0.97

A cell-impermeable cyclosporine A derivative reduces pathology in a mouse model of allergic lung inflammation. J Immunol (2010) 0.96

Notch signaling in hematopoiesis and lymphopoiesis: lessons from Drosophila. Bioessays (2005) 0.96

Ligand-dependent inhibition of CD1d-restricted NKT cell development in mice transgenic for the activating receptor Ly49D. J Exp Med (2003) 0.96

Genetic ablation of the alpha 6-integrin subunit in Tie1Cre mice enhances tumour angiogenesis. J Pathol (2010) 0.95

Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60. J Biol Chem (2005) 0.93

Necator americanus: the Na-ASP-2 protein secreted by the infective larvae induces neutrophil recruitment in vivo and in vitro. Exp Parasitol (2007) 0.93

Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells. J Immunol (2008) 0.93

Isoform-specific inhibition of cyclophilins. Biochemistry (2009) 0.92

Lung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromium. Toxicol Appl Pharmacol (2008) 0.92

Lung inflammation, injury, and proliferative response after repetitive particulate hexavalent chromium exposure. Environ Health Perspect (2009) 0.92

Blue lunulae: argyria and hypercopprecaemia. Australas J Dermatol (2007) 0.91

IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro. PLoS One (2012) 0.90

Vpr-host interactions during HIV-1 viral life cycle. J Neuroimmune Pharmacol (2011) 0.90

A cyclosporin derivative discriminates between extracellular and intracellular cyclophilins. Angew Chem Int Ed Engl (2010) 0.89

Side effects of aminoglycosides on the kidney, ear and balance in cystic fibrosis. Thorax (2010) 0.88

Notch signaling regulates follicular helper T cell differentiation. J Immunol (2013) 0.87

c-Myc controls the development of CD8alphaalpha TCRalphabeta intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15-dependent survival. Blood (2010) 0.87

A systematic review of the evidence for 'myths and misconceptions' in acne management: diet, face-washing and sunlight. Fam Pract (2005) 0.87

Blocking cyclophilins in the chronic phase of asthma reduces the persistence of leukocytes and disease reactivation. Am J Respir Cell Mol Biol (2011) 0.87

Cyclophilin A cooperates with MIP-2 to augment neutrophil migration. J Inflamm Res (2011) 0.86

Integrating Fusarium oxysporum f. sp. strigae into cereal cropping systems in Africa. Pest Manag Sci (2009) 0.85

Paradigms of notch signaling in mammals. Int J Hematol (2005) 0.85

A nonproliferating parvovirus vaccine vector elicits sustained, protective humoral immunity following a single intravenous or intranasal inoculation. J Virol (2004) 0.84

TCRgamma silencing during alphabeta T cell development depends upon pre-TCR-induced proliferation. J Immunol (2006) 0.84

NK cell tolerance: revisiting the central dogma. Nat Immunol (2005) 0.84

Ly49D engagement on T lymphocytes induces TCR-independent activation and CD8 effector functions that control tumor growth. J Immunol (2009) 0.83

Review Article: Persistent organic pollutants and landfills - a review of past experiences and future challenges. Waste Manag Res (2011) 0.83

Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil. Infect Immun (2008) 0.83

PFOS and PFC releases and associated pollution from a PFC production plant in Minnesota (USA). Environ Sci Pollut Res Int (2012) 0.82

Diacetyl induces amphiregulin shedding in pulmonary epithelial cells and in experimental bronchiolitis obliterans. Am J Respir Cell Mol Biol (2014) 0.82

Functional education of invariant NKT cells by dendritic cell tuning of SHP-1. J Immunol (2013) 0.81

Building consensus on transition of transplant patients from paediatric to adult healthcare. Arch Dis Child (2010) 0.81

VBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in mice. PLoS One (2013) 0.81

Significantly reduced CCR5-tropic HIV-1 replication in vitro in cells from subjects previously immunized with Vaccinia Virus. BMC Immunol (2010) 0.80

Point of care monitoring of hemodialysis patients with a breath ammonia measurement device based on printed polyaniline nanoparticle sensors. Anal Chem (2013) 0.80

Tests and evaluation of a variable focus liquid lens for curvature wavefront sensors in astronomy. Appl Opt (2013) 0.79

TCR-alpha CDR3 loop audition regulates positive selection. J Immunol (2006) 0.79

Chronic kidney disease-mineral bone disorder (CKD-MBD) management and associated cost in an Irish haemodialysis cohort. Nephrol Dial Transplant (2011) 0.78

Arteriovenous fistula buttonhole cannulation: early experience in an Irish haemodialysis unit. Nephrol Dial Transplant (2011) 0.78

Analysis of viral and cellular proteins in HIV-1 reverse transcription complexes by co-immunoprecipitation. Methods Mol Biol (2009) 0.78

Exposure to particulate hexavalent chromium exacerbates allergic asthma pathology. Toxicol Appl Pharmacol (2011) 0.78

Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts. Int Immunol (2011) 0.78

Hospital--school liaison: perspectives of health and education professionals supporting children with renal transplants. J Child Health Care (2008) 0.78

Ly49D-mediated ITAM signaling in immature thymocytes impairs development by bypassing the pre-TCR checkpoint. J Immunol (2011) 0.78