Published in Physiol Rev on July 01, 2005
The Concise Guide to PHARMACOLOGY 2013/14: ion channels. Br J Pharmacol (2013) 3.03
Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels. J Physiol (2008) 2.66
Ion channels and cancer. J Membr Biol (2005) 2.56
Inhibition of Ca2+-activated Cl- channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea. FASEB J (2010) 1.71
The TMEM16 protein family: a new class of chloride channels? Biophys J (2009) 1.68
International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels. Pharmacol Rev (2011) 1.67
Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels? Acta Pharmacol Sin (2011) 1.64
Calcium-dependent chloride conductance in epithelia: is there a contribution by Bestrophin? Pflugers Arch (2007) 1.47
Bestrophin-1 enables Ca2+-activated Cl- conductance in epithelia. J Biol Chem (2006) 1.31
The role of CLCA proteins in inflammatory airway disease. Annu Rev Physiol (2009) 1.26
Identification of novel candidate genes involved in mineralization of dental enamel by genome-wide transcript profiling. J Cell Physiol (2012) 1.24
The epithelial anion transporter pendrin is induced by allergy and rhinovirus infection, regulates airway surface liquid, and increases airway reactivity and inflammation in an asthma model. J Immunol (2008) 1.21
Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation. J Biol Chem (2012) 1.07
Calmodulin contributes to gating control in olfactory calcium-activated chloride channels. J Gen Physiol (2006) 1.03
Gene-expression analysis of early- and late-maturation-stage rat enamel organ. Eur J Oral Sci (2011) 1.00
Murine mCLCA6 is an integral apical membrane protein of non-goblet cell enterocytes and co-localizes with the cystic fibrosis transmembrane conductance regulator. J Histochem Cytochem (2008) 0.98
Human ClCa1 modulates anionic conduction of calcium-dependent chloride currents. J Physiol (2009) 0.97
Differential expression of calcium-activated chloride channels (CLCA) gene family members in the small intestine of cystic fibrosis mouse models. Histochem Cell Biol (2006) 0.90
A variant of the Ca2+-activated Cl channel Best3 is expressed in mouse exocrine glands. J Membr Biol (2008) 0.88
Novel Roles for Chloride Channels, Exchangers, and Regulators in Chronic Inflammatory Airway Diseases. Mediators Inflamm (2015) 0.87
Lymphatic endothelial murine chloride channel calcium-activated 1 is a ligand for leukocyte LFA-1 and Mac-1. J Immunol (2010) 0.86
Secreted hCLCA1 is a signaling molecule that activates airway macrophages. PLoS One (2013) 0.86
Functional assembly and purinergic activation of bestrophins. Pflugers Arch (2009) 0.86
Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1. J Physiol (2009) 0.85
Increased human Ca²⁺-activated Cl⁻ channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients. Respir Res (2012) 0.85
mCLCA4 ER processing and secretion requires luminal sorting motifs. Am J Physiol Cell Physiol (2008) 0.83
Computational molecular biology approaches to ligand-target interactions. HFSP J (2009) 0.82
CLCAs - a family of metalloproteases of intriguing phylogenetic distribution and with cases of substituted catalytic sites. PLoS One (2013) 0.82
Molecular expression and functional involvement of the bovine calcium-activated chloride channel 1 (bCLCA1) in apical HCO3- permeability of bovine corneal endothelium. Exp Eye Res (2006) 0.82
Structure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channels. Front Physiol (2014) 0.81
Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokers. BMC Med Genomics (2012) 0.81
Impaired autoproteolytic cleavage of mCLCA6, a murine integral membrane protein expressed in enterocytes, leads to cleavage at the plasma membrane instead of the endoplasmic reticulum. Mol Cells (2012) 0.79
Comparative Proteomics of Ovarian Cancer Aggregate Formation Reveals an Increased Expression of Calcium-activated Chloride Channel Regulator 1 (CLCA1). J Biol Chem (2015) 0.78
The porcine chloride channel calcium-activated family member pCLCA4a mirrors lung expression of the human hCLCA4. J Histochem Cytochem (2012) 0.78
The multifunctional role of the pallilysin-associated Treponema pallidum protein, Tp0750, in promoting fibrinolysis and extracellular matrix component degradation. Mol Microbiol (2014) 0.78
MARCKS-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging. Aging Cell (2015) 0.78
Cellular distribution and subcellular localization of mCLCA1/2 in murine gastrointestinal epithelia. J Histochem Cytochem (2010) 0.78
The Lymphatic Endothelial mCLCA1 Antibody Induces Proliferation and Growth of Lymph Node Lymphatic Sinuses. PLoS One (2016) 0.76
Metaproteomics reveals functional shifts in microbial and human proteins during a preterm infant gut colonization case. Proteomics (2015) 0.76
CLCA splicing isoform associated with adhesion through β1-integrin and its scaffolding protein: specific expression in undifferentiated epithelial cells. J Biol Chem (2013) 0.75
Isolation and Expression Profile of the Ca-Activated Chloride Channel-like Membrane Protein 6 Gene in Xenopus laevis. Lab Anim Res (2011) 0.75
Increased TMEM16A Involved in Alveolar Fluid Clearance After Lipopolysaccharide Stimulation. Inflammation (2016) 0.75
CLCA1 suppresses colorectal cancer aggressiveness via inhibition of the Wnt/beta-catenin signaling pathway. Cell Commun Signal (2017) 0.75
The calcium-dependent chloride conductance mediator pCLCA1. Am J Physiol Cell Physiol (2002) 0.89
pCLCA1 becomes a cAMP-dependent chloride conductance mediator in Caco-2 cells. Biochem Biophys Res Commun (2002) 0.88
CLCA protein and chloride transport in canine retinal pigment epithelium. Am J Physiol Cell Physiol (2003) 0.84
pCLCA1 lacks inherent chloride channel activity in an epithelial colon carcinoma cell line. Am J Physiol Gastrointest Liver Physiol (2004) 0.84
Complex expression and localization of inactivating Kv channels in cultured hippocampal astrocytes. J Neurophysiol (2005) 0.81
Differential mitochondrial DNA and gene expression in inherited retinal dysplasia in miniature Schnauzer dogs. Invest Ophthalmol Vis Sci (2006) 0.78
Mitochondrial transcription factor A (Tfam) gene sequencing and mitochondrial evaluation in inherited retinal dysplasia in miniature schnauzer dogs. Can J Vet Res (2011) 0.75
Differences in expression of retinal pigment epithelium mRNA between normal canines. Can J Vet Res (2004) 0.75
Relative quantification of white blood cell mitochondrial DNA and assessment of mitochondria by use of transmission electron microscopy in English Springer Spaniels with and without retinal dysplasia. Am J Vet Res (2010) 0.75