Published in Neuropsychopharmacology on February 01, 2006
The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons? J Physiol (2006) 3.97
Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. PLoS Biol (2007) 2.34
The orexin system regulates alcohol-seeking in rats. Br J Pharmacol (2006) 2.30
Orexin A/hypocretin-1 selectively promotes motivation for positive reinforcers. J Neurosci (2009) 2.02
The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system. Eur J Neurosci (2009) 1.59
Complex movement disorders at disease onset in childhood narcolepsy with cataplexy. Brain (2011) 1.35
Multiple roles for orexin/hypocretin in addiction. Prog Brain Res (2012) 1.26
Reinstatement of cocaine seeking by hypocretin (orexin) in the ventral tegmental area: independence from the local corticotropin-releasing factor network. Biol Psychiatry (2009) 1.25
Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration. Psychopharmacology (Berl) (2010) 1.17
Hypocretin /orexin preferentially activates caudomedial ventral tegmental area dopamine neurons. Eur J Neurosci (2008) 1.13
Overconsumption of dietary fat and alcohol: mechanisms involving lipids and hypothalamic peptides. Physiol Behav (2007) 1.13
A history of bingeing on fat enhances cocaine seeking and taking. Behav Neurosci (2011) 1.13
Role of orexin/hypocretin in dependence and addiction. Brain Res (2009) 1.12
Activation of afferents to the ventral tegmental area in response to acute amphetamine: a double-labelling study. Eur J Neurosci (2007) 1.08
Orexin/hypocretin modulates response of ventral tegmental dopamine neurons to prefrontal activation: diurnal influences. J Neurosci (2010) 1.07
Orexin mediates the expression of precipitated morphine withdrawal and concurrent activation of the nucleus accumbens shell. Biol Psychiatry (2008) 1.07
Ethanol action on dopaminergic neurons in the ventral tegmental area: interaction with intrinsic ion channels and neurotransmitter inputs. Int Rev Neurobiol (2010) 1.05
Hypocretin/orexin in arousal and stress. Brain Res (2009) 1.03
Differential effects of acute and chronic ethanol exposure on orexin expression in the perifornical lateral hypothalamus. Alcohol Clin Exp Res (2010) 1.01
Orexin/hypocretin modulation of the basal forebrain cholinergic system: Role in attention. Brain Res (2009) 0.98
Complementary roles of orexin and melanin-concentrating hormone in feeding behavior. Int J Endocrinol (2013) 0.97
The orexins/hypocretins and schizophrenia. Schizophr Bull (2007) 0.93
Hypocretin/orexin regulation of dopamine signaling: implications for reward and reinforcement mechanisms. Front Behav Neurosci (2012) 0.93
Orexin/hypocretin role in reward: implications for opioid and other addictions. Br J Pharmacol (2014) 0.92
Local hypocretin-1 modulates terminal dopamine concentration in the nucleus accumbens shell. Front Behav Neurosci (2012) 0.92
Hypocretin-1 dose-dependently modulates maternal behaviour in mice. J Neuroendocrinol (2006) 0.91
Tobacco dependence, the insular cortex and the hypocretin connection. Pharmacol Biochem Behav (2010) 0.89
Hypocretin mechanisms in nicotine addiction: evidence and speculation. Psychopharmacology (Berl) (2009) 0.87
Hypocretin (orexin) neuromodulation of stress and reward pathways. Curr Opin Neurobiol (2014) 0.87
The dual orexin/hypocretin receptor antagonist, almorexant, in the ventral tegmental area attenuates ethanol self-administration. PLoS One (2012) 0.87
Lateral hypothalamic orexin/hypocretin neurons that project to ventral tegmental area are differentially activated with morphine preference. J Neurosci (2012) 0.86
To ingest or rest? Specialized roles of lateral hypothalamic area neurons in coordinating energy balance. Front Syst Neurosci (2015) 0.85
Role of lateral hypothalamus in two aspects of attention in associative learning. Eur J Neurosci (2014) 0.84
Antagonism of orexin 1 receptors eliminates motor hyperactivity and improves homing response acquisition in juvenile rats exposed to alcohol during early postnatal period. Behav Brain Res (2011) 0.84
Acute pain and a motivational pathway in adult rats: influence of early life pain experience. PLoS One (2012) 0.83
Contribution of transcranial oscillatory stimulation to research on neural networks: an emphasis on hippocampo-neocortical rhythms. Front Hum Neurosci (2013) 0.82
Mechanisms underlying obesity resistance associated with high spontaneous physical activity. Neuroscience (2013) 0.82
Neuropharmacology of Sleep and Wakefulness. Sleep Med Clin (2010) 0.81
Hypocretin receptor 1 blockade preferentially reduces high effort responding for cocaine without promoting sleep. Behav Brain Res (2015) 0.80
Diversity of Dopaminergic Neural Circuits in Response to Drug Exposure. Neuropsychopharmacology (2016) 0.79
Orexin-1 receptor antagonism does not reduce the rewarding potency of cocaine in Swiss-Webster mice. Brain Res (2011) 0.79
Intravenous prenatal nicotine exposure increases orexin expression in the lateral hypothalamus and orexin innervation of the ventral tegmental area in adult male rats. Drug Alcohol Depend (2013) 0.79
Hypocretin (orexin) regulates glutamate input to fast-spiking interneurons in layer V of the Fr2 region of the murine prefrontal cortex. Cereb Cortex (2013) 0.78
Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons. Mol Metab (2015) 0.77
Hypocretin/orexin involvement in reward and reinforcement. Vitam Horm (2012) 0.77
Neuropharmacology of Sleep and Wakefulness: 2012 Update. Sleep Med Clin (2012) 0.77
Orexinergic input to dopaminergic neurons of the human ventral tegmental area. PLoS One (2013) 0.77
Orexin receptors within the nucleus accumbens shell mediate the stress but not drug priming-induced reinstatement of morphine conditioned place preference. Front Behav Neurosci (2013) 0.77
Treatment-like steady-state methadone in rats interferes with incubation of cocaine sensitization and associated alterations in gene expression. Eur Neuropsychopharmacol (2011) 0.76
Hypocretin1/orexinA-immunoreactive axons form few synaptic contacts on rat ventral tegmental area neurons that project to the medial prefrontal cortex. BMC Neurosci (2014) 0.76
Cellular activation of hypothalamic hypocretin/orexin neurons facilitates short-term spatial memory in mice. Neurobiol Learn Mem (2016) 0.75
Basal Forebrain Cholinergic System and Orexin Neurons: Effects on Attention. Front Behav Neurosci (2017) 0.75
Advances in studying phasic dopamine signaling in brain reward mechanisms. Front Biosci (Elite Ed) (2013) 0.75
Overlapping distributions of orexin/hypocretin- and dopamine-beta-hydroxylase immunoreactive fibers in rat brain regions mediating arousal, motivation, and stress. J Comp Neurol (2003) 1.98
Organization of hypocretin/orexin efferents to locus coeruleus and basal forebrain arousal-related structures. J Comp Neurol (2005) 1.17
Cognition-enhancing doses of methylphenidate preferentially increase prefrontal cortex neuronal responsiveness. Biol Psychiatry (2008) 1.15
Hypocretin /orexin preferentially activates caudomedial ventral tegmental area dopamine neurons. Eur J Neurosci (2008) 1.13
Circadian-dependent and circadian-independent behavioral actions of hypocretin/orexin. Brain Res (2002) 1.07
Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with attention-deficit/hyperactivity disorder: evidence from 2 birth cohorts. Arch Gen Psychiatry (2006) 1.02
Wake-promoting actions of dopamine D1 and D2 receptor stimulation. J Pharmacol Exp Ther (2003) 0.97
Psychostimulants act within the prefrontal cortex to improve cognitive function. Biol Psychiatry (2011) 0.96
Low-dose methylphenidate actions on tonic and phasic locus coeruleus discharge. J Pharmacol Exp Ther (2006) 0.94
Organization of noradrenergic efferents to arousal-related basal forebrain structures. J Comp Neurol (2006) 0.94
Stress-induced impairment of a working memory task: role of spiking rate and spiking history predicted discharge. PLoS Comput Biol (2012) 0.89
A selective dopamine reuptake inhibitor improves prefrontal cortex-dependent cognitive function: potential relevance to attention deficit hyperactivity disorder. Neuropharmacology (2012) 0.87
Corticotropin-releasing factor acting at the locus coeruleus disrupts thalamic and cortical sensory-evoked responses. Neuropsychopharmacology (2012) 0.86
Experimental strategies for investigating psychostimulant drug actions and prefrontal cortical function in ADHD and related attention disorders. Anat Rec (Hoboken) (2011) 0.82
AMPA receptor stimulation within the central nucleus of the amygdala elicits a differential activation of central dopaminergic systems. Neuropsychopharmacology (2003) 0.81
Coping behavior causes asymmetric changes in neuronal activation in the prefrontal cortex and amygdala. Synapse (2009) 0.80
Wake-promoting actions of noradrenergic α1 - and β-receptors within the lateral hypothalamic area. Eur J Neurosci (2012) 0.79
Both corticotropin-releasing factor and apomorphine reduce prepulse inhibition following repeated central infusion of corticotropin-releasing factor. Pharmacol Biochem Behav (2006) 0.79
Diurnal levels of Fos immunoreactivity are elevated within hypocretin neurons in lactating mice. Peptides (2004) 0.78
Neurocircuitry underlying the preferential sensitivity of prefrontal catecholamines to low-dose psychostimulants. Neuropsychopharmacology (2013) 0.77
Amphetamine acts within the lateral hypothalamic area to elicit affectively neutral arousal and reinstate drug-seeking. Int J Neuropsychopharmacol (2013) 0.76
4-phenoxypiperidines: potent, conformationally restricted, non-imidazole histamine H3 antagonists. J Med Chem (2005) 0.75