Detection of Pseudomonas aeruginosa producing metallo-beta-lactamases in a large centralized laboratory.

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Published in J Clin Microbiol on July 01, 2005

Authors

Johann D D Pitout1, Daniel B Gregson, Laurent Poirel, Jo-Ann McClure, Phillip Le, Deirdre L Church

Author Affiliations

1: Division of Microbiology, Calgary Laboratory Services, #9, 3535 Research Road NW, Calgary, Alberta, Canada T2L 2K8. johann.pitout@cls.ab.ca.

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Superbugs in the coming new decade; multidrug resistance and prospects for treatment of Staphylococcus aureus, Enterococcus spp. and Pseudomonas aeruginosa in 2010. Curr Opin Microbiol (2007) 1.50

Spectrophotometry-based detection of carbapenemase producers among Enterobacteriaceae. Diagn Microbiol Infect Dis (2012) 1.50

Extended-spectrum beta-lactamases of the CTX-M type now in Switzerland. Antimicrob Agents Chemother (2007) 1.49