Myosins: tails (and heads) of functional diversity.

PubWeight™: 2.55‹?› | Rank: Top 2%

🔗 View Article (PMID 16024512)

Published in Physiology (Bethesda) on August 01, 2005

Authors

Mira Krendel1, Mark S Mooseker

Author Affiliations

1: Department of Molecular Biology, Yale University, New Haven, CN, USA. mira.krendel@yale.edu

Articles citing this

Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol (2009) 7.77

The yeast actin cytoskeleton: from cellular function to biochemical mechanism. Microbiol Mol Biol Rev (2006) 2.55

Drawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 species. Genome Biol (2007) 2.53

Walking to work: roles for class V myosins as cargo transporters. Nat Rev Mol Cell Biol (2011) 1.93

Actin dynamics is essential for myosin-based transport of membrane organelles. Curr Biol (2008) 1.80

Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration. J Exp Med (2008) 1.76

Filopodia act as phagocytic tentacles and pull with discrete steps and a load-dependent velocity. Proc Natl Acad Sci U S A (2007) 1.72

A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions. PLoS One (2007) 1.72

Myosin-IXA regulates collective epithelial cell migration by targeting RhoGAP activity to cell-cell junctions. Curr Biol (2012) 1.70

Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles. Proc Natl Acad Sci U S A (2006) 1.68

A novel role of myosin VI in human prostate cancer. Am J Pathol (2006) 1.59

Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells. J Cell Sci (2009) 1.55

Retroviral proteins that interact with the host cell cytoskeleton. Curr Opin Immunol (2007) 1.46

Herpesvirus interactions with the host cytoskeleton. J Virol (2008) 1.43

Multiple roles of the cytoskeleton in autophagy. Biol Rev Camb Philos Soc (2009) 1.43

TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. J Mol Biol (2008) 1.32

MyosinV controls PTEN function and neuronal cell size. Nat Cell Biol (2009) 1.32

Motor number controls cargo switching at actin-microtubule intersections in vitro. Curr Biol (2010) 1.30

Disruption of Myosin 1e promotes podocyte injury. J Am Soc Nephrol (2008) 1.27

The myosin superfamily at a glance. J Cell Sci (2012) 1.23

Regulation of platelet myosin light chain (MYL9) by RUNX1: implications for thrombocytopenia and platelet dysfunction in RUNX1 haplodeficiency. Blood (2010) 1.17

Myo1c regulates lipid raft recycling to control cell spreading, migration and Salmonella invasion. J Cell Sci (2012) 1.16

Mutations in the first MyTH4 domain of MYO15A are a common cause of DFNB3 hearing loss. Laryngoscope (2009) 1.16

An extended proteome map of the lysosomal membrane reveals novel potential transporters. Mol Cell Proteomics (2013) 1.13

Myosin motor function: the ins and outs of actin-based membrane protrusions. Cell Mol Life Sci (2010) 1.12

Shaking the myosin family tree: biochemical kinetics defines four types of myosin motor. Semin Cell Dev Biol (2011) 1.08

Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC. Oncogene (2009) 1.07

Conditional ablation of nonmuscle myosin II-B delineates heart defects in adult mice. Circ Res (2009) 1.03

Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins. Proc Natl Acad Sci U S A (2011) 1.01

The class V myosin motor, myosin 5c, localizes to mature secretory vesicles and facilitates exocytosis in lacrimal acini. Am J Physiol Cell Physiol (2008) 1.01

Screening for MYO15A gene mutations in autosomal recessive nonsyndromic, GJB2 negative Iranian deaf population. Am J Med Genet A (2012) 0.99

Myosin-1A targets to microvilli using multiple membrane binding motifs in the tail homology 1 (TH1) domain. J Biol Chem (2012) 0.98

The Myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization. Mol Biol Cell (2007) 0.98

Rho, nuclear actin, and actin-binding proteins in the regulation of transcription and gene expression. Small GTPases (2014) 0.98

Reconstructing the phylogeny of 21 completely sequenced arthropod species based on their motor proteins. BMC Genomics (2009) 0.96

Myosin VI small insert isoform maintains exocytosis by tethering secretory granules to the cortical actin. J Cell Biol (2013) 0.96

Molecular motors: directing traffic during RNA localization. Crit Rev Biochem Mol Biol (2011) 0.93

Yeast homologues of lethal giant larvae and type V myosin cooperate in the regulation of Rab-dependent vesicle clustering and polarized exocytosis. Mol Biol Cell (2011) 0.92

Motors and their tethers: the role of secondary binding sites in processive motility. Cell Cycle (2006) 0.92

A myosin V inhibitor based on privileged chemical scaffolds. Angew Chem Int Ed Engl (2010) 0.91

Brush border myosin Ia has tumor suppressor activity in the intestine. Proc Natl Acad Sci U S A (2012) 0.91

Structural insights into functional overlapping and differentiation among myosin V motors. J Biol Chem (2013) 0.90

Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation. Proc Natl Acad Sci U S A (2016) 0.90

The cortical acto-Myosin network: from diffusion barrier to functional gateway in the transport of neurosecretory vesicles to the plasma membrane. Front Endocrinol (Lausanne) (2013) 0.90

Diversity and convergence in the mechanisms establishing L/R asymmetry in metazoa. EMBO Rep (2014) 0.90

The novel proteins Rng8 and Rng9 regulate the myosin-V Myo51 during fission yeast cytokinesis. J Cell Biol (2014) 0.89

A homozygous loss-of-function variant in MYH11 in a case with megacystis-microcolon-intestinal hypoperistalsis syndrome. Eur J Hum Genet (2014) 0.88

Directional spread of alphaherpesviruses in the nervous system. Viruses (2013) 0.88

Whole genome duplication events in plant evolution reconstructed and predicted using myosin motor proteins. BMC Evol Biol (2013) 0.88

Calmodulin regulates dimerization, motility, and lipid binding of Leishmania myosin XXI. Proc Natl Acad Sci U S A (2013) 0.86

Roles for Drosophila melanogaster myosin IB in maintenance of enterocyte brush-border structure and resistance to the bacterial pathogen Pseudomonas entomophila. Mol Biol Cell (2007) 0.86

Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis. Cytoskeleton (Hoboken) (2014) 0.85

Invertebrate and vertebrate class III myosins interact with MORN repeat-containing adaptor proteins. PLoS One (2015) 0.85

Lever-arm mechanics of processive myosins. Biophys J (2011) 0.85

An unconventional myosin required for cell polarization and chemotaxis. Proc Natl Acad Sci U S A (2010) 0.84

Translocation of transfected GLUT2 to the apical membrane in rat intestinal IEC-6 cells. Dig Dis Sci (2011) 0.84

Various Themes of Myosin Regulation. J Mol Biol (2016) 0.83

Structural and functional insights on the Myosin superfamily. Bioinform Biol Insights (2012) 0.83

Identification and Clinical Implications of Novel MYO15A Mutations in a Non-consanguineous Korean Family by Targeted Exome Sequencing. Mol Cells (2015) 0.83

A rare case of chronic myeloid leukemia with secondary chromosomal changes including partial trisomy 17q21 to 17qter and partial monosomy of 16p13.3. Mol Cytogenet (2010) 0.82

A Brucella virulence factor targets macrophages to trigger B-cell proliferation. J Biol Chem (2013) 0.82

Somatic mutation analysis of MYH11 in breast and prostate cancer. BMC Cancer (2008) 0.81

Identification of cytoskeleton-associated proteins essential for lysosomal stability and survival of human cancer cells. PLoS One (2012) 0.81

PATHOLOGIES OF AXONAL TRANSPORT IN NEURODEGENERATIVE DISEASES. Transl Neurosci (2012) 0.81

Cloning, expression, and characterization of a novel molecular motor, Leishmania myosin-XXI. J Biol Chem (2012) 0.81

Dynamic regulation of vascular myosin light chain (MYL9) with injury and aging. PLoS One (2011) 0.81

The protein kinase A-anchoring protein moesin is bound to pigment granules in melanophores. Traffic (2008) 0.81

Molecular basis of dynamic relocalization of Dictyostelium myosin IB. J Biol Chem (2012) 0.81

Genomic Insight into the Host-Endosymbiont Relationship of Endozoicomonas montiporae CL-33(T) with its Coral Host. Front Microbiol (2016) 0.80

Class I myosins have overlapping and specialized functions in left-right asymmetric development in Drosophila. Genetics (2015) 0.80

Myosin VI regulates actin structure specialization through conserved cargo-binding domain sites. PLoS One (2011) 0.80

Plant-Specific Myosin XI, a Molecular Perspective. Front Plant Sci (2012) 0.79

Kinetic Adaptations of Myosins for Their Diverse Cellular Functions. Traffic (2016) 0.79

The SH3 domain of a M7 interacts with its C-terminal proline-rich region. Protein Sci (2006) 0.79

From damage response to action potentials: early evolution of neural and contractile modules in stem eukaryotes. Philos Trans R Soc Lond B Biol Sci (2016) 0.78

Myosin Id is required for planar cell polarity in ciliated tracheal and ependymal epithelial cells. Cytoskeleton (Hoboken) (2015) 0.78

Kinetic analysis reveals differences in the binding mechanism of calmodulin and calmodulin-like protein to the IQ motifs of myosin-10. Biochemistry (2010) 0.78

Myosins as fundamental components during tumorigenesis: diverse and indispensable. Oncotarget (2016) 0.78

Class I myosin Myo1e regulates TLR4-triggered macrophage spreading, chemokine release, and antigen presentation via MHC class II. Eur J Immunol (2014) 0.77

Molecular motors and apical CFTR traffic in epithelia. Int J Mol Sci (2013) 0.77

Myosinome: a database of myosins from select eukaryotic genomes to facilitate analysis of sequence-structure-function relationships. Bioinform Biol Insights (2012) 0.77

Drak Is Required for Actomyosin Organization During Drosophila Cellularization. G3 (Bethesda) (2016) 0.76

Comparative Proteomic Analysis of Buffalo Oocytes Matured in vitro Using iTRAQ Technique. Sci Rep (2016) 0.76

The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity. PLoS One (2014) 0.76

My oh my(osin): Insights into how auditory hair cells count, measure, and shape. J Cell Biol (2016) 0.75

Comparative analysis of DNA methylome and transcriptome of skeletal muscle in lean-, obese-, and mini-type pigs. Sci Rep (2017) 0.75

Myosin light-chain kinase is necessary for membrane homeostasis in cochlear inner hair cells. PLoS One (2012) 0.75

Transport of germ cells across the seminiferous epithelium during spermatogenesis-the involvement of both actin- and microtubule-based cytoskeletons. Tissue Barriers (2016) 0.75

Trafficking of excitatory amino acid transporter 2-laden vesicles in cultured astrocytes: a comparison between approximate and exact determination of trajectory angles. Amino Acids (2014) 0.75

Recent advances in muscle research. Anat Rec (Hoboken) (2014) 0.75

Testis-Specific GTPase (TSG): An oligomeric protein. BMC Genomics (2016) 0.75

Cytoskeleton Molecular Motors: Structures and Their Functions in Neuron. Int J Biol Sci (2016) 0.75

Chemomechanical regulation of myosin Ic cross-bridges: Deducing the elastic properties of an ensemble from single-molecule mechanisms. PLoS Comput Biol (2017) 0.75

Downregulation of myosin VI reduced cell growth and increased apoptosis in human colorectal cancer. Acta Biochim Biophys Sin (Shanghai) (2016) 0.75

Measuring the Kinetic and Mechanical Properties of Non-processive Myosins Using Optical Tweezers. Methods Mol Biol (2017) 0.75

Myosin Va plays essential roles in maintaining normal mitosis, enhancing tumor cell motility and viability. Oncotarget (2017) 0.75

A small molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle. J Biol Chem (2017) 0.75

Articles by these authors

Myosin-1a is critical for normal brush border structure and composition. Mol Biol Cell (2005) 2.44

A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis. J Cell Biol (2005) 1.90

Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis. FEBS Lett (2007) 1.64

The Abl-related gene (Arg) requires its F-actin-microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesion. J Cell Biol (2004) 1.51

A role for myosin-1A in the localization of a brush border disaccharidase. J Cell Biol (2004) 1.49

Disruption of Myosin 1e promotes podocyte injury. J Am Soc Nephrol (2008) 1.27

Myosin at work: motor adaptations for a variety of cellular functions. Biochim Biophys Acta (2006) 1.25

Modulation of cell adhesion and motility in the immune system by Myo1f. Science (2006) 1.22

Myosin-IXb is a single-headed and processive motor. J Biol Chem (2002) 1.19

Myosin-Va binds to and mechanochemically couples microtubules to actin filaments. Mol Biol Cell (2003) 1.11

The tail domain of myosin Va modulates actin binding to one head. J Biol Chem (2006) 0.99

Myosin VI is required for maintenance of brush border structure, composition, and membrane trafficking functions in the intestinal epithelial cell. Cytoskeleton (Hoboken) (2012) 0.97

Native Myosin-IXb is a plus-, not a minus-end-directed motor. Nat Cell Biol (2003) 0.95

Brush border myosin Ia has tumor suppressor activity in the intestine. Proc Natl Acad Sci U S A (2012) 0.91

Drosophila myosin V is required for larval development and spermatid individualization. Dev Biol (2005) 0.91

Myo2p, a class V myosin in budding yeast, associates with a large ribonucleic acid-protein complex that contains mRNAs and subunits of the RNA-processing body. RNA (2008) 0.91

Myosin-V motility: these levers were made for walking. Trends Cell Biol (2003) 0.89

Altered renal proximal tubular endocytosis and histology in mice lacking myosin-VI. Cytoskeleton (Hoboken) (2010) 0.89

Cell polarity protein Spa2P associates with proteins involved in actin function in Saccharomyces cerevisiae. Mol Biol Cell (2005) 0.88

Myosin Ia is required for CFTR brush border membrane trafficking and ion transport in the mouse small intestine. Traffic (2012) 0.87

Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow-derived dendritic cells. Cell Motil Cytoskeleton (2007) 0.86

Roles for Drosophila melanogaster myosin IB in maintenance of enterocyte brush-border structure and resistance to the bacterial pathogen Pseudomonas entomophila. Mol Biol Cell (2007) 0.86

A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulation. Mol Biol Cell (2012) 0.85

Brush border myosin Ia inactivation in gastric but not endometrial tumors. Int J Cancer (2012) 0.82

Plus-end directed myosins accelerate actin filament sliding by single-headed myosin VI. Cytoskeleton (Hoboken) (2012) 0.77