Published in Int J Mol Sci on May 03, 2013
Identification of intestinal ion transport defects in microvillus inclusion disease. Am J Physiol Gastrointest Liver Physiol (2016) 0.75
Nucleoside-Diphosphate-Kinase of P. gingivalis is Secreted from Epithelial Cells In the Absence of a Leader Sequence Through a Pannexin-1 Interactome. Sci Rep (2016) 0.75
The molecular motor toolbox for intracellular transport. Cell (2003) 9.97
Cystic fibrosis. N Engl J Med (2005) 8.09
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell (1991) 3.75
The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature (2006) 3.66
Unconventional myosins in cell movement, membrane traffic, and signal transduction. Science (1998) 3.53
Role of CFTR in airway disease. Physiol Rev (1999) 3.33
New insights into cystic fibrosis: molecular switches that regulate CFTR. Nat Rev Mol Cell Biol (2006) 2.83
The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells. J Biol Chem (1993) 2.65
Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis. EMBO J (2001) 2.57
Myosins: tails (and heads) of functional diversity. Physiology (Bethesda) (2005) 2.55
Myosin-1a is critical for normal brush border structure and composition. Mol Biol Cell (2005) 2.44
MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity. Nat Genet (2008) 2.24
Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator. Mol Biol Cell (2004) 2.21
Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. Mol Biol Cell (2005) 2.13
Cytoplasmic dynein/dynactin mediates the assembly of aggresomes. Cell Motil Cytoskeleton (2002) 2.11
Membrane trafficking of the cystic fibrosis gene product, cystic fibrosis transmembrane conductance regulator, tagged with green fluorescent protein in madin-darby canine kidney cells. J Biol Chem (1998) 1.77
Microvillus inclusion disease: an inherited defect of brush-border assembly and differentiation. N Engl J Med (1989) 1.77
Innate immune response in CF airway epithelia: hyperinflammatory? Am J Physiol Cell Physiol (2006) 1.69
The polyglutamine neurodegenerative protein ataxin 3 regulates aggresome formation. Proc Natl Acad Sci U S A (2005) 1.60
Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells. J Biol Chem (2007) 1.56
Exocytosis is not involved in activation of Cl- secretion via CFTR in Calu-3 airway epithelial cells. Am J Physiol (1998) 1.54
A role for myosin-1A in the localization of a brush border disaccharidase. J Cell Biol (2004) 1.49
Expression of the cystic fibrosis gene in human development. Development (1991) 1.45
Multiple unconventional myosin domains of the intestinal brush border cytoskeleton. J Cell Sci (1994) 1.43
Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosis. Gastroenterology (2000) 1.43
Rab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells. Mol Biol Cell (2009) 1.41
Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator. J Biol Chem (2004) 1.40
Physiological relevance of cell-specific distribution patterns of CFTR, NKCC1, NBCe1, and NHE3 along the crypt-villus axis in the intestine. Am J Physiol Gastrointest Liver Physiol (2010) 1.38
Endocytic trafficking of CFTR in health and disease. J Cyst Fibros (2006) 1.36
Defective CFTR apical endocytosis and enterocyte brush border in myosin VI-deficient mice. Traffic (2007) 1.31
CFTR pharmacology and its role in intestinal fluid secretion. Curr Opin Pharmacol (2003) 1.25
Role of microtubules in transferrin receptor transport from the cell surface to endosomes and the Golgi complex. J Biol Chem (1993) 1.23
Cellular localization of the cystic fibrosis transmembrane conductance regulator in mouse intestinal tract. Histochem Cell Biol (2000) 1.22
Loss-of-function of MYO5B is the main cause of microvillus inclusion disease: 15 novel mutations and a CaCo-2 RNAi cell model. Hum Mutat (2010) 1.20
Cystic fibrosis transmembrane conductance regulator intracellular processing, trafficking, and opportunities for mutation-specific treatment. Chest (2011) 1.16
Apical recruitment of CFTR in T-84 cells is dependent on cAMP and microtubules but not Ca2+ or microfilaments. J Cell Sci (1996) 1.16
Vertebrate myosin VIIb is a high duty ratio motor adapted for generating and maintaining tension. J Biol Chem (2005) 1.16
Microvillus inclusion disease: a genetic defect affecting apical membrane protein traffic in intestinal epithelium. Traffic (2000) 1.14
Myosin VI, a new force in clathrin mediated endocytosis. FEBS Lett (2001) 1.14
Heterotrimeric G proteins, vesicle trafficking, and CFTR Cl- channels. Am J Physiol (1994) 1.07
The role of airway epithelium and blood neutrophils in the inflammatory response in cystic fibrosis. J Cyst Fibros (2005) 1.05
Activation of the cystic fibrosis transmembrane conductance regulator by cGMP in the human colonic cancer cell line, Caco-2. J Biol Chem (1994) 1.02
Primaquine blocks transport by inhibiting the formation of functional transport vesicles. Studies in a cell-free assay of protein transport through the Golgi apparatus. J Biol Chem (1991) 1.02
Traffic pattern of cystic fibrosis transmembrane regulator through the early exocytic pathway. Traffic (2000) 1.02
cAMP-independent regulation of CFTR by the actin cytoskeleton. Am J Physiol (1995) 1.00
Mechanisms of CFTR regulation by syntaxin 1A and PKA. J Cell Sci (2002) 1.00
Subcellular distribution of CFTR in rat intestine supports a physiologic role for CFTR regulation by vesicle traffic. Histochem Cell Biol (2000) 0.96
cAMP-dependent exocytosis and vesicle traffic regulate CFTR and fluid transport in rat jejunum in vivo. Am J Physiol Cell Physiol (2003) 0.94
Polarization-dependent apical membrane CFTR targeting underlies cAMP-stimulated Cl- secretion in epithelial cells. Am J Physiol (1994) 0.92
The cystic fibrosis transmembrane conductance regulator's expanding SNARE interactome. Traffic (2011) 0.90
Microtubule disruption inhibits AVT-stimulated Cl- secretion but not Na+ reabsorption in A6 cells. Am J Physiol (1998) 0.90
Selective stimulation of epithelial cells in colonic crypts: relation to active chloride secretion. Am J Physiol (1995) 0.87
The relationship between cAMP, Ca(2)+, and transport of CFTR to the plasma membrane. J Gen Physiol (2001) 0.87
Syntaxin 3 is necessary for cAMP- and cGMP-regulated exocytosis of CFTR: implications for enterotoxigenic diarrhea. Am J Physiol Cell Physiol (2010) 0.87
Myosin Ia is required for CFTR brush border membrane trafficking and ion transport in the mouse small intestine. Traffic (2012) 0.87
Tissue-specific control of CFTR endocytosis by Dab2: Cargo recruitment as a therapeutic target. Commun Integr Biol (2012) 0.86
Actin-dependent activation of ion conductances in bronchial epithelial cells. Pflugers Arch (1995) 0.84
Prostaglandin- and theophylline-induced C1 secretion in rat distal colon is inhibited by microtubule inhibitors. Dig Dis Sci (1992) 0.82
X-ray microanalysis of cell elements in normal and cystic fibrosis jejunum: evidence for chloride secretion in villi. Gastroenterology (1996) 0.80
Mechanisms of bicarbonate secretion: lessons from the airways. Cold Spring Harb Perspect Med (2012) 0.79
Microvillus inclusion disease as a cause of severe protracted diarrhea in infants. J Med Assoc Thai (2001) 0.76
Lubiprostone targets prostanoid signaling and promotes ion transporter trafficking, mucus exocytosis, and contractility. Dig Dis Sci (2012) 1.61
Physiological relevance of cell-specific distribution patterns of CFTR, NKCC1, NBCe1, and NHE3 along the crypt-villus axis in the intestine. Am J Physiol Gastrointest Liver Physiol (2010) 1.38
Heterogeneity in mouse spasmolytic polypeptide-expressing metaplasia lineages identifies markers of metaplastic progression. Gut (2012) 1.13
Myosin Ia is required for CFTR brush border membrane trafficking and ion transport in the mouse small intestine. Traffic (2012) 0.87
Regulated traffic of anion transporters in mammalian Brunner's glands: a role for water and fluid transport. Am J Physiol Gastrointest Liver Physiol (2013) 0.85
Cell-specific effects of luminal acid, bicarbonate, cAMP, and carbachol on transporter trafficking in the intestine. Am J Physiol Gastrointest Liver Physiol (2012) 0.81
Characterization of CFTR High Expresser cells in the intestine. Am J Physiol Gastrointest Liver Physiol (2013) 0.81
Functional vacuolar ATPase (V-ATPase) proton pumps traffic to the enterocyte brush border membrane and require CFTR. Am J Physiol Cell Physiol (2013) 0.76