Published in Mol Biol Cell on May 09, 2012
RhoGTPases, actomyosin signaling and regulation of the epithelial Apical Junctional Complex. Semin Cell Dev Biol (2014) 0.95
IBD candidate genes and intestinal barrier regulation. Inflamm Bowel Dis (2014) 0.92
Epithelial junctions and Rho family GTPases: the zonular signalosome. Small GTPases (2014) 0.91
Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms. Tissue Barriers (2013) 0.90
Myosins in cell junctions. Bioarchitecture (2012) 0.89
Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes. Am J Physiol Renal Physiol (2013) 0.86
Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis. Cytoskeleton (Hoboken) (2014) 0.85
Rho GAPs and GEFs: controling switches in endothelial cell adhesion. Cell Adh Migr (2014) 0.82
The intestinal epithelial barrier: a therapeutic target? Nat Rev Gastroenterol Hepatol (2016) 0.78
Association of MYO9B gene polymorphisms with inflammatory bowel disease in Chinese Han population. World J Gastroenterol (2014) 0.77
The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity. PLoS One (2014) 0.76
MicroRNA expression profiling of human blood monocyte subsets highlights functional differences. Immunology (2015) 0.75
Arhgap17, a RhoGTPase activating protein, regulates mucosal and epithelial barrier function in the mouse colon. Sci Rep (2016) 0.75
Celiac Disease: Role of the Epithelial Barrier. Cell Mol Gastroenterol Hepatol (2017) 0.75
Rho GTPases and the actin cytoskeleton. Science (1998) 28.19
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase) Science (1996) 15.88
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem (1996) 10.51
Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol (2009) 9.87
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science (2005) 8.97
Rocks: multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol (2003) 8.68
Lamellipodial actin mechanically links myosin activity with adhesion-site formation. Cell (2007) 4.59
Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms. J Immunol (2003) 4.00
Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow. Biophys J (2006) 3.83
Visualization of melanosome dynamics within wild-type and dilute melanocytes suggests a paradigm for myosin V function In vivo. J Cell Biol (1998) 3.21
Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation. Am J Physiol (1997) 3.07
Characterization of the enterocyte-like brush border cytoskeleton of the C2BBe clones of the human intestinal cell line, Caco-2. J Cell Sci (1992) 2.80
A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest (2004) 2.75
Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect. Nat Genet (2005) 2.71
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. J Cell Sci (2006) 2.59
Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6. Nat Cell Biol (2010) 2.58
Regulation of non-muscle myosin assembly by calmodulin-dependent light chain kinase. Nature (1980) 2.53
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nat Cell Biol (2010) 2.51
Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane. Mol Biol Cell (2005) 2.46
Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation. Gut (2003) 2.37
Epithelial properties of human colonic carcinoma cell line Caco-2: electrical parameters. Am J Physiol (1984) 2.01
Activation of beta1 integrin signaling stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protrusive activities at invadopodia. J Biol Chem (1998) 1.87
Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria. J Immunol (2005) 1.82
Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia. Gastroenterology (2001) 1.79
Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types. Proc Natl Acad Sci U S A (1994) 1.77
Myosin-IXA regulates collective epithelial cell migration by targeting RhoGAP activity to cell-cell junctions. Curr Biol (2012) 1.70
Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis. FEBS Lett (2007) 1.64
Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase. J Biol Chem (1996) 1.55
Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions. Mol Biol Cell (2007) 1.50
Endotoxin inhibits intestinal epithelial restitution through activation of Rho-GTPase and increased focal adhesions. J Biol Chem (2004) 1.49
A role for myosin-1A in the localization of a brush border disaccharidase. J Cell Biol (2004) 1.49
The tail of a yeast class V myosin, myo2p, functions as a localization domain. Mol Biol Cell (1999) 1.48
Rho proteins play a critical role in cell migration during the early phase of mucosal restitution. J Clin Invest (1997) 1.40
PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase. Am J Physiol (1999) 1.33
Genetic variation in myosin IXB is associated with ulcerative colitis. Gastroenterology (2006) 1.29
Human myosin-IXb is a mechanochemically active motor and a GAP for rho. J Cell Sci (1998) 1.27
Myosin at work: motor adaptations for a variety of cellular functions. Biochim Biophys Acta (2006) 1.25
Myosin IXb is a single-headed minus-end-directed processive motor. Nat Cell Biol (2002) 1.23
Myosin-IXb is a single-headed and processive motor. J Biol Chem (2002) 1.19
Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus. Mol Biol Cell (2009) 1.10
The rat myosin myr 5 is a GTPase-activating protein for Rho in vivo: essential role of arginine 1695. Mol Biol Cell (1997) 1.07
Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motility. Proc Natl Acad Sci U S A (2010) 1.05
p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration. J Biol Chem (2008) 1.03
Rho and Rho-kinase (ROCK) signaling in adherens and gap junction assembly in corneal epithelium. Invest Ophthalmol Vis Sci (2002) 1.02
Native Myosin-IXb is a plus-, not a minus-end-directed motor. Nat Cell Biol (2003) 0.95
p190 RhoGAP, the major RasGAP-associated protein, binds GTP directly. Mol Cell Biol (1994) 0.93
Head of myosin IX binds calmodulin and moves processively toward the plus-end of actin filaments. J Biol Chem (2010) 0.91
Myr 7 is a novel myosin IX-RhoGAP expressed in rat brain. J Cell Sci (1998) 0.89
MYO9B polymorphisms in patients with inflammatory bowel disease. Gut (2007) 0.87
Endocytosis and recycling of tight junction proteins in inflammation. J Biomed Biotechnol (2010) 0.86
RhoA GTPase and F-actin dynamically regulate the permeability of Cx43-made channels in rat cardiac myocytes. J Biol Chem (2008) 0.86
Association between genetic variants in myosin IXB and Crohn's disease. Inflamm Bowel Dis (2009) 0.86
Myosins: tails (and heads) of functional diversity. Physiology (Bethesda) (2005) 2.55
Myosin-1a is critical for normal brush border structure and composition. Mol Biol Cell (2005) 2.44
A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis. J Cell Biol (2005) 1.90
Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis. FEBS Lett (2007) 1.64
The Abl-related gene (Arg) requires its F-actin-microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesion. J Cell Biol (2004) 1.51
A role for myosin-1A in the localization of a brush border disaccharidase. J Cell Biol (2004) 1.49
Disruption of Myosin 1e promotes podocyte injury. J Am Soc Nephrol (2008) 1.27
Myosin at work: motor adaptations for a variety of cellular functions. Biochim Biophys Acta (2006) 1.25
Modulation of cell adhesion and motility in the immune system by Myo1f. Science (2006) 1.22
Myosin-IXb is a single-headed and processive motor. J Biol Chem (2002) 1.19
Myosin-Va binds to and mechanochemically couples microtubules to actin filaments. Mol Biol Cell (2003) 1.11
The tail domain of myosin Va modulates actin binding to one head. J Biol Chem (2006) 0.99
Myosin VI is required for maintenance of brush border structure, composition, and membrane trafficking functions in the intestinal epithelial cell. Cytoskeleton (Hoboken) (2012) 0.97
Native Myosin-IXb is a plus-, not a minus-end-directed motor. Nat Cell Biol (2003) 0.95
Brush border myosin Ia has tumor suppressor activity in the intestine. Proc Natl Acad Sci U S A (2012) 0.91
Drosophila myosin V is required for larval development and spermatid individualization. Dev Biol (2005) 0.91
Myosin-V motility: these levers were made for walking. Trends Cell Biol (2003) 0.89
Altered renal proximal tubular endocytosis and histology in mice lacking myosin-VI. Cytoskeleton (Hoboken) (2010) 0.89
Cell polarity protein Spa2P associates with proteins involved in actin function in Saccharomyces cerevisiae. Mol Biol Cell (2005) 0.88
Myosin Ia is required for CFTR brush border membrane trafficking and ion transport in the mouse small intestine. Traffic (2012) 0.87
Roles for Drosophila melanogaster myosin IB in maintenance of enterocyte brush-border structure and resistance to the bacterial pathogen Pseudomonas entomophila. Mol Biol Cell (2007) 0.86
Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow-derived dendritic cells. Cell Motil Cytoskeleton (2007) 0.86
Brush border myosin Ia inactivation in gastric but not endometrial tumors. Int J Cancer (2012) 0.82
Plus-end directed myosins accelerate actin filament sliding by single-headed myosin VI. Cytoskeleton (Hoboken) (2012) 0.77