Published in Proteomics on August 01, 2005
Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution. Mol Cell Proteomics (2007) 6.96
Multiplexed protein measurement: technologies and applications of protein and antibody arrays. Nat Rev Drug Discov (2006) 3.83
Human body fluid proteome analysis. Proteomics (2006) 2.39
Advances and challenges in liquid chromatography-mass spectrometry-based proteomics profiling for clinical applications. Mol Cell Proteomics (2006) 2.14
Anti-NMDA receptor encephalitis antibody binding is dependent on amino acid identity of a small region within the GluN1 amino terminal domain. J Neurosci (2012) 1.82
Metrics for the Human Proteome Project 2013-2014 and strategies for finding missing proteins. J Proteome Res (2013) 1.76
Folding-based electrochemical biosensors: the case for responsive nucleic acid architectures. Acc Chem Res (2010) 1.75
Candidate serological biomarkers for cancer identified from the secretomes of 23 cancer cell lines and the human protein atlas. Mol Cell Proteomics (2010) 1.52
Advancing the sensitivity of selected reaction monitoring-based targeted quantitative proteomics. Proteomics (2012) 1.30
Switch-based biosensors: a new approach towards real-time, in vivo molecular detection. Trends Biotechnol (2010) 1.27
Comparison of extensive protein fractionation and repetitive LC-MS/MS analyses on depth of analysis for complex proteomes. J Proteome Res (2010) 1.25
A database of reaction monitoring mass spectrometry assays for elucidating therapeutic response in cancer. Proteomics Clin Appl (2011) 1.25
Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discovery. J Proteome Res (2009) 1.18
Mass spectrometric and computational analysis of cytokine-induced alterations in the astrocyte secretome. Proteomics (2009) 1.17
Systematic discovery of ectopic pregnancy serum biomarkers using 3-D protein profiling coupled with label-free quantitation. J Proteome Res (2011) 1.14
Quantitative mass spectrometry-based proteomics reveals the dynamic range of primary mouse astrocyte protein secretion. J Proteome Res (2010) 1.11
The host targeting motif in exported Plasmodium proteins is cleaved in the parasite endoplasmic reticulum. Mol Biochem Parasitol (2010) 1.08
Enhancing identifications of lipid-embedded proteins by mass spectrometry for improved mapping of endothelial plasma membranes in vivo. Mol Cell Proteomics (2009) 0.99
A proteomics platform combining depletion, multi-lectin affinity chromatography (M-LAC), and isoelectric focusing to study the breast cancer proteome. Anal Chem (2011) 0.96
Peroxiredoxin 2: a potential biomarker for early diagnosis of hepatitis B virus related liver fibrosis identified by proteomic analysis of the plasma. BMC Gastroenterol (2010) 0.95
A xenograft mouse model coupled with in-depth plasma proteome analysis facilitates identification of novel serum biomarkers for human ovarian cancer. J Proteome Res (2011) 0.95
Identifying new therapeutic targets via modulation of protein corona formation by engineered nanoparticles. PLoS One (2012) 0.95
Upregulation of plasma C9 protein in gastric cancer patients. Proteomics (2010) 0.89
Aggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity. Cell Microbiol (2007) 0.89
Systematic comparison of fractionation methods for in-depth analysis of plasma proteomes. J Proteome Res (2012) 0.88
Microscale solution isoelectric focusing as an effective strategy enabling containment of hemeoglobin-derived products for high-resolution gel-based analysis of the Plasmodium falciparum proteome. J Proteome Res (2007) 0.87
A systems biology analysis of metastatic melanoma using in-depth three-dimensional protein profiling. Proteomics (2010) 0.85
Data analysis strategy for maximizing high-confidence protein identifications in complex proteomes such as human tumor secretomes and human serum. J Proteome Res (2011) 0.85
Evolving role of bone biomarkers in castration-resistant prostate cancer. Neoplasia (2010) 0.84
Optimization of plasma sample pretreatment for quantitative analysis using iTRAQ labeling and LC-MALDI-TOF/TOF. PLoS One (2014) 0.82
In-depth analysis of a plasma or serum proteome using a 4D protein profiling method. Methods Mol Biol (2011) 0.82
Identification of multiple novel protein biomarkers shed by human serous ovarian tumors into the blood of immunocompromised mice and verified in patient sera. PLoS One (2013) 0.81
Simultaneous Enrichment of Plasma Soluble and Extracellular Vesicular Glycoproteins Using Prolonged Ultracentrifugation-Electrostatic Repulsion-hydrophilic Interaction Chromatography (PUC-ERLIC) Approach. Mol Cell Proteomics (2015) 0.79
Use of composite protein database including search result sequences for mass spectrometric analysis of cell secretome. PLoS One (2015) 0.78
Comparative proteomics and glycoproteomics of plasma proteins in Indian visceral leishmaniasis. Proteome Sci (2014) 0.77
Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science (2013) 6.43
Forced unfolding of proteins within cells. Science (2007) 3.95
Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating. J Cell Sci (2008) 3.86
The proteome of the mouse photoreceptor sensory cilium complex. Mol Cell Proteomics (2007) 3.53
Adeno-associated viruses undergo substantial evolution in primates during natural infections. Proc Natl Acad Sci U S A (2003) 3.31
HUPO Plasma Proteome Project specimen collection and handling: towards the standardization of parameters for plasma proteome samples. Proteomics (2005) 2.71
Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study. Nat Biotechnol (2006) 2.66
The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat Struct Biol (2002) 2.56
A chromatin remodelling complex that loads cohesin onto human chromosomes. Nature (2002) 2.53
Structural and functional effects of hereditary hemolytic anemia-associated point mutations in the alpha spectrin tetramer site. Blood (2008) 2.12
Depletion of multiple high-abundance proteins improves protein profiling capacities of human serum and plasma. Proteomics (2005) 2.02
A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell (2011) 1.86
Epigenetic regulation of condensin-mediated genome organization during the cell cycle and upon DNA damage through histone H3 lysine 56 acetylation. Mol Cell (2012) 1.85
Isolation of human NURF: a regulator of Engrailed gene expression. EMBO J (2003) 1.80
Assessing the feasibility of GS FLX Pyrosequencing for sequencing the Atlantic salmon genome. BMC Genomics (2008) 1.72
Cooperativity in forced unfolding of tandem spectrin repeats. Biophys J (2003) 1.70
Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation. Proc Natl Acad Sci U S A (2003) 1.68
A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes. J Biol Chem (2002) 1.67
Cdc13 OB2 dimerization required for productive Stn1 binding and efficient telomere maintenance. Structure (2012) 1.56
Rational design and characterization of platelet factor 4 antagonists for the study of heparin-induced thrombocytopenia. Blood (2012) 1.50
Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse. Nat Genet (2002) 1.48
Pathway shifts and thermal softening in temperature-coupled forced unfolding of spectrin domains. Biophys J (2003) 1.46
The common hereditary elliptocytosis-associated α-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation. Blood (2013) 1.43
Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanoma. Cell Rep (2013) 1.43
Combining next-generation pyrosequencing with microarray for large scale expression analysis in non-model species. BMC Genomics (2009) 1.37
Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity. Biochem J (2009) 1.32
Landscape of the mitochondrial Hsp90 metabolome in tumours. Nat Commun (2013) 1.29
MYST protein acetyltransferase activity requires active site lysine autoacetylation. EMBO J (2011) 1.29
Endoplasmic reticulum PI(3)P lipid binding targets malaria proteins to the host cell. Cell (2012) 1.26
Erythrocyte detergent-resistant membrane proteins: their characterization and selective uptake during malarial infection. Blood (2003) 1.26
Comparison of extensive protein fractionation and repetitive LC-MS/MS analyses on depth of analysis for complex proteomes. J Proteome Res (2010) 1.25
Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding. Blood (2006) 1.22
Combined use of laser capture microdissection and cDNA microarray analysis identifies locally expressed disease-related genes in focal regions of psoriasis vulgaris skin lesions. J Invest Dermatol (2012) 1.20
Dematin and adducin provide a novel link between the spectrin cytoskeleton and human erythrocyte membrane by directly interacting with glucose transporter-1. J Biol Chem (2008) 1.18
Structure-based identification of a major neutralizing site in an adenovirus hexon. J Virol (2006) 1.17
Mass spectrometric and computational analysis of cytokine-induced alterations in the astrocyte secretome. Proteomics (2009) 1.17
Structural basis for dimerization in DNA recognition by Gal4. Structure (2008) 1.16
Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step. EMBO J (2013) 1.14
Systematic discovery of ectopic pregnancy serum biomarkers using 3-D protein profiling coupled with label-free quantitation. J Proteome Res (2011) 1.14
Gene specific siRNA selector. Bioinformatics (2004) 1.12
Chemistry on a single protein, vascular cell adhesion molecule-1, during forced unfolding. J Biol Chem (2004) 1.11
Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex. Blood (2010) 1.11
Mammalian tropomodulins nucleate actin polymerization via their actin monomer binding and filament pointed end-capping activities. J Biol Chem (2010) 1.11
Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules. J Biol Chem (2001) 1.10
Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition. Cell Cycle (2013) 1.08
The host targeting motif in exported Plasmodium proteins is cleaved in the parasite endoplasmic reticulum. Mol Biochem Parasitol (2010) 1.08
Purification of proteins fused to glutathione S-transferase. Methods Mol Biol (2011) 1.08
Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses. Nat Med (2008) 1.07
Tropomodulin 3 binds to actin monomers. J Biol Chem (2006) 1.07
Western-style diets induce oxidative stress and dysregulate immune responses in the colon in a mouse model of sporadic colon cancer. J Nutr (2009) 1.05
Deciphering the human platelet sheddome. Blood (2010) 1.04
Influence of lateral association on forced unfolding of antiparallel spectrin heterodimers. J Biol Chem (2004) 1.00
Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer. J Proteomics (2013) 0.97
Comprehensive analysis of complex proteomes using microscale solution isoelectrofocusing prior to narrow pH range two-dimensional electrophoresis. Proteomics (2002) 0.97
Higher dimensional (Hi-D) separation strategies dramatically improve the potential for cancer biomarker detection in serum and plasma. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.96
A xenograft mouse model coupled with in-depth plasma proteome analysis facilitates identification of novel serum biomarkers for human ovarian cancer. J Proteome Res (2011) 0.95
A comprehensive model of the spectrin divalent tetramer binding region deduced using homology modeling and chemical cross-linking of a mini-spectrin. J Biol Chem (2010) 0.95
Creating an ontology-based human phenotyping system: The Rockefeller University bleeding history experience. Clin Transl Sci (2009) 0.95
Rapid verification of candidate serological biomarkers using gel-based, label-free multiple reaction monitoring. J Proteome Res (2011) 0.94
Cdc13 N-terminal dimerization, DNA binding, and telomere length regulation. Mol Cell Biol (2010) 0.94
Supervised regularized canonical correlation analysis: integrating histologic and proteomic measurements for predicting biochemical recurrence following prostate surgery. BMC Bioinformatics (2011) 0.93
A common DNA-binding site for SZF1 and the BRCA1-associated zinc finger protein, ZBRK1. Cancer Res (2002) 0.92
N-terminal sequence analysis of proteins and peptides. Curr Protoc Protein Sci (2009) 0.90
Cysteine shotgun-mass spectrometry (CS-MS) reveals dynamic sequence of protein structure changes within mutant and stressed cells. Proc Natl Acad Sci U S A (2011) 0.90
Aggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity. Cell Microbiol (2007) 0.89
Complex proteome prefractionation using microscale solution isoelectrofocusing. Expert Rev Proteomics (2005) 0.89
A structural model of the erythrocyte spectrin heterodimer initiation site determined using homology modeling and chemical cross-linking. J Biol Chem (2007) 0.89
Systematic comparison of fractionation methods for in-depth analysis of plasma proteomes. J Proteome Res (2012) 0.88
Identification of secreted proteins that reflect autophagy dynamics within tumor cells. Autophagy (2015) 0.88
A label-free proteome analysis strategy for identifying quantitative changes in erythrocyte membranes induced by red cell disorders. J Proteomics (2012) 0.88
A fused alpha-beta "mini-spectrin" mimics the intact erythrocyte spectrin head-to-head tetramer. J Biol Chem (2010) 0.88
Identification of alternative products and optimization of 2-nitro-5-thiocyanatobenzoic acid cyanylation and cleavage at cysteine residues. Anal Biochem (2004) 0.87
Molecular diagnosis of ectopic pregnancy. Expert Rev Mol Diagn (2011) 0.86
Plasma biomarker discovery using 3D protein profiling coupled with label-free quantitation. Methods Mol Biol (2011) 0.86
The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain. J Mol Biol (2007) 0.86
Expression and purification of GST fusion proteins. Curr Protoc Protein Sci (2008) 0.86
Initiation and propagation of spectrin heterodimer assembly involves distinct energetic processes. Biochemistry (2007) 0.86
Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target. Mol Cell Proteomics (2013) 0.85
Sense and antisense transcripts of the apolipoprotein E gene in normal and ApoE knockout mice, their expression after spinal cord injury and corresponding human transcripts. Hum Mol Genet (2005) 0.85
A systems biology analysis of metastatic melanoma using in-depth three-dimensional protein profiling. Proteomics (2010) 0.85
Data analysis strategy for maximizing high-confidence protein identifications in complex proteomes such as human tumor secretomes and human serum. J Proteome Res (2011) 0.85
Serial cervicovaginal exposures with replication-deficient SIVsm induce higher dendritic cell (pDC) and CD4+ T-cell infiltrates not associated with prevention but a more severe SIVmac251 infection of rhesus macaques. J Acquir Immune Defic Syndr (2014) 0.85
Probing large conformational rearrangements in wild-type and mutant spectrin using structural mass spectrometry. Proc Natl Acad Sci U S A (2014) 0.84
Enhanced identification of zero-length chemical cross-links using label-free quantitation and high-resolution fragment ion spectra. J Proteome Res (2014) 0.84
PI(3)P-independent and -dependent pathways function together in a vacuolar translocation sequence to target malarial proteins to the host erythrocyte. Mol Biochem Parasitol (2012) 0.84
Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration. Hum Mol Genet (2013) 0.83
Microscale isoelectric focusing in solution: a method for comprehensive and quantitative proteome analysis using 1-D and 2-D DIGE combined with MicroSol IEF prefractionation. Methods Mol Biol (2008) 0.83
CD44 regulates vascular gene expression in a proatherogenic environment. Arterioscler Thromb Vasc Biol (2007) 0.82
In-depth analysis of a plasma or serum proteome using a 4D protein profiling method. Methods Mol Biol (2011) 0.82
The motor protein kinesin-1 links neurofibromin and merlin in a common cellular pathway of neurofibromatosis. J Biol Chem (2002) 0.81
Identification of multiple novel protein biomarkers shed by human serous ovarian tumors into the blood of immunocompromised mice and verified in patient sera. PLoS One (2013) 0.81
In vivo phosphorylation of human erythrocyte spectrin occurs in a sequential manner. Biochemistry (2004) 0.80
Microscale solution IEF combined with 2-D DIGE substantially enhances analysis depth of complex proteomes such as mammalian cell and tissue extracts. Electrophoresis (2008) 0.80
Large-scale purification and crystallization of adenovirus hexon. Methods Mol Med (2007) 0.80