Published in Proteomics on February 01, 2009
Trafficking of immune cells in the central nervous system. J Clin Invest (2010) 2.17
Astrocytes directly influence tumor cell invasion and metastasis in vivo. PLoS One (2013) 1.56
Nitric oxide regulates mitochondrial fatty acid metabolism through reversible protein S-nitrosylation. Sci Signal (2013) 1.45
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation. Fluids Barriers CNS (2012) 1.44
Astrocyte secreted proteins selectively increase hippocampal GABAergic axon length, branching, and synaptogenesis. Mol Cell Neurosci (2009) 1.22
Quantitative mass spectrometry-based proteomics reveals the dynamic range of primary mouse astrocyte protein secretion. J Proteome Res (2010) 1.11
Identification of astrocyte secreted proteins with a combination of shotgun proteomics and bioinformatics. J Proteome Res (2009) 1.00
A role for thrombospondin-1 deficits in astrocyte-mediated spine and synaptic pathology in Down's syndrome. PLoS One (2010) 0.98
GFAP expression as an indicator of disease severity in mouse models of Alexander disease. ASN Neuro (2013) 0.96
The 4-cysteine zinc-finger motif of the RNA polymerase regulator DksA serves as a thiol switch for sensing oxidative and nitrosative stress. Mol Microbiol (2014) 0.96
Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity. J Neuroinflammation (2012) 0.91
Exposure to inflammatory cytokines IL-1β and TNFα induces compromise and death of astrocytes; implications for chronic neuroinflammation. PLoS One (2013) 0.90
Calcineurin and glial signaling: neuroinflammation and beyond. J Neuroinflammation (2014) 0.85
Mass spectrometry-based identification of S-nitrosocysteine in vivo using organic mercury assisted enrichment. Methods (2012) 0.84
Site specific identification of endogenous S-nitrosocysteine proteomes. J Proteomics (2013) 0.84
Proteomic analysis of stromal proteins in different stages of colorectal cancer establishes Tenascin-C as a stromal biomarker for colorectal cancer metastasis. Oncotarget (2016) 0.81
Regulation of brain glutamate metabolism by nitric oxide and S-nitrosylation. Sci Signal (2015) 0.81
TIMP-1 couples RhoK activation to IL-1β-induced astrocyte responses. Neurosci Lett (2015) 0.78
Mass Spectrometry-based Proteomics and Peptidomics for Systems Biology and Biomarker Discovery. Front Biol (Beijing) (2012) 0.77
Therapeutic Targets for Neurodevelopmental Disorders Emerging from Animal Models with Perinatal Immune Activation. Int J Mol Sci (2015) 0.77
Nitric oxide counteracts the hyperoxia-induced proliferation and proinflammatory responses of mouse astrocytes. Free Radic Biol Med (2011) 0.76
The ROP vesicle release factor is required in adult Drosophila glia for normal circadian behavior. Front Cell Neurosci (2015) 0.76
Gypenoside IX Suppresses p38 MAPK/Akt/NFκB Signaling Pathway Activation and Inflammatory Responses in Astrocytes Stimulated by Proinflammatory Mediators. Inflammation (2017) 0.75
Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cells. Cell Commun Signal (2017) 0.75
Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem (2002) 35.30
A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem (2003) 29.58
BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks. Bioinformatics (2005) 24.04
A model for random sampling and estimation of relative protein abundance in shotgun proteomics. Anal Chem (2004) 19.20
Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein. Mol Cell Proteomics (2005) 10.67
Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation. Nat Neurosci (2003) 8.23
Comparison of label-free methods for quantifying human proteins by shotgun proteomics. Mol Cell Proteomics (2005) 8.14
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat Neurosci (2007) 7.77
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis. Cell (2005) 7.41
Astrocytic purinergic signaling coordinates synaptic networks. Science (2005) 6.55
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nat Neurosci (2007) 6.08
CNS synaptogenesis promoted by glia-derived cholesterol. Science (2001) 6.04
Astrocytes, from brain glue to communication elements: the revolution continues. Nat Rev Neurosci (2005) 5.97
GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nat Neurosci (2004) 5.92
Large-scale proteomic analysis of the human spliceosome. Genome Res (2002) 5.75
Astrocyte activation and reactive gliosis. Glia (2005) 5.46
Calcium transients in astrocyte endfeet cause cerebrovascular constrictions. Nature (2004) 4.79
Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci U S A (2004) 4.70
Feature-based prediction of non-classical and leaderless protein secretion. Protein Eng Des Sel (2004) 4.54
CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nat Neurosci (2001) 4.12
Immune function of astrocytes. Glia (2001) 4.05
The proteome of the mouse photoreceptor sensory cilium complex. Mol Cell Proteomics (2007) 3.53
Mimicking cellular sorting improves prediction of subcellular localization. J Mol Biol (2005) 3.21
Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors. Proc Natl Acad Sci U S A (1983) 2.76
The Golgi-associated protein GRASP is required for unconventional protein secretion during development. Cell (2007) 2.73
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides. Nat Med (2004) 2.72
Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination. Nat Neurosci (2004) 2.64
Vimentin is secreted by activated macrophages. Nat Cell Biol (2003) 2.63
Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. J Neurosci (2003) 2.52
Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells. Traffic (2005) 2.34
Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis. Am J Pathol (1997) 1.88
Comparative proteomic and transcriptomic profiling of the fission yeast Schizosaccharomyces pombe. Mol Syst Biol (2007) 1.73
The chemokine receptor CXCR2 controls positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. Cell (2002) 1.73
Systematic analysis of peptide recoveries from in-gel digestions for protein identifications in proteome studies. J Biomol Tech (2000) 1.64
A novel four-dimensional strategy combining protein and peptide separation methods enables detection of low-abundance proteins in human plasma and serum proteomes. Proteomics (2005) 1.62
The mouse secretome: functional classification of the proteins secreted into the extracellular environment. Genome Res (2003) 1.61
Regulated secretion of macrophage migration inhibitory factor is mediated by a non-classical pathway involving an ABC transporter. FEBS Lett (2003) 1.59
Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells. Circ Res (2006) 1.52
Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival. J Biol Chem (2005) 1.36
SledgeHMMER: a web server for batch searching the Pfam database. Nucleic Acids Res (2004) 1.32
The phosphatidylethanolamine-binding protein is the prototype of a novel family of serine protease inhibitors. J Biol Chem (2001) 1.30
Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem (2005) 1.22
Proteomic analysis of astrocytic secretion in the mouse. Comparison with the cerebrospinal fluid proteome. J Biol Chem (2003) 1.18
Astrocytes generate Na+-mediated metabolic waves. Proc Natl Acad Sci U S A (2004) 1.15
Levels of CSF prostaglandin E2, cognitive decline, and survival in Alzheimer's disease. J Neurol Neurosurg Psychiatry (2005) 1.15
Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension. EMBO J (2004) 1.14
Extracellular matrix degradation by metalloproteinases and central nervous system diseases. Mol Neurobiol (1999) 1.06
Detecting and sorting targeting peptides with neural networks and support vector machines. J Bioinform Comput Biol (2006) 1.03
Clinical response to persistent, low-level beta-glucuronidase expression in the murine model of mucopolysaccharidosis type VII. J Inherit Metab Dis (2007) 1.03
Neurochemical, morphological, and neurophysiological abnormalities in retinas of Sandhoff and GM1 gangliosidosis mice. J Neurochem (2007) 0.94
Role of nerve growth factor and other trophic factors in brain inflammation. Prog Brain Res (2004) 0.93
Secretion of Annexin II via activation of insulin receptor and insulin-like growth factor receptor. J Biol Chem (2002) 0.92
Neuron-astrocyte interactions in the regulation of brain energy metabolism: a focus on NMR spectroscopy. J Neurochem (2006) 0.90
Proteomic analysis of the reactive phenotype of astrocytes following endothelin-1 exposure. Proteomics (2003) 0.90
Difference in mass analysis using labeled lysines (DIMAL-K): a new, efficient proteomic quantification method applied to the analysis of astrocytic secretomes. Mol Cell Proteomics (2005) 0.89
Computational classification of classically secreted proteins. Drug Discov Today (2007) 0.84
Proteome analysis of primary neurons and astrocytes from rat cerebellum. J Proteome Res (2005) 0.84
Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol (2008) 21.53
Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis. J Neurosci (2010) 6.44
Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science (2013) 6.43
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat Rev Drug Discov (2007) 5.65
AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location. Ann Neurol (2009) 4.49
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J Neurosci (2002) 4.38
Forced unfolding of proteins within cells. Science (2007) 3.95
Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating. J Cell Sci (2008) 3.86
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease. J Clin Invest (2004) 3.63
Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations. Free Radic Biol Med (2011) 3.58
The proteome of the mouse photoreceptor sensory cilium complex. Mol Cell Proteomics (2007) 3.53
Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy. J Clin Invest (2008) 3.23
NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. Proc Natl Acad Sci U S A (2003) 2.91
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proc Natl Acad Sci U S A (2007) 2.87
HUPO Plasma Proteome Project specimen collection and handling: towards the standardization of parameters for plasma proteome samples. Proteomics (2005) 2.71
T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. J Clin Invest (2012) 2.66
Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study. Nat Biotechnol (2006) 2.66
Identification of S-nitrosylation motifs by site-specific mapping of the S-nitrosocysteine proteome in human vascular smooth muscle cells. Proc Natl Acad Sci U S A (2006) 2.58
The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat Struct Biol (2002) 2.56
A chromatin remodelling complex that loads cohesin onto human chromosomes. Nature (2002) 2.53
Astrocytes regulate inhibitory synapse formation via Trk-mediated modulation of postsynaptic GABAA receptors. J Neurosci (2005) 2.32
A newly identified role for superoxide in inflammatory pain. J Pharmacol Exp Ther (2004) 2.21
Role of alpha-synuclein carboxy-terminus on fibril formation in vitro. Biochemistry (2003) 2.18
Intracellular and trans-synaptic regulation of glutamatergic synaptogenesis by EphB receptors. J Neurosci (2006) 2.17
Biological significance of nitric oxide-mediated protein modifications. Am J Physiol Lung Cell Mol Physiol (2004) 2.16
Basal and stimulated protein S-nitrosylation in multiple cell types and tissues. J Biol Chem (2002) 2.14
Structural and functional effects of hereditary hemolytic anemia-associated point mutations in the alpha spectrin tetramer site. Blood (2008) 2.12
Depletion of multiple high-abundance proteins improves protein profiling capacities of human serum and plasma. Proteomics (2005) 2.02
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. Proc Natl Acad Sci U S A (2006) 1.90
Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging. Proc Natl Acad Sci U S A (2006) 1.88
Structural profiling of endogenous S-nitrosocysteine residues reveals unique features that accommodate diverse mechanisms for protein S-nitrosylation. Proc Natl Acad Sci U S A (2010) 1.87
A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell (2011) 1.86
Epigenetic regulation of condensin-mediated genome organization during the cell cycle and upon DNA damage through histone H3 lysine 56 acetylation. Mol Cell (2012) 1.85
Isolation of human NURF: a regulator of Engrailed gene expression. EMBO J (2003) 1.80
Systematic discovery of structural elements governing stability of mammalian messenger RNAs. Nature (2012) 1.80
Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis. Ann Neurol (2014) 1.73
Cooperativity in forced unfolding of tandem spectrin repeats. Biophys J (2003) 1.70
A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes. J Biol Chem (2002) 1.67
The functional interactome landscape of the human histone deacetylase family. Mol Syst Biol (2013) 1.63
A novel four-dimensional strategy combining protein and peptide separation methods enables detection of low-abundance proteins in human plasma and serum proteomes. Proteomics (2005) 1.62
Increased expression of LDL receptor-related protein 1 during human cytomegalovirus infection reduces virion cholesterol and infectivity. Cell Host Microbe (2012) 1.59
Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation. J Biol Chem (2004) 1.58
Cdc13 OB2 dimerization required for productive Stn1 binding and efficient telomere maintenance. Structure (2012) 1.56
Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. Mol Cell Proteomics (2012) 1.49
Distinct region-specific alpha-synuclein oligomers in A53T transgenic mice: implications for neurodegeneration. J Neurosci (2010) 1.49
Reactive oxygen and nitrogen species: weapons of neuronal destruction in models of Parkinson's disease. Antioxid Redox Signal (2005) 1.47
Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations. J Biol Chem (2005) 1.47
Pathway shifts and thermal softening in temperature-coupled forced unfolding of spectrin domains. Biophys J (2003) 1.46
Cigarette smoke exposure and hypercholesterolemia increase mitochondrial damage in cardiovascular tissues. Circulation (2002) 1.46
Nitric oxide regulates mitochondrial fatty acid metabolism through reversible protein S-nitrosylation. Sci Signal (2013) 1.45
Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanoma. Cell Rep (2013) 1.43
Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates. J Neurosci (2006) 1.43
The common hereditary elliptocytosis-associated α-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation. Blood (2013) 1.43
Immunoglobulins against tyrosine-nitrated epitopes in coronary artery disease. Circulation (2012) 1.42
Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans. Mitochondrion (2009) 1.41
Pro-thrombotic state induced by post-translational modification of fibrinogen by reactive nitrogen species. J Biol Chem (2003) 1.36
Postsynaptic TrkB-mediated signaling modulates excitatory and inhibitory neurotransmitter receptor clustering at hippocampal synapses. J Neurosci (2004) 1.35
Regulation of protein function and signaling by reversible cysteine S-nitrosylation. J Biol Chem (2013) 1.35
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases. Free Radic Biol Med (2002) 1.32
Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity. Biochem J (2009) 1.32
Landscape of the mitochondrial Hsp90 metabolome in tumours. Nat Commun (2013) 1.29
Effects of oxidative and nitrative challenges on alpha-synuclein fibrillogenesis involve distinct mechanisms of protein modifications. J Biol Chem (2003) 1.29
MYST protein acetyltransferase activity requires active site lysine autoacetylation. EMBO J (2011) 1.29
Endoplasmic reticulum PI(3)P lipid binding targets malaria proteins to the host cell. Cell (2012) 1.26
Erythrocyte detergent-resistant membrane proteins: their characterization and selective uptake during malarial infection. Blood (2003) 1.26
Nitric oxide and reactive oxygen species in Parkinson's disease. IUBMB Life (2003) 1.26
Comparison of extensive protein fractionation and repetitive LC-MS/MS analyses on depth of analysis for complex proteomes. J Proteome Res (2010) 1.25
Astrocyte secreted proteins selectively increase hippocampal GABAergic axon length, branching, and synaptogenesis. Mol Cell Neurosci (2009) 1.22
Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding. Blood (2006) 1.22
Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro. J Neurochem (2003) 1.22
Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria. J Neurosci (2011) 1.18
Dematin and adducin provide a novel link between the spectrin cytoskeleton and human erythrocyte membrane by directly interacting with glucose transporter-1. J Biol Chem (2008) 1.18
Structural basis for dimerization in DNA recognition by Gal4. Structure (2008) 1.16
Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein. Biochemistry (2005) 1.16
Kinesin-3 mediates axonal sorting and directional transport of alphaherpesvirus particles in neurons. Cell Host Microbe (2012) 1.14
Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step. EMBO J (2013) 1.14
Systematic discovery of ectopic pregnancy serum biomarkers using 3-D protein profiling coupled with label-free quantitation. J Proteome Res (2011) 1.14
Subcellular localization of tyrosine-nitrated proteins is dictated by reactive oxygen species generating enzymes and by proximity to nitric oxide synthase. Free Radic Biol Med (2005) 1.13
Mechanisms underlying autoimmune synaptic encephalitis leading to disorders of memory, behavior and cognition: insights from molecular, cellular and synaptic studies. Eur J Neurosci (2010) 1.13
Cellular plasticity induced by anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor encephalitis antibodies. Ann Neurol (2015) 1.13
Neuromuscular synaptogenesis in wild-type and mutant zebrafish. Dev Biol (2005) 1.12
Chemistry on a single protein, vascular cell adhesion molecule-1, during forced unfolding. J Biol Chem (2004) 1.11
Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex. Blood (2010) 1.11
Mammalian tropomodulins nucleate actin polymerization via their actin monomer binding and filament pointed end-capping activities. J Biol Chem (2010) 1.11
Quantitative mass spectrometry-based proteomics reveals the dynamic range of primary mouse astrocyte protein secretion. J Proteome Res (2010) 1.11
Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules. J Biol Chem (2001) 1.10
Neurobeachin is essential for neuromuscular synaptic transmission. J Neurosci (2004) 1.08
Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition. Cell Cycle (2013) 1.08
Cellular oligomerization of alpha-synuclein is determined by the interaction of oxidized catechols with a C-terminal sequence. J Biol Chem (2007) 1.08