Published in Proc Natl Acad Sci U S A on August 01, 2005
Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1. Immunity (2007) 6.36
Setting the stage: host invasion by HIV. Nat Rev Immunol (2008) 3.25
Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus. J Virol (2009) 2.49
HIV transmission. Cold Spring Harb Perspect Med (2012) 1.52
Exogenous and endogenous hyaluronic acid reduces HIV infection of CD4(+) T cells. Immunol Cell Biol (2014) 1.46
Targeting Trojan Horse leukocytes for HIV prevention. AIDS (2010) 1.40
Defining the interaction of HIV-1 with the mucosal barriers of the female reproductive tract. J Virol (2013) 1.31
Modulation of Viscoelasticity and HIV Transport as a Function of pH in a Reversibly Crosslinked Hydrogel. Adv Funct Mater (2009) 1.28
Immune reconstitution of the female reproductive tract of humanized BLT mice and their susceptibility to human immunodeficiency virus infection. J Reprod Immunol (2011) 1.22
How do viral and host factors modulate the sexual transmission of HIV? Can transmission be blocked? PLoS Med (2006) 1.20
Virus movements on the plasma membrane support infection and transmission between cells. PLoS Pathog (2009) 1.17
Barriers to mucosal transmission of immunodeficiency viruses. Blood (2011) 1.14
HIV-1 transmission biology: selection and characteristics of infecting viruses. J Infect Dis (2010) 1.11
Innate and adaptive anti-HIV immune responses in the female reproductive tract. J Reprod Immunol (2013) 1.09
Cervico-vaginal tissue ex vivo as a model to study early events in HIV-1 infection. Am J Reprod Immunol (2011) 1.00
Helical conformation of the SEVI precursor peptide PAP248-286, a dramatic enhancer of HIV infectivity, promotes lipid aggregation and fusion. Biophys J (2009) 1.00
Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia. J Virol (2011) 0.99
HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells. Virology (2010) 0.99
Expression of HIV receptors, alternate receptors and co-receptors on tonsillar epithelium: implications for HIV binding and primary oral infection. Virol J (2006) 0.95
Caveats associated with the use of human cervical tissue for HIV and microbicide research. AIDS (2010) 0.95
In situ distribution of HIV-binding CCR5 and C-type lectin receptors in the human endocervical mucosa. PLoS One (2011) 0.94
Human cytomegalovirus and human immunodeficiency virus type-1 co-infection in human cervical tissue. Virology (2007) 0.93
Ex vivo comparison of microbicide efficacies for preventing HIV-1 genomic integration in intraepithelial vaginal cells. Antimicrob Agents Chemother (2009) 0.93
R5 HIV-1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5. EMBO Mol Med (2013) 0.93
C. albicans colonization of human mucosal surfaces. PLoS One (2008) 0.92
Herpes simplex virus-induced epithelial damage and susceptibility to human immunodeficiency virus type 1 infection in human cervical organ culture. PLoS One (2011) 0.92
Defective virus drives human immunodeficiency virus infection, persistence, and pathogenesis. Clin Vaccine Immunol (2006) 0.89
Transient antibody-mucin interactions produce a dynamic molecular shield against viral invasion. Biophys J (2014) 0.87
Blocking of integrins inhibits HIV-1 infection of human cervical mucosa immune cells with free and complement-opsonized virions. Eur J Immunol (2013) 0.86
MIV-150/zinc acetate gel inhibits cell-associated simian-human immunodeficiency virus reverse transcriptase infection in a macaque vaginal explant model. Antimicrob Agents Chemother (2015) 0.86
Human immunodeficiency virus type 1 (HIV-1) integration: a potential target for microbicides to prevent cell-free or cell-associated HIV-1 infection. Antimicrob Agents Chemother (2008) 0.85
Modeling mucosal cell-associated HIV type 1 transmission in vitro. J Infect Dis (2014) 0.84
BLT humanized mice as model to study HIV vaginal transmission. J Infect Dis (2013) 0.84
Modeling neutralization kinetics of HIV by broadly neutralizing monoclonal antibodies in genital secretions coating the cervicovaginal mucosa. PLoS One (2014) 0.84
Inhibition of the transport of HIV in vitro using a pH-responsive synthetic mucin-like polymer system. Biomaterials (2011) 0.84
Transcytosis of HIV-1 through vaginal epithelial cells is dependent on trafficking to the endocytic recycling pathway. PLoS One (2014) 0.83
The importance of the vaginal delivery route for antiretrovirals in HIV prevention. Ther Deliv (2011) 0.81
Mucosal immunity in the female genital tract, HIV/AIDS. Biomed Res Int (2014) 0.81
HIV-1 vaginal transmission: cell-free or cell-associated virus? Am J Reprod Immunol (2014) 0.81
Oral and vaginal epithelial cell lines bind and transfer cell-free infectious HIV-1 to permissive cells but are not productively infected. PLoS One (2014) 0.80
ART influences HIV persistence in the female reproductive tract and cervicovaginal secretions. J Clin Invest (2016) 0.80
Regulation of inflammatory pathways in cancer and infectious disease of the cervix. Scientifica (Cairo) (2012) 0.79
HIV type 1 fails to trigger innate immune factor synthesis in differentiated oral epithelium. AIDS Res Hum Retroviruses (2009) 0.78
The role of dendritic cells in driving genital tract inflammation and HIV transmission risk: are there opportunities to intervene? Innate Immun (2013) 0.77
Inhibition of HIV-1 infection in ex vivo cervical tissue model of human vagina by palmitic acid; implications for a microbicide development. PLoS One (2011) 0.77
The regulation of inflammatory pathways and infectious disease of the cervix by seminal fluid. Patholog Res Int (2014) 0.75
Imaging and tracking HIV viruses in human cervical mucus. J Biomed Opt (2016) 0.75
Visualization of X4- and R5-Tropic HIV-1 Viruses Expressing Fluorescent Proteins in Human Endometrial Cells: Application to Tropism Study. PLoS One (2017) 0.75
Human Immunodeficiency Virus (HIV). Transfus Med Hemother (2016) 0.75
Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group. N Engl J Med (2000) 41.18
DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell (2000) 14.43
Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda. Lancet (2001) 13.32
Brief but efficient: acute HIV infection and the sexual transmission of HIV. J Infect Dis (2004) 8.30
Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells. Science (1999) 7.66
The role of sexually transmitted diseases in HIV transmission. Nat Rev Microbiol (2004) 7.04
Sexual transmission of HIV. N Engl J Med (1997) 6.84
A systematic review of the epidemiologic interactions between classic sexually transmitted diseases and HIV: how much really is known? Sex Transm Dis (2001) 4.73
Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides. J Virol (2000) 3.68
Transmission, acute HIV-1 infection and the quest for strategies to prevent infection. Nat Med (2003) 3.48
Development of an in vitro organ culture model to study transmission of HIV-1 in the female genital tract. Nat Med (2000) 3.30
Recent observations on HIV type-1 infection in the genital tract of men and women. AIDS (2003) 2.97
DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus. J Virol (2001) 2.95
Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue. J Exp Med (2004) 2.58
HIV-1 attachment: another look. Trends Microbiol (1999) 2.23
The vaginal microbial ecosystem and resistance to HIV. AIDS Res Hum Retroviruses (1998) 2.12
Antigen sampling across epithelial barriers and induction of mucosal immune responses. Annu Rev Immunol (1996) 2.11
Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor. Proc Natl Acad Sci U S A (1993) 1.96
T lymphocytes and macrophages, but not motile spermatozoa, are a significant source of human immunodeficiency virus in semen. J Infect Dis (1997) 1.85
The tissue distribution of T lymphocytes expressing different CD45 polypeptides. Immunology (1989) 1.52
High levels of tumor necrosis factor-alpha and interleukin-1beta in bacterial vaginosis may increase susceptibility to human immunodeficiency virus. J Infect Dis (2000) 1.40
Cervical and prostate primary epithelial cells are not productively infected but sequester human immunodeficiency virus type 1. J Infect Dis (2001) 1.33
Cyclic shedding of HIV-1 RNA in cervical secretions during the menstrual cycle. J Infect Dis (2004) 1.31
Human genital epithelial cells capture cell-free human immunodeficiency virus type 1 and transmit the virus to CD4+ Cells: implications for mechanisms of sexual transmission. J Infect Dis (2003) 1.29
Blocking of cell-free and cell-associated HIV-1 transmission through human cervix organ culture with UC781. AIDS (2003) 1.10
In vitro models of mucosal HIV transmission. Nat Med (2000) 1.09
In vitro HIV1 infection of human cervical tissue. Res Virol (1995) 1.06
Semen analysis in human immunodeficiency virus infection. Fertil Steril (1992) 1.03
Heparin-binding domain of human fibronectin binds HIV-1 gp120/160 and reduces virus infectivity. J Med Virol (1998) 0.95
Mammary epithelial cells support and transfer productive human T-cell lymphotropic virus infections. J Hum Virol (1999) 0.94
Sensitive method for the detection of infectious HIV in semen of seropositive individuals. J Virol Methods (1996) 0.93
Ex vivo modeling of oral HIV transmission in human palatine tonsil. J Histochem Cytochem (2005) 0.93
A cytokine switch induced by human seminal plasma: an immune modulation with implications for sexually transmitted disease. Hum Reprod (1997) 0.91
Factors associated with changes in HIV shedding in semen. AIDS Res Hum Retroviruses (1998) 0.91
Interaction of human immunodeficiency virus type 1 envelope glycoprotein gp120 with a galactoglycerolipid associated with human sperm. AIDS Res Hum Retroviruses (1996) 0.89
A model system of oral HIV exposure, using human palatine tonsil, reveals extensive binding of HIV infectivity, with limited progression to primary infection. J Infect Dis (2004) 0.87
Reply to 'In vitro models of mucosal HIV transmission' Nat Med (2000) 0.81
Modulation of integrin function inhibits HIV transmission to epithelial cells and fertilization. J Reprod Immunol (1998) 0.79
Sperm as infection-potentiating cofactors in HIV transmission. J Reprod Immunol (1998) 0.79
Antibody neutralization and escape by HIV-1. Nature (2003) 21.48
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy. Antimicrob Agents Chemother (2002) 13.91
PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection. J Exp Med (2006) 8.18
Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood (2008) 4.34
Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells. Nat Med (2002) 3.04
Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection. J Infect Dis (2006) 3.04
Functional genomic analysis of the response of HIV-1-infected lymphatic tissue to antiretroviral therapy. J Infect Dis (2004) 2.68
Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. PLoS Pathog (2013) 2.44
Simian immunodeficiency virus-induced intestinal cell apoptosis is the underlying mechanism of the regenerative enteropathy of early infection. J Infect Dis (2008) 1.94
Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection. J Infect Dis (2007) 1.87
Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy. Cancer Res (2009) 1.70
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants. Nature (2009) 1.63
Oxidative capacity in failing hearts. Am J Physiol Heart Circ Physiol (2003) 1.51
The Ess1 prolyl isomerase is required for transcription termination of small noncoding RNAs via the Nrd1 pathway. Mol Cell (2009) 1.35
Evidence that stable retroviral transduction and cell survival following DNA integration depend on components of the nonhomologous end joining repair pathway. J Virol (2004) 1.32
Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers. PLoS One (2013) 1.19
Prolyl isomerases in yeast. Front Biosci (2004) 1.10
ELISA for human serum leucine-rich alpha-2-glycoprotein-1 employing cytochrome c as the capturing ligand. J Immunol Methods (2008) 1.09
Production of trans-lentiviral vector with predictable safety. Methods Mol Med (2003) 1.02
Human pluripotent stem cells produce natural killer cells that mediate anti-HIV-1 activity by utilizing diverse cellular mechanisms. J Virol (2010) 1.01
Vanishingly low levels of Ess1 prolyl-isomerase activity are sufficient for growth in Saccharomyces cerevisiae. J Biol Chem (2005) 0.97
Cytomegalovirus blocks intestinal stroma-induced down-regulation of macrophage HIV-1 infection. J Leukoc Biol (2006) 0.97
Knockdown of cellular RNA helicase DDX3 by short hairpin RNAs suppresses HIV-1 viral replication without inducing apoptosis. Mol Biotechnol (2008) 0.93
Neurologic abnormalities in workers of a 1-bromopropane factory. Environ Health Perspect (2004) 0.92
C. albicans colonization of human mucosal surfaces. PLoS One (2008) 0.92
The DEAD-box RNA helicase DDX1 interacts with RelA and enhances nuclear factor kappaB-mediated transcription. J Cell Biochem (2009) 0.92
Inhibiting replication of begomoviruses using artificial zinc finger nucleases that target viral-conserved nucleotide motif. Virus Genes (2014) 0.92
Subunit-specific analysis of the human immunodeficiency virus type 1 reverse transcriptase in vivo. J Virol (2004) 0.91
Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells. J Clin Invest (2015) 0.90
CpG usage in RNA viruses: data and hypotheses. PLoS One (2013) 0.89
Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications. Protein Eng Des Sel (2011) 0.89
Specific inhibition of HIV-1 replication by short hairpin RNAs targeting human cyclin T1 without inducing apoptosis. FEBS Lett (2005) 0.89
The promoter of the human proliferating cell nuclear antigen gene is not sufficient for cell cycle-dependent regulation in organotypic cultures of keratinocytes. J Biol Chem (2002) 0.88
Replication of chimeric human immunodeficiency virus type 1 (HIV-1) containing HIV-2 integrase (IN): naturally selected mutations in IN augment DNA synthesis. J Virol (2003) 0.88
Development of IL-22-producing NK lineage cells from umbilical cord blood hematopoietic stem cells in the absence of secondary lymphoid tissue. Blood (2011) 0.87
A model system of oral HIV exposure, using human palatine tonsil, reveals extensive binding of HIV infectivity, with limited progression to primary infection. J Infect Dis (2004) 0.87
Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. BMC Genomics (2013) 0.85
A kinetic comparison of asparagine synthetase isozymes from higher plants. Plant Physiol Biochem (2010) 0.85
Upregulation of GRP78 in renal cell carcinoma and its significance. Urology (2009) 0.83
2,4-Diaminopyrimidine MK2 inhibitors. Part II: Structure-based inhibitor optimization. Bioorg Med Chem Lett (2009) 0.83
Changes in the prevalence of visual impairment due to blinding trachoma in Sichuan province, China: a comparative study between 1987 and 2006. Ophthalmic Epidemiol (2011) 0.80
An update on short-course episodic and prevention therapies for herpes genitalis. Herpes (2007) 0.80
Presynaptic GABA(B) Receptor Regulates Activity-Dependent Maturation and Patterning of Inhibitory Synapses through Dynamic Allocation of Synaptic Vesicles. Front Cell Neurosci (2012) 0.79
Functional investigations on embryonic stem cells labeled with clinically translatable iron oxide nanoparticles. Nanoscale (2014) 0.79
Inhibition of HIV-1 transcription and replication by a newly identified cyclin T1 splice variant. J Biol Chem (2013) 0.79
Cellular mechanism for milk-borne transmission of HIV and HTLV. Adv Exp Med Biol (2002) 0.78
Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells. J Biomed Sci (2009) 0.78
Thienopyrrole acetic acids as antagonists of the CRTH2 receptor. Bioorg Med Chem Lett (2011) 0.78
4β-Hydroxycholesterol as an endogenous biomarker of CYP3A activity in cynomolgus monkeys. Drug Metab Dispos (2014) 0.77
Imiquimod and genital herpes. Arch Dermatol (2002) 0.76
New tools to track HIV. Nat Med (2010) 0.76
Single embryonic stem cell-derived embryoid bodies for gene screening. Biotechniques (2005) 0.76
Clinician and patient recognition of anogenital herpes disease in HIV positive men who have sex with men. Sex Transm Dis (2011) 0.75
Immunolocalization of novel corticomedullary tubule injury markers in Cynomolgus monkeys treated with amphotericin B. J Toxicol Sci (2017) 0.75
Study of optical parameters of polystyrene spheres in dense aqueous suspensions. Appl Opt (2012) 0.75
Molecular diagnosis of a Chinese pedigree with α-mannosidosis and identification of a novel missense mutation. J Pediatr Endocrinol Metab (2014) 0.75
Nicorandil improves myocardial high-energy phosphates in postinfarction porcine hearts. Clin Exp Pharmacol Physiol (2002) 0.75
High-throughput Phenotyping of Lung Cancer Somatic Mutations. Cancer Cell (2017) 0.75
Accuracy of herpes simplex virus detection in liquid-based (SurePath) Papanicolaou tests: a comparison with polymerase chain reaction. Diagn Cytopathol (2008) 0.75