Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy.

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Published in Cancer Res on November 17, 2009

Authors

Lei Fu1, Young-Ae Kim, Xuerong Wang, Xiaoyun Wu, Ping Yue, Sagar Lonial, Fadlo R Khuri, Shi-Yong Sun

Author Affiliations

1: Department of Hematology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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