Published in J Am Chem Soc on August 10, 2005
Fluorescent analogs of biomolecular building blocks: design, properties, and applications. Chem Rev (2010) 2.16
Synthesis and properties of size-expanded DNAs: toward designed, functional genetic systems. Acc Chem Res (2007) 1.36
Crown ether-electrolyte interactions permit nanopore detection of individual DNA abasic sites in single molecules. Proc Natl Acad Sci U S A (2012) 1.23
Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization. J Am Chem Soc (2007) 1.23
Emissive RNA alphabet. J Am Chem Soc (2011) 1.22
Characterization and use of an unprecedentedly bright and structurally non-perturbing fluorescent DNA base analogue. Nucleic Acids Res (2007) 1.13
FRET enabled real time detection of RNA-small molecule binding. J Am Chem Soc (2009) 1.11
Sensitivity of Ru(bpy)2dppz2+ luminescence to DNA defects. Inorg Chem (2009) 1.05
Exploring the limits of DNA size: naphtho-homologated DNA bases and pairs. J Am Chem Soc (2006) 1.04
A highly fluorescent nucleoside analog based on thieno[3,4-d]pyrimidine senses mismatched pairing. Org Biomol Chem (2008) 1.03
A highly emissive fluorescent nucleoside that signals the activity of toxic ribosome-inactivating proteins. Angew Chem Int Ed Engl (2008) 1.02
Oligodeoxyfluorosides: Strong Sequence Dependence of Fluorescence Emission. Tetrahedron (2007) 0.99
An emissive C analog distinguishes between G, 8-oxoG, and T. Org Lett (2009) 0.97
Emissive nucleosides as molecular rotors. Chemphyschem (2010) 0.95
Investigating the biochemical impact of DNA damage with structure-based probes: abasic sites, photodimers, alkylation adducts, and oxidative lesions. Biochemistry (2009) 0.93
DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes. Angew Chem Int Ed Engl (2013) 0.88
Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine. Org Biomol Chem (2010) 0.87
Enzymatic interconversion of isomorphic fluorescent nucleosides: adenosine deaminase transforms an adenosine analogue into an inosine analogue. Angew Chem Int Ed Engl (2013) 0.86
Using an emissive uridine analogue for assembling fluorescent HIV-1 TAR constructs. Tetrahedron (2007) 0.85
Enzymatic incorporation of emissive pyrimidine ribonucleotides. Chem Asian J (2009) 0.84
Modified 6-aza uridines: highly emissive pH-sensitive fluorescent nucleosides. Chemphyschem (2012) 0.83
Design, synthesis, and spectroscopic properties of extended and fused pyrrolo-dC and pyrrolo-C analogs. Org Lett (2012) 0.82
Multisensing emissive pyrimidine. Chemphyschem (2011) 0.82
Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA. Nucleic Acids Res (2011) 0.81
Chemical Mutagenesis of an Emissive RNA Alphabet. J Am Chem Soc (2015) 0.79
"Reverse" carbocyclic fleximers: synthesis of a new class of adenosine deaminase inhibitors. Nucleosides Nucleotides Nucleic Acids (2013) 0.79
Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA. J Am Chem Soc (2011) 0.78
Two-photon-induced fluorescence of isomorphic nucleobase analogs. Chemphyschem (2014) 0.78
Visibly emissive and responsive extended 6-aza-uridines. Org Lett (2014) 0.78
Oligodeoxynucleotides containing multiple thiophene-modified isomorphic fluorescent nucleosides. J Org Chem (2013) 0.76
Recognition of O6-benzyl-2'-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction. Nucleic Acids Res (2013) 0.76
Development of bright fluorescent quadracyclic adenine analogues: TDDFT-calculation supported rational design. Sci Rep (2015) 0.76
Theoretical study on absorption and emission spectra of adenine analogues. J Mol Model (2014) 0.76
Enzymatic incorporation and utilization of an emissive 6-azauridine. Org Biomol Chem (2016) 0.75
Palladium-catalyzed direct arylation of 5-halouracils and 5-halouracil nucleosides with arenes and heteroarenes promoted by TBAF. J Org Chem (2014) 0.75
Fluorescent analogs of biomolecular building blocks: design, properties, and applications. Chem Rev (2010) 2.16
Antibiotics that target protein synthesis. Wiley Interdiscip Rev RNA (2010) 1.43
Cellular uptake of aminoglycosides, guanidinoglycosides, and poly-arginine. J Am Chem Soc (2003) 1.31
Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions. Biochemistry (2006) 1.28
Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A (2008) 1.26
Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization. J Am Chem Soc (2007) 1.23
Emissive RNA alphabet. J Am Chem Soc (2011) 1.22
A boost for the emerging field of RNA nanotechnology. ACS Nano (2011) 1.17
Nanopore analysis of individual RNA/antibiotic complexes. ACS Nano (2011) 1.14
Conformational constraint as a means for understanding RNA-aminoglycoside specificity. J Am Chem Soc (2005) 1.11
FRET enabled real time detection of RNA-small molecule binding. J Am Chem Soc (2009) 1.11
Donor/acceptor interactions in systematically modified Ru(II)-Os(II) oligonucleotides. J Am Chem Soc (2002) 1.11
Molecular recognition of RNA by neomycin and a restricted neomycin derivative. Angew Chem Int Ed Engl (2005) 1.10
RNA-ligand interactions: affinity and specificity of aminoglycoside dimers and acridine conjugates to the HIV-1 Rev response element. Biochemistry (2003) 1.08
Guanidinylated neomycin delivers large, bioactive cargo into cells through a heparan sulfate-dependent pathway. J Biol Chem (2007) 1.07
Fluorescence-based methods for evaluating the RNA affinity and specificity of HIV-1 Rev-RRE inhibitors. Biopolymers (2003) 1.05
A highly fluorescent nucleoside analog based on thieno[3,4-d]pyrimidine senses mismatched pairing. Org Biomol Chem (2008) 1.03
Polarity of major grooves explored by using an isosteric emissive nucleoside. Chembiochem (2008) 1.02
A highly emissive fluorescent nucleoside that signals the activity of toxic ribosome-inactivating proteins. Angew Chem Int Ed Engl (2008) 1.02
Furan Decorated Nucleoside Analogues as Fluorescent Probes: synthesis, photophysical evaluation and site-specific incorporation. Tetrahedron (2007) 1.02
On the electronic structure of ethidium. Chemistry (2005) 0.99
An emissive C analog distinguishes between G, 8-oxoG, and T. Org Lett (2009) 0.97
Deoxygenated disaccharide analogs as specific inhibitors of beta1-4-galactosyltransferase 1 and selectin-mediated tumor metastasis. J Biol Chem (2008) 0.96
Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites. Chem Commun (Camb) (2010) 0.96
Guanidinoneomycin B recognition of an HIV-1 RNA helix. Chembiochem (2008) 0.96
To D or not to D? On estimating the microenvironment polarity of biomolecular cavities. Org Biomol Chem (2007) 0.96
Emissive nucleosides as molecular rotors. Chemphyschem (2010) 0.95
Using pyrene-labeled HIV-1 TAR to measure RNA-small molecule binding. Nucleic Acids Res (2003) 0.95
Fluorescent ribonucleoside as a FRET acceptor for tryptophan in native proteins. J Am Chem Soc (2010) 0.94
Binding of aminoglycosidic antibiotics to the oligonucleotide A-site model and 30S ribosomal subunit: Poisson-Boltzmann model, thermal denaturation, and fluorescence studies. J Med Chem (2006) 0.94
Cooperative, heparan sulfate-dependent cellular uptake of dimeric guanidinoglycosides. Chembiochem (2010) 0.93
Fluorescent HIV-1 Dimerization Initiation Site: design, properties, and use for ligand discovery. J Am Chem Soc (2007) 0.92
Monitoring translation with modified mRNAs strategically labeled with isomorphic fluorescent guanosine mimetics. ACS Chem Biol (2013) 0.91
Selectively guanidinylated aminoglycosides as antibiotics. ChemMedChem (2012) 0.91
Ru(II) and Os(II) nucleosides and oligonucleotides: synthesis and properties. J Am Chem Soc (2002) 0.91
Synthesis and enzymatic incorporation of a fluorescent pyrimidine ribonucleotide. Nat Protoc (2007) 0.91
RNA-selective modification by a platinum(II) complex conjugated to amino- and guanidinoglycosides. Angew Chem Int Ed Engl (2005) 0.91
Mechanical properties of DNA-like polymers. Nucleic Acids Res (2013) 0.89
A tale of two targets: differential RNA selectivity of nucleobase-aminoglycoside conjugates. Chembiochem (2006) 0.89
Guanidinylated neomycin mediates heparan sulfate-dependent transport of active enzymes to lysosomes. Mol Ther (2010) 0.89
Synthesis and site-specific incorporation of a simple fluorescent pyrimidine. Nat Protoc (2007) 0.89
Eilatin Ru(II) complexes display anti-HIV activity and enantiomeric diversity in the binding of RNA. Chembiochem (2002) 0.87
Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine. Org Biomol Chem (2010) 0.87
Isomorphic emissive GTP surrogate facilitates initiation and elongation of in vitro transcription reactions. J Am Chem Soc (2014) 0.86
Enzymatic interconversion of isomorphic fluorescent nucleosides: adenosine deaminase transforms an adenosine analogue into an inosine analogue. Angew Chem Int Ed Engl (2013) 0.86
Aggregation-mediated macromolecular uptake by a molecular transporter. ACS Chem Biol (2013) 0.86
Conquering 2-aminopurine's deficiencies: highly emissive isomorphic guanosine surrogate faithfully monitors guanosine conformation and dynamics in DNA. J Am Chem Soc (2015) 0.85
Using an emissive uridine analogue for assembling fluorescent HIV-1 TAR constructs. Tetrahedron (2007) 0.85
Redox-active metal-containing nucleotides: synthesis, tunability, and enzymatic incorporation into DNA. J Am Chem Soc (2002) 0.84
Enzymatic incorporation of emissive pyrimidine ribonucleotides. Chem Asian J (2009) 0.84
Fluorescent 1,10-phenanthroline-containing oligonucleotides distinguish between perfect and mismatched base pairing. Org Lett (2002) 0.84
Polyamide platinum anticancer complexes designed to target specific DNA sequences. Inorg Chem (2006) 0.83
Modified 6-aza uridines: highly emissive pH-sensitive fluorescent nucleosides. Chemphyschem (2012) 0.83
Simple conversion of aromatic amines into azides. Org Lett (2003) 0.83
Inhibition of nuclear import mediated by the Rev-arginine rich motif by RNA molecules. Biochemistry (2003) 0.83
Dual emission from a family of conjugated dinuclear Ru(II) complexes. J Am Chem Soc (2005) 0.82
Design, synthesis, and spectroscopic properties of extended and fused pyrrolo-dC and pyrrolo-C analogs. Org Lett (2012) 0.82
Multisensing emissive pyrimidine. Chemphyschem (2011) 0.82
Photodimerizable ditopic ligand. Org Lett (2006) 0.81
New macrocyclic terbium(III) complex for use in RNA footprinting experiments. J Am Chem Soc (2009) 0.81
The DNA and RNA specificity of eilatin Ru(II) complexes as compared to eilatin and ethidium bromide. Nucleic Acids Res (2003) 0.81
Cleavage of RNA oligonucleotides by aminoglycosides. Org Biomol Chem (2008) 0.81
Polymyxins and analogues bind to ribosomal RNA and interfere with eukaryotic translation in vitro. Chembiochem (2013) 0.81
Synthesis and stability of exocyclic triazine nucleosides. Org Biomol Chem (2005) 0.81
Synthesis, photophysical properties, and nucleic acid binding of phenanthridinium derivatives based on ethidium. Bioorg Med Chem (2003) 0.80
Defining the molecular forces that determine the impact of neomycin on bacterial protein synthesis: importance of the 2'-amino functionality. Antimicrob Agents Chemother (2007) 0.80
Synthesis of N-methylpyrrole and N-methylimidazole amino acids suitable for solid-phase synthesis. J Org Chem (2004) 0.80
On guanidinium and cellular uptake. J Org Chem (2014) 0.79
Cellular activity of siRNA oligonucleotides containing synthetic isomorphic nucleoside surrogates. Chem Commun (Camb) (2015) 0.79
Extended ethidium bromide analogue as a triple helix intercalator: synthesis, photophysical properties and nucleic acids binding. Chem Commun (Camb) (2006) 0.79
Binding of HIV-1 TAR mRNA to a peptide nucleic acid oligomer and its conjugates with metal-ion-binding multidentate ligands. J Biol Inorg Chem (2008) 0.79
RuII complexes of "large-surface" ligands. Angew Chem Int Ed Engl (2002) 0.79
Two-photon-induced fluorescence of isomorphic nucleobase analogs. Chemphyschem (2014) 0.78
MDDD, a 4,9-diazapyrenium derivative, is selectively toxic to glioma cells by inducing growth arrest at G0/G1 independently of p53. Invest New Drugs (2006) 0.78
Visibly emissive and responsive extended 6-aza-uridines. Org Lett (2014) 0.78
Bifacial nucleoside as a surrogate for both T and A in duplex DNA. J Am Chem Soc (2011) 0.78
Ruthenium complexes that break the rules: structural features controlling dual emission. J Am Chem Soc (2007) 0.78
Genetic alphabetic order: what came before A? Org Biomol Chem (2005) 0.77
Refining the genetic alphabet: a late-period selection pressure? Astrobiology (2012) 0.77
Singly modified amikacin and tobramycin derivatives show increased rRNA A-site binding and higher potency against resistant bacteria. ChemMedChem (2014) 0.76
Model systems: how chemical biologists study RNA. Curr Opin Chem Biol (2009) 0.76
Direct observation of aminoglycoside-RNA binding by localized surface plasmon resonance spectroscopy. Anal Chem (2013) 0.76
Oligodeoxynucleotides containing multiple thiophene-modified isomorphic fluorescent nucleosides. J Org Chem (2013) 0.76
Macromolecular uptake of alkyl-chain-modified guanidinoglycoside molecular transporters. Chembiochem (2014) 0.76
Citric acid and the RNA world. Angew Chem Int Ed Engl (2014) 0.75
Application of Surface Click Reactions to Localized Surface Plasmon Resonance (LSPR) Biosensing. Chemistry (2017) 0.75
Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+. Chem Commun (Camb) (2004) 0.75
Alkyne-containing chelating ligands: synthesis, properties and metal coordination of 1,2-di(quinolin-8-yl)ethyne. Dalton Trans (2006) 0.75
Emissive synthetic cofactors: An isomorphic, isofunctional and re-sponsive NAD+ analogue. J Am Chem Soc (2017) 0.75