Published in J Biol Chem on February 20, 2007
Heparan sulfate proteoglycans. Cold Spring Harb Perspect Biol (2011) 2.96
The design of guanidinium-rich transporters and their internalization mechanisms. Adv Drug Deliv Rev (2007) 1.91
Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice. J Clin Invest (2009) 1.56
Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions. Proc Natl Acad Sci U S A (2011) 1.42
Revised role of glycosaminoglycans in TAT protein transduction domain-mediated cellular transduction. J Biol Chem (2009) 1.31
Heparan sulfate 2-O-sulfotransferase is required for triglyceride-rich lipoprotein clearance. J Biol Chem (2009) 1.13
Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice. Proc Natl Acad Sci U S A (2007) 1.12
Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells. J Am Chem Soc (2008) 1.06
Molecular basis for nanoscopic membrane curvature generation from quantum mechanical models and synthetic transporter sequences. J Am Chem Soc (2012) 0.96
Cooperative, heparan sulfate-dependent cellular uptake of dimeric guanidinoglycosides. Chembiochem (2010) 0.93
Beyond Cell Penetrating Peptides: Designed Molecular Transporters. Drug Discov Today Technol (2012) 0.92
Towards a therapy for phosphomannomutase 2 deficiency, the defect in CDG-Ia patients. Biochim Biophys Acta (2009) 0.92
Hepatic remnant lipoprotein clearance by heparan sulfate proteoglycans and low-density lipoprotein receptors depend on dietary conditions in mice. Arterioscler Thromb Vasc Biol (2013) 0.90
Guanidinylated neomycin mediates heparan sulfate-dependent transport of active enzymes to lysosomes. Mol Ther (2010) 0.89
Aggregation-mediated macromolecular uptake by a molecular transporter. ACS Chem Biol (2013) 0.86
On guanidinium and cellular uptake. J Org Chem (2014) 0.79
Anti-inflammatory effects of tobramycin and a copper-tobramycin complex with superoxide dismutase-like activity. Br J Pharmacol (2013) 0.78
Macromolecular uptake of alkyl-chain-modified guanidinoglycoside molecular transporters. Chembiochem (2014) 0.76
Polymyxins Facilitate Entry into Mammalian Cells. Chem Sci (2016) 0.75
Heparan sulphate proteoglycans fine-tune mammalian physiology. Nature (2007) 7.87
The sweet and sour of cancer: glycans as novel therapeutic targets. Nat Rev Cancer (2005) 5.98
Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses. Nat Immunol (2005) 3.82
Heparan sulfate proteoglycans. Cold Spring Harb Perspect Biol (2011) 2.96
Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells. Cell Host Microbe (2007) 2.64
Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members. J Clin Invest (2007) 2.53
Fluorescent analogs of biomolecular building blocks: design, properties, and applications. Chem Rev (2010) 2.16
Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins. J Clin Invest (2002) 1.91
Evolutionary differences in glycosaminoglycan fine structure detected by quantitative glycan reductive isotope labeling. J Biol Chem (2008) 1.91
Mice deficient in Ext2 lack heparan sulfate and develop exostoses. Development (2005) 1.84
Disaccharide structure code for the easy representation of constituent oligosaccharides from glycosaminoglycans. Nat Methods (2008) 1.84
Demystifying heparan sulfate-protein interactions. Annu Rev Biochem (2014) 1.76
Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice. J Biol Chem (2008) 1.73
Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesis. Nature (2003) 1.73
Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function. Development (2005) 1.69
Bacterial dispersal associated with speech in the setting of intravitreous injections. Arch Ophthalmol (2011) 1.68
Multicenter study evaluating the Vitek MS system for identification of medically important yeasts. J Clin Microbiol (2013) 1.64
New Delhi metallo-β-lactamase (NDM-1)-producing Klebsiella pneumoniae: case report and laboratory detection strategies. J Clin Microbiol (2011) 1.61
Multicenter evaluation of the Vitek MS matrix-assisted laser desorption ionization-time of flight mass spectrometry system for identification of Gram-positive aerobic bacteria. J Clin Microbiol (2013) 1.56
Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice. J Clin Invest (2009) 1.56
Symbol nomenclature for glycan representation. Proteomics (2009) 1.56
Heparan sulfate and syndecan-1 are essential in maintaining murine and human intestinal epithelial barrier function. J Clin Invest (2008) 1.52
A focused microarray approach to functional glycomics: transcriptional regulation of the glycome. Glycobiology (2005) 1.49
Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development. Development (2006) 1.46
Antibiotics that target protein synthesis. Wiley Interdiscip Rev RNA (2010) 1.43
Disease-specific non-reducing end carbohydrate biomarkers for mucopolysaccharidoses. Nat Chem Biol (2012) 1.43
Simple fluorescent pyrimidine analogues detect the presence of DNA abasic sites. J Am Chem Soc (2005) 1.42
Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease. PLoS One (2010) 1.42
Resistance to a bacterial toxin is mediated by removal of a conserved glycosylation pathway required for toxin-host interactions. J Biol Chem (2003) 1.41
A dumbbell-shaped small molecule that promotes cell adhesion and growth. Chem Biol (2009) 1.39
Repulsive axon guidance molecule Slit3 is a novel angiogenic factor. Blood (2009) 1.37
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis. J Cell Biol (2007) 1.36
Cellular heparan sulfate participates in the metabolism of prions. J Biol Chem (2003) 1.34
Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes. Biochim Biophys Acta (2002) 1.34
Cellular uptake of aminoglycosides, guanidinoglycosides, and poly-arginine. J Am Chem Soc (2003) 1.31
Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2. J Cell Biol (2006) 1.29
Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions. Biochemistry (2006) 1.28
Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction. Development (2007) 1.27
Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A (2008) 1.26
Essential alterations of heparan sulfate during the differentiation of embryonic stem cells to Sox1-enhanced green fluorescent protein-expressing neural progenitor cells. Stem Cells (2007) 1.23
Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization. J Am Chem Soc (2007) 1.23
Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion. J Virol (2004) 1.23
Functional UDP-xylose transport across the endoplasmic reticulum/Golgi membrane in a Chinese hamster ovary cell mutant defective in UDP-xylose Synthase. J Biol Chem (2008) 1.23
Emissive RNA alphabet. J Am Chem Soc (2011) 1.22
Lacrimal gland development and Fgf10-Fgfr2b signaling are controlled by 2-O- and 6-O-sulfated heparan sulfate. J Biol Chem (2011) 1.19
Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling. Glycobiology (2002) 1.18
A boost for the emerging field of RNA nanotechnology. ACS Nano (2011) 1.17
A disaccharide precursor of sialyl Lewis X inhibits metastatic potential of tumor cells. Cancer Res (2003) 1.16
Hereditary multiple exostoses and heparan sulfate polymerization. Biochim Biophys Acta (2002) 1.15
Nanopore analysis of individual RNA/antibiotic complexes. ACS Nano (2011) 1.14
Heparan sulfate 2-O-sulfotransferase is required for triglyceride-rich lipoprotein clearance. J Biol Chem (2009) 1.13
Conformational constraint as a means for understanding RNA-aminoglycoside specificity. J Am Chem Soc (2005) 1.11
FRET enabled real time detection of RNA-small molecule binding. J Am Chem Soc (2009) 1.11
Donor/acceptor interactions in systematically modified Ru(II)-Os(II) oligonucleotides. J Am Chem Soc (2002) 1.11
Molecular recognition of RNA by neomycin and a restricted neomycin derivative. Angew Chem Int Ed Engl (2005) 1.10
Tumor attenuation by combined heparan sulfate and polyamine depletion. Proc Natl Acad Sci U S A (2001) 1.09
Metabolic engineering of Chinese hamster ovary cells: towards a bioengineered heparin. Metab Eng (2012) 1.09
Heparan 2-O-sulfotransferase, hst-2, is essential for normal cell migration in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2005) 1.09
The Caenorhabditis elegans genes sqv-2 and sqv-6, which are required for vulval morphogenesis, encode glycosaminoglycan galactosyltransferase II and xylosyltransferase. J Biol Chem (2003) 1.08
RNA-ligand interactions: affinity and specificity of aminoglycoside dimers and acridine conjugates to the HIV-1 Rev response element. Biochemistry (2003) 1.08
Regulated translation of heparan sulfate N-acetylglucosamine N-deacetylase/n-sulfotransferase isozymes by structured 5'-untranslated regions and internal ribosome entry sites. J Biol Chem (2002) 1.07
Stable RAGE-heparan sulfate complexes are essential for signal transduction. ACS Chem Biol (2013) 1.07
CHO glycosylation mutants: proteoglycans. Methods Enzymol (2006) 1.06
Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney. Dev Biol (2004) 1.05
Fluorescence-based methods for evaluating the RNA affinity and specificity of HIV-1 Rev-RRE inhibitors. Biopolymers (2003) 1.05
Glycan antagonists and inhibitors: a fount for drug discovery. Crit Rev Biochem Mol Biol (2007) 1.05
Cell surface heparan sulfate is a receptor for attachment of envelope protein-free retrovirus-like particles and VSV-G pseudotyped MLV-derived retrovirus vectors to target cells. Mol Ther (2002) 1.05
Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber. Effect on tumor metastasis and neutrophil recruitment. J Biol Chem (2007) 1.04
Heparan sulfate Ndst1 gene function variably regulates multiple signaling pathways during mouse development. Dev Dyn (2007) 1.04
Human xylosyltransferase II is involved in the biosynthesis of the uniform tetrasaccharide linkage region in chondroitin sulfate and heparan sulfate proteoglycans. J Biol Chem (2006) 1.03
A highly fluorescent nucleoside analog based on thieno[3,4-d]pyrimidine senses mismatched pairing. Org Biomol Chem (2008) 1.03
Polarity of major grooves explored by using an isosteric emissive nucleoside. Chembiochem (2008) 1.02
A highly emissive fluorescent nucleoside that signals the activity of toxic ribosome-inactivating proteins. Angew Chem Int Ed Engl (2008) 1.02
Furan Decorated Nucleoside Analogues as Fluorescent Probes: synthesis, photophysical evaluation and site-specific incorporation. Tetrahedron (2007) 1.02
Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability. J Biol Chem (2010) 1.02
Deficiency of endothelial heparan sulfates attenuates allergic airway inflammation. J Immunol (2009) 1.00
Small changes in lymphocyte development and activation in mice through tissue-specific alteration of heparan sulphate. Immunology (2008) 0.99
On the electronic structure of ethidium. Chemistry (2005) 0.99
Heparan sulfate is essential for high mobility group protein 1 (HMGB1) signaling by the receptor for advanced glycation end products (RAGE). J Biol Chem (2011) 0.98
Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones. Bone (2011) 0.98
Altered heparan sulfate structure in mice with deleted NDST3 gene function. J Biol Chem (2008) 0.97
An emissive C analog distinguishes between G, 8-oxoG, and T. Org Lett (2009) 0.97
Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice. Blood (2012) 0.97
Deoxygenated disaccharide analogs as specific inhibitors of beta1-4-galactosyltransferase 1 and selectin-mediated tumor metastasis. J Biol Chem (2008) 0.96
Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites. Chem Commun (Camb) (2010) 0.96
Guanidinoneomycin B recognition of an HIV-1 RNA helix. Chembiochem (2008) 0.96
To D or not to D? On estimating the microenvironment polarity of biomolecular cavities. Org Biomol Chem (2007) 0.96
Glycosaminoglycan binding facilitates entry of a bacterial pathogen into central nervous systems. PLoS Pathog (2011) 0.96
Heparan sulfate proteoglycans and triglyceride-rich lipoprotein metabolism. Curr Opin Lipidol (2008) 0.95
Expression patterns of alpha 2,3-sialyltransferases and alpha 1,3-fucosyltransferases determine the mode of sialyl Lewis X inhibition by disaccharide decoys. J Biol Chem (2003) 0.95