Published in Proc Natl Acad Sci U S A on June 18, 2012
Interactions of the human telomere sequence with the nanocavity of the α-hemolysin ion channel reveal structure-dependent electrical signatures for hybrid folds. J Am Chem Soc (2013) 1.29
Single-molecule investigation of G-quadruplex folds of the human telomere sequence in a protein nanocavity. Proc Natl Acad Sci U S A (2014) 1.21
Individual RNA base recognition in immobilized oligonucleotides using a protein nanopore. Nano Lett (2012) 1.06
Recent trends in nanopores for biotechnology. Curr Opin Biotechnol (2012) 0.98
The evolution of nanopore sequencing. Front Genet (2015) 0.91
Programming nanopore ion flow for encoded multiplex microRNA detection. ACS Nano (2014) 0.89
Challenges in DNA motion control and sequence readout using nanopore devices. Nanotechnology (2015) 0.87
Effect of an Electrolyte Cation on Detecting DNA Damage with the Latch Constriction of α-Hemolysin. J Phys Chem Lett (2014) 0.87
Nanopore-based conformational analysis of a viral RNA drug target. ACS Nano (2014) 0.87
Nanopore detection of 8-oxoguanine in the human telomere repeat sequence. ACS Nano (2015) 0.86
Identification of DNA lesions using a third base pair for amplification and nanopore sequencing. Nat Commun (2015) 0.85
Electrical Current Signatures of DNA Base Modifications in Single Molecules Immobilized in the α-Hemolysin Ion Channel. Isr J Chem (2013) 0.85
Designing a polycationic probe for simultaneous enrichment and detection of microRNAs in a nanopore. ACS Nano (2013) 0.84
Modulation of the current signatures of DNA abasic site adducts in the α-hemolysin ion channel. Chem Commun (Camb) (2012) 0.83
Characterization of Interstrand DNA-DNA Cross-Links Using the α-Hemolysin Protein Nanopore. ACS Nano (2015) 0.83
Internal vs fishhook hairpin DNA: unzipping locations and mechanisms in the α-hemolysin nanopore. J Phys Chem B (2014) 0.82
Sequencing of DNA Lesions Facilitated by Site-Specific Excision via Base Excision Repair DNA Glycosylases Yielding Ligatable Gaps. J Am Chem Soc (2016) 0.81
Detection of benzo[a]pyrene-guanine adducts in single-stranded DNA using the α-hemolysin nanopore. Nanotechnology (2015) 0.80
DNA repair gene expression in biological tissues exposed to low-intensity infrared laser. Lasers Med Sci (2012) 0.79
A Fluorescent Probe to Measure DNA Damage and Repair. PLoS One (2015) 0.78
Quantitative detection of 8-Oxo-7,8-dihydro-2'-deoxyguanosine using chemical tagging and qPCR. Chem Res Toxicol (2014) 0.78
Designing DNA interstrand lock for locus-specific methylation detection in a nanopore. Sci Rep (2013) 0.77
Electrochemistry. Proc Natl Acad Sci U S A (2012) 0.77
Detecting DNA depurination with solid-state nanopores. PLoS One (2014) 0.77
Single-molecule detection of a guanine(C8) - thymine(N3) cross-link using ion channel recording. J Phys Org Chem (2014) 0.76
Single pyrimidine discrimination during voltage-driven translocation of osmylated oligodeoxynucleotides via the α-hemolysin nanopore. Beilstein J Nanotechnol (2016) 0.76
A stimuli-responsive nanopore based on a photoresponsive host-guest system. Sci Rep (2013) 0.76
Placement of oppositely charged aminoacids at a polypeptide termini determines the voltage-controlled braking of polymer transport through nanometer-scale pores. Sci Rep (2015) 0.76
Human Telomere G-Quadruplexes with Five Repeats Accommodate 8-Oxo-7,8-dihydroguanine by Looping out the DNA Damage. ACS Chem Biol (2015) 0.76
Kinetics of T3-DNA Ligase-Catalyzed Phosphodiester Bond Formation Measured Using the α-Hemolysin Nanopore. ACS Nano (2016) 0.75
Characterization of individual polynucleotide molecules using a membrane channel. Proc Natl Acad Sci U S A (1996) 18.77
Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore. Science (1996) 16.69
The potential and challenges of nanopore sequencing. Nat Biotechnol (2008) 14.24
Rapid nanopore discrimination between single polynucleotide molecules. Proc Natl Acad Sci U S A (2000) 8.35
Continuous base identification for single-molecule nanopore DNA sequencing. Nat Nanotechnol (2009) 8.09
Rapid discrimination among individual DNA hairpin molecules at single-nucleotide resolution using an ion channel. Nat Biotechnol (2001) 6.07
Automated forward and reverse ratcheting of DNA in a nanopore at 5-Å precision. Nat Biotechnol (2012) 5.71
Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase. Nat Biotechnol (2012) 4.16
Driven DNA transport into an asymmetric nanometer-scale pore. Phys Rev Lett (2000) 4.06
Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore. Proc Natl Acad Sci U S A (2009) 3.74
Characterization of nucleic acids by nanopore analysis. Acc Chem Res (2002) 3.52
Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae. DNA Repair (Amst) (2004) 2.71
The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA. Mutat Res (2001) 2.49
Processive replication of single DNA molecules in a nanopore catalyzed by phi29 DNA polymerase. J Am Chem Soc (2010) 2.36
Replication of individual DNA molecules under electronic control using a protein nanopore. Nat Nanotechnol (2010) 2.33
Enhanced translocation of single DNA molecules through alpha-hemolysin nanopores by manipulation of internal charge. Proc Natl Acad Sci U S A (2008) 2.11
Identification of epigenetic DNA modifications with a protein nanopore. Chem Commun (Camb) (2010) 1.93
An overview of chemical processes that damage cellular DNA: spontaneous hydrolysis, alkylation, and reactions with radicals. Chem Res Toxicol (2009) 1.85
Nucleotide identification and orientation discrimination of DNA homopolymers immobilized in a protein nanopore. Nano Lett (2008) 1.81
A method for detecting abasic sites in living cells: age-dependent changes in base excision repair. Proc Natl Acad Sci U S A (2000) 1.67
Mapping the position of DNA polymerase-bound DNA templates in a nanopore at 5 A resolution. ACS Nano (2009) 1.62
A primary hydrogen-deuterium isotope effect observed at the single-molecule level. Nat Chem (2010) 1.58
A novel, sensitive, and specific assay for abasic sites, the most commonly produced DNA lesion. Biochemistry (1992) 1.51
Chemical tags facilitate the sensing of individual DNA strands with nanopores. Angew Chem Int Ed Engl (2008) 1.47
Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes. Nano Lett (2011) 1.42
Simple fluorescent pyrimidine analogues detect the presence of DNA abasic sites. J Am Chem Soc (2005) 1.42
Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores. Proc Natl Acad Sci U S A (2010) 1.41
Nanopore detection of 8-oxo-7,8-dihydro-2'-deoxyguanosine in immobilized single-stranded DNA via adduct formation to the DNA damage site. J Am Chem Soc (2010) 1.39
High-performance liquid chromatography--tandem mass spectrometry measurement of radiation-induced base damage to isolated and cellular DNA. Chem Res Toxicol (2000) 1.39
Spectrum of complex DNA damages depends on the incident radiation. Radiat Res (2006) 1.17
Controlling the translocation of single-stranded DNA through alpha-hemolysin ion channels using viscosity. Langmuir (2009) 1.11
Urea facilitates the translocation of single-stranded DNA and RNA through the alpha-hemolysin nanopore. Biophys J (2010) 1.08
Sequence-specific single-molecule analysis of 8-oxo-7,8-dihydroguanine lesions in DNA based on unzipping kinetics of complementary probes in ion channel recordings. J Am Chem Soc (2011) 1.01
DNA translocation and unzipping through a nanopore: some geometrical effects. Biophys J (2010) 1.00
Abasic sites and strand breaks in DNA cause transcriptional mutagenesis in Escherichia coli. Proc Natl Acad Sci U S A (2010) 0.98
Targeting abasic sites and single base bulges in DNA with metalloinsertors. J Am Chem Soc (2008) 0.95
DNA analysis by dynamic chemistry. Angew Chem Int Ed Engl (2010) 0.91
Emergence of symmetry and chirality in crown ether complexes with alkali metal cations. J Phys Chem A (2010) 0.87
Direct detection and quantification of abasic sites for in vivo studies of DNA damage and repair. Nucl Med Biol (2009) 0.87
Construction of highly reactive probes for abasic site detection by introduction of an aromatic and a guanidine residue into an aminooxy group. J Am Chem Soc (2009) 0.83
Detection of abasic sites on individual DNA molecules using atomic force microscopy. Anal Chem (2001) 0.80
Single ion-channel recordings using glass nanopore membranes. J Am Chem Soc (2007) 2.22
The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo. Biochemistry (2003) 1.92
Unzipping kinetics of duplex DNA containing oxidized lesions in an α-hemolysin nanopore. J Am Chem Soc (2012) 1.80
Three-dimensional battery architectures. Chem Rev (2004) 1.75
Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1. Biochemistry (2008) 1.62
The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo. Proc Natl Acad Sci U S A (2010) 1.61
In vitro nucleotide misinsertion opposite the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin and DNA synthesis past the lesions using Escherichia coli DNA polymerase I (Klenow fragment). Biochemistry (2002) 1.60
Diffusional motion of a particle translocating through a nanopore. ACS Nano (2012) 1.53
Bench-top method for fabricating glass-sealed nanodisk electrodes, glass nanopore electrodes, and glass nanopore membranes of controlled size. Anal Chem (2007) 1.49
Formation of 13C-, 15N-, and 18O-labeled guanidinohydantoin from guanosine oxidation with singlet oxygen. Implications for structure and mechanism. J Am Chem Soc (2003) 1.42
Nanopore detection of 8-oxo-7,8-dihydro-2'-deoxyguanosine in immobilized single-stranded DNA via adduct formation to the DNA damage site. J Am Chem Soc (2010) 1.39
Interactions of the human telomere sequence with the nanocavity of the α-hemolysin ion channel reveal structure-dependent electrical signatures for hybrid folds. J Am Chem Soc (2013) 1.29
Monitoring the escape of DNA from a nanopore using an alternating current signal. J Am Chem Soc (2010) 1.23
Recognition and removal of oxidized guanines in duplex DNA by the base excision repair enzymes hOGG1, yOGG1, and yOGG2. Biochemistry (2003) 1.21
Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts. Biochemistry (2010) 1.18
Effect of the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin on proofreading by Escherichia coli DNA polymerase I (Klenow fragment) in different sequence contexts. Biochemistry (2003) 1.17
Ionic conductivity of the aqueous layer separating a lipid bilayer membrane and a glass support. Langmuir (2006) 1.15
Controlling the translocation of single-stranded DNA through alpha-hemolysin ion channels using viscosity. Langmuir (2009) 1.11
Electrostatic-gated transport in chemically modified glass nanopore electrodes. J Am Chem Soc (2006) 1.10
The nanopore electrode. Anal Chem (2004) 1.10
A new family of multiferrocene complexes with enhanced control of structure and stoichiometry via coordination-driven self-assembly and their electrochemistry. J Am Chem Soc (2008) 1.09
Nanoparticle transport in conical-shaped nanopores. Anal Chem (2011) 1.07
DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts. J Am Chem Soc (2008) 1.07
Influence of asymmetric donor-receiver ion concentration upon transscleral iontophoretic transport. J Pharm Sci (2005) 1.07
Chemical modification of siRNA bases to probe and enhance RNA interference. J Org Chem (2011) 1.06
Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context. J Biol Chem (2013) 1.05
Electrophoretic capture and detection of nanoparticles at the opening of a membrane pore using scanning electrochemical microscopy. Anal Chem (2004) 1.05
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia. Proc Natl Acad Sci U S A (2011) 1.04
Spermine participates in oxidative damage of guanosine and 8-oxoguanosine leading to deoxyribosylurea formation. J Am Chem Soc (2004) 1.02
Alternating current impedance imaging of membrane pores using scanning electrochemical microscopy. Anal Chem (2005) 1.01
Sequence-specific single-molecule analysis of 8-oxo-7,8-dihydroguanine lesions in DNA based on unzipping kinetics of complementary probes in ion channel recordings. J Am Chem Soc (2011) 1.01
G-quadruplex folds of the human telomere sequence alter the site reactivity and reaction pathway of guanine oxidation compared to duplex DNA. Chem Res Toxicol (2013) 1.01
Human endonuclease VIII-like (NEIL) proteins in the giant DNA Mimivirus. DNA Repair (Amst) (2007) 1.00
Structural context effects in the oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine to hydantoin products: electrostatics, base stacking, and base pairing. J Am Chem Soc (2012) 0.99
Sensitivity and signal complexity as a function of the number of ion channels in a stochastic sensor. Anal Chem (2009) 0.99
Base-excision repair activity of uracil-DNA glycosylase monitored using the latch zone of α-hemolysin. J Am Chem Soc (2013) 0.98
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin. Biochemistry (2010) 0.97
Reconciliation of chemical, enzymatic, spectroscopic and computational data to assign the absolute configuration of the DNA base lesion spiroiminodihydantoin. J Am Chem Soc (2013) 0.97
Characterization of 2'-deoxyguanosine oxidation products observed in the Fenton-like system Cu(II)/H2O2/reductant in nucleoside and oligodeoxynucleotide contexts. Org Biomol Chem (2011) 0.96
Magnetic field-controlled microfluidic transport. J Am Chem Soc (2002) 0.95
Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoin. DNA Repair (Amst) (2013) 0.94
The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts. DNA Repair (Amst) (2009) 0.93
Photon gated transport at the glass nanopore electrode. J Am Chem Soc (2006) 0.93
Construction of multifunctional cuboctahedra via coordination-driven self-assembly. J Am Chem Soc (2009) 0.93
Pressure-dependent ion current rectification in conical-shaped glass nanopores. J Am Chem Soc (2011) 0.93
Glass nanopore-based ion-selective electrodes. Anal Chem (2007) 0.92
An exploration of mechanisms for the transformation of 8-oxoguanine to guanidinohydantoin and spiroiminodihydantoin by density functional theory. J Am Chem Soc (2008) 0.92
Quartz nanopore membranes for suspended bilayer ion channel recordings. Anal Chem (2010) 0.91
Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases. DNA Repair (Amst) (2009) 0.91
Steady-state voltammetric response of the nanopore electrode. Anal Chem (2006) 0.91
Structural destabilization of DNA duplexes containing single-base lesions investigated by nanopore measurements. Biochemistry (2013) 0.91
Simultaneous alternating and direct current readout of protein ion channel blocking events using glass nanopore membranes. Anal Chem (2008) 0.91
Observation of redox-induced electron transfer and spin crossover for dinuclear cobalt and iron complexes with the 2,5-di-tert-butyl-3,6-dihydroxy-1,4-benzoquinonate bridging ligand. J Am Chem Soc (2009) 0.91
Synthesis of a new family of hexakisferrocenyl hexagons and their electrochemical behavior. J Org Chem (2008) 0.90
Unusual structural features of hydantoin lesions translate into efficient recognition by Escherichia coli Fpg. Biochemistry (2007) 0.90
Oxidatively induced DNA-protein cross-linking between single-stranded binding protein and oligodeoxynucleotides containing 8-oxo-7,8-dihydro-2'-deoxyguanosine. Biochemistry (2005) 0.90
Mechanism of two-electron oxidation of deoxyguanosine 5'-monophosphate by a platinum(IV) complex. J Am Chem Soc (2004) 0.89
Comparison of Transition Metal-Mediated Oxidation Reactions of Guanine in Nucleoside and Single-Stranded Oligodeoxynucleotide Contexts. Inorganica Chim Acta (2011) 0.88
Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair. J Am Chem Soc (2013) 0.87
Crystal structure of DNA polymerase β with DNA containing the base lesion spiroiminodihydantoin in a templating position. Biochemistry (2014) 0.87
In vitro ligation of oligodeoxynucleotides containing C8-oxidized purine lesions using bacteriophage T4 DNA ligase. Biochemistry (2007) 0.86
Whence flavins? Redox-active ribonucleotides link metabolism and genome repair to the RNA world. Acc Chem Res (2012) 0.86
Strong effects of cluster size and air exposure on oxygen reduction and carbon oxidation electrocatalysis by size-selected Pt(n) (n ≤ 11) on glassy carbon electrodes. J Am Chem Soc (2013) 0.85
A prebiotic role for 8-oxoguanosine as a flavin mimic in pyrimidine dimer photorepair. J Am Chem Soc (2011) 0.85
Electrical Current Signatures of DNA Base Modifications in Single Molecules Immobilized in the α-Hemolysin Ion Channel. Isr J Chem (2013) 0.85
Exploration of mechanisms for the transformation of 8-hydroxy guanine radical to FAPyG by density functional theory. Chem Res Toxicol (2007) 0.84
Fluorescence microscopy of the pressure-dependent structure of lipid bilayers suspended across conical nanopores. J Am Chem Soc (2011) 0.84
8-Oxoguanosine switches modulate the activity of alkylated siRNAs by controlling steric effects in the major versus minor grooves. J Am Chem Soc (2011) 0.84
pH- and ionic strength-controlled cation permselectivity in amine-modified nanoporous opal films. Langmuir (2006) 0.84
Electroosmotic pore transport in human skin. Pharm Res (2003) 0.84
Modulation of the current signatures of DNA abasic site adducts in the α-hemolysin ion channel. Chem Commun (Camb) (2012) 0.83
Electronic structure of DNA--unique properties of 8-oxoguanosine. J Am Chem Soc (2009) 0.83
Internal vs fishhook hairpin DNA: unzipping locations and mechanisms in the α-hemolysin nanopore. J Phys Chem B (2014) 0.82
Electrochemistry of nanopore electrodes in low ionic strength solutions. J Phys Chem B (2006) 0.82
Diffusive-convective transport into a porous membrane. A comparison of theory and experiment using scanning electrochemical microscopy operated in reverse imaging mode. Anal Chem (2002) 0.82
Zeptomole voltammetric detection and electron-transfer rate measurements using platinum electrodes of nanometer dimensions. Anal Chem (2003) 0.81