Published in J Immunol on August 15, 2005
Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev (2010) 2.68
Heme oxygenase-1/carbon monoxide: from metabolism to molecular therapy. Am J Respir Cell Mol Biol (2009) 1.94
Carbon monoxide and bilirubin: potential therapies for pulmonary/vascular injury and disease. Am J Respir Cell Mol Biol (2006) 1.65
The p38 mitogen-activated protein kinase (MAPK) pathway in rheumatoid arthritis. Ann Rheum Dis (2007) 1.63
The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages. J Immunol (2007) 1.43
Role of carbon monoxide in cardiovascular function. J Cell Mol Med (2006) 1.41
Heme oxygenase in the regulation of vascular biology: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal (2010) 1.41
Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease. Free Radic Biol Med (2009) 1.38
Heat shock response and acute lung injury. Free Radic Biol Med (2006) 1.29
Carbon monoxide protects against ventilator-induced lung injury via PPAR-gamma and inhibition of Egr-1. Am J Respir Crit Care Med (2008) 1.23
The p38 mitogen-activated protein kinase pathway--a potential target for intervention in infarction, hypertrophy, and heart failure. J Mol Cell Cardiol (2010) 1.22
The carbon monoxide-releasing molecule CORM-2 inhibits the inflammatory response induced by cytokines in Caco-2 cells. Br J Pharmacol (2007) 1.13
Bench-to-bedside review: Carbon monoxide--from mitochondrial poisoning to therapeutic use. Crit Care (2009) 1.08
Heat stress upregulates chaperone heat shock protein 70 and antioxidant manganese superoxide dismutase through reactive oxygen species (ROS), p38MAPK, and Akt. Cell Stress Chaperones (2009) 1.02
Heme Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock. J Clin Biochem Nutr (2008) 1.01
Therapeutic approach to neurodegenerative diseases by medical gases: focusing on redox signaling and related antioxidant enzymes. Oxid Med Cell Longev (2012) 0.98
Transcriptome analysis of human cancer reveals a functional role of heme oxygenase-1 in tumor cell adhesion. Mol Cancer (2010) 0.96
Carbon monoxide: present and future indications for a medical gas. Korean J Intern Med (2013) 0.95
Carbon monoxide induces hypothermia tolerance in Kupffer cells and attenuates liver ischemia/reperfusion injury in rats. Liver Transpl (2011) 0.93
Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation. Transl Res (2015) 0.90
Regulation of ROS production and vascular function by carbon monoxide. Oxid Med Cell Longev (2012) 0.87
Arsenite stabilizes HIF-1α protein through p85α-mediated up-regulation of inducible Hsp70 protein expression. Cell Mol Life Sci (2010) 0.87
Review article: carbon monoxide in gastrointestinal physiology and its potential in therapeutics. Aliment Pharmacol Ther (2013) 0.85
Protective effect of carbon monoxide pre-conditioning on LPS-induced endothelial cell stress. Cell Stress Chaperones (2009) 0.85
Postconditioning with inhaled carbon monoxide counteracts apoptosis and neuroinflammation in the ischemic rat retina. PLoS One (2012) 0.85
Core temperature correlates with expression of selected stress and immunomodulatory genes in febrile patients with sepsis and noninfectious SIRS. Cell Stress Chaperones (2009) 0.85
Mesothelioma cells escape heat stress by upregulating Hsp40/Hsp70 expression via mitogen-activated protein kinases. J Biomed Biotechnol (2009) 0.85
Deficiency in p38β MAPK fails to inhibit cytokine production or protect neurons against inflammatory insult in in vitro and in vivo mouse models. PLoS One (2013) 0.84
Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo. J Nat Prod (2012) 0.83
Role of carbon monoxide in kidney function: is a little carbon monoxide good for the kidney? Curr Pharm Biotechnol (2012) 0.83
Inducible hsp70 in the regulation of cancer cell survival: analysis of chaperone induction, expression and activity. Cancers (Basel) (2011) 0.83
Beneficial effect of prolonged heme oxygenase 1 activation in a rat model of chronic heart failure. Dis Model Mech (2013) 0.82
Zinc Supplementation with Polaprezinc Protects Mouse Hepatocytes against Acetaminophen-Induced Toxicity via Induction of Heat Shock Protein 70. J Clin Biochem Nutr (2009) 0.82
Heme Oxygenase-1 and Carbon Monoxide in the Heart: The Balancing Act Between Danger Signaling and Pro-Survival. Circ Res (2016) 0.82
Heme Oxygenases in Cardiovascular Health and Disease. Physiol Rev (2016) 0.82
Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia. Am J Physiol Lung Cell Mol Physiol (2015) 0.79
Biliverdin protects against liver ischemia reperfusion injury in swine. PLoS One (2013) 0.79
Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. Toxicol Appl Pharmacol (2011) 0.78
Hyperthermia promotes and prevents respiratory epithelial apoptosis through distinct mechanisms. Am J Respir Cell Mol Biol (2012) 0.78
Alterations in molecular chaperones and eIF2alpha during lung endothelial cell apoptosis. Am J Physiol Lung Cell Mol Physiol (2010) 0.75
Comparative proteomic analysis of liver antioxidant mechanisms in Megalobrama amblycephala stimulated with dietary emodin. Sci Rep (2017) 0.75
Anesthesia-Related Carbon Monoxide Exposure: Toxicity and Potential Therapy. Anesth Analg (2016) 0.75
Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis. PLoS One (2010) 0.75
Carbon monoxide and anesthesia-induced neurotoxicity. Neurotoxicol Teratol (2016) 0.75
IL-32γ delays spontaneous apoptosis of human neutrophils through MCL-1, regulated primarily by the p38 MAPK pathway. PLoS One (2014) 0.75
Growth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive grasping. BMC Musculoskelet Disord (2016) 0.75
Isolated heart model demonstrates evidence of contractile and diastolic dysfunction in right ventricles from rats with sugen/hypoxia-induced pulmonary hypertension. Physiol Rep (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol (2010) 9.02
Autophagy in human health and disease. N Engl J Med (2013) 8.71
Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev (2006) 7.76
Delamanid for multidrug-resistant pulmonary tuberculosis. N Engl J Med (2012) 6.73
Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. Cell (2007) 3.54
Mechanisms of cell death in oxidative stress. Antioxid Redox Signal (2007) 3.33
Mucosal biofilm formation on middle-ear mucosa in the chinchilla model of otitis media. JAMA (2002) 2.96
Inflammasome-regulated cytokines are critical mediators of acute lung injury. Am J Respir Crit Care Med (2012) 2.92
Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis. J Exp Med (2006) 2.92
Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. J Exp Med (2006) 2.77
Autophagy in human health and disease. N Engl J Med (2013) 2.73
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One (2008) 2.67
Effect of Early Intervention on Long-Term Outcomes of Critically Ill Cancer Patients Admitted to ICUs. Crit Care Med (2015) 2.66
Inhaled carbon monoxide confers antiinflammatory effects against ventilator-induced lung injury. Am J Respir Crit Care Med (2004) 2.60
Lack of Fas antagonism by Met in human fatty liver disease. Nat Med (2007) 2.48
Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A (2004) 2.42
Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. Autophagy (2008) 2.38
Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner. J Biol Chem (2009) 2.33
An integrated clinico-metabolomic model improves prediction of death in sepsis. Sci Transl Med (2013) 2.23
Performances of prognostic scoring systems in patients with healthcare-associated pneumonia. Clin Infect Dis (2012) 2.23
Blood pressure control for diabetic retinopathy. Cochrane Database Syst Rev (2015) 2.19
Validity and feasibility of the american college of surgeons colectomy composite outcome quality measure. Ann Surg (2013) 2.18
Treatment outcomes for HIV-uninfected patients with multidrug-resistant and extensively drug-resistant tuberculosis. Clin Infect Dis (2008) 2.17
Endobronchial ultrasound versus mediastinoscopy for mediastinal nodal staging of non-small-cell lung cancer. J Thorac Oncol (2015) 2.17
Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance. Mol Cell Biochem (2002) 2.16
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury. Nat Med (2003) 2.15
The influence of resident involvement on surgical outcomes. J Am Coll Surg (2011) 2.12
Heme oxygenase-1: the "emerging molecule" has arrived. Am J Respir Cell Mol Biol (2002) 2.12
A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints. J Biol Chem (2007) 2.09
Estrogen regulation of duodenal bicarbonate secretion and sex-specific protection of human duodenum. Gastroenterology (2011) 2.07
Autophagy is an adaptive response in desmin-related cardiomyopathy. Proc Natl Acad Sci U S A (2008) 2.07
Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes. Cancer Res (2002) 2.05
CO as a cellular signaling molecule. Annu Rev Pharmacol Toxicol (2006) 2.03
Viral pneumonias in adults: radiologic and pathologic findings. Radiographics (2002) 2.02
Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study. Crit Care (2012) 2.02
Inhaled hydrogen sulfide protects against ventilator-induced lung injury. Anesthesiology (2010) 2.02
Heme oxygenase-1/carbon monoxide: from metabolism to molecular therapy. Am J Respir Cell Mol Biol (2009) 1.94
Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension. Am J Respir Crit Care Med (2010) 1.93
Optimizing ACS NSQIP modeling for evaluation of surgical quality and risk: patient risk adjustment, procedure mix adjustment, shrinkage adjustment, and surgical focus. J Am Coll Surg (2013) 1.84
Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1. J Biol Chem (2003) 1.83
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proc Natl Acad Sci U S A (2010) 1.82
Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor. Genes Dev (2008) 1.78
Clinical characteristics and efficacy of bronchoscopic intervention for tracheobronchial leiomyoma. Respirology (2008) 1.76
Brief inhalation of low-dose carbon monoxide protects rodents and swine from postoperative ileus. Crit Care Med (2005) 1.73
Involvement of reductive stress in the cardiomyopathy in transgenic mice with cardiac-specific overexpression of heat shock protein 27. Hypertension (2010) 1.73
Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death. Am J Respir Cell Mol Biol (2006) 1.69
Carbon monoxide prevents ventilator-induced lung injury via caveolin-1. Crit Care Med (2009) 1.68
The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1. J Immunol (2009) 1.66
Carbon monoxide and bilirubin: potential therapies for pulmonary/vascular injury and disease. Am J Respir Cell Mol Biol (2006) 1.65
Induction of heat shock proteins by heregulin beta1 leads to protection from apoptosis and anchorage-independent growth. Oncogene (2005) 1.64
Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation. Genes Dev (2003) 1.61
Hepatitis C virus infection and hepatotoxicity during antituberculosis chemotherapy. Chest (2007) 1.60
Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine. Gastroenterology (2003) 1.59
Heat shock factor 1 and heat shock proteins: critical partners in protection against acute cell injury. Crit Care Med (2002) 1.58
Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation. Circulation (2009) 1.58
Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage. EMBO J (2002) 1.58
Methodological reporting quality of randomized controlled trials in three spine journals from 2010 to 2012. Eur Spine J (2014) 1.55
Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathways. J Mol Cell Cardiol (2010) 1.54
Caveolae compartmentalization of heme oxygenase-1 in endothelial cells. FASEB J (2004) 1.54
Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation. J Biol Chem (2006) 1.53
Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3. J Biol Chem (2002) 1.52
Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet (2009) 1.52
Serum cytokines and critical illness-related corticosteroid insufficiency. Intensive Care Med (2010) 1.51
Caveolin-1 confers antiinflammatory effects in murine macrophages via the MKK3/p38 MAPK pathway. Am J Respir Cell Mol Biol (2005) 1.51
Costs of congenital diaphragmatic hernia repair in the United States-extracorporeal membrane oxygenation foots the bill. J Pediatr Surg (2011) 1.50
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells. Proc Natl Acad Sci U S A (2014) 1.50
Heme oxygenase-1: redox regulation of a stress protein in lung and cell culture models. Antioxid Redox Signal (2005) 1.49
Thioredoxin catalyzes the denitrosation of low-molecular mass and protein S-nitrosothiols. Biochemistry (2007) 1.49
Genetically encoded fluorescent sensors for intracellular NADH detection. Cell Metab (2011) 1.47
Heme oxygenase-1: from bench to bedside. Am J Respir Crit Care Med (2005) 1.47
Pulmonary nocardiosis with multiple cavitary nodules in a HIV-negative immunocompromised patient. Intern Med (2004) 1.47
Malfolded protein structure and proteostasis in lung diseases. Am J Respir Crit Care Med (2014) 1.47
Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury. Am J Pathol (2003) 1.47
Gene expression profiling of target genes in ventilator-induced lung injury. Physiol Genomics (2006) 1.45
Outcome and predictors of mortality in patients requiring invasive mechanical ventilation due to acute respiratory failure while undergoing ambulatory chemotherapy for solid cancers. Support Care Cancer (2013) 1.44
Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects. Am J Pathol (2003) 1.43
Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP. Hum Mol Genet (2011) 1.42
Protective functions of heme oxygenase-1 and carbon monoxide in the respiratory system. Antioxid Redox Signal (2007) 1.41