Published in Am J Physiol Endocrinol Metab on August 09, 2005
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants. Nat Genet (2014) 2.38
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Fatty acid signaling in the beta-cell and insulin secretion. Diabetes (2006) 2.22
Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor. Diabetes (2003) 2.16
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Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise. J Biol Chem (2002) 2.11
Role for activating transcription factor 3 in stress-induced beta-cell apoptosis. Mol Cell Biol (2004) 2.10
Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family. J Lipid Res (2004) 2.08
Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms. Cell Metab (2008) 1.99
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Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function. Endocrinology (2009) 1.71
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Saturated fatty acid-induced apoptosis in MDA-MB-231 breast cancer cells. A role for cardiolipin. J Biol Chem (2003) 1.61
Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. Proc Natl Acad Sci U S A (2005) 1.59
Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes. J Clin Invest (2011) 1.55
Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets. Diabetes (2009) 1.51
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AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats. Am J Physiol Endocrinol Metab (2005) 1.51
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Anti-diabetic properties of the Canadian lowbush blueberry Vaccinium angustifolium Ait. Phytomedicine (2006) 1.44
A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. Diabetes (2004) 1.43
Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells. Am J Physiol Endocrinol Metab (2005) 1.43
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Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nat Genet (2003) 1.40
Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation. J Biol Chem (2004) 1.39
The Lip lipoprotein from Neisseria gonorrhoeae stimulates cytokine release and NF-kappaB activation in epithelial cells in a Toll-like receptor 2-dependent manner. J Biol Chem (2003) 1.35
SLC1 and SLC4 encode partially redundant acyl-coenzyme A 1-acylglycerol-3-phosphate O-acyltransferases of budding yeast. J Biol Chem (2007) 1.33
Mitochondrial dysfunction is involved in apoptosis induced by serum withdrawal and fatty acids in the beta-cell line INS-1. Endocrinology (2003) 1.32
Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1. Diabetes (2004) 1.29
Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci (2012) 1.29
A role for hypothalamic malonyl-CoA in the control of food intake. J Biol Chem (2005) 1.28
Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion. J Biol Chem (2009) 1.27
The islet beta-cell: fuel responsive and vulnerable. Trends Endocrinol Metab (2008) 1.27
Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (2009) 1.26
High glucose disrupts mitochondrial morphology in retinal endothelial cells: implications for diabetic retinopathy. Am J Pathol (2010) 1.24
Evolution of the acyl-CoA binding protein (ACBP). Biochem J (2005) 1.23
Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance. Diabetes (2006) 1.22
A role for interferon-gamma in focal cerebral ischemia in mice. J Neuropathol Exp Neurol (2004) 1.21
Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25. Cell Metab (2010) 1.18
Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. EMBO J (2014) 1.18
Metabolic partitioning of endogenous fatty acid in adipocytes. Obes Res (2003) 1.17
Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart. Am J Physiol Endocrinol Metab (2005) 1.17
Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation. Gastroenterology (2007) 1.17
MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity. J Clin Invest (2012) 1.17
Impact of D2 receptor internalization on binding affinity of neuroimaging radiotracers. Neuropsychopharmacology (2009) 1.15
Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes. Mol Cell Endocrinol (2008) 1.12
Alpha-synuclein gene deletion decreases brain palmitate uptake and alters the palmitate metabolism in the absence of alpha-synuclein palmitate binding. Biochemistry (2005) 1.11
Vectorial acylation in Saccharomyces cerevisiae. Fat1p and fatty acyl-CoA synthetase are interacting components of a fatty acid import complex. J Biol Chem (2003) 1.11
Alpha-synuclein gene ablation increases docosahexaenoic acid incorporation and turnover in brain phospholipids. J Neurochem (2007) 1.11
Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes. Diabetologia (2013) 1.11
Lipid-binding proteins and lipoprotein lipase activity in human skeletal muscle: influence of physical activity and gender. J Appl Physiol (1985) (2004) 1.11
The diagnostic value of PET/CT scanning in patients with cervical cancer: a prospective study. Gynecol Oncol (2007) 1.10
Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases. FASEB J (2008) 1.10
Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation. Endocrinology (2004) 1.10
Glucose-dependent insulinotropic polypeptide modulates adipocyte lipolysis and reesterification. Obesity (Silver Spring) (2006) 1.09
Vitamin D status and its predictive factors in pregnancy in 2 Australian populations. Aust N Z J Obstet Gynaecol (2011) 1.09
Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose. Biochem J (2007) 1.08
CD40 ligand binds to alpha5beta1 integrin and triggers cell signaling. J Biol Chem (2006) 1.08
Temporal profiling of the secretome during adipogenesis in humans. J Proteome Res (2010) 1.07
Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40. J Biol Chem (2005) 1.06
Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation. Diabetes (2002) 1.05
Lipotoxicity: why do saturated fatty acids cause and monounsaturates protect against it? J Gastroenterol Hepatol (2009) 1.05
A pentadecapeptide fragment of islet neogenesis-associated protein increases beta-cell mass and reverses diabetes in C57BL/6J mice. Ann Surg (2004) 1.05
AMPK exerts dual regulatory effects on the PI3K pathway. J Mol Signal (2010) 1.05
A large randomized placebo controlled study of auricular acupuncture for alcohol dependence. J Subst Abuse Treat (2002) 1.05
Mechanism of cellular uptake of long-chain fatty acids: Do we need cellular proteins? Mol Cell Biochem (2002) 1.04
Adaptive failure to high-fat diet characterizes steatohepatitis in Alms1 mutant mice. Biochem Biophys Res Commun (2006) 1.04
The L-type voltage-gated Ca2+ channel is the Ca2+ sensor protein of stimulus-secretion coupling in pancreatic beta cells. Biochemistry (2007) 1.03