Published in Exp Biol Med (Maywood) on February 01, 2005
Radiation protection following nuclear power accidents: a survey of putative mechanisms involved in the radioprotective actions of taurine during and after radiation exposure. Microb Ecol Health Dis (2012) 1.39
Reactive oxygen species in the regulation of synaptic plasticity and memory. Antioxid Redox Signal (2010) 1.37
Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia. Stroke (2008) 1.25
Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats. J Pineal Res (2007) 1.11
Antiinflammatory activity of melatonin in central nervous system. Curr Neuropharmacol (2010) 1.09
Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway. Nutr Metab (Lond) (2013) 1.02
Melatonin in Alzheimer's disease and other neurodegenerative disorders. Behav Brain Funct (2006) 1.01
Dual effects of melatonin on oxidative stress after surgical brain injury in rats. J Pineal Res (2008) 0.90
Melatonin combats molecular terrorism at the mitochondrial level. Interdiscip Toxicol (2008) 0.90
Neuroimmune endocrine effects of antidepressants. Neuropsychiatr Dis Treat (2012) 0.86
Methylene Blue promotes cortical neurogenesis and ameliorates behavioral deficit after photothrombotic stroke in rats. Neuroscience (2016) 0.84
Radioprotective effect of melatonin on the cervical spinal cord in irradiated rats. Cell J (2013) 0.83
Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation. Oncotarget (2015) 0.83
Melatonin ameliorates injury and specific responses of ischemic striatal neurons in rats. J Histochem Cytochem (2013) 0.80
Melatonin-based therapeutics for neuroprotection in stroke. Int J Mol Sci (2013) 0.79
Time-of-day determines neuronal damage and mortality after cardiac arrest. Neurobiol Dis (2009) 0.79
Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats. Biores Open Access (2015) 0.78
Effects of melatonin in experimental stroke models in acute, sub-acute, and chronic stages. Neuropsychiatr Dis Treat (2009) 0.77
Pinealectomy stimulates and exogenous melatonin inhibits harmful effects of epileptiform activity during pregnancy in the hippocampus of newborn rats: an immunohistochemical study. Childs Nerv Syst (2005) 0.76
The role of melatonin in the pathogenesis of multiple sclerosis: a case-control study. Int J Prev Med (2013) 0.76
Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action. Br J Pharmacol (2015) 0.76
Dietary Sources and Bioactivities of Melatonin. Nutrients (2017) 0.75
Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice. Redox Biol (2017) 0.75
The effect of melaxen on the activity of caspases and the glutathione antioxidant system in toxic liver injury. Acta Naturae (2014) 0.75
New Prophylactic and Therapeutic Strategies for Spinal Cord Injury. J Lifestyle Med (2013) 0.75
Serum paraoxonase 1 activity and oxidative stress in pediatric patients with pulmonary tuberculosis. Med Princ Pract (2014) 1.99
Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms. Brain (2009) 1.89
VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena. Brain (2004) 1.67
The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. FASEB J (2006) 1.64
TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration. Neurobiol Dis (2008) 1.52
Melatonin: a multitasking molecule. Prog Brain Res (2010) 1.46
Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and STAT-1. Neurobiol Dis (2005) 1.45
Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. FASEB J (2005) 1.40
Neural stem/precursor cells for the treatment of ischemic stroke. J Neurol Sci (2007) 1.31
Extrapineal melatonin: sources, regulation, and potential functions. Cell Mol Life Sci (2014) 1.31
Human vascular endothelial growth factor protects axotomized retinal ganglion cells in vivo by activating ERK-1/2 and Akt pathways. J Neurosci (2006) 1.31
Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans. Acta Biochim Pol (2003) 1.30
Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticity. Brain (2011) 1.29
Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J Pineal Res (2009) 1.29
Melatonin and the ovary: physiological and pathophysiological implications. Fertil Steril (2008) 1.29
Melatonin mitigates mitochondrial malfunction. J Pineal Res (2005) 1.27
Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2. FASEB J (2004) 1.25
Melatonin as a radioprotective agent: a review. Int J Radiat Oncol Biol Phys (2004) 1.25
Ovarian cancer during pregnancy: analysis of 15 cases. Gynecol Oncol (2007) 1.23
Melatonin: reducing the toxicity and increasing the efficacy of drugs. J Pharm Pharmacol (2002) 1.23
Melatonin and mitochondrial function. Life Sci (2004) 1.20
Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review. J Pineal Res (2014) 1.20
Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling. J Pineal Res (2011) 1.20
Melatonin and pregnancy in the human. Reprod Toxicol (2008) 1.17
Melatonin: a novel protective agent against oxidative injury of the ischemic/reperfused heart. Cardiovasc Res (2003) 1.15
Melatonin and reproduction revisited. Biol Reprod (2009) 1.14
Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages. J Neuroimmunol (2005) 1.14
Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia. Nat Neurosci (2006) 1.10
Cardiovascular diseases: protective effects of melatonin. J Pineal Res (2008) 1.10
Phytomelatonin: a review. J Exp Bot (2008) 1.09
c-Jun N-terminal kinase 2 deficiency protects against hypercholesterolemia-induced endothelial dysfunction and oxidative stress. Circulation (2008) 1.08
Melatonin and its potential biological functions in the fruits of sweet cherry. J Pineal Res (2013) 1.07
Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1. FASEB J (2003) 1.07
Inhibition of neuronal apoptosis in vitro and in vivo using TAT-mediated protein transduction. Mol Cell Neurosci (2002) 1.06
Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice. J Pineal Res (2005) 1.06
Role of Nogo-A in neuronal survival in the reperfused ischemic brain. J Cereb Blood Flow Metab (2010) 1.06
Light at night, chronodisruption, melatonin suppression, and cancer risk: a review. Crit Rev Oncog (2007) 1.05
Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice. J Pineal Res (2008) 1.05
Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain. Acta Neuropathol (2011) 1.04
Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice. Stroke (2003) 1.04
Melatonin as an antioxidant: physiology versus pharmacology. J Pineal Res (2005) 1.03
Melatonin: an established antioxidant worthy of use in clinical trials. Mol Med (2008) 1.03
Role of melatonin in metabolic regulation. Rev Endocr Metab Disord (2009) 1.03
Brain-derived neurotrophic factor, stress and depression: a minireview. Brain Res Bull (2008) 1.02
Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway. Nutr Metab (Lond) (2013) 1.02
Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction. Redox Rep (2003) 0.98
The universal nature, unequal distribution and antioxidant functions of melatonin and its derivatives. Mini Rev Med Chem (2013) 0.98
Obesity and metabolic syndrome: association with chronodisruption, sleep deprivation, and melatonin suppression. Ann Med (2011) 0.98
Neurotoxins: free radical mechanisms and melatonin protection. Curr Neuropharmacol (2010) 0.97
Sleep EEG changes after middle cerebral artery infarcts in mice: different effects of striatal and cortical lesions. Sleep (2006) 0.96
Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin. J Pineal Res (2011) 0.95
Increased balloon-induced inflammation, proliferation, and neointima formation in apolipoprotein E (ApoE) knockout mice. Stroke (2006) 0.94
Protective effects of melatonin in experimental free radical-related ocular diseases. J Pineal Res (2006) 0.94
ABCC1: a gateway for pharmacological compounds to the ischaemic brain. Brain (2008) 0.93
Melatonin and Parkinson's disease. Endocrine (2005) 0.93
INDOLE-3-ACETIC ACID INDUCIBLE 17 positively modulates natural leaf senescence through melatonin-mediated pathway in Arabidopsis. J Pineal Res (2014) 0.93
Dexmedetomidine-ketamine and midazolam-ketamine combinations for sedation in pediatric patients undergoing extracorporeal shock wave lithotripsy: a randomized prospective study. J Anesth (2010) 0.93
Potential role of dental stem cells in the cellular therapy of cerebral ischemia. Curr Pharm Des (2009) 0.92
Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin. J Neurochem (2006) 0.91
Purslane: a plant source of omega-3 fatty acids and melatonin. J Pineal Res (2005) 0.91
Melatonin promotes embryonic development and reduces reactive oxygen species in vitrified mouse 2-cell embryos. J Pineal Res (2012) 0.91
Role of drug efflux carriers in the healthy and diseased brain. Ann Neurol (2006) 0.91
Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions. J Pineal Res (2003) 0.91
Acute and delayed sulfur mustard toxicity; novel mechanisms and future studies. Interdiscip Toxicol (2008) 0.90
Orally administered melatonin reduces oxidative stress and proinflammatory cytokines induced by amyloid-beta peptide in rat brain: a comparative, in vivo study versus vitamin C and E. J Pineal Res (2003) 0.90
What constitutes a physiological concentration of melatonin? J Pineal Res (2003) 0.90
Melatonin combats molecular terrorism at the mitochondrial level. Interdiscip Toxicol (2008) 0.90
Oxidative damage to catalase induced by peroxyl radicals: functional protection by melatonin and other antioxidants. Free Radic Res (2003) 0.89
Protein phosphatase 1-dependent bidirectional synaptic plasticity controls ischemic recovery in the adult brain. J Neurosci (2008) 0.89
Melatonin induces class A1 heat-shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis. J Pineal Res (2015) 0.89
Calreticulin-melatonin. An unexpected relationship. Eur J Biochem (2003) 0.89
Prophylactic use of melatonin protects against focal cerebral ischemia in mice: role of endothelin converting enzyme-1. J Pineal Res (2004) 0.89
Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions. Neurobiol Dis (2011) 0.89
Melatonin reduces mortality and oxidatively mediated hepatic and renal damage due to diquat treatment. J Pineal Res (2007) 0.89
Antioxidant activity of melatonin in Chinese hamster ovarian cells: changes in cellular proliferation and differentiation. Biochem Biophys Res Commun (2003) 0.88
Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage. Pol J Pharmacol (2004) 0.88
Beneficial effects of melatonin in cardiovascular disease. Ann Med (2010) 0.88
Critical role of glutathione in melatonin enhancement of tumor necrosis factor and ionizing radiation-induced apoptosis in prostate cancer cells in vitro. J Pineal Res (2008) 0.88
Rifampicin attenuates brain damage in focal ischemia. Brain Res (2004) 0.87
Tissue-plasminogen activator-induced ischemic brain injury is reversed by melatonin: role of iNOS and Akt. J Pineal Res (2005) 0.87
Impaired mitochondrial complex III and melatonin responsive reactive oxygen species generation in kidney mitochondria of db/db mice. J Pineal Res (2011) 0.87
Urinary metabolites and antioxidant products of exogenous melatonin in the mouse. J Pineal Res (2006) 0.87
Abnormal circadian rhythm of melatonin in Smith-Magenis syndrome patients with RAI1 point mutations. Am J Med Genet A (2011) 0.86
Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia. J Pineal Res (2011) 0.86
Arabidopsis serotonin N-acetyltransferase knockout mutant plants exhibit decreased melatonin and salicylic acid levels resulting in susceptibility to an avirulent pathogen. J Pineal Res (2015) 0.86