Published in J Cell Sci on August 16, 2005
Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli. PLoS Pathog (2007) 2.01
Optimization of formaldehyde cross-linking for protein interaction analysis of non-tagged integrin beta1. J Biomed Biotechnol (2010) 1.27
N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: identification of the minimal N-glycosylation requirement for alpha5beta1. J Biol Chem (2009) 1.10
Sig1R protein regulates hERG channel expression through a post-translational mechanism in leukemic cells. J Biol Chem (2011) 0.91
Integrin ligands at a glance. J Cell Sci (2006) 4.76
Vinculin controls focal adhesion formation by direct interactions with talin and actin. J Cell Biol (2007) 4.28
Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments. Dev Cell (2007) 3.84
Demonstration of catch bonds between an integrin and its ligand. J Cell Biol (2009) 3.26
Synergistic control of cell adhesion by integrins and syndecans. Nat Rev Mol Cell Biol (2007) 3.21
Integrin structure, activation, and interactions. Cold Spring Harb Perspect Biol (2011) 2.58
Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix. J Cell Biol (2007) 2.33
Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Sci Signal (2009) 2.26
Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biol (2009) 2.16
Linking integrin conformation to function. J Cell Sci (2009) 2.15
Heparin-II domain of fibronectin is a vascular endothelial growth factor-binding domain: enhancement of VEGF biological activity by a singular growth factor/matrix protein synergism. Circ Res (2006) 2.08
SHARPIN is an endogenous inhibitor of β1-integrin activation. Nat Cell Biol (2011) 2.01
Integrin-specific signaling pathways controlling focal adhesion formation and cell migration. J Cell Biol (2003) 1.90
Fibronectin regulates latent transforming growth factor-beta (TGF beta) by controlling matrix assembly of latent TGF beta-binding protein-1. J Biol Chem (2005) 1.82
Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis. J Biol Chem (2003) 1.81
Conformational changes in the integrin beta A domain provide a mechanism for signal transduction via hybrid domain movement. J Biol Chem (2003) 1.80
Anti-integrin monoclonal antibodies. J Cell Sci (2009) 1.72
Lectin affinity as an approach to the proteomic analysis of membrane glycoproteins. J Proteome Res (2004) 1.68
Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain. J Biol Chem (2002) 1.65
Quantification of integrin receptor agonism by fluorescence lifetime imaging. J Cell Sci (2008) 1.64
Integrin alphavbeta1 is a receptor for foot-and-mouth disease virus. J Virol (2002) 1.60
Mass spectrometric characterization of proteins from the SARS virus: a preliminary report. Mol Cell Proteomics (2003) 1.49
Regulation of alpha5beta1 integrin conformation and function by urokinase receptor binding. J Cell Biol (2005) 1.44
Control of extracellular matrix assembly along tissue boundaries via Integrin and Eph/Ephrin signaling. Development (2009) 1.43
A specific alpha5beta1-integrin conformation promotes directional integrin translocation and fibronectin matrix formation. J Cell Sci (2004) 1.42
p190RhoGAP is the convergence point of adhesion signals from alpha 5 beta 1 integrin and syndecan-4. J Cell Biol (2008) 1.41
Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling. Biochem J (2002) 1.39
Proteomic-based identification of cleaved urinary beta2-microglobulin as a potential marker for acute tubular injury in renal allografts. Am J Transplant (2005) 1.39
Regulation of integrin function through conformational complexity: not simply a knee-jerk reaction? Curr Opin Cell Biol (2004) 1.38
Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1. J Biol Chem (2003) 1.36
Site-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis. Mol Cell Biol (2002) 1.35
Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins. J Biol Chem (2003) 1.32
A syndecan-4 hair trigger initiates wound healing through caveolin- and RhoG-regulated integrin endocytosis. Dev Cell (2011) 1.31
Integrin structure: heady advances in ligand binding, but activation still makes the knees wobble. Trends Biochem Sci (2003) 1.30
Evidence that monoclonal antibodies directed against the integrin beta subunit plexin/semaphorin/integrin domain stimulate function by inducing receptor extension. J Biol Chem (2004) 1.29
Rab5 mediates caspase-8-promoted cell motility and metastasis. Mol Biol Cell (2009) 1.28
Focal adhesions are sites of integrin extension. J Cell Biol (2010) 1.26
Requirement of podocalyxin in TGF-beta induced epithelial mesenchymal transition. PLoS One (2011) 1.25
Molecular interplay between endostatin, integrins, and heparan sulfate. J Biol Chem (2009) 1.25
Practical implementation of 2D HPLC scheme with accurate peptide retention prediction in both dimensions for high-throughput bottom-up proteomics. Anal Chem (2008) 1.24
Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration. J Cell Biol (2010) 1.24
The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubules. Am J Physiol Renal Physiol (2004) 1.24
The integrins of the urochordate Ciona intestinalis provide novel insights into the molecular evolution of the vertebrate integrin family. BMC Evol Biol (2005) 1.23
Proteomic analysis of Clostridium thermocellum core metabolism: relative protein expression profiles and growth phase-dependent changes in protein expression. BMC Microbiol (2012) 1.21
Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling. J Biol Chem (2008) 1.21
Identification of differentially expressed proteins in the cervical mucosa of HIV-1-resistant sex workers. J Proteome Res (2008) 1.18
Application of the StrOligo algorithm for the automated structure assignment of complex N-linked glycans from glycoproteins using tandem mass spectrometry. Rapid Commun Mass Spectrom (2003) 1.17
Giving off mixed signals--distinct functions of alpha5beta1 and alphavbeta3 integrins in regulating cell behaviour. IUBMB Life (2009) 1.14
Molecular basis for the dynamic strength of the integrin alpha4beta1/VCAM-1 interaction. Biophys J (2004) 1.14
RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex. J Cell Biol (2013) 1.13
Syndecan-4 phosphorylation is a control point for integrin recycling. Dev Cell (2013) 1.12
Deamidation of -Asn-Gly- sequences during sample preparation for proteomics: Consequences for MALDI and HPLC-MALDI analysis. Anal Chem (2006) 1.12
Mapping functional residues onto integrin crystal structures. Curr Opin Struct Biol (2003) 1.11
Investigating the role of P311 in the hypertrophic scar. PLoS One (2010) 1.10
The effect of laser profile, fluence, and spot size on sensitivity in orthogonal-injection matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun Mass Spectrom (2008) 1.09
Cell adhesion to fibrillin-1: identification of an Arg-Gly-Asp-dependent synergy region and a heparin-binding site that regulates focal adhesion formation. J Cell Sci (2007) 1.08
CD40 ligand binds to alpha5beta1 integrin and triggers cell signaling. J Biol Chem (2006) 1.08
Detection of subclinical tubular injury after renal transplantation: comparison of urine protein analysis with allograft histopathology. Transplantation (2007) 1.07
Use of peptide retention time prediction for protein identification by off-line reversed-phase HPLC-MALDI MS/MS. Anal Chem (2006) 1.07
Biochemical and proteomics approaches to characterize topoisomerase IIalpha cysteines and DNA as targets responsible for cisplatin-induced inhibition of topoisomerase IIalpha. Mol Pharmacol (2004) 1.07
Proteomic analysis of integrin adhesion complexes. Sci Signal (2011) 1.06
Sequence-specific retention calculator. A family of peptide retention time prediction algorithms in reversed-phase HPLC: applicability to various chromatographic conditions and columns. Anal Chem (2007) 1.06
Interaction of filamin A with the integrin beta 7 cytoplasmic domain: role of alternative splicing and phosphorylation. FEBS Lett (2004) 1.05
Cyclic mechanical reinforcement of integrin-ligand interactions. Mol Cell (2013) 1.05
An integrin-alpha4-14-3-3zeta-paxillin ternary complex mediates localised Cdc42 activity and accelerates cell migration. J Cell Sci (2009) 1.04
Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells. J Biol Chem (2004) 1.03
Defining the extracellular matrix using proteomics. Int J Exp Pathol (2013) 1.03
Automated structural assignment of derivatized complex N-linked oligosaccharides from tandem mass spectra. Rapid Commun Mass Spectrom (2002) 1.02
Syndecans shed their reputation as inert molecules. Sci Signal (2009) 1.02
Influenza virus induces apoptosis via BAD-mediated mitochondrial dysregulation. J Virol (2012) 1.01
Distinct roles of beta1 metal ion-dependent adhesion site (MIDAS), adjacent to MIDAS (ADMIDAS), and ligand-associated metal-binding site (LIMBS) cation-binding sites in ligand recognition by integrin alpha2beta1. J Biol Chem (2008) 1.00
Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver. J Proteome Res (2012) 1.00
Preconditioning injury-induced neurite outgrowth of adult rat sensory neurons on fibronectin is mediated by mobilisation of axonal alpha5 integrin. Mol Cell Neurosci (2007) 1.00
Novel activating and inactivating mutations in the integrin beta1 subunit A domain. Biochem J (2004) 0.99
Anti-Sa antibodies: prognostic and pathogenetic significance to rheumatoid arthritis. Arthritis Res Ther (2004) 0.98
Posttranslational modifications in lens fiber connexins identified by off-line-HPLC MALDI-quadrupole time-of-flight mass spectrometry. Invest Ophthalmol Vis Sci (2008) 0.98
Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment. Proteomics (2012) 0.98
Integrin-binding RGD peptides induce rapid intracellular calcium increases and MAPK signaling in cortical neurons. Mol Cell Neurosci (2006) 0.98
V490M, a common mutation in 3-phosphoglycerate dehydrogenase deficiency, causes enzyme deficiency by decreasing the yield of mature enzyme. J Biol Chem (2001) 0.98
Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway. J Cell Sci (2013) 0.97
Role of adhesion receptor trafficking in 3D cell migration. Curr Opin Cell Biol (2013) 0.97
Divalent cations regulate the folding and activation status of integrins during their intracellular trafficking. J Cell Sci (2011) 0.96
E-cadherin is a ligand for integrin alpha2beta1. Matrix Biol (2002) 0.96