Published in EMBO Rep on September 01, 2005
The endocytic matrix. Nature (2010) 3.15
Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer. Genes Dev (2009) 2.76
Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Nature (2009) 2.68
Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation. Genes Dev (2006) 2.20
Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors. Neuron (2007) 2.13
Numb regulates post-endocytic trafficking and degradation of Notch1. J Biol Chem (2009) 1.89
Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division. Nature (2009) 1.81
aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb. EMBO J (2007) 1.81
Notch signaling at a glance. J Cell Sci (2013) 1.76
Endocytosis and signaling: cell logistics shape the eukaryotic cell plan. Physiol Rev (2012) 1.61
Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis. Dev Cell (2011) 1.60
Endocytic regulation of Notch signaling. Curr Opin Genet Dev (2009) 1.59
Multiple Notch signaling events control Drosophila CNS midline neurogenesis, gliogenesis and neuronal identity. Development (2008) 1.26
A mosaic genetic screen for Drosophila neoplastic tumor suppressor genes based on defective pupation. Genetics (2007) 1.24
A screen for endocytic motifs. Traffic (2010) 1.15
Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain. Development (2010) 1.14
Endocytosis by Numb breaks Notch symmetry at cytokinesis. Nat Cell Biol (2012) 1.13
Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila. Genes Dev (2011) 1.08
Endocytosis and control of Notch signaling. Curr Opin Cell Biol (2012) 1.05
Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development (2011) 1.04
Numb independently antagonizes Sanpodo membrane targeting and Notch signaling in Drosophila sensory organ precursor cells. Mol Biol Cell (2010) 1.01
Temporal regulation of Drosophila IAP1 determines caspase functions in sensory organ development. J Cell Biol (2009) 1.01
The EGF repeat-specific O-GlcNAc-transferase Eogt interacts with notch signaling and pyrimidine metabolism pathways in Drosophila. PLoS One (2013) 0.99
Notch signalling in context. Nat Rev Mol Cell Biol (2016) 0.99
Caenorhabditis elegans num-1 negatively regulates endocytic recycling. Genetics (2008) 0.98
Sanpodo: a context-dependent activator and inhibitor of Notch signaling during asymmetric divisions. Development (2009) 0.94
Drosophila Hey is a target of Notch in asymmetric divisions during embryonic and larval neurogenesis. Development (2010) 0.90
dEHBP1 controls exocytosis and recycling of Delta during asymmetric divisions. J Cell Biol (2012) 0.88
Polarity mediates asymmetric trafficking of the Gbeta heterotrimeric G-protein subunit GPB-1 in C. elegans embryos. Development (2011) 0.88
Stress-induced switch in Numb isoforms enhances Notch-dependent expression of subtype-specific transient receptor potential channel. J Biol Chem (2009) 0.86
A fluorescent tagging approach in Drosophila reveals late endosomal trafficking of Notch and Sanpodo. J Cell Biol (2014) 0.85
Tools and methods for studying Notch signaling in Drosophila melanogaster. Methods (2014) 0.82
Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase. J Cell Biol (2013) 0.81
Interaction of Notch signaling modulator Numb with α-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells. J Biol Chem (2012) 0.80
Clathrin-mediated endocytosis and adaptor proteins. Acta Naturae (2013) 0.80
Adapting for endocytosis: roles for endocytic sorting adaptors in directing neural development. Front Cell Neurosci (2015) 0.79
Asymmetric cell division in the Drosophila bristle lineage: from the polarization of sensory organ precursor cells to Notch-mediated binary fate decision. Wiley Interdiscip Rev Dev Biol (2015) 0.79
How Drosophila melanogaster Forms its Mechanoreceptors. Curr Genomics (2008) 0.79
Golgi during development. Cold Spring Harb Perspect Biol (2011) 0.77
Drosophila neuroblasts as a new model for the study of stem cell self-renewal and tumour formation. Biosci Rep (2014) 0.76
Cell Fate Decision Making through Oriented Cell Division. J Dev Biol (2015) 0.76
Numb regulates the balance between Notch recycling and late-endosome targeting in Drosophila neural progenitor cells. Mol Biol Cell (2016) 0.75
Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b. Cell Res (2016) 0.75
Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear. Front Cell Neurosci (2015) 0.75
Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development (2000) 6.40
Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell (1994) 5.37
Nuclear access and action of notch in vivo. Cell (1998) 4.98
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron (1996) 4.69
Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity. Genes Dev (1995) 4.47
Gradient formation of the TGF-beta homolog Dpp. Cell (2000) 3.91
Regulation of notch signaling activity. Curr Biol (2004) 3.88
The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature (2003) 3.71
Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J Cell Biol (2003) 3.26
The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev Cell (2002) 3.16
numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell (1989) 2.72
Numb antagonizes Notch signaling to specify sibling neuron cell fates. Neuron (1996) 2.44
The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage. Proc Natl Acad Sci U S A (1996) 2.35
Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts. Nature (1999) 2.20
Revisiting the Drosophila microchaete lineage: a novel intrinsically asymmetric cell division generates a glial cell. Development (1999) 2.12
Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system. Cell (2001) 2.12
Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Curr Biol (2002) 2.09
prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila. Cell (1991) 2.08
Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division. Nat Cell Biol (2001) 1.96
Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation. Curr Biol (2004) 1.87
Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor. J Cell Biol (2004) 1.79
Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos. Curr Biol (1998) 1.76
Asymmetric cell division in the Drosophila nervous system. Nat Rev Neurosci (2001) 1.60
Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila. Dev Cell (2003) 1.42
The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization. Proc Natl Acad Sci U S A (1997) 1.29
Asymmetric localization and function of cell-fate determinants: a fly's view. Curr Opin Neurobiol (2004) 1.27
The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein. Development (1998) 1.11
Cerebral organoids model human brain development and microcephaly. Nature (2013) 9.07
Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell (2006) 4.52
The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature (2003) 3.71
The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell (2009) 3.60
The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev Cell (2002) 3.16
Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell (2005) 2.86
Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer. Genes Dev (2009) 2.76
Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell (2008) 2.74
Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Nature (2009) 2.68
Mitotic activation of the kinase Aurora-A requires its binding partner Bora. Dev Cell (2006) 2.57
The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila. Dev Cell (2008) 2.55
Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature (2008) 2.54
The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division. Dev Cell (2006) 2.53
Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. Dev Cell (2004) 2.39
Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors. Dev Cell (2005) 2.31
Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction. Curr Biol (2003) 2.20
Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Curr Biol (2002) 2.09
Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina. Neuron (2005) 2.06
Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Cell Stem Cell (2011) 2.02
Drosophila neuroblasts: a model for stem cell biology. Development (2012) 1.71
Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae. Curr Biol (2005) 1.65
Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron (2011) 1.60
Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins. Nat Cell Biol (2005) 1.56
The phosphatase PP4c controls spindle orientation to maintain proliferative symmetric divisions in the developing neocortex. Neuron (2013) 1.55
The Par complex and integrins direct asymmetric cell division in adult intestinal stem cells. Cell Stem Cell (2012) 1.47
The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila. Dev Cell (2006) 1.46
Heterotrimeric G proteins: new tricks for an old dog. Cell (2004) 1.23
FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal. Cell Rep (2012) 1.19
Spindle orientation in mammalian cerebral cortical development. Curr Opin Neurobiol (2012) 1.17
Fragile X protein functions with lgl and the par complex in flies and mice. Dev Cell (2005) 1.14
Endosome dynamics during development. Curr Opin Cell Biol (2006) 1.13
Lethal giant larvae take on a life of their own. Trends Cell Biol (2006) 1.07
The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements. Nat Cell Biol (2011) 1.05
Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila. Curr Biol (2005) 1.01
Quantitative analysis of protein dynamics during asymmetric cell division. Curr Biol (2005) 0.99
The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation. EMBO J (2013) 0.94
Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation. Genome Biol (2013) 0.89
Identification of transcription factor binding sites from ChIP-seq data at high resolution. Bioinformatics (2013) 0.89
Analysis and modeling of mitotic spindle orientations in three dimensions. Proc Natl Acad Sci U S A (2013) 0.89
Long-term live cell imaging and automated 4D analysis of drosophila neuroblast lineages. PLoS One (2013) 0.83
Pins for spines. Nat Cell Biol (2005) 0.81
Fly stem cell research gets infectious. Cell (2009) 0.81
LIS1 and spindle orientation in neuroepithelial cells. Cell Stem Cell (2008) 0.77
Wicked views on stem cell news. Nat Cell Biol (2009) 0.77
Neurobiology: getting axons going. Nature (2005) 0.75