Published in Cell on December 08, 2000
Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo. PLoS Biol (2006) 5.91
Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J Cell Biol (2003) 3.26
Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules. Nature (2009) 2.95
A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion. Nat Cell Biol (2011) 2.68
Thirty-one flavors of Drosophila rab proteins. Genetics (2007) 2.46
Amphiphysin is necessary for organization of the excitation-contraction coupling machinery of muscles, but not for synaptic vesicle endocytosis in Drosophila. Genes Dev (2001) 2.35
TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2. J Cell Biol (2002) 2.34
Endosomal entry regulates Notch receptor activation in Drosophila melanogaster. J Cell Biol (2008) 2.32
Shaping morphogen gradients by proteoglycans. Cold Spring Harb Perspect Biol (2009) 1.96
Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila. Dev Cell (2009) 1.95
Cytoneme-mediated contact-dependent transport of the Drosophila decapentaplegic signaling protein. Science (2014) 1.92
The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila. Dev Cell (2009) 1.90
Cdc42 and Par proteins stabilize dynamic adherens junctions in the Drosophila neuroectoderm through regulation of apical endocytosis. J Cell Biol (2008) 1.85
Sequential actions of BMP receptors control neural precursor cell production and fate. Genes Dev (2001) 1.84
Internalization is required for proper Wingless signaling in Drosophila melanogaster. J Cell Biol (2006) 1.82
Morphogen gradient formation. Cold Spring Harb Perspect Biol (2009) 1.81
Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction. Genes Dev (2003) 1.79
Hox control of organ size by regulation of morphogen production and mobility. Science (2006) 1.71
The extracellular regulation of bone morphogenetic protein signaling. Development (2009) 1.69
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors. Mol Biol Cell (2006) 1.68
Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface. Dev Biol (2007) 1.66
A specific protein substrate for a deubiquitinating enzyme: Liquid facets is the substrate of Fat facets. Genes Dev (2002) 1.66
Generation and dynamics of an endogenous, self-generated signaling gradient across a migrating tissue. Cell (2013) 1.62
Internalization-dependent and -independent requirements for transforming growth factor beta receptor signaling via the Smad pathway. Mol Cell Biol (2002) 1.58
The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity. PLoS One (2008) 1.53
Spatial range of autocrine signaling: modeling and computational analysis. Biophys J (2001) 1.52
Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs. EMBO Rep (2005) 1.49
Engineering gene networks to emulate Drosophila embryonic pattern formation. PLoS Biol (2005) 1.48
Compensatory flux changes within an endocytic trafficking network maintain thermal robustness of Notch signaling. Cell (2014) 1.47
The plant endosomal system--its structure and role in signal transduction and plant development. Planta (2004) 1.43
A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling. J Cell Biol (2009) 1.39
Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis. EMBO J (2006) 1.39
Visualization of an endogenous retinoic acid gradient across embryonic development. Nature (2013) 1.38
Control of Dpp morphogen signalling by a secreted feedback regulator. Nat Cell Biol (2010) 1.38
Quantitative approaches in developmental biology. Nat Rev Genet (2009) 1.34
Refined LexA transactivators and their use in combination with the Drosophila Gal4 system. Proc Natl Acad Sci U S A (2010) 1.31
Cleavages within the prodomain direct intracellular trafficking and degradation of mature bone morphogenetic protein-4. Mol Biol Cell (2004) 1.31
Crag regulates epithelial architecture and polarized deposition of basement membrane proteins in Drosophila. Dev Cell (2008) 1.28
Regulation of organ growth by morphogen gradients. Cold Spring Harb Perspect Biol (2010) 1.28
Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation. Hum Mol Genet (2009) 1.27
Free extracellular diffusion creates the Dpp morphogen gradient of the Drosophila wing disc. Curr Biol (2012) 1.22
Transforming growth factor beta depletion is the primary determinant of Smad signaling kinetics. Mol Cell Biol (2009) 1.21
Hsc70 is required for endocytosis and clathrin function in Drosophila. J Cell Biol (2002) 1.21
Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia. Nat Cell Biol (2013) 1.20
Dpp spreading is required for medial but not for lateral wing disc growth. Nature (2015) 1.18
The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development. Development (2010) 1.18
Cytonemes as specialized signaling filopodia. Development (2014) 1.17
Rab11 helps maintain apical crumbs and adherens junctions in the Drosophila embryonic ectoderm. PLoS One (2009) 1.16
Discrete models of autocrine cell communication in epithelial layers. Biophys J (2003) 1.16
Morphogen transport. Development (2013) 1.16
The J-domain protein Rme-8 interacts with Hsc70 to control clathrin-dependent endocytosis in Drosophila. J Cell Biol (2004) 1.16
Nuclear interpretation of Dpp signaling in Drosophila. EMBO J (2001) 1.15
A genetic screen in Drosophila for identifying novel components of the hedgehog signaling pathway. Genetics (2005) 1.14
Brinker requires two corepressors for maximal and versatile repression in Dpp signalling. EMBO J (2001) 1.14
Morphogen gradient interpretation by a regulated trafficking step during ligand-receptor transduction. Genes Dev (2005) 1.13
Extracellular movement of signaling molecules. Dev Cell (2011) 1.13
Drosophila melanogaster auxilin regulates the internalization of Delta to control activity of the Notch signaling pathway. J Cell Biol (2006) 1.12
Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila. EMBO J (2008) 1.12
Understanding morphogenetic growth control -- lessons from flies. Nat Rev Mol Cell Biol (2011) 1.12
Crumbs is required to achieve proper organ size control during Drosophila head development. Development (2010) 1.10
Dynamin participates in the maintenance of anterior polarity in the Caenorhabditis elegans embryo. Dev Cell (2009) 1.10
Drosophila Mtm and class II PI3K coregulate a PI(3)P pool with cortical and endolysosomal functions. J Cell Biol (2010) 1.09
The Drosophila Dead end Arf-like3 GTPase controls vesicle trafficking during tracheal fusion cell morphogenesis. Dev Biol (2007) 1.08
Visualisation and quantification of morphogen gradient formation in the zebrafish. PLoS Biol (2009) 1.07
The Drosophila BEACH family protein, blue cheese, links lysosomal axon transport with motor neuron degeneration. J Neurosci (2009) 1.06
Local BMP receptor activation at adherens junctions in the Drosophila germline stem cell niche. Nat Commun (2011) 1.06
The control of size in animals: insights from selector genes. Bioessays (2008) 1.05
Patched, the receptor of Hedgehog, is a lipoprotein receptor. Proc Natl Acad Sci U S A (2008) 1.05
Theoretical and experimental approaches to understand morphogen gradients. Mol Syst Biol (2008) 1.04
Building a morphogen gradient without diffusion in a growing tissue. PLoS One (2010) 1.04
Quantification of biological interactions with particle image cross-correlation spectroscopy (PICCS). Biophys J (2011) 1.03
Membrane-associated non-receptors and morphogen gradients. Bull Math Biol (2006) 1.03
Formation of the long range Dpp morphogen gradient. PLoS Biol (2011) 1.03
Direct detection of guidance receptor activity during border cell migration. Proc Natl Acad Sci U S A (2010) 1.01
Rho1 regulates signaling events required for proper Drosophila embryonic development. Dev Biol (2005) 0.99
Epithelial septate junction assembly relies on melanotransferrin iron binding and endocytosis in Drosophila. Nat Cell Biol (2010) 0.98
A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein. Mol Biol Cell (2002) 0.98
The SHORT-ROOT protein acts as a mobile, dose-dependent signal in patterning the ground tissue. Proc Natl Acad Sci U S A (2012) 0.97
Drosophila CK1-γ, gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking. J Cell Biol (2012) 0.97
Intestinal epithelium-derived BMP controls stem cell self-renewal in Drosophila adult midgut. Elife (2014) 0.96
Quantification of growth asymmetries in developing epithelia. Eur Phys J E Soft Matter (2009) 0.95
Aggregation of a Distributed Source in Morphogen Gradient Formation. SIAM J Appl Dyn Syst (2005) 0.95
Organ Size Control: Lessons from Drosophila. Dev Cell (2015) 0.95
Ectopic expression of inhibitors of protein phosphatase type 1 (PP1) can be used to analyze roles of PP1 in Drosophila development. Genetics (2003) 0.95
Spatial discontinuity of optomotor-blind expression in the Drosophila wing imaginal disc disrupts epithelial architecture and promotes cell sorting. BMC Dev Biol (2010) 0.94
Cell lineage transport: a mechanism for molecular gradient formation. Mol Syst Biol (2006) 0.93
Phosphoinositide regulation of integrin trafficking required for muscle attachment and maintenance. PLoS Genet (2011) 0.92
Communicating by touch--neurons are not alone. Trends Cell Biol (2014) 0.92
Relay of retrograde synaptogenic signals through axonal transport of BMP receptors. J Cell Sci (2012) 0.91
The nuclear protein Waharan is required for endosomal-lysosomal trafficking in Drosophila. J Cell Sci (2010) 0.88
Rab5-mediated endocytosis of activin is not required for gene activation or long-range signalling in Xenopus. Development (2009) 0.88
Localized Ectopic Expression of Dpp Receptors in a Drosophila Embryo. Stud Appl Math (2009) 0.87
Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling. Mol Biol Cell (2012) 0.87
Endocytosis and signaling during development. Cold Spring Harb Perspect Biol (2014) 0.87
New insights into extracellular and post-translational regulation of TGF-β family signalling pathways. J Biochem (2013) 0.86
Uptake of the necrotic serpin in Drosophila melanogaster via the lipophorin receptor-1. PLoS Genet (2009) 0.86
Forming and interpreting gradients in the early Xenopus embryo. Cold Spring Harb Perspect Biol (2009) 0.86
Regulation of Dpp activity by tissue-specific cleavage of an upstream site within the prodomain. Dev Biol (2010) 0.86
The effect of the signalling scheme on the robustness of pattern formation in development. Interface Focus (2012) 0.86
The redistribution of Drosophila vesicular monoamine transporter mutants from synaptic vesicles to large dense-core vesicles impairs amine-dependent behaviors. J Neurosci (2014) 0.85
Dynamics of Dpp signaling and proliferation control. Science (2011) 3.48
Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division. Nature (2009) 1.81
Robust formation of morphogen gradients. Phys Rev Lett (2005) 1.26
Identical transacting factor requirement for knirps and knirps-related Gene expression in the anterior but not in the posterior region of the Drosophila embryo. Mech Dev (1994) 1.17
Number, identity, and sequence of the Drosophila head segments as revealed by neural elements and their deletion patterns in mutants. Proc Natl Acad Sci U S A (1994) 1.10
Quantification of growth asymmetries in developing epithelia. Eur Phys J E Soft Matter (2009) 0.95
Anthrax toxin receptor 2a controls mitotic spindle positioning. Nat Cell Biol (2012) 0.92
Morphogen transport in epithelia. Phys Rev E Stat Nonlin Soft Matter Phys (2007) 0.90
The missing link: implementation of morphogenetic growth control on the cellular and molecular level. Curr Opin Genet Dev (2011) 0.83
Embryonic limb development in Drosophila. Trends Genet (1993) 0.75